Dual-Energy Computed Tomography Imaging in Early-Stage Hepatocellular Carcinoma: A Preliminary Study

Background. This study aims to evaluate the application of dual-energy computed tomography (DECT) for multiparameter quantitative measurement in early-stage hepatocellular carcinoma (HCC). Methods. The study retrospectively enrolled 30 patients with early-stage HCC and 43 patients with early-stage HCC who received radiofrequency ablation (RFA) and underwent abdomen enhanced CT scans in GSI mode. The GSI viewer was used for image display and data analysis. The regions of interest (ROIs) were delineated in the arterial phase and the venous phase. The optimal single energy value, CT values on different energy levels (40 keV, 70 keV, 100 keV, and 140 keV), the optimal energy level, the slope of the spectral attenuation curve, the effective atomic number (Zeff), iodine concentration (IC), water concentration (WC), normalized iodine concentration (NIC), and normalized water concentration (NWC) are measured and quantitatively analyzed. Results. The CT values of early-stage HCC at different single energy levels in dual phases were significantly different, and the single energy values were negatively correlated with the CT values. In the arterial phase and the venous phase, the optimal energy values for the best contrast-to-noise ratio were (68.34 ± 3.20) keV and (70.14 ± 2.01) keV, respectively. The slope of the spectral attenuation curve showed a downward trend at 40 keV, 70 keV, 100 keV, and 140 keV, but there was no statistically significant difference P > 0.05 . Zeff was positively correlated with IC and standardized IC, but has no significant correlation with WC and NWC in dual phases. Conclusion. DECT imaging contains multiparameter information and has different application values for early-stage HCC, and it is necessary to select the parameters reasonably for personalized and comprehensive evaluation.

The Degree of Linear Polarization for Suspended Particle Fields from Diverse Natural Waters

The Degree of Linear Polarization (DoLP) for unperturbed particle fields in waters from six diverse regions around the globe was measured with the custom Multi-Angle Scattering Optical Tool (MASCOT). DoLP here is defined as the ratio of two elements of Mueller scattering matrix, i.e., -M12/M11. Field sites covered inland waters, coastal oceans and open oceans, including both ocean color Case I and II water types. The angular shape of the measured particulate DoLP was analyzed in detail for each field site and for the ensemble average. Three parameters used to quantitatively characterize DoLP shape were the symmetry with respect to 90°, peak magnitude, and peak angle of measured DoLP angular curve. Vertical profiles of particulate DoLP were analyzed with maximum recorded depth of 111 m. Converse to Rayleigh scatterers, we found measured particulate DoLPs were not symmetric with respect to 90°. On average, DoLP peaks were shifted slightly toward larger angles, with most falling between estimated values of 90° and 95°. All particulate DoLP peak magnitudes generally varied within [0.6, 0.9]. Lorenz-Mie (homogeneous sphere) light scattering theory was used to construct a new inversion for bulk particulate refractive index from a lookup table based on DoLP and spectral attenuation measurements. We compared the Mie-DoLP-based particulate refractive index retrieval with the backscattering-based model from (Twardowski et al., J. Geophys. Res., 2001, 106(C7), 14,129–14,142). Particulate refractive index retrieved with the two models were in some cases comparable. At two of the six field sites we saw good agreement between the two models, whereas at another two field sites we observed large discrepancies between the two models. Further investigation on the choice of the modeled particle shapes and compositions may improve this retrieval approach. Results are compatible with previous studies on DoLPs in natural waters and comprehensive observations are provided on the particulate DoLP angular shape, vertical profile and global distributions that are important for future vector radiative transfer simulations. This study is relevant to future PACE polarimeters and associated remote retrieval of oceanic particle composition using polarimetry.

Local and regional P-wave spectral attenuation model for Iran

SUMMARY A robust frequency-dependent local and regional P-wave attenuation model is estimated for continental paths in the Iranian Plateau. In order to calculate the average attenuation parameters, 46 337 vertical-component waveforms related to 9267 earthquakes, which are recorded at the Iranian Seismological Center (IRSC) stations, have been selected in the distance range 10–1000 km. The majority of the event's magnitudes are less than 4.5. This collection of records provides high spatial ray path coverage. Results indicate that the shape of attenuation P-wave curve versus distance is not uniform and has three distinct sections with hinges at 90 and 175 km. A trilinear model for attenuation of P-wave amplitude in the frequency range 1–10 Hz is proposed in this study. Fourier spectral amplitudes are found to decay as R−1.2 (where R is hypocentral distance), corresponding to geometric spreading within 90 km from the source. There is a section from 90 to 175 km, where the attenuation is described as R0.8, and the attenuation is described well beyond 175 km by R−1.3. Moreover, the average quality factor for Pg and Pn waves (QPg and QPn), related to anelastic attenuation is obtained as Qpg= (54.2 ± 2.6)f(1.0096±0.07) and Qpn= (306.8 ± 7.4)f (0.51±0.05). There is a good agreement between the results of the model and observations. Also, the attenuation model shows compatibility with the recent regional studies. From the results it turns out that the amplitude of P waves attenuates more rapidly in comparison with the global models in local distances.

Spectral attenuation of ocean waves in pack ice and its application in calibrating viscoelastic wave-in-ice models

We investigate a case of ocean waves through a pack ice cover captured by Sentinel-1A synthetic aperture radar (SAR) on 12 October 2015 in the Beaufort Sea. The study domain is 400 km by 300 km, adjacent to a marginal ice zone (MIZ). The wave spectra in this domain were reported in a previous study (Stopa et al., 2018b). In that study, the authors divided the domain into two regions delineated by the first appearance of leads (FAL) and reported a clear change of wave attenuation of the total energy between the two regions. In the present study, we use the same dataset to study the spectral attenuation in the domain. According to the quality of SAR-retrieved wave spectrum, we focus on a range of wave numbers corresponding to 9–15 s waves from the open-water dispersion relation. We first determine the apparent attenuation rates of each wave number by pairing the wave spectra from different locations. These attenuation rates slightly increase with increasing wave number before the FAL and become lower and more uniform against wave number in thicker ice after the FAL. The spectral attenuation due to the ice effect is then extracted from the measured apparent attenuation and used to calibrate two viscoelastic wave-in-ice models. For the Wang and Shen (2010b) model, the calibrated equivalent shear modulus and viscosity of the pack ice are roughly 1 order of magnitude greater than that in grease and pancake ice reported in Cheng et al. (2017). These parameters obtained for the extended Fox and Squire model are much greater, as found in Mosig et al. (2015) using data from the Antarctic MIZ. This study shows a promising way of using remote-sensing data with large spatial coverage to conduct model calibration for various types of ice cover.Highlights. Three key points: The spatial distribution of wave number and spectral attenuation in pack ice are analyzed from SAR-retrieved surface wave spectra. The spectral attenuation rate of 9–15 s waves varies around 10−5 m2 s−1, with lower values in thicker semicontinuous ice fields with leads. The calibrated viscoelastic parameters are greater than those found in pancake ice.

Measuring and Monte Carlo Modelling of X-Ray and Gamma-Ray Attenuation in Personal Radiation Shielding Protective Clothing

A collection of personal protective equipment (PPE), suitable for use in case of accident in nuclear facilities or radiological emergencies, was gathered at the National Institute for Nuclear, Chemical and Biological Protection, Czech Republic. The shielding characteristics of the various PPE materials were measured via narrow geometry spectral attenuation measurements with point radionuclide sources covering a broad range of photon energies. Photon relative penetration and attenuation for relevant energies of the spectra were the principal experimentally determined quantities for tested PPE. Monte Carlo simulations in the MCNPX™ code were carried out to determine photon attenuation for respective energies in the tested PPE, and the results were compared to those determined experimentally. Energy depositions in a unit volume of an ORNL phantom were simulated in a radioactive aerosols atmospheric environment to determine effective doses both for the whole body and in various organs in the human torso during exposure to different dispersed radioactive aerosols while wearing one of the PPE protecting against X- and gamma-ray. This work aimed to determine the effective dose and its decrease for individual PPE protecting against X- and gamma-ray.