Review on the implication on the control of transboundary and trade barrier animal diseases in Ethiopia

Transboundary Animal Diseases (TADs) are highly contagious diseases of livestock within the world. they need importance within the international trade of animals and animal products. With rapidly increasing globalization, associated risk of transboundary disease is emerging. They reduce production and productivity, disrupt local and national economies, and also threaten human health (zoonosis). Transboundary diseases are a priority globally, cumulative effort is required at the international level to attenuate the spread of infectious diseases across the borders. except for sub-Saharan African countries more particularly, eradication of most Transboundary animal diseases is impossible thanks to various technical, financial and logistical reasons like increased outbreaks of transboundary animal diseases droughts and market issues. In Ethiopia Transboundary animal diseases are endemic livestock diseases that cause market limits. This imposes far-reaching challenges for agricultural scientists on the critically important have to improve technologies in animal production and health so as to confirm food security, poverty alleviation and to assist the economic process. The international approach to the management of TADs is predicated on the belief that the majority is often eradicated. However, in developing countries, eradication of most TADs is difficult for a range of technical, financial and logistical reasons. General TADs combating strategies include prevention, early warning, early detection and early control.

Governance structure affects transboundary disease management under alternative objectives

Background The development of public health policy is inextricably linked with governance structure. In our increasingly globalized world, human migration and infectious diseases often span multiple administrative jurisdictions that might have different systems of government and divergent management objectives. However, few studies have considered how the allocation of regulatory authority among jurisdictions can affect disease management outcomes. Methods Here we evaluate the relative merits of decentralized and centralized management by developing and numerically analyzing a two-jurisdiction SIRS model that explicitly incorporates migration. In our model, managers choose between vaccination, isolation, medication, border closure, and a travel ban on infected individuals while aiming to minimize either the number of cases or the number of deaths. Results We consider a variety of scenarios and show how optimal strategies differ for decentralized and centralized management levels. We demonstrate that policies formed in the best interest of individual jurisdictions may not achieve global objectives, and identify situations where locally applied interventions can lead to an overall increase in the numbers of cases and deaths. Conclusions Our approach underscores the importance of tailoring disease management plans to existing regulatory structures as part of an evidence-based decision framework. Most importantly, we demonstrate that there needs to be a greater consideration of the degree to which governance structure impacts disease outcomes.

Molecular Epidemiology of First Lumpy Skin Disease Outbreak in Odisha, India

Lumpy skin disease virus (LSDV) is the causative agent of lumpy skin disease (LSD) which is a member of Capripoxvirus. It is an economically critical transboundary disease affecting cattle. This study records the first LSD incidence in cattle of Ganjam district and analyses data from LSD outbreak in August 2020 on epidemiological and genetic characterization. Out of 452 animals clinically examined (59 farms), 63 animals were clinically affected with LSD, with a total morbidity rate of 13.93%. The morbidity rates in the villages (ten villages) varied from 5.55 to 21.62%. The multivariable logistic regression showed that grazing of animals (P=0.023; OR: 1.90; 95% CI: 1.09-3.32), and lactation and pregnancy status of animals (P=0.007; OR: 2.86; 95% CI: 1.32-6.17) were the potential risk factors for the occurrence of lumpy skin disease. Out of 53 clinically suspected animals collected from Ganjam district of Odisha, 18 samples (33.96%) were found positive by PCR for both P32 and F genes of capripox virus. Phylogenetic analysis of P32 gene of LSD (MW147486) showed 100% similarity with other isolates from India, Bangladesh, Egypt and Saudi Arabia. Additionally, phylogenetic analysis of F gene of LSD (MW147485) revealed a similarity of 97.99 %, 97.36%, and 96.60% with, Odisha India (MT074110), Beni Suif Egypt (MN694826) and Marsa Matrouh Egypt (MN699855), respectively.

OIE and FAO join forces to counter ASF

African swine fever (ASF) is an infectious disease of domestic and wild pigs, which went beyond its natural range (African continent) in the XXI century and since 2007 (emergence in Georgia) has spread to many European and Asia-Pacific countries. According to the immediate notifications and follow-up reports, by early 2021 Europe accounted for about 68% of globally reported outbreaks. However, the greatest losses in the pig industry were inflicted by the outbreak recorded in Asia in 2020, when 6,733,791 animals died that accounted to 82% of the total global losses due to ASF. Just after several years of the current ASF epizootic, without any vaccine or treatment available, it became clear that major problems for the pig industry (mostly for small farmers) as well as destabilization of the global market of pig products were unavoidable. In this regard, in 2014 (Bern, September 2014) a regional standing group of experts on African swine fever (SGE ASF) was established under FAO/OIE GF-TADs umbrella. The aim of the group is to foster closer collaboration between the affected countries, increase transparency and share experience in prevention and control. The work of the permanent expert ASF missions under the GF-TADs umbrella has proven effective and become a model for other regions. A similar group was established in Asia in April 2019 to counter rapid spread of the disease in the Asia-Pacific region, where more than 60% of the world’s pig population is concentrated, and a new permanent ASF expert group for the Americas is being considered. The many-year efforts resulted in the establishment of the FAO/OIE/GF-TADs platform as a progressive mechanism to combat such transboundary disease as African swine fever.

First molecular and serological detection of Epizootic Hemorrhagic Disease virus in white tailed deer ( Odocoileus virginianus ) from Tamaulipas, Mexico

ABSTRACT Epizootic hemorrhagic disease viruses (EHDV) are dsRNA arboviruses transmitted by biting midges of the genus Culicoides that cause disease in domestic and wild ruminants. Epizootic hemorrhagic disease (EHD) is considered the most important infectious disease of white tailed deer (WTD) in North America, some studies in Northeast Mexico reported EHDV-seropositive WTD and EHDV-infected Culicoides vectors. The increasing population of WTD that share habitat with livestock in Northeast México highlights the importance of EHD for the livestock industry in the transboundary region with the U.S. One hundred and twenty two samples from WTD in Tamaulipas state, Mexico were tested by ELISA and RT-PCR for EHDV antibodies and nucleic acid, respectively. Twelve animals were seropositive to ELISA and eleven animals were positive by RT-PCR. This is the first report of EHDV nucleic acid detection in WTD from Mexico. It is hypothesized that applying the transboundary disease approach to interdisciplinary research will help fill knowledge gaps, which could help develop countermeasures to mitigate the threat of EHDV infection in wildlife and livestock along the U.S.-Mexico border.

Cost distribution of bluetongue surveillance and vaccination programmes in Austria and Switzerland (2007–2016)

Bluetongue virus (BTV) is an emerging transboundary disease in Europe, which can cause significant production losses among ruminants. The analysis presented here assessed the costs of BTV surveillance and vaccination programmes in Austria and Switzerland between 2007 and 2016. Costs were compared with respect to time, type of programme, geographical area and who was responsible for payment. The total costs of the BTV vaccination and surveillance programmes in Austria amounted to €23.6 million, whereas total costs in Switzerland were €18.3 million. Our analysis demonstrates that the costs differed between years and geographical areas, both within and between the two countries. Average surveillance costs per animal amounted to approximately €3.20 in Austria compared with €1.30 in Switzerland, whereas the average vaccination costs per animal were €6.20 in Austria and €7.40 in Switzerland. The comparability of the surveillance costs is somewhat limited, however, due to differences in each nation’s surveillance (and sampling) strategy. Given the importance of the export market for cattle production, investments in such programmes are more justified for Austria than for Switzerland. The aim of the retrospective assessment presented here is to assist veterinary authorities in planning and implementing cost-effective and efficient control strategies for emerging livestock diseases.

SERO-SURVEILLANCE OF “PESTE DES PETITS RUMINANTS” PPR IN MONGOLIA AND DEVELOPMENT OF RECOMMENDATION

PPR (Peste des Petits Ruminants) is a transboundary disease, listed in the OIE Terrestrial Animal Health Code, which Mongolia and other countries are obligated to report the disease to the OIE according to the criteria [1]. Purpose of this study is to conduct sero-epidemiological survey for detection of PPR antibody in livestock and susceptible animals from aimag, soums near border area because 244 outbreaks have been recorded [2] in China mainland since September, 2013. A total of 1950 goat and sheep serum samples from 52 soums of 15 aimags have been examined by “ID VET” Competitive ELISA kit for antibody detection. Result showed that PPR virus antibodies have been found in 12 samples from 1550 sheep, and 4 samples from 400 goat samples which have been examined. The same result has been shown after the re-testing the positive samples by ELISA with the serum titration of 1:4 and 1:8. PPR Global strategy for prevention, control and eradication of PPR by 2030, has been developed by OIE and FAO [14]. PPR recommendation has been developed in accordance with the Global strategy and sero-surveillance conducted in Mongolia.