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2022 ◽  
Vol 54 (9) ◽  
pp. 1-35
Author(s):  
Ismaeel Al Ridhawi ◽  
Ouns Bouachir ◽  
Moayad Aloqaily ◽  
Azzedine Boukerche

Internet of Things (IoT) systems have advanced greatly in the past few years, especially with the support of Machine Learning (ML) and Artificial Intelligence (AI) solutions. Numerous AI-supported IoT devices are playing a significant role in providing complex and user-specific smart city services. Given the multitude of heterogeneous wireless networks, the plethora of computer and storage architectures and paradigms, and the abundance of mobile and vehicular IoT devices, true smart city experiences are only attainable through a cooperative intelligent and secure IoT framework. This article provides an extensive study on different cooperative systems and envisions a cooperative solution that supports the integration and collaboration among both centralized and distributed systems, in which intelligent AI-supported IoT devices such as smart UAVs provide support in the data collection, processing and service provisioning process. Moreover, secure and collaborative decentralized solutions such as Blockchain are considered in the service provisioning process to enable enhanced privacy and authentication features for IoT applications. As such, user-specific complex services and applications within smart city environments will be delivered and made available in a timely, secure, and efficient manner.


Author(s):  
Varvara O. Bakumenko ◽  
◽  
Ekaterina G. Ershova ◽  
◽  

In this work we present the results of spore and pollen analysis of forest soils from the Zvenigorod biological station of Moscow State University (Moscow Region, Russia). A comparative analysis of forest soils formed on the site of historical fields of the XVIII–XIX centuries and beyond showed that a specific complex of pollen and spores remains in the residual arable horizons, characteristic only of soils that have passed through the stages of plowing and fallow. It includes pollen from cultivated cereals and arable weeds (buckwheat, cornflower blue), spores of the mace-shaped plaunus (Lycopodium clavatum), as well as spores of the mosses Riccia glauca and Anthoceros spp. The latter are exclusive indicators of fallows, since they are practically not found in other habitats. The identified pollen indicators can be used in landscape and archaeological research to interpret the data of spore-pollen analysis of cultural layers, buried soils, gully-ravine sediments. They can also be used to define the boundaries of ancient fields under modern vegetation.


2021 ◽  
Vol 27 ◽  
Author(s):  
Jonathan Koslowsky ◽  
Amit Kakkar ◽  
Robert T Faillace ◽  
Seth I. Sokol

: Pulmonary embolism (PE) is the third leading cause of cardiovascular mortality. Patients with PE can present with a wide array of symptoms, ranging from mild to life threatening. The mainstay of PE treatment is anticoagulation; however, there are many advanced options available for more severe patients, including catheter-directed interventions, surgical treatments, and hemodynamic support. Although different risk scores and clinical guidelines exist, the primary treating teams are frequently left uncertain on the most suitable treatment for a specific complex patient. Pulmonary Embolism Response Teams (PERT), composed of multidisciplinary experts, have emerged and been implemented in many centers and are available 24 hours a day to help guide the primary team. PERTs have changed the way complex PE patients are managed. In centers with a PERT, teams are called upon very frequently and there is a significant increase in the use of advanced treatments for PE, although there are differences between centers based upon the center's specific PERT protocol and available capabilities. As PE is an evolving area, and more studies are necessary, PERTs around the world can help advance the field and improve the treatment offered to PE patients.


Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6694
Author(s):  
Niamat Khan ◽  
Sidra Shahid ◽  
Abdul R. Asif

Chromatin is a dynamic structure comprising of DNA and proteins. Its unique nature not only help to pack the DNA tightly within the cell but also is pivotal in regulating gene expression DNA replication. Furthermore it also protects the DNA from being damaged. Various proteins are involved in making a specific complex within a chromatin and the knowledge about these interacting partners is helpful to enhance our understanding about the pathophysiology of various chromatin associated diseases. Moreover, it could also help us to identify new drug targets and design more effective remedies. Due to the existence of chromatin in different forms under various physiological conditions it is hard to develop a single strategy to study chromatin associated proteins under all conditions. In our current review, we tried to provide an overview and comparative analysis of the strategies currently adopted to capture the DNA bounded protein complexes and their mass spectrometric identification and quantification. Precise information about the protein partners and their function in the DNA-protein complexes is crucial to design new and more effective therapeutic molecules against chromatin associated diseases.


2021 ◽  
Vol 11 (21) ◽  
pp. 10218
Author(s):  
Eduard Kurz ◽  
Stephan Schulze ◽  
Matti Panian ◽  
Richard Brill ◽  
Karl-Stefan Delank ◽  
...  

The aim of this investigation was to quantify the acute effects of the execution of the physical performance tests within the ice hockey-specific complex test (IHCT) on shooting performance. Thirty-four professional male ice hockey players with an average of 6.9 years of playing experience were recruited. The slap shot (SS) was found to accelerate the puck with a higher speed and greater precision. After the IHCT, the maximum puck speed of successful goal shots decreased considerably (p < 0.001, d > 1.5). The puck speed percentage decrement after the IHCT did not differ between the SS (6.1, SD = 4.4, −5.5–17.9) and the wrist shot (WS, 6.0, SD = 3.5, −0.9–12.2, p = 0.86, d = 0.03). The magnitude of puck speed reduction in the WS was inversely related to the functional heart rate reserve (r = −0.44, p = 0.02) and the blood lactate elimination rate (r = −0.43, p < 0.02). The linear and COD speed tests on-ice resulted in a higher amount of successful goal shots. These findings highlight the interaction of intense on-ice testing and goal-shooting performance.


2021 ◽  
Vol 121 ◽  
pp. 111493
Author(s):  
Dominique Guichaoua ◽  
Ihor Syvorotka ◽  
Ivan Solskii ◽  
Natalia Syvorotka ◽  
Karolina Waszkowska ◽  
...  

2021 ◽  
Vol 3 (3) ◽  
pp. 28-38
Author(s):  
M. V. Cherkunova

The article explores the phenomenon of semantic compression in small format metatexts within the contemporary English scientific discourse. Abstracts to scientific articles from international citation databases, in particular those of Scopus and Web of Science, are analysed with the aim of eliciting ways of semantic compression. The latter is viewed as a key parameter of a scientific abstract, whose semantic quality is the main factor responsible for further integration of the research results into the global knowledge pool. It is presumed that an abstract, being a secondary small-format text, represents an exact semantic copy of the original scientific article, hence compression is viewed as a mechanism of redistributing the functional load of the eliminated units of the original by means of increasing the informative potential of the remaining elements within the secondary small-format text. In the process of pragma-semantic and discourse analysis, a specific complex of semantic compression methods is revealed on every level of scientific abstract organization; in particular, compression means are elicited on the structural and semantic textual levels, as well as on the morphological, lexical, syntactic and graphical ones. The revealed patterns, on the one hand, expand our understanding of compression mechanisms typical of small-format texts in general; on the other hand, the practical data obtained as a result of the analysis can be used by a wide range of researchers while writing abstracts in English for publications in high-ranking international scientific journals.


Biomolecules ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1420
Author(s):  
Liudmila A. Abrosimova ◽  
Nikita A. Kuznetsov ◽  
Natalia A. Astafurova ◽  
Anastasiia R. Samsonova ◽  
Andrey S. Karpov ◽  
...  

Nicking endonucleases (NEs) are enzymes that incise only one strand of the duplex to produce a DNA molecule that is ‘nicked’ rather than cleaved in two. Since these precision tools are used in genetic engineering and genome editing, information about their mechanism of action at all stages of DNA recognition and phosphodiester bond hydrolysis is essential. For the first time, fast kinetics of the Nt.BspD6I interaction with DNA were studied by the stopped-flow technique, and changes of optical characteristics were registered for the enzyme or DNA molecules. The role of divalent metal cations was estimated at all steps of Nt.BspD6I–DNA complex formation. It was demonstrated that divalent metal ions are not required for the formation of a non-specific complex of the protein with DNA. Nt.BspD6I bound five-fold more efficiently to its recognition site in DNA than to a random DNA. DNA bending was confirmed during the specific binding of Nt.BspD6I to a substrate. The optimal size of Nt.BspD6I’s binding site in DNA as determined in this work should be taken into account in methods of detection of nucleic acid sequences and/or even various base modifications by means of NEs.


2021 ◽  
Author(s):  
Jeongjae Lee ◽  
Sunita Dey ◽  
Siân Dutton ◽  
Clare Grey

Many technologically relevant transition metal oxides for advanced energy storage and catalysis feature reduced transition metal (TM) oxides and are often nontrivial to prepare because of the need to control the reducing nature of the atmosphere in which they are synthesized. In this work, we show that an ab initio predictive synthesis strategy can be used to produce multiple gram-scale products of various MgVxOy-type phases (δ-MgV2O5, spinel MgV2O4, and MgVO3) containing V3+ or V4+ relevant for Mg-ion battery cathodes. Characterization of these phases using 25Mg solid-state NMR spectroscopy illustrates the potential of 25Mg NMR for studying reversible magnesiation and local charge distributions. Rotor-Assisted Population Transfer is used as a much needed signal-to-noise enhancement technique. The ab initio guided synthesis approach is seen as a step forward towards a predictive synthesis strategy for targeting specific complex TM oxides with variable oxidation states of technological importance.


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