Effectiveness of green tea extract (Camellia sinensis) capsule supplementation on post-exercise muscle recovery in healthy adults

Green tea (Camellia sinensis) has been widely known as a healthy drink since long time ago. One of the substances in green tea which can give health benefit is catechin, an antibacterial substance. The purpose of this research is to know the efficacy of rinsing with green tea extract to Streptococcus alpha growth on gingivitis patient’s dental plaque. The research subjects include 30 mild gingivitis patients, and these subjects are divided into two groups: treatment group (20 patients) and control group (10 patients). Ten patients of treatment group rinse their mouth with 0.25% green tea extract and 10 other patients with 0.5% green tea extract. Meanwhile, control group use Bactidol (0.1% Hexetidine). Rinsing the mouth is performed every morning and night for five days. Sampling is conducted on the first and sixth day. Before rinsing data is analyzed using ANOVA and the result shows a significant difference. ANAVA testing then is done using proportion value. ANAVA Testing result shows that there is no significant difference among the patients in the treatment group. This result indicates that the effect of rinsing with 0.25% and 0.5% green tea extract is equivalent to the control (0.1% Hexetidine) to inhibit S. alpha growth on mild gingivitis patient’s dental plaque. From these two concentrations, it has not been known which one is the most effective concentration to inhibit S. alpha growth on mild gingivitis patient.

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Effect of camellia sinensis extract on the expression level of transcription factors and cytochrome p450 genes coding phase i drug-metabolizing enzymes

Herba Polonica ◽

10.2478/hepo-2013-0023 ◽

2013 ◽

Vol 59 (4) ◽

pp. 45-59

Author(s):

Anna Bogacz ◽

Monika Karasiewicz ◽

Joanna Bartkowiak-Wieczorek ◽

Marcin Ożarowski ◽

Agnieszka Seremak-Mrozikiewicz ◽

...

Keyword(s):

Transcription Factors ◽

Green Tea ◽

Camellia Sinensis ◽

Mrna Level ◽

Green Tea Extract ◽

Expression Level ◽

Gene Transcript ◽

Mrna Levels ◽

Clinically Significant ◽

Tea Extract

Abstract Green tea (Camellia sinensis) is widely used as a popular beverage and dietary supplement that can significantly reduce the risk of many diseases. Despite the widespread use of green tea, the data regarding the safety as well as herb-drug interactions are limited. Therefore, the aim of our study was to assess the influence of standardized green tea extract (GTE) containing 61% catechins and 0.1% caffeine on the expression level of rat CYP genes and the corresponding transcription factors expression by realtime PCR. The findings showed that GTE resulted in a significant decrease of CYP2C6 expression level by 68% (p<0.001). In case of CYP3A1 and CYP3A2, the mRNA levels were also reduced by extract but in a lesser degree compared to CYP2C6. Simultaneously the significant increase in the mRNA level of CAR, RXR and GR factors was observed by 54% (p<0.05), 79% (p<0.001) and 23% (p<0.05), respectively after 10 days of green tea extract administration. In addition, there was noted a small increase of CYP1A1 expression level by 21% (p>0.05) was noted. No statistically significant differences were observed for CYP1A2 and CYP2D1/2. In the same study we observed an increase in amount of ARNT gene transcript by 27% (p<0.05) in the long-term use. However, green tea extract showed the ability to stimulate HNF-1α both after 3 and 10 days of treatment by 30% (p<0.05) and 80% (p<0.001), respectively. In contrast, no change was observed in the concentration of HNF-4α cDNA. These results suggest that GTE may change the expression of CYP enzymes, especially CYP2C6 (homologue to human CYP2C9) and may participate in clinically significant interactions with drugs metabolized by these enzymes.

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Effect of green tea extract (Camellia sinensis) on the spermatic parameters of Wistar rats submitted or not to testicular heat shock

Animal Reproduction ◽

10.1590/1984-3143-ar2019-0049 ◽

2020 ◽

Vol 17 (2) ◽

Author(s):

Joane Isis Travassos Vieira ◽

Taylane Alves da Silva ◽

Williane Maria Pereira Barbosa ◽

Gabriela Lima de Azevêdo ◽

Lúcia Cristina Pereira Arruda ◽

...

Keyword(s):

Heat Shock ◽

Green Tea ◽

Camellia Sinensis ◽

Wistar Rats ◽

Green Tea Extract ◽

Tea Extract

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PENGARUH PENGGUNAAN EKSTRAK DAUN TEH HIJAU (Camellia sinensis) PADA PROSES PEMBUATAN NAGET DAGING SAPI TERHADAP SIFAT KIMIA

Jurnal Teknologi Hasil Peternakan ◽

10.24198/jthp.v1i1.24133 ◽

2020 ◽

Vol 1 (1) ◽

pp. 34

Author(s):

Muhammad Fakhri Maulana ◽

Lilis Suryaningsih ◽

Andry Pratama

Keyword(s):

Moisture Content ◽

Green Tea ◽

Camellia Sinensis ◽

Design Method ◽

Chemical Properties ◽

Fat Content ◽

Green Tea Extract ◽

Polyphenol Content ◽

Randomized Design ◽

Tea Extract

Green tea is known as a plant who has many purpose as well as an antioxidant sources. The purpose of this research is to find out the effect of adding green tea (Camellia sinensis) extract in beef nuggets on chemical properties (moisture content, fat content, and polyphenol content). This research is an experimental research using completely randomized design method with 4 treatments and 5 repetition. The treatment that given was P1= beef nugget with no added green tea extract, P2= beef nugget + 0,5% green tea extract, P3= beef nugget + 1% green tea extract, and P4= beef nugget + 1,5% green tea extract with 5 repetition. Chemical analysis that used in this research is moisture content analysis, fat content, and polyphenols content. The obtained results then tested with anova, duncan, and polynomial test. The results showed that the treatment had a significantly real effect on polyphenols content but not on the moisture content and fat content. The addition of 1,5% green tea (Camellia sinensis) extract increase the polyphenol content of 305,96 mg/kg and influence 80,79% of the polyphenol content.

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Developing a Low-fat Drinking Yoghurt by Incorporating Green Tea (Camellia sinensis) Extract as a Functional Ingredient

Asian Journal of Dairy and Food Research ◽

10.18805/ajdfr.dr-209 ◽

2021 ◽

Author(s):

R.A.A.S. Ranasinghe ◽

M.P. Edirisinghe ◽

W.A.D. Nayananjalie

Keyword(s):

Green Tea ◽

Camellia Sinensis ◽

Titratable Acidity ◽

Green Tea Extract ◽

Organoleptic Properties ◽

Sensory Data ◽

Green Tea Leaves ◽

Microbial Analysis ◽

Tea Extract ◽

Sterilized Milk

Background: Nowadays people are health-concerned and consume more of functional foods. Thus, this study is focused on developing a drinking yoghurt incorporated with green tea (Camellia sinensis) extract as a functional ingredient.Methods: Green tea extract (GTE) was obtained by brewing 02 g of dried green tea leaves in 100 mL of water at 90°C for 30 minutes. Drinking yoghurts were prepared with standardized sterilized milk incorporated with 0%, 10%, 15%, 20% and 25% (v/v) of GTE. Physio-chemical, microbial and sensory analysis were conducted to evaluate the quality attributes of the developed product. It was stored under refrigerated conditions (4°C) for 15 days.Result: Sensory data showed that 25% green tea extract incorporated drinking yoghurt had the best organoleptic properties. It had the significantly (p less than 0.05) highest ash and lowest fat contents compared to the control. Significantly (p less than 0.05) higher pH and lower titratable acidity values were observed in 25% green tea extract incorporated yoghurt compared to the control on 15th day of storage. The microbial analysis did not show the presence of coliform. In conclusion, yoghurt incorporated with 25% (v/v) green tea extract has better organoleptic properties and nutritional value while it can be stored under refrigerated conditions for 15 days without any quality deterioration while producing at affordable price.

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To investigate the antimicrobial effects of extracted polyphenols from green tea (Camellia sinensis) and banana (Musa sp.) leaves

10.7287/peerj.preprints.1580v1 ◽

2015 ◽

Author(s):

Qin Xiang Ng

Keyword(s):

Green Tea ◽

Camellia Sinensis ◽

Bacterial Infections ◽

Bactericidal Effect ◽

Green Tea Extract ◽

Bacterial Strains ◽

E Coli ◽

Musa Sp ◽

Banana Leaves ◽

Tea Extract

In recent years, there is an emergence of antibiotic-resistant bacterial strains due to the indiscriminate use of antibiotics, commonly prescribed to treat infectious diseases. The increasing occurrence of antibiotic resistance has undoubtedly made bacterial infections a greater health risk and threat than before. In this project, the use of natural polyphenolic compounds, extracted from green tea (Camellia sinensis) and banana (Musa sp.) leaves, as a novel antimicrobial chemotherapeutic agent was investigated. This study examined their bactericidal effects on Escherichia coli and Micrococcus luteus, and also evaluated the potential synergistic ability of these polyphenol-rich extracts when used alongside the beta-lactam antibiotic ampicillin. For the same dry mass of plant material used (3g), the prepared green tea extract had a higher total polyphenol concentration than that of banana leaves extract (495.1mg/L as compared to 221.6mg/L respectively). Subsequently, bacterial broth of 105 colony forming units/ml was mixed with varying concentrations of the different test compounds before plating 10µl of the mixture and quantifying the compounds’ bactericidal effect by doing a viable count after overnight incubation. The green tea extract showed the greatest bactericidal effect on E. coli and M. luteus as compared to the banana leaves extract and ampicillin. Against E. coli, this difference was confirmed to be significant (p<0.05) using one-way ANOVA and Tukey’s post-hoc analysis. Furthermore, by applying ampicillin in close association with polyphenol-rich extracts of green tea or banana leaves, there was an enhanced bactericidal effect on the tested bacterial strains. This interaction was categorized as synergistic by the fractional bactericidal concentration index calculated (≤0.5). Ultimately, the plant polyphenols studied in this research could provide a potential adjuvant to currently-produced antibiotics and help to reduce antibiotic application concentrations; as well as prolong the effective lifespan of antibiotics through its synergistic action.

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Sterilization and protection of protein in combinations of Camellia sinensis green tea extract and gamma irradiation

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2011.01.003 ◽

2011 ◽

Vol 48 (3) ◽

pp. 452-458 ◽

Cited By ~ 2

Author(s):

Kouass Sahbani Saloua ◽

Kouass Salah ◽

Benbettaieb Nasreddine ◽

Ayari Samia ◽

Saidi Mouldi ◽

...

Keyword(s):

Gamma Irradiation ◽

Green Tea ◽

Camellia Sinensis ◽

Green Tea Extract ◽

Tea Extract

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Anticoccidial Effects of Camellia sinensis (Green Tea) Extract and Its Effect on Blood and Serum Chemistry of Broiler Chickens

Pakistan Veterinary Journal ◽

10.29261/pakvetj/2019.119 ◽

2019 ◽

Author(s):

Kexing Zhang

Keyword(s):

Green Tea ◽

Camellia Sinensis ◽

Broiler Chickens ◽

Green Tea Extract ◽

Serum Chemistry ◽

Tea Extract

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The Effect of Iron and Fat in a Diet Containing Green Tea Extract (Camellia sinensis) on the Antioxidant Capacity of Some Organs and the mRNA Expression of Specific Genes in Mice

Journal of Medicinal Food ◽

10.1089/jmf.2013.0154 ◽

2014 ◽

Vol 17 (11) ◽

pp. 1232-1238 ◽

Cited By ~ 5

Author(s):

Antonios E. Koutelidakis ◽

Dimosthenis Kizis ◽

Konstantina Argyri ◽

Alkistis Kyriakou ◽

Michael Komaitis ◽

...

Keyword(s):

Antioxidant Capacity ◽

Mrna Expression ◽

Green Tea ◽

Camellia Sinensis ◽

Green Tea Extract ◽

Tea Extract

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Circulating Hypoxia Responsive microRNAs (HRMs) and Wound Healing Potentials of Green Tea in Diabetic and Nondiabetic Rat Models

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2019/9019253 ◽

2019 ◽

Vol 2019 ◽

pp. 1-14 ◽

Cited By ~ 1

Author(s):

Hadeel A. Al-Rawaf ◽

Sami A. Gabr ◽

Ahmad H. Alghadir

Keyword(s):

Wound Healing ◽

Green Tea ◽

Camellia Sinensis ◽

Antioxidant Activities ◽

Biological Activities ◽

Green Tea Extract ◽

Pcr Analysis ◽

Diabetic Wound ◽

Diabetic Wound Healing ◽

Tea Extract

Green tea (Camellia sinensis) has many biological activities and may promote diabetic wound healing by regulation of circulating hypoxia responsive microRNAs (HRMs) which triggers the wound repairing process in diabetic and nondiabetic wounds. Thus, in this study, the potential effects of green tea extract (GTE) on the expression of miRNAs; miR-424, miR-199a, miR-210, miR-21, and fibrogenitic markers; hydroxyproline (HPX), fibronectin (FN), and nitric oxide (NO) were evaluated in wounds of diabetic and nondiabetic rats. The animals were topically treated with vaseline, 0.6% GTE, and 5%w/w povidone iodine (standard control). HPX, FN, and NO levels and microRNAs, miR-424, miR-210, miR-199a, and miR-21, were estimated in wound tissues using colorimetric, immunoassay, and molecular PCR analysis. In vitro analysis was performed to estimate active constituents and their antioxidant activities in methanolic green teat extract (GTE). Wounds treated with green tea, a dose of 0.6, healed significantly earlier than those treated with standard vehicle and vaseline treated diabetic wounds. Higher expressions of HRMs, miR-199a, and miR-21, and lower expression of HRMs, miR-424 and miR-210, were significantly reported in tissues following treatment with green tea extract compared to standard control vehicle. The tissues also contained more collagen expressed as measures of HPX, FN, and NO and more angiogenesis, compared to wounds treated with standard control vehicle. Diabetic and nondiabetic wounds treated with green tea (0.6%) for three weeks had lesser scar width and greater re-epithelialization in shorter periods when compared to standard control vehicle. Expression of HRMs, miR-199a, miR-21, and HRMs and miR-424 and miR-210 correlated positively with HPX, fibronectin, NO, better scar formation, and tensile strength and negatively with diabetes. In addition to antidiabetic and antioxidant activities of green tea components, GTE showed angiogenesis promoting activity in diabetic wound healing. In conclusion, Camellia sinensis extracts in a dose of 0.6% significantly promote more collagen and fibronectin deposition with higher expression of NO, promoting angiogenesis process via molecular controlling of circulating hypoxia responsive microRNAs: miR-424, miR-210, miR-199a, and miR-21 in diabetic and nondiabetic wounds. Our results support a functional role of circulating hypoxia responsive microRNAs: miR-424, miR-210, miR-199a, and miR-21 as potential therapeutic targets in angiogenesis and vascular remodeling in diabetic wound healing.

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