Mobile phone surveys: The Slovenian case study

In 2004, the number of mobile phone subscriptions in Slovenia reached the total number of inhabitants. Consequently, the fixed telephone coverage has started to decline; almost 10% of households are now available only over the mobile phone. With this, Slovenia positions itself as a typical EU country and can serve as a case study for issues related to mobile phone interview surveys. The paper addresses the general context of mobile phone usage and the calculations of mobile phone coverage rates. It also discusses the non-coverage problems related to mobile and mobile-only households. It is shown, that even with a relatively small non-coverage the corresponding estimates can be considerably biased, as in the case of the unemployment rate in the Slovenian Labour Force Survey. There are severe methodological problems with mobile phone interview surveys. In particular, a pilot mobile phone survey confirmed the disadvantages of costs, frames and response rates, at least when compared to fixed telephone surveys. In addition, the response rates are dramatically lower for less intensive mobile phone users. The comparisons of respondents in mobile phone surveys with the corresponding sub-samples in Labour Force Surveys and in fixed telephone surveys revealed some specific discrepancies in the socio-demographic structure. Due to non-coverage, the respondents in the mobile phone survey tend to be younger, higher educated, from larger households and are represented by a larger share of males. The non-response mechanism can additionally reinforce these effects (e.g, gender), however it can also cancel them (e.g., age, household size). Special complexity arises from the diverse effects of the non-response components (refusal vs. non-contact). According to their attitudes towards mobile phone use, mobile phone users compose three distinct segments (intensive pragmatic and emotional users, less intensive users) that may behave differentially also during the mobile phone survey process.

415. A Whole Genome Sequencing Analysis of a Multi-unit Long-term Care Facility COVID-19 Outbreak

Background The coronavirus disease (COVID-19) pandemic has affected residents in long-term care facilities (LTCF) significantly. Understanding transmission dynamics in this setting is crucial to control the spread of COVID-19 in this population. Using whole genome sequencing (WGS) of SARS-CoV-2, we aimed to delineate the points of introduction and transmission pathways in a large LTCF in Quebec, Canada. Methods Between 2020-10-28 and 2021-01-09, COVID-19 cases occurred in 102 residents and 111 HCW at a 387-bed LTCF; cases were distributed in 11 units on 6 floors. As part of outbreak analysis, SARS-CoV-2 isolates underwent WGS using the Oxford Nanopore Minion and the Artic V3 protocol. Lineage attribution and sequence types (ST, within 3 mutations) were assigned based on Pangolin classification and variant analysis. Epidemiologic data including date of positive PCR test, resident room number and HCW work location were collected. Self-reported high-risk exposures were collected by HCW questionnaire via phone interview after consent. Cases and their ST, geo-temporal relations and HCW-reported exposures were examined via network plots and geography-based epidemic curves to infer points of introduction and paths of transmission. Results Of 170 isolates available from 100/102 residents and 70/111 HCW, 130 (76.4%) were successfully sequenced. Phylogenetic analysis revealed 7 separate introductions to the LTCF. Grouping of ST by units was observed, with temporal appearance of ST supporting HCW introduction in 7/11 units. Proportion of phone interview completion was low at 35% (26/70). Few HCW recalled specific high-risk exposures. Recalled exposures supported by genetic linkage revealed potential between-unit introductions from HCW-to-HCW transmission at work and outside the workplace (e.g. carpooling). On one unit, a wandering resident was identified as a likely source of transmission to other residents (Figure 1). Network plot of cases clustered by geographic unit, colour-coded by sequence type. Circles represent residents; addition signs represent healthcare workers. Blue lines represent identified high-risk exposures. Node labels represent floor and unit identifiers; 2 units per floor. Conclusion We demonstrate the complex genomic epidemiology of a multi-unit LTCF outbreak, putting into evidence the importance of a multi-faceted approach to limit transmission. This analysis highlights the utility of using WGS to uncover unsuspected transmission routes, such as HCW contact outside work, which can prompt new infection control measures. Disclosures All Authors: No reported disclosures

Rheumatoid Arthritis, as a Clinical Disease, but Not Rheumatoid Arthritis-associated Autoimmunity is Linked to Cardiovascular Events

Background: Rheumatoid Arthritis (RA) is characterized by increased cardiovascular (CV) mortality. CV events are particularly high in patients with RA-specific autoimmunity, including rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA), raising the question whether RA-specific autoimmunity itself is associated with CV events.Methods: New CV events (myocardial infarction, stroke or death by CV cause) were recorded in 20,625 subjects of the Electricité de France – Gaz de France (GAZEL) cohort. Self-reported RA cases in the GAZEL cohort were validated by phone interview on the basis of a specific questionnaire. In 1,618 subjects, in whom serum was available, RF and ACPA were measured. A piecewise exponential Poisson regression was used to analyze the association of CV events with presence of RA as well as RA-specific autoimmunity (without RA).Results: CV events in GAZEL were associated with age, male sex, smoking, hypertension, hyperlipidemia and diabetes mellitus (HR from 1.06 to 1.87, p < 0.05). Forty-two confirmed RA cases were identified. Confirmed RA was significantly associated with CV risk increase (HR of 3.03; 95% CI: 1.13-8.11, p=0.03) independently of conventional CV risk factors. One hundred seventy-eight subjects showed RF or ACPA positivity without presence of RA. CV events were not associated with ACPA positivity (HR: 1.52, 95% CI: 0.47-4.84, p= 0.48) or RF positivity (HR: 1.15, 95% CI: 0.55-2.40, p= 0.70) in the absence of RA.Conclusions: RA, as a clinical chronic inflammatory disease, but not mere positivity for RF or ACPA in the absence of clinical disease is associated with increased CV risk.

Incidence of De Quervain’s Thyroiditis in an Area With High Prevalence of Sars-Cov-2 Infection

Purpose: To evaluate the possible association between Covid-19 infection and subacute thyroiditis. Patients and Methods: We reviewed the medical and imaging records of patients referred to our outpatient setting dedicated to “thyroid emergency” (“bollini verdi”) from April 2020 to October 2020 of our Department. This out-patient clinic is devoted to patients who required an evaluation for severe hypothyroidism, thyrotoxicosis and neck discomfort or pain. All patients with a newly diagnosed subacute thyroiditis were selected. A retrospective collection of the data of all patients receiving a diagnosis of subacute thyroiditis was performed taking into account the same period of time (April-October) starting from 2016.Results: During the COVID-19 outbreak in our Region, (April 2020 to October 2020), 396 patients attended the out-patient emergency clinic. Among them, 10 (2.7%) patients received a diagnosis of subacute thyroiditis. In a single patient, a 44 yr old man, Covid-19 pulmonary infection had been diagnosed seven weeks before the diagnosis of subacute thyroiditis. All of the remaining patients were and still are Covid-19 free as confirmed by phone interview. The percentage of patients who received diagnosis of subacute thyroiditis in the same period starting from 2016 was superimposable (2.9%, 2.9%, 2.6% and 3.0% in 2016, 2017, 2018 and 2019, respectively). Conclusions: Our data do not demonstrate an increase of the incidence of subacute thyroiditis in Brescia areas, a region with the highest prevalence of COVID-19 in Italy during the period of the pandemic outbreak.Trial registration: no. 4631

A conservative treatment for chronic obstructive sialoadenitis by intraductal instillation of mucolytic, steroids and antibiotic solution

Purposes Reporting our experience in treating chronic obstructive sialadenitis with a protocol consisting of sialoendoscopy and intraductal instillation of antibiotics, steroids and n-acetyl-cysteine (NAC) solution. Methods Prospective study of patients with chronic obstructive sialadenitis with no apparent lithiasic obstructions, with recurrent non-lithiasic sialoadenitis and patients with lithiasic sialoadenitis not solved with sialoendoscopy. In all cases, a sialoendoscopy was performed. All the patients affected by lithiasic sialoadenitis where the chronic inflammation was resolved with sialoendoscopy were excluded from the study. The mid-term follow-up was performed at 12 months via phone interview, to understand whether patients had developed any further symptoms after the treatment. Results This study included 26 patients. All the patient without sialolithiasis have not reported any symptoms during the follow-up period. Two of those with sialolithiasis have not shown any signs of recurrence. The remaining three patients with non-resolved sialolithiasis had a recurrence of symptoms which were treated again with 1 intraductal administration of betamethasone, gentamicine and NAC, showing immediately a regression of the symptoms. Conclusions Intraductal administration of gentamicin + NAC + betamethasone seemed effective for the therapy of chronic obstructive sialoadenitis. Our protocol seemed effective also in that cases where it was not possible to remove or detect endoscopically an obstruction. In all these cases we have noticed an increase in the symptom-free time even in cases where it was not possible to remove the stones.

Moving toward gender fluid discourses in early childhood settings: ECES share their experiences and ideas

The dominant, yet dated discourse surrounding gender has been discussed primarily using developmental theory. Over the last thirty years, scholars have been challenging this discourse, but this is often not reflected in practice. This qualitative study is informed by a phone interview and a focus group session with educators, who believe that adopting a more gender fluid perspective with children is important. Inspired by Queer theory, employing a critical paradigm and social justice framework, it investigates how a queering of current gender discourses is being incorporated into ECEC practice. By consulting educators, the research gains insight on how gender fluid discourses can be incorporated into the field of ECEC through learning how educators are already incorporating gender fluid discourses in a proactive manor with preschool age children in ECEC settings. In the findings, five main themes were identified focusing on materials, practices, parents, ECEs, and ECE education and support. Keywords: early childhood education and care, educators, gender fluid, reconceptualizing

Moving toward gender fluid discourses in early childhood settings: ECES share their experiences and ideas

The dominant, yet dated discourse surrounding gender has been discussed primarily using developmental theory. Over the last thirty years, scholars have been challenging this discourse, but this is often not reflected in practice. This qualitative study is informed by a phone interview and a focus group session with educators, who believe that adopting a more gender fluid perspective with children is important. Inspired by Queer theory, employing a critical paradigm and social justice framework, it investigates how a queering of current gender discourses is being incorporated into ECEC practice. By consulting educators, the research gains insight on how gender fluid discourses can be incorporated into the field of ECEC through learning how educators are already incorporating gender fluid discourses in a proactive manor with preschool age children in ECEC settings. In the findings, five main themes were identified focusing on materials, practices, parents, ECEs, and ECE education and support. Keywords: early childhood education and care, educators, gender fluid, reconceptualizing

Uncloaking the anxiety behind professional dress.

Graduating from university is one of life’s greatest milestones. Students expect their stress to subside upon graduation; however, the transition from student life to career track entails a new set of stressful circumstances, including how to dress professionally. Using a mixed methods approach, this study examined how recent graduates prepare their clothing for the professional workplace. Participants included 15 recent, professionally employed, postsecondary female graduates who completed a demographic questionnaire, a modified version of a standardized anxiety scale, and a phone interview. In order to determine best wardrobe practices, research included interviews with 5 fashion advisors. Although results revealed recent graduates did not experience any quantitatively significant anxiety, interview responses demonstrated both concern and uncertainty. This research provides insight into the lived experience of recent female graduates. Findings may be used to assist retailers, create guides, and develop workshops for new graduates entering the professional realm.

Uncloaking the anxiety behind professional dress.

Graduating from university is one of life’s greatest milestones. Students expect their stress to subside upon graduation; however, the transition from student life to career track entails a new set of stressful circumstances, including how to dress professionally. Using a mixed methods approach, this study examined how recent graduates prepare their clothing for the professional workplace. Participants included 15 recent, professionally employed, postsecondary female graduates who completed a demographic questionnaire, a modified version of a standardized anxiety scale, and a phone interview. In order to determine best wardrobe practices, research included interviews with 5 fashion advisors. Although results revealed recent graduates did not experience any quantitatively significant anxiety, interview responses demonstrated both concern and uncertainty. This research provides insight into the lived experience of recent female graduates. Findings may be used to assist retailers, create guides, and develop workshops for new graduates entering the professional realm.

Older Adults’ Loneliness in Early COVID-19 Social Distancing: Implications of Rurality

Objectives Older adults face greater health risks due to coronavirus disease 2019 (COVID-19), yet preventative social distancing measures may cause increased social isolation, potentially heightening risk of loneliness. In this mixed-methods study we examine changes in older adults’ loneliness due to social distancing, explore variability in perceptions, and identify whether such changes differ by rurality. Methods A Midwestern sample of 76 older adults aged 70–97 (mean age = 82; 74% female; 95% White; 39% rural) completed a phone interview about their experiences with social distancing due to COVID-19. Interviews were conducted during early weeks of regional social distancing. Participants completed retrospective and current assessments of loneliness, including providing explanations of their responses. Results On average, loneliness increased during early social distancing, yet variability was evident. Those experiencing increased loneliness described a feeling of loss or lack of control, whereas those experiencing stability in loneliness identified adaptability in social connection modes or feeling accustomed to social isolation. Rural older adults experienced a significantly smaller increase in loneliness than their nonrural counterparts. Discussion These findings suggest nuanced experiences among older adults, but generally negative implications for loneliness. Interventions to address older adults’ social isolation and loneliness during COVID-19 are warranted.