Cognitive Influences in Parkinson's Disease Patients and Their Caregivers: Perspectives From an Australian Cohort

Objectives: Cognitive impairment impacts negatively on Parkinson's disease (PD) patient and caregiver quality of life (QoL). We examined cognitive impairment in PD patients and their caregivers to determine if caregiver cognition affected their PD relative.Methods: Validated cognition and clinical outcome measures were assessed in 103 PD patients and 81 caregivers.Results: PD patients showed more cognitive impairment than their carers, with 48.6% having possible Mild Cognitive Impairment (MCI) and 16.5% having PD dementia. Increasing age, male gender, lower education level, various non-motor symptoms and certain therapies, associated with poorer cognition in PD. Eighteen and a half percent of caregivers were found to have MCI, in association with a lower physical and mental QoL. This reflected in lower QoL and mood for the respective PD patients.Conclusion: Impaired cognition and QoL in caregivers was associated with decreased QoL and mood for respective PD patients, suggesting MCI in caregivers is an important consideration for the management of PD.

Auditory hallucinations activate language and verbal short-term memory, but not auditory, brain regions

Auditory verbal hallucinations (AVH, ‘hearing voices’) are an important symptom of schizophrenia but their biological basis is not well understood. One longstanding approach proposes that they are perceptual in nature, specifically that they reflect spontaneous abnormal neuronal activity in the auditory cortex, perhaps with additional ‘top down’ cognitive influences. Functional imaging studies employing the symptom capture technique—where activity when patients experience AVH is compared to times when they do not—have had mixed findings as to whether the auditory cortex is activated. Here, using a novel variant of the symptom capture technique, we show that the experience of AVH does not induce auditory cortex activation, even while real speech does, something that effectively rules out all theories that propose a perceptual component to AVH. Instead, we find that the experience of AVH activates language regions and/or regions that are engaged during verbal short-term memory.

Cybonto: Towards Human Cognitive Digital Twins for Cybersecurity (Preprint)

UNSTRUCTURED Cyber defense is reactive and slow. On average, the time-to-remedy is hundreds of times larger than the time-to-compromise. In response, Digital Twins (DTs) and particularly Human Digital Twins (HDTs) offer the capability of running massive simulations across multiple knowledge domains. Simulated results offer insights into adversaries' behaviors and tactics, resulting in better proactive cyber-defense strategies. For the first time, this paper solidifies the vision of DTs and HDTs for cybersecurity via the Cybonto conceptual framework proposal. The paper also contributes the Cybonto ontology to guide the developments of such HDTs. In particular, the ontology formally documented 108 constructs and thousands of cognitive-related paths based on 20 time-tested psychology theories. Finally, the paper applied 20 network centrality algorithms in ranking the constructs by their cognitive influences. The top 10 constructs call for extensions of current digital cognitive architectures such as: explicitly implementing more refined structures of Long-term Memory and Perception, putting a stronger focus on influential non-cognitive constructs such as Arousal, and creating new capabilities for simulating, reasoning about, and selecting circumstances.

Cybonto: Towards Human Cognitive Digital Twins for Cybersecurity

Cyber defense is reactive and slow. On average, the time-to-remedy is hundreds of times larger than the time-to-compromise. In response, Digital Twins (DTs) and particularly Human Digital Twins (HDTs) offer the capability of running massive simulations across multiple knowledge domains. Simulated results offer insights into adversaries' behaviors and tactics, resulting in better proactive cyber-defense strategies. For the first time, this paper solidifies the vision of DTs and HDTs for cybersecurity via the Cybonto conceptual framework proposal. The paper also contributes the Cybonto ontology to guide the developments of such HDTs. In particular, the ontology formally documented 108 constructs and thousands of cognitive-related paths based on 20 time-tested psychology theories. Finally, the paper applied 20 network centrality algorithms in ranking the constructs by their cognitive influences. The top 10 constructs call for extensions of current digital cognitive architectures such as: explicitly implementing more refined structures of Long-term Memory and Perception, putting a stronger focus on influential non-cognitive constructs such as Arousal, and creating new capabilities for simulating, reasoning about, and selecting circumstances.

Perceived Metalinguistic and Cognitive Influences of Bilingual Education

Despite the substantial body of academic research regarding the metalinguistic and cognitive effects of bilingual education, most of the literature reports on large-scale experimental studies (e.g., Bialystok et al., 2010) while little is known about how individuals who have participated in bilingual programs view their learning outcomes. The objective of this study was to investigate whether there are trends in the self-perceived outcomes of bilingual immersion education on people who have spent at least four years in a bilingual educational setting. Ten individuals who met this criterion were interviewed and the audio recordings of their interviews were transcribed and analyzed inductively to allow themes to emerge from the participants’ words. Findings indicate there were identifiable themes in how participants perceived their education and the amount of time and specific grade levels spent in bilingual programs tended to correspond with certain participant response patterns. This study has implications for the many emerging Georgia dual language immersion programs and their recruitment strategies. Keywordsbilingual education, dual language immersion, metalinguistic ability, cognitive ability

Kindergarten teachers' representations for their socio-cognitive practices during the Natural Sciences activities

The aim of the current paper is to investigate the traces of socio-cognitive influences in kindergarten teachers’ representations about the practices they tend to follow when they develop Natural Sciences activities in kindergarten. A quantitative approach was used, with the research tool being an electronic questionnaire that was completed online by 94 kindergarten teachers served in public Kindergartens. The questionnaire was firstly used in a pilot survey where receiving feedback it was further developed for the main research. Research analysis showed that kindergarten teachers’ representations concerning their teaching choices and actions of their students are characterized by practices that are influenced by the socio-cognitive teaching strategy. These practices are followed from both teachers and their students from moderate to large extent.

Does Vergence Affect Perceived Size?

Since Kepler (1604) and Descartes (1637), it has been suggested that ‘vergence’ (the angular rotation of the eyes) plays a key role in size constancy. However, this has never been tested divorced from confounding cues such as changes in the retinal image. In our experiment, participants viewed a target which grew or shrank in size over 5 s. At the same time, the fixation distance specified by vergence was reduced from 50 to 25 cm. The question was whether this change in vergence affected the participants’ judgements of whether the target grew or shrank in size? We found no evidence of any effect, and therefore no evidence that eye movements affect perceived size. If this is correct, then our finding has three implications. First, perceived size is much more reliant on cognitive influences than previously thought. This is consistent with the argument that visual scale is purely cognitive in nature (Linton, 2017; 2018). Second, it leads us to question whether the vergence modulation of V1 contributes to size constancy. Third, given the interaction between vergence, proprioception, and the retinal image in the Taylor illusion, it leads us to ask whether this cognitive approach could also be applied to multisensory integration.