scholarly journals A Comprehensive Review on Anti-Inflammatory Activity of The Traditional Plants Plumbago zeylanica(Chitra)

2021 ◽  
Vol 22 (1) ◽  
Keyword(s):  
Bioactive Compounds ◽  
Pharmacological Action ◽  
Comprehensive Understanding ◽  
High Demand ◽  
Plumbago Zeylanica ◽  
Wide Range ◽  
Anti Cancer ◽  
Long Time ◽  
Medicinal Properties ◽  
Anti Inflammatory

Medicinal plants have long been utilised as a source of medicine and are in high demand throughout the world. They've been around for a long time, and they've been utilised to cure and prevent ailments. Plumbago zeylanica is a medicinal plant that is frequently utilised for its medicinal properties. It contains several bioactive compounds like napthoquinones, flavonoids, alkaloids, glycosides, steroids, tri-terpenoids, tannins, fixed oils, fats, proteins, etc. among all plumbagin is most important bioactive compounds. It possesses wide range of pharmaceutical activities such as anti-inflammatory, antimicrobial, anti-cancer, anti-ulcer, antidiabetic etc. Several investigations on its pharmacological activity have been conducted. The goal of this review is to provide a comprehensive understanding of P. zeylanica's chemical composition and pharmacological action.

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

scholarly journals Zanjabeel (Zingiber officinale Roscoe.): An Evidence-Based Review of Anti-nociceptive, Anti-inflammatory, Antioxidant, and Antimicrobial Properties

2021 ◽  
pp. 26-35
Author(s):  
Fatima Khan ◽  
Mohd Nayab ◽  
Abdul Nasir Ansari
Keyword(s):  
Therapeutic Potential ◽  
Antioxidant Properties ◽  
Plant Secondary Metabolites ◽  
Zingiber Officinale ◽  
Extensive Study ◽  
The Body ◽  
Wide Range ◽  
Zingiber Officinale Roscoe ◽  
Medicinal Properties ◽  
Anti Inflammatory

Ginger has been appreciated for over 2500-3000 years in many parts of the world due to its numerous scientific properties. The ginger plant (Zingiber officinale Roscoe) belongs to the Zingiberaceae family. It is a known food and flavoring ingredient reputed for its wide range of medicinal properties that have been widely used in Chinese, Ayurvedic, and Unāni Tibb worldwide, since antiquity. Ginger has long been used to cure a variety of ailments, including diarrhea, stomach discomfort, indigestion, and nausea. It is a versatile herb with phenomenal phytotherapeutic and medicinal properties. Active ingredients available in ginger such as 6-gingerol, 6-shogaol, 6-paradol, and zingerone are responsible for upgrading enzyme actions and balancing circulation through rejuvenating the body with physical re-strengthening. Gingerols, the key phenolic plant secondary metabolites responsible for its distinct flavor and health benefits, are found in the rhizome of ginger Extensive study has been undertaken over the last two decades to uncover bioactive ingredients and the therapeutic potential of ginger. This review considers ginger's chemical composition and the most recent study findings on its possible health advantages, such as analgesic, anti-inflammatory, antibacterial, and antioxidant properties due to its phytochemistry. Overall, clinical trials are needed to confirm these prospective various health advantages of ginger in human subjects and the most efficacious dosage, based on the current body of scientific literature.

scholarly journals Medicinal properties of Abutilon indicum

2018 ◽  
Vol 1 (1) ◽  
pp. 1-4
Author(s):  
S Rajeshwari ◽  
SP Sevarkodiyone
Keyword(s):  
Medicinal Plant ◽  
Traditional Medicine ◽  
Phytochemical Analysis ◽  
Vaginal Infections ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Medicinal Properties ◽  
Anti Inflammatory ◽  
Larvicidal Activities ◽  
Abutilon Indicum

Abutilon indicum is a common Indian shrub, belonging to the family Malvaceae; Also known as Mallow in english, Abutilon indicum is used as a medicinal plant. It has been extensively used as a traditional medicine as a laxative, emollient, analgesic, anti-diabetic, anti-inflammatory and blood tonic agent and also in the treatment of leprosy, urinary disease, jaundice, piles, relieving thirst, cleaning wounds and ulcers, vaginal infections, diarrhea, rheumatism, mumps, pulmonary tuberculosis, bronchitis, allergy, blood dysentery, some nervous and some ear problems. Various studies on the plant extract have been performed to confirm the anti-oxidant, anti-bacterial, analgesic, anti-inflammatory, anti-cancer, hepato-protective, immuno-modulatory and larvicidal activities of the plant. This plant is often used as a medicinal plant and is considered invasive on certain tropical islands. In traditional medicine, A. indicum is used as a aphrodisiac, demulcent, diuretic, laxative, pulmonary and sedative (leaves). The bark is astringent and diuretic; laxative, expectorant and demulcent (seeds); laxative and tonic, anti-inflammatory and anthelmintic (plant); analgesic (fixed oil); diuretic and for leprosy (roots). The plant is very much used in Siddha medicines. In fact, the bark, root, leaves, flowers and seeds are all used for medicinal purposes by Tamils. The leaves are also used to treat for pile complaints. The flowers are traditionally used to increase semen in men. The phytochemical analysis showed the Presence of Alkaloid, Saponins, Amino acid, Flavonoids, Glycosides and steroids. This plant exhibits several potential pharmacological activities. A review on the various studies on the plant has been provided for the purpose of understanding its medicinal properties.

Recent Developments on the Synthesis of Biologically Significant bis/tris(indolyl)methanes under Various Reaction Conditions: A Review

2020 ◽  
Vol 24 (6) ◽  
pp. 583-621
Author(s):  
Arvind Singh ◽  
Gurpreet Kaur ◽  
Bubun Banerjee
Keyword(s):  
Ionic Liquids ◽  
Bioactive Compounds ◽  
Building Block ◽  
Heterogeneous Catalysts ◽  
Metal Catalysts ◽  
Reaction Conditions ◽  
Naturally Occurring ◽  
Wide Range ◽  
Anti Cancer ◽  
Recent Developments

Bis(indolyl)methane skeleton is the main building block of many naturally occurring bioactive compounds. Bis(indolyl)methanes are found to possess a wide range of pharmaceuitical efficacies. These important scaffolds are being used as anti-cancer, antioxidant, anti-bacterial, anti-inflammatory, and anti-proliferative agents. In this review, we summarized the latest developments on the synthesis of various bis/tris(indolyl)methane derivatives from the reactions of two equivalents of indoles and one equivalent of aldehydes or indole-3-carbaldehydes under various reaction conditions. More than hundred different catalysts were employed for these transformations which include various metal catalysts, ionic liquids, organocatalysts, surfactants, homogeneous, heterogeneous catalysts etc.

EXTRACTION AND EVALUATION OF ANTI INFLAMMATORY ACTIVITY OF SPATHIPHYLLUM CANNIFOLIUM

2015 ◽  
Vol 77 (24) ◽  
Author(s):  
Raha Ahmad Raus ◽  
Norhayati Abdullah ◽  
Nurul Fakhriah Ismail ◽  
Munira Shahbuddin
Keyword(s):  
Optimum Condition ◽  
Bioactive Compounds ◽  
Bioactive Compound ◽  
Inflammatory Activity ◽  
Chloroform Fraction ◽  
Landscape Plant ◽  
Anti Cancer ◽  
Anti Inflammatory ◽  
Face Centered ◽  
Central Composite

Sphathiphyllum cannifolium is abundantly planted in Malaysia as a landscape plant. However, this plant also has medical benefit to human as it was previously found to possess anti-bacteria and anti-cancer activities. In the present study, the plant was evaluated for its anti inflammatory activity and the optimum condition for the extraction of bioactive compounds with anti inflammatory activity was determined. Semi purification of the compounds possessing anti inflammatory activity was conducted as well. To extract the bioactive compound, sonication with methanol as a solvent extraction was carried out. Face-Centered Central Composite Design (FCCCD) and Response Surface Methodology (RSM) were used to design and identify the optimum condition to extract the compound, respectively. The results showed that the plant was positive for the anti inflammatory activity with IC50 6.3 µg/ml. Sonication for 60 min at 40°C using medium frequency was the optimum condition to carry out the extraction for bioactive compounds. After semi purification of the initial crude extract by solvent partitioning, chloroform fraction was found to be positive for anti inflammatory activity. In conclusion, this study suggested that S. cannifolium possess anti inflammatory activity and should be further analyzed to identify the specific compounds that responsible for this activity.   

scholarly journals Medicinal Properties and Bioactive Compounds from Wild Mushrooms Native to North America

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 251
Author(s):  
Mehreen Zeb ◽  
Chow H. Lee
Keyword(s):  
Drug Discovery ◽  
North America ◽  
Bioactive Compounds ◽  
Ecological Systems ◽  
Good Source ◽  
Mushroom Species ◽  
Long Time ◽  
Bioactive Ingredients ◽  
Medicinal Properties ◽  
Different Cultures

Mushrooms, the fruiting bodies of fungi, are known for a long time in different cultures around the world to possess medicinal properties and are used to treat various human diseases. Mushrooms that are parts of traditional medicine in Asia had been extensively studied and this has led to identification of their bioactive ingredients. North America, while home to one of the world’s largest and diverse ecological systems, has not subjected its natural resources especially its diverse array of mushroom species for bioprospecting purposes: Are mushrooms native to North America a good source for drug discovery? In this review, we compile all the published studies up to September 2020 on the bioprospecting of North American mushrooms. Out of the 79 species that have been investigated for medicinal properties, 48 species (60%) have bioactivities that have not been previously reported. For a mere 16 selected species, 17 new bioactive compounds (10 small molecules, six polysaccharides and one protein) have already been isolated. The results from our literature search suggest that mushrooms native to North America are indeed a good source for drug discovery.

scholarly journals Phytochemicals and Biological Activities of Garcinia morella (Gaertn.) Desr.: A Review

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5690
Author(s):  
Hosakatte Niranjana Murthy ◽  
Dayanand Dalawai ◽  
Yaser Hassan Dewir ◽  
Abdullah Ibrahim
Keyword(s):  
Organic Acids ◽  
Bioactive Compounds ◽  
Phenolic Acids ◽  
Biological Activities ◽  
Active Constituents ◽  
Evergreen Tree ◽  
Wide Range ◽  
Anti Inflammatory ◽  
Larvicidal Activities ◽  
Seed Extracts

Garcinia morella (Gaertn.) Desr. is an evergreen tree that yields edible fruits, oil, and resin. It is a source of “gamboge”, a gum/resin that has a wide range of uses. The fruits, leaves, and seeds of this tree are rich in bioactive compounds, including xanthones, flavonoids, phenolic acids, organic acids, and terpenoids. Evidence from different studies has demonstrated the antioxidant, antifungal, antiviral, hepatoprotective, anticancer, anti-inflammatory, antibacterial, and larvicidal activities of the fruit, leaf, and seed extracts of G. morella. This review summarizes the information on the phytochemicals of G. morella and the biological activities of its active constituents.

scholarly journals Coral and Coral-Associated Microorganisms: A Prolific Source of Potential Bioactive Natural Products

Marine Drugs ◽  
2019 ◽  
Vol 17 (8) ◽  
pp. 468 ◽  
Author(s):  
Sang ◽  
Dat ◽  
Vinh ◽  
Cuong ◽  
Oanh ◽  
...  
Keyword(s):  
Natural Products ◽  
Bioactive Compounds ◽  
Marine Invertebrates ◽  
Present Review ◽  
Bioactive Natural Products ◽  
Wide Range ◽  
Anti Inflammatory

Marine invertebrates and their associated microorganisms are rich sources of bioactive compounds. Among them, coral and its associated microorganisms are promising providers of marine bioactive compounds. The present review provides an overview of bioactive compounds that are produced by corals and coral-associated microorganisms, covering the literature from 2010 to March 2019. Accordingly, 245 natural products that possess a wide range of potent bioactivities, such as anti-inflammatory, cytotoxic, antimicrobial, antivirus, and antifouling activities, among others, are described in this review.

scholarly journals A REVIEW ON ALOE VERA-THE WONDER MEDICINAL PLANT

2018 ◽  
Vol 8 (5-s) ◽  
pp. 94-99 ◽  
Author(s):  
Suseela Lanka
Keyword(s):  
Amino Acids ◽  
Medicinal Plant ◽  
Genital Herpes ◽  
Bioactive Compounds ◽  
Seborrheic Dermatitis ◽  
Aloe Vera ◽  
Medicinal Uses ◽  
Succulent Plant ◽  
Long Time ◽  
Medicinal Properties

Aloe vera, a succulent plant that grows in arid and subtropical climates is best known for its medicinal properties and is used in Ayurvedic, Homoeopathic and Allopathic streams of medicine. It has been in use for a long time by people of varied cultures and traditional uses include applications to reduce perspiration, oral dosing for diabetes and to get rid of a range of gastrointestinal ailments. It is also used to treat burn wounds, minor cuts, genital herpes, and seborrheic dermatitis. The leaves of this wonderful medicinal plant contain numerous vitamins, minerals, natural sugars, enzymes, amino acids, and as well rich in various bioactive compounds that exhibit emollient, purgative, anti-inflammatory, antioxidant, antimicrobial, anti-helmenthic, antifungal, aphrodisiac, antiseptic and cosmetic values. Many cosmetic industries widely use this plant owing to its healing and nourishing properties.  Keywords: Aloe vera, Medicinal Uses, bioactive compounds, Cosmetic industries

scholarly journals A Review: The extraction of active compound from Cymbopogon sp. and its potential for medicinal applications

2018 ◽  
Vol 5 (1) ◽  
pp. 82-98
Author(s):  
Shuhada A. Muttalib ◽  
Raihana Edros ◽  
Nor Azah M. A. ◽  
Rajaletchumy V. Kutty
Keyword(s):  
Pharmaceutical Industry ◽  
Bioactive Compounds ◽  
Plant Extracts ◽  
Active Compound ◽  
Biological Activities ◽  
Cymbopogon Citratus ◽  
High Demand ◽  
Pharmacological Activities ◽  
Wide Range ◽  
The Family

Cymbopogon citratus and Cymbopogon nardus are plants categorized under the family of Poaceae that have been recognized with high demand in pharmaceutical industry for its wide range of pharmacological activities. The potential bioactive compounds can be obtained either through traditional or conventional methods. The plant extracts are commonly used in numbers of products for culinary, pesticides and cosmetic purposes for its flavours and fragrances. Besides, bioactive compounds extracted from both species possess good biological activities that can be applied in the pharmaceutical field.

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