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2021 ◽  
Author(s):  
◽  
James Hugman

<p>This thesis concerns itself with the depiction of mythical Thebes in extant Greek tragedy, and how this relates to the tragedians’ view of Athens itself. Throughout the Classical Period, Thebes was one of Athens’ biggest enemy poleis, and this complex relationship is often mirrored in the dramas that feature Thebes and Thebans in principal roles. For the purposes of this thesis, I am limiting my scope to dramas that deal with the “Seven Against Thebes” mythic cycle and, to pare the topic down even further, I am only examining those tragedies that feature either Eteocles, Polynices, or both.  Chapter one deals with Aeschylus’ Seven Against Thebes, where I argue that Thebes is not only presented as a positive force, but actually comes to be identified as a stand-in for Athens. The Thebes of Aeschylus’ play shares many common factors with Athens of the early fifth-century B.C.  Chapter two is about Euripides’ Phoenician Women. The main argument here is that Euripides uses his Theban characters as mouthpieces for his own ideas on political rhetoric, particularly political issues that are of importance to contemporary Athens. Additionally, Phoenician Women’s fragmented, episodic plot and its large cast of characters contribute to an image of Thebes as a disorganised, chaotic polis, and one that is the antithesis of Athens. At the same time, its emphasis on the feminine complicates this picture somewhat; although this contributes to the “anti-Athens” image, whether or not this is a positive thing is unclear.  My third and final chapter concerns Sophocles’ Oedipus at Colonus and the lack of consistency in its depiction of Theban characters. Polynices and Creon are characterised negatively, but Oedipus and especially Antigone and Ismene appear in a much more positive light. Furthermore, Theseus appears in the OC as a representative of Athens so, fundamentally, the OC is about the relationship between the two poleis, and an exhortation for Thebes to strive to be more like Athens.  My conclusion is that tragedy’s treatment of Thebes is malleable and that there is not necessarily one standard way of depicting mythical Theban characters. At the same time, I also conclude that, no matter how Thebes is represented, there is always an underlying tension regarding how Thebes relates to Athens; the two cities are in a constant state of comparison and contrast.</p>


2021 ◽  
Author(s):  
◽  
James Hugman

<p>This thesis concerns itself with the depiction of mythical Thebes in extant Greek tragedy, and how this relates to the tragedians’ view of Athens itself. Throughout the Classical Period, Thebes was one of Athens’ biggest enemy poleis, and this complex relationship is often mirrored in the dramas that feature Thebes and Thebans in principal roles. For the purposes of this thesis, I am limiting my scope to dramas that deal with the “Seven Against Thebes” mythic cycle and, to pare the topic down even further, I am only examining those tragedies that feature either Eteocles, Polynices, or both.  Chapter one deals with Aeschylus’ Seven Against Thebes, where I argue that Thebes is not only presented as a positive force, but actually comes to be identified as a stand-in for Athens. The Thebes of Aeschylus’ play shares many common factors with Athens of the early fifth-century B.C.  Chapter two is about Euripides’ Phoenician Women. The main argument here is that Euripides uses his Theban characters as mouthpieces for his own ideas on political rhetoric, particularly political issues that are of importance to contemporary Athens. Additionally, Phoenician Women’s fragmented, episodic plot and its large cast of characters contribute to an image of Thebes as a disorganised, chaotic polis, and one that is the antithesis of Athens. At the same time, its emphasis on the feminine complicates this picture somewhat; although this contributes to the “anti-Athens” image, whether or not this is a positive thing is unclear.  My third and final chapter concerns Sophocles’ Oedipus at Colonus and the lack of consistency in its depiction of Theban characters. Polynices and Creon are characterised negatively, but Oedipus and especially Antigone and Ismene appear in a much more positive light. Furthermore, Theseus appears in the OC as a representative of Athens so, fundamentally, the OC is about the relationship between the two poleis, and an exhortation for Thebes to strive to be more like Athens.  My conclusion is that tragedy’s treatment of Thebes is malleable and that there is not necessarily one standard way of depicting mythical Theban characters. At the same time, I also conclude that, no matter how Thebes is represented, there is always an underlying tension regarding how Thebes relates to Athens; the two cities are in a constant state of comparison and contrast.</p>


Author(s):  
Jian Jin ◽  
Banrida Wahlang ◽  
Monika Thapa ◽  
Kimberly Z. Head ◽  
Josiah E. Hardesty ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Chenglei Zhu ◽  
Kebin Yang ◽  
Guangzhu Li ◽  
Ying Li ◽  
Zhimin Gao

Invertases (INVs) can irreversibly hydrolyze sucrose into fructose and glucose, which play principal roles in carbon metabolism and responses to various stresses in plants. However, little is known about the INV family in bamboos, especially their potential function in drought stress. In this study, 29 PeINVs were identified in moso bamboo (Phyllostachys edulis). They were clustered into alkaline/neutral invertase (NINV) and acid invertase (AINV) groups based on the gene structures, conserved motifs, and phylogenetic analysis results. The collinearity analysis showed nine segmental duplication pairs within PeINVs, and 25 pairs were detected between PeINVs and OsINVs. PeINVs may have undergone strong purification selection during evolution, and a variety of stress and phytohormone-related regulatory elements were found in the promoters of PeINVs. The tissue-specific expression analysis showed that PeINVs were differentially expressed in various moso bamboo tissues, which suggested that they showed functional diversity. Both the RNA-seq and quantitative real-time PCR results indicated that four PeINVs were significantly upregulated under drought stress. Co-expression network and Pearson’s correlation coefficient analyses showed that these PeINVs co-expressed positively with sugar and water transport genes (SWTGs), and the changes were consistent with sugar content. Overall, we speculate that the identified PeINVs are spatiotemporally expressed, which enables them to participate in moso bamboo growth and development. Furthermore, PeINVs, together with SWTGs, also seem to play vital roles in the response to drought stress. These results provide a comprehensive information resource for PeINVs, which will facilitate further study of the molecular mechanism underlying PeINVs involvement in the response to drought stress in moso bamboo.


2021 ◽  
Vol 26 (2) ◽  
pp. 61
Author(s):  
Romaniyanto Romaniyanto ◽  
Cita Rosita Sigit Prakoeswa ◽  
Damayanti Tinduh ◽  
Hari Basuki Notobroto ◽  
Fedik Abdul Rantam ◽  
...  

Low back pain is a crucial public health problem that is commonly associated with intervertebral disc de‐ generation and has vast socio‐economic impact worldwide. Current treatments for disc degeneration are conservative, non‐surgical, or surgical interventions, and there is no current clinical therapy aimed at directly reversing the degeneration. Given the limited capacity of intervertebral disc (IVD) cells to self‐repair, treatment aiming to regenerate IVDs is a topic of interest and mesenchymal stem cells (MSCs) have been identified as having potential in this regeneration. Recent studies have revealed that the benefits of MSC therapy could result from the molecules the cells secrete and that play principal roles in regulating essential biologic processes, rather than from the implanted cells themselves. Therefore, the objective of this study is to review the potential use of the MSC secretome to regenerate IVDs. Current evidence shows that the secretome may regenerate IVDs by modulating the gene expressions of nucleus pulposus cells (upregulation of keratin 19 and downregulation of matrix metalloproteinase 12 and matrix Gla protein) and stimulating IVD progenitor cells to repair the degenerated disc.


Plants ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 36
Author(s):  
Ahmed M. Abd-ElGawad ◽  
Abd El-Nasser G. El Gendy ◽  
Abdulaziz M. Assaeed ◽  
Saud L. Al-Rowaily ◽  
Abdullah S. Alharthi ◽  
...  

Herbicides are natural or synthetic chemicals used to control unwanted plants (weeds). To avoid the harmful effects of synthetic herbicides, considerable effort has been devoted to finding alternative products derived from natural sources. Essential oils (EOs) from aromatic plants are auspicious source of bioherbicides. This review discusses phytotoxic EOs and their chemical compositions as reported from 1972 to 2020. Using chemometric analysis, we attempt to build a structure-activity relationship between phytotoxicity and EO chemical composition. Data analysis reveals that oxygenated terpenes, and mono- and sesquiterpenes, in particular, play principal roles in the phytotoxicity of EOs. Pinene, 1,8 cineole, linalool, and carvacrol are the most effective monoterpenes, with significant phytotoxicity evident in the EOs of many plants. Caryophyllene and its derivatives, including germacrene, spathulenol, and hexahydrofarnesyl acetone, are the most effective sesquiterpenes. EOs rich in iridoids (non-terpene compounds) also exhibit allelopathic activity. Further studies are recommended to evaluate the phytotoxic activity of these compounds in pure forms, determine their activity in the field, evaluate their safety, and assess their modes of action.


Author(s):  
J.F.R. Boddens Hosang

This chapter discusses the role of rules of engagement (ROE) in the context of criminal law and the influence of criminal law on ROE, continuing on to examine the two principal roles ROE can play in the criminal law context: as an accusatory device and as an exculpatory device. Further, it explores the concept of ‘ROE crimes’ and analyses the concept of mens rea in the context of ROE and military operations, with special emphasis on the role of the defence of superior orders in (international) criminal law. The chapter concludes with a discussion of several criminal law cases centred on ROE.


Medicines ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 97 ◽  
Author(s):  
Christina D. Kwon ◽  
Raveena Khanna ◽  
Kyle A. Williams ◽  
Madan M. Kwatra ◽  
Shawn G. Kwatra

Prurigo nodularis (PN) is a chronic inflammatory skin disease characterized oftentimes by symmetrically distributed, severely pruritic nodules. Currently, the pathophysiology of PN remains to be fully elucidated, but emerging evidence suggests that neuroimmune alterations play principal roles in the pathogenesis of PN. There are several associated etiologic factors thought to be associated with PN, including dermatoses, systemic, infectious, psychiatric, and neurologic conditions. We conducted a systematic literature review to evaluate the clinical presentation, diagnosis, and etiologic factors of PN. In this review, we discuss common differential diagnoses of PN and recommend an evidence-based, standardized diagnostic evaluation for those with suspected PN.


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