Signaling Potential Therapeutic Herbal Medicine Prescription for Treating COVID-19 by Collaborative Filtering

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has aggressed in more than 200 countries and territories since Dec 2019, and 30 million cases of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 have been reported, including 950,000 deaths. Supportive treatment remains the mainstay of therapy for COVID-19. There are no small-molecule–specific antiviral drugs available to prevent and treat COVID-19 until recently. Herbal medicine can facilitate syndrome differentiation and treatment according to the clinical manifestations of patients and has demonstrated effectiveness in epidemic prevention and control. The National Health Commission (NHC) of China has recommended “three TCM prescriptions and three medicines,” as a group of six effective herbal formulas against COVID-19 in the released official file “Diagnosis and Treatment Protocol for COVID-19 Patients: Herbal Medicine for the Priority Treatment of COVID-19.” This study aimed to develop a collaborative filtering approach to signaling drug combinations that are similar to the six herbal formulas as potential therapeutic treatments for treating COVID-19. The results have been evaluated by herbal medicine experts’ domain knowledge.

Professor Xiaofeng’s Zhang Experience in Treating Postpartum Body Pain

Postpartum physical pain is common in clinic, mostly manifested in pain, numbness or weight, swelling and so on of limbs and joints during puerperium, and some of them fail to heal over the years, becoming stubborn “puerperal fever.” Mr. Zhang has been a doctor for more than 30 years. He has superb medical skills and has unique opinions on postpartum diseases. The author is lucky to follow-up. Now, his experience in syndrome differentiation and treatment of postpartum body pain is analyzed as follows, and the tested case is attached.

Progress in Traditional Chinese Medicine Against Respiratory Viruses: A Review

Respiratory viruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV)-1, SARS-CoV-2, influenza A viruses, and respiratory syncytial virus, pose a serious threat to society. Based on the guiding principles of “holism” and “syndrome differentiation and treatment”, traditional Chinese medicine (TCM) has unique advantages in the treatment of respiratory virus diseases owing to the synergistic effect of multiple components and targets, which prevents drug resistance from arising. According to TCM theory, there are two main strategies in antiviral treatments, namely “dispelling evil” and “fu zheng”. Dispelling evil corresponds to the direct inhibition of virus growth and fu zheng corresponds to immune regulation, inflammation control, and tissue protection in the host. In this review, current progress in using TCMs against respiratory viruses is summarized according to modern biological theories. The prospects for developing TCMs against respiratory viruses is discussed to provide a reference for the research and development of innovative TCMs with multiple components, multiple targets, and low toxicity.

Experience of 4 Cases of Treatment of Gynecomastia from Dialectical Analysis of Liver and Kidney

The author adopts the method of syndrome differentiation and treatment in Chinese medicine based on the treatment of 4 cases of gynecomastia from dialectical analysis of liver and kidney. The report is as follows.

Research Progress of Treating Diabetic Nephropathy with Traditional Chinese Medicine

By collecting and sorting out the literature and journals on the clinical use of Chinese medicine in the treatment of diabetic nephropathy in recent years, it is concluded that Chinese medicine is effective in the treatment of DKD. Chinese medicine therapy has a unique role in the treatment of diabetic nephropathy. How to correct syndrome differentiation and treatment? Improving clinical effects is the research direction that all medical staff will work together in the future.

Professor Ruixia Pei’s Experience in Treating Hyperthyroidism

In this article, we summarize the clinical experience of Professor Ruixia Pei, a famous traditional Chinese medicine practitioner in Shaanxi Province, China, in treating hyperthyroidism. The etiology and pathogenesis, syndrome differentiation, and medication experience are introduced in detail. This paper summarizes the advantages of Professor Pei’s methods of syndrome differentiation and treatment of hyperthyroidism. This may help enrich the clinical treatment of hyperthyroidism, and provide some diagnosis and treatment ideas.

Analysis on the Law of Chinese Medicine Use of Ulcerative Colitis and TCM Syndrome Differentiation and Treatment

Ulcerative colitis is a kind of inflammatory bowel disease. The disease is slow and easy to relapse. Western medicine treatment mainly focuses on symptomatic treatment, which has certain side effects on liver and kidney function. Ulcerative colitis has unique advantages in disease, so by studying a large amount of information, mainly from the law of traditional Chinese medicine use of UC, and a brief summary of the treatment of TCM syndromes, this article provides ideas and basis for clinical diagnosis and treatment of the disease.

Research Progress of TCM Treatment of Uterine Fibroids

Uterine fibroids are the most common benign tumors in gynecology. Traditional Chinese medicine treats uterine fibroids according to syndrome differentiation and treatment. The treatment of uterine fibroids has the characteristics of definitive curative effects and minor side-effects, but there are also many shortcomings, which require more in-depth research and exploration.