Effect of Flyash- Rice Husk Ash Blend in the Energy Efficient Geopolymer Tiles Using Industrial Wastes

Infrastructural developments are inevitable for the developing countries and hence the production of sustainable building materials is promoted worldwide. Sustainable development in the vicinity of tiles is bewildered for more than a decade. Production of conventional tiles such as cement concrete tiles, clay tiles and ceramic tiles is energy intensive approach and levies lot of strain over the adjunct ecosystem. On the other hand there are serious problems related to the disposal of flyash, Rice Husk Ash throughout the world. An approach has been taken to synthesis tiles based on these industrial byproducts as the base materials through Geopolymer technology. In this work, Geopolymer mortar after heat curing is applied as tiles. In this work, Flyash is replaced by Rice Husk Ash in various proportions such as 20, 40, 60, 80 and 100 percent. Tests such as workability, flatness, straightness, perpendicularity, water absorption, modulus of rupture and abrasion are conducted and fair results are obtained. This research also portrays the effect of Rise Husk Ash addition over the flyash based Geopolymer binder in the utility as tiles. The findings of this research work encourages the development of energy efficient tiles using industrial wastes. Keywords: Geopolymer, Rice Husk Ash, Tiles

Batik Ciprat, Identitas dan Pemberdayaan Ekonomi Penyandang Disabilitas Kampung Idiot Ponorogo

Jumlah tenaga kerja yang tinggi masih belum diimbangi dengan ketersediaan lapangan kerja yang mencukupi. Kondisi seperti ini memerlukan solusi agar angka pengangguran tidak semakin bertambah. Hasil yang ingin dicapai dari kegiatan pengabdian masyarakat ini adalah terbentuknya pola pikir dari para penyandang disabilitas yang ada di Kampung Idiot Ponorogo. Oleh karena itu perlu adanya rumusan atau Road map sebagai upaya yang dilakukan untuk mendapatkan efektivitas pembelajaran program batik ciprat bagi penyandang disabilitas di Kampung idiot Ponorogo. Metode kegiatan pengabdian ini menggunakan pendekatan kualitatif dan intensif yaitu, tenant penyandang disabilitas mendapatkan pembelajaran dan pendampingan kewirausahaan secara intensif dari pengajar, praktisi dan semua pihak yang terlibat terkait batik ciprat. Hasil menunjukkan bahwa kepemimpinan adalah kunci organisasi kewirausahaan sosial di Rumah Harapan. Terlihat dari kondisi pelatihan, pengelolaan, dan strukturisasi Rumah Harapan dapat berjalan sesuai harapan bersama. Sokongan sumberdaya merupakan bahan bakar yang menyuplai ketersediaan hal-hal yang dibutuhkan oleh Rumah Harapan, seperti adanya sumber daya manusia. Kesimpulannya yaitu pelatihan pembelajaran batik ciprat merupakan jaringan dan menjadi kunci bagi organisasi kewirausahaan sosial desa ini sehingga mampu bertahan karena hubungan kerja sama dengan stakeholder bagi Rumah Harapan bukan sekedar untuk memperluas target penjualan produk tetapi juga bentuk usaha penggalian ilmu-ilmu baru.Kata Kunci: Batik Ciprat; Identitas; Pemberdayaan Ekonomi; Kampung Idiot Ponorogo; KewirausahaanBatik Ciprat, The Identity and Economic Empowerment for Handicapped in Kampung Idiot, PonorogoABSTRACTThe availability of adequate employment has not matched the high number of workers. Conditions like this require a solution so that unemployment does not increase. The outcome of this community service activity is the formation of the mindset of persons with disabilities in Kampung Idiot Ponorogo. Therefore it is necessary to have a formula or Road map as an effort made to obtain the effectiveness of learning the ciprat batik program for people with disabilities in the idiot village of Ponorogo. This service activity method uses a qualitative and intensive approach. That is, tenants with disabilities get intensive entrepreneurial learning and mentoring from teachers, practitioners, and all parties involved with splatter batik. The results show that leadership is the key to the social entrepreneurship organization at Rumah Harapan. It can be seen from the conditions of the training, management, and structure of Rumah Harapan that it can run according to mutual expectations. Resource support is the fuel that supplies the things needed by Rumah Harapan, such as human resources. The conclusion is that the ciprat batik learning training is a network and is the key for this village social entrepreneurship organization so that it can survive because the cooperative relationship with stakeholders for Rumah Harapan is not only to expand product sales targets but also a form of business exploring new knowledge.. Keywords: Ciprat Batik; Identity; Economic Empowerment; Idiot Ponorogo Village; Entrepreneurship

Methodological Proposal for the Detection of the Composing Elements of Vulnerability Regarding Disinformation

We live in a hyper-informed society that is constantly being fed with information stimuli. That information may not be correct, and society may be vulnerable to it. We present a methodological proposal with a mixed approach that allows the learning of the characteristics and weaknesses of news consumers in the face of disinformation. Said methodology moves away from the traditional model, and with it a new, much more complete and complex way of conducting discussion groups is carried out. The qualitative approach is carried out through the creation of an online community in which subjects are encouraged to participate in different activities and tests. On the other hand, in order to obtain quantitative data, a quasi-experimental survey where respondents are exposed to various stimuli created ad hoc, which seeks to measure the interest and credibility of different news items through an orthogonal design, is carried out. The use of this methodology will allow for an expansive and intensive approach to the knowledge of societal vulnerability factors, and with the subsequent results, a solid basis of disinformation can be established, which will allow for the development of a series of strategies to combat disinformation.

Categorizing Online Climate Change Interpretation Across the National Park System

Climate change effects are evident across the National Park System, and units are encouraged to provide proactive, meaningful interpretation on the issue to cultivate informed partners and encourage collaborative stewardship. But climate change is not currently interpreted across all units of the National Park System. Anecdotal observations suggest some units highly prioritize the topic, while others do not. Thus, we conducted an assessment of current online climate change interpretation across the National Park System as one means of quantifying park engagement. Results suggest that—of the 391 units included in the analysis—37% interpreted climate change in some manner online as of February, 2019. Though our method of analysis does not fully describe park interpretive efforts, our findings provide a baseline measure of online interpretation and help to prioritize future training and support. Furthermore, our work provides a minimally intensive approach for future assessment of online climate change interpretation.

Cost-Effectiveness Analysis (CEA) of Preventive COVID-19 Vaccines by Quality-Adjusted Life Years (QALYs)

This paper merely presents the dynamic boost of the COVID-19 vaccines. The intensive approach is indicating how the effective COVID-19 vaccine promotes and distributes into various official channels. It enables the exclusive authority to devise a possible way to reduce the economic cost of COVID-19 vaccines and facilitate to a maximum level. The Cost-effectiveness analysis (CEA) method approached with Quality-Adjusted Life Years (QALYs). The key findings are revealing the length of life improves the quality of life of the middle family. The results of QALYs show that Utility Value (UV) by health and the value of statistics in countries in the term of coexistent causation of vaccines. The Pfizer (BNT162b2) and Moderna (mRNA-1273) have instantly created favorable and significant effects probably on many patients, comparatively SARS-CoV-2, AstraZeneca (AZD1222), Russia’s Sputnik (AstraZeneca), and Sinopharm Sinovac Biotech. The opportunity cost provides a valuable benefit in the future.

A DATA-INTENSIVE APPROACH TO EXPLOIT NEW GNSS SCIENCE OPPORTUNITIES

With the current GNSS infrastructure development plans, over 120 GNSS satellites (including European Galileo satellites)will provide, already this decade, continuous data, in several frequencies, without interruption and on a permanent basis.This global and permanent GNSS infrastructure constitutes a major opportunity for GNSS science applications. In themeantime, recent advances in technology have contributed "de-facto" to the deployment of a large GNSS receiver arraybased on Internet of Things (IoT), affordable smart devices easy to find in everybody’s pockets. These devices – evolvingfast at each new generation – feature an increasing number of capabilities and sensors able to collect a variety ofmeasurements, improving GNSS performance. Among these capabilities, Galileo dual band smartphones receivers andAndroid’s support for raw GNSS data recording represent major steps forward for Positioning, Navigation and Timing (PNT)data processing improvements. Information gathering from these devices, commonly referred as crowdsourcing, opensthe door to new data-intensive analysis techniques in many science domains. At this point, collaboration between variousresearch groups is essential to harness the potential hidden behind the large volumes of data generated by thiscyberinfrastructure. Cloud Computing technologies extend traditional computational boundaries, enabling execution ofprocessing components close to the data. This paradigm shift offers seamless execution of interactive algorithms andanalytics, skipping lengthy downloads and setups. The resulting scenario, defined by a GNSS Big Data repository with colocatedprocessing capabilities, sets an excellent basis for the application of Artificial Intelligence / Machine Learning (ML)technologies in the context of GNSS. This unique opportunity for science has been recognized by the European SpaceAgency (ESA) with the creation of the Navigation Scientific Office, which leverages on GNSS infrastructure to deliverinnovative solutions across multiple scientific domains.

An Adaptation of Multitiered Systems of Professional Development to Support Teacher Implementation of Tier 2 Behavioral Supports

General education teachers encounter challenges with behavior management that are compounded by limited experience and training on implementing targeted behavioral supports. One research-based method to support teacher implementation of behavioral interventions is on-site coaching. Unfortunately, coaching can be a time- and resource-intensive approach to professional development. The purpose of this article is to provide intervention team leaders with a step-by-step process for providing feasible coaching support to teacher implementers of Tier 2 behavioral supports.

Multicenter phase II study of romidepsin plus lenalidomide for patients with previously untreated peripheral T-cell lymphoma (PTCL).

7514 Background: PTCL are aggressive malignancies associated with poor prognosis when treated with cytotoxic chemotherapy. Novel agents, such as HDAC inhibitor romidepsin and immunomodulatory agent lenalidomide, have shown clinical activities as single agents and in combination in R/R PTCL. We hypothesize that upfront treatment with these agents is an effective and well-tolerated option to defer chemotherapy, particularly in patients who are not candidates for intensive approach. We report the findings of the first chemo-free combination of romidepsin plus lenalidomide as initial treatment for PTCL (ClinicalTrials.gov-NCT02232516). Methods: Patients with untreated PTCL who were over 60 or noncandidates for chemotherapy based on comorbidity CIRS score were eligible. Treatment was initiated with romidepsin 10 mg/m2 IV on d 1, 8, 15, and lenalidomide 25 mg PO on d 1-21 of 28-day cycle for up to 1 year, unless discontinued prior due to POD, toxicities, or withdrawal of consent. The primary objective was to evaluate ORR per Cheson criteria. Secondary objectives included safety, PFS, OS, DOR, and delay to chemotherapy. The sample size was 20 evaluable patients, which allows to estimate the underlying true response rate with the margin of error of an approximate 95% confidence interval equal to 0.22, assuming the true ORR = 0.5. Results: The study enrolled 29 subjects at 3 US centers, including 16 (55%) AITL, 11 (38%) PTCL-NOS, 1 ATLL and 1 EATCL. The median age was 75 (range 49-84), and M:F ratio was 1:1. Nineteen (66%) had stage III/IV disease, 23 (79%) had elevated LDH, and 9 (31%) had IPI 3-5. Treatment was well tolerated with expected side effects. Grade 3-4 hematologic toxicities included neutropenia (45%), thrombocytopenia (34%) and anemia (28%). Grade 3-4 non-hematologic toxicities included hyponatremia (45%), hypertension (38%), hypoalbuminemia (24%), fatigue (17%), hyperglycemia (14%), hypokalemia (14%), dehydration (10%), lung infection (10%) and sepsis (10%). At a median follow-up of 8 months, 20 subjects were evaluable with at least one response assessment, and received a median treatment of 6 cycles. The ORR was 75% (95%CI: 50.9%, 91.3%) with CR at 30% (11.9%, 54.3%). For AITL, the ORR was 85% (54.6%, 98.1%) with CR at 38% (13.9%, 68.4%). Median DOR was 4.2 months for all responders, and 14.3 months for CR patients. The estimated 1-yr PFS was 54.3% with 3-yr PFS at 36.2%, and the estimated 1-yr OS was 76.0% with 3-yr OS at 51.3%. Two subjects moved onto consolidative ASCT in remission, and 4 received additional cytotoxic chemotherapy after progression. Conclusions: This study provides the first demonstration that chemo-free biologic combination of romidepsin and lenalidomide is feasible and effective as initial therapy for PTCL patients who are not candidates for cytotoxic chemotherapy. These data justify further evaluation of such novel agents as a frontline strategy. Clinical trial information: NCT02232516.