Sensitive-stage embryo irradiation affects embryonic neuroblasts and adult motor function

Background Cranial radiation therapy for treating childhood malignancies in the central nervous system or accidental radiation exposure may result in neurological side effects in surviving adults. As tissue homeostasis is maintained by stem cells, understanding the effect of radiation on neural stem cells will provide clues for managing the neurological effects. Drosophila embryos were used as a model system whose sensitivity to irradiation-induced cell death changes from the sensitive to resistant stage during development. Objective Drosophila embryos at the radiation-sensitive stage were irradiated at various doses and the radiation sensitivity was tested regarding the appearance of apoptotic cells in the embryos and the embryonic lethality. Cell fates of the neural stem cells called neuroblasts (NBs) and adult motor function after irradiation were also investigated. Result Irradiation of Drosophila embryos at the radiation-sensitive stage resulted in a dose-dependent increase in the number of embryos containing apoptotic cells 75 min after treatment starting at 3 Gy. Embryonic lethality assayed by hatch rate was induced by 1 Gy irradiation, which did not induce cell death. Notably, no apoptosis was detected in NBs up to 2 h after irradiation at doses as high as 40 Gy. At 3 h after irradiation, as low as 3 Gy, the number of NBs marked by Dpn and Klu was decreased by an unidentified mechanism regardless of the cell death status of the embryo. Furthermore, embryonic irradiation at 3 Gy, but not 1 Gy, resulted in locomotor defects in surviving adults. Conclusion Embryonic NBs survived irradiation at doses as high as 40 Gy, while cells in other parts of the embryos underwent apoptosis at doses higher than 3 Gy within 2 h after treatment. Three hours after exposure to a minimum dose of 3 Gy, the number of NBs marked by Dpn and Klu decreased, and the surviving adults exhibited defects in locomotor ability.

Efficacy of Thai indigenous entomopathogenic nematodes for controlling fall armyworm (Spodoptera frugiperda) (J. E. Smith)(Lepidoptera; Noctuidae)

Background Under laboratory and greenhouse conditions, the virulence of 2 isolates of Thai indigenous entomopathogenic nematodes (EPNs) in controlling the fall armyworm (FAW), Spodoptera frugiperda (J. E. Smith) (Lepidoptera; Noctuidae), was demonstrated. Six EPNs dosages were tested against 2 larval instars of FAW under the laboratory conditions, while 2 different concentrations were tested under the greenhouse conditions. Results The results of a laboratory experiment revealed that 2 Thai indigenous EPNs isolates (Heterorhabditis indica isolate AUT 13.2 and Steinernema siamkayai isolate APL 12.3) were efficient against the FAW, 2nd and 5th larval instars. Six different nematode concentrations (50,100, 150, 200, 250 and 300 infectious juveniles (IJs) ml−1) were evaluated, and all were proven to be effective, with the mortality rate associated with concentration. Inoculated larvae in the 2nd instar was more vulnerable than that in the 5th instar. H. indica isolate AUT 13.2 was more destructive than S. siamkayai isolate APL 12.3. The greatest mortality rate of 2nd instar larvae was 83% when H. indica AUT 13.2 was applied at the concentration of 250 IJs ml−1, and 68% when the nematode S. siamkayai APL 12.3 was used at the concentration of 300 IJs ml−1. At 250 IJsml−1, the highest mortality rate of the 5th instar larvae was 45% for H. indica AUT 13.2 and 33% for S. siamkayai APL 12.3, respectively. To customize the concentration and volume of nematodes suspension evaluated in the greenhouse settings, the most sensitive stage of FAW and the optimum concentration that caused the highest mortality were used. The concentrations of both indigenous nematodes’ isolates were 20,000 and 50,000 IJsml−1 per pot, respectively, and the results showed that the mortality rates were lower than that in the laboratory. FAW mortality rate was the highest (58%) in case of the nematode H. indica isolate AUT 13.2, against (45%) in case of S. siamkayai isolate APL 12.3, at the 50,000 IJs ml−1 concentrations. Conclusions The study revealed the 2 Thai indigenous EPNs isolates (H. indica isolate AUT 13.2 and S. siamkayai isolate APL 12.3) were capable of controlling the FAW in both laboratory and greenhouse environments. The 2 Thai EPNs showed the potential to be considered as a biological control agent.

Using a Blur Metric to Estimate Linear Motion Blur Parameters

Motion blur is a common artifact in image processing, specifically in e-health services, which is caused by the motion of a camera or scene. In linear motion cases, the blur kernel, i.e., the function that simulates the linear motion blur process, depends on the length and direction of blur, called linear motion blur parameters. The estimation of blur parameters is a vital and sensitive stage in the process of reconstructing a sharp version of a motion blurred image, i.e., image deblurring. The estimation of blur parameters can also be used in e-health services. Since medical images may be blurry, this method can be used to estimate the blur parameters and then take an action to enhance the image. In this paper, some methods are proposed for estimating the linear motion blur parameters based on the extraction of features from the given single blurred image. The motion blur direction is estimated using the Radon transform of the spectrum of the blurred image. To estimate the motion blur length, the relation between a blur metric, called NIDCT (Noise-Immune Discrete Cosine Transform-based), and the motion blur length is applied. Experiments performed in this study showed that the NIDCT blur metric and the blur length have a monotonic relation. Indeed, an increase in blur length leads to increase in the blurriness value estimated via the NIDCT blur metric. This relation is applied to estimate the motion blur. The efficiency of the proposed method is demonstrated by performing some quantitative and qualitative experiments.

Super-Resolution Model Quantized in Multi-Precision

Deep learning has achieved outstanding results in various tasks in machine learning under the background of rapid increase in equipment’s computing capacity. However, while achieving higher performance and effects, model size is larger, training and inference time longer, the memory and storage occupancy increasing, the computing efficiency shrinking, and the energy consumption augmenting. Consequently, it’s difficult to let these models run on edge devices such as micro and mobile devices. Model compression technology is gradually emerging and researched, for instance, model quantization. Quantization aware training can take more accuracy loss resulting from data mapping in model training into account, which clamps and approximates the data when updating parameters, and introduces quantization errors into the model loss function. In quantization, we found that some stages of the two super-resolution model networks, SRGAN and ESRGAN, showed sensitivity to quantization, which greatly reduced the performance. Therefore, we use higher-bits integer quantization for the sensitive stage, and train the model together in quantization aware training. Although model size was sacrificed a little, the accuracy approaching the original model was achieved. The ESRGAN model was still reduced by nearly 67.14% and SRGAN model was reduced by nearly 68.48%, and the inference time was reduced by nearly 30.48% and 39.85% respectively. What’s more, the PI values of SRGAN and ESRGAN are 2.1049 and 2.2075 respectively.

Challenges of Water Sensitive Cities in Mexico: The Case of the Metropolitan Area of Guadalajara

Mexico is currently facing important water management challenges. Cities in the country are facing water scarcity and at the same time they struggle with floods during the raining season. The water sensitive urban design (WSUD) approach has proved to be helpful around the world in tackling urban water challenges such as floods or water scarcity. The WSUD approach highlights the role of both the water cycle and the water utilities systems, when transitioning towards a water sensitive stage. Therefore, the objective of this research is to demonstrate the relevance for cities of a WSUD approach by analyzing the current situation of the water cycle and the water utility in the Metropolitan Area of Guadalajara (MAG). This research proposes a case study approach. Within our case of study, we focused on the water cycle and the water utilities system (Sistema Intermunicipal de los Servicios de Agua Potable y Alcantarillado (SIAPA)) and ask two questions: (1) What are the causes of water scarcity and flooding in the MAG? and (2) What are the proposals to solve these problems under a WSUD approach? By answering these questions, we identified that the water management in the MAG corresponds to a single purpose infrastructure. This type of water management is common in developing cities and does not contribute to solve the problems of water scarcity and floods. The water supply policy is based only on the construction of large dams disregarding the storage and use of rainwater, and reuse of greywater, and water-conservation devices. In order to transition towards a water sensitive stage, changes in the water policy need to take place and a WSUD approach that includes multi-purpose infrastructure, should be considered.

Challenges of Water Sensitive Cities in México: The case of the Metropolitan Zone of Guadalajara.

Mexico is currently facing important water management challenges. Cities in the country are facing water scarcity and at the same time, they struggle with floods during the raining season. The water sensitive urban design (WSUD) approach has proved to be helpful in tackling urban water challenges such as floods and water scarcity and it is being implemented in cities around the world. The WSUD approach highlights the role of both the water cycle and the water utilities systems, when transitioning towards a water sensitive stage. Therefore, the objective of this research is to analyse the current situation of the water cycle and the water utility (SIAPA). To do so, we have selected the Metropolitan Area of Guadalajara (MAG) and proposes a case study approach. Within our case of study, we answer two questions: 1) What are the causes of water scarcity and flooding in the MAG? and 2) What are the proposals to solve these problems under a WSUD approach? By answering these questions, we identified that the water management in the MAG corresponds to a single purpose infrastructure. This type of management does not contribute to solve the problems of water scarcity and floods. The water supply policy is based only on the construction of large dams disregarding the storage and use of rainwater, and reuse of greywater, and water-conservation devices. In order to transition towards a water sensitive stage, a WSUD approach that includes multi-purpose infrastructure should be considered. Such as green roofs, swales, rainwater gardens, infiltration trenches, etc.

Priming seeds-method for increasing the germination of soybean seeds under drought stress conditions

Drought is one of the most important factors limiting the successful production of cultivated plants. One of the most sensitive stage to the water deficit in plants is seed germination. There are various methods of pre-sowing treatments that aim to reduce the negative impact of drought stress and improve seed germination. One of them is priming seeds. The aim of this experiment was to examine the effect of priming seeds in solutions - KNO3 (1%), ascorbic acid - AsA (100 mgl-1) and potassium chloride KCl (1%) on the reduction of the negative effect of drought stress. The effect of drought stress was simulated using different concentrations of PEG 6000 (0 (control), -0.30, -0.51, -0.80 MPa). The results of the research showed that with the increase of water deficiency, the effect of priming seeds is greater. At the water potential of the solution of -0.30 MPa, germination energy and seed germination increased on average by 6.77% and 5.08%, while at the water potential of the solution of -0.80 MPa, the increase was 19.28% and 16.75%, respectively. Also, priming seeds significantly reduced the intensity of lipid peroxidation and the content of free proline. From all the above, it can be concluded that priming of seeds is a method that can serve to improve the germination of soybean seeds in conditions of drought stress.

ڕەنگدانەوەی نووسینەوەی مێژوویی لە گۆڤاری گەلاوێژدا

Reflection of Historical Writing in Galawezh Magazine The study aims at highlighting the importance of Galawezh magazine, which was issued during 1939-1949, in the process of historical writing, with its ten years of historical inventory in the fields of (Kurds and Kurdistan history, Second World War, the press history, developments and internal events in Iraq, etc).This magazine was characterized by an active presence in following up the historical material and political developments at a sensitive stage in the history of the Kurds, Iraq, and the world. Building on this, the research is divided into two sections: the first one deals with the historical development of Galawezh magazine through its objectives, form and contents, meanwhile the second one is dedicated to the role of the magazine in historical writing through the most important fields that the magazine worked for and how to deal with historical topics. Finally, the researcher has come up with a number of conclusions, mainly: The historical subjects occupied a high proportion in the magazine writings, especially in the field of history of the Kurds, which in turn contributed to the development of the historical writing movement in Kurdistan. The magazine also followed the rapid political developments witnessed by Iraq and the world.