To achieve the characteristics of the cash cycle module of a financial machine, such as a compact transmission mechanism, high transmission accuracy, large torque, high rotation speed, high service temperature, no lubrication, and long service life, this work presented a solution to optimize the tooth shape of a thermoplastic gear and the design of a thermoplastic gear with a limit pressure angle of 35°. Through the modeling and simulation analysis of the factors affecting the life of the gear, it was found that the gear with the improved tooth profile was superior to the control gear without the improved tooth profile in terms of sliding wear of the tooth surface, thermal deformation wear, and interference wear. The experimental results demonstrated that the wear resistance of a thermoplastic gear with a tooth profile of 35° was 1.1 times higher than that of the gear with a tooth profile of 20°, which was consistent with the simulation analysis results and can be used as a theoretical basis for thermoplastic gear design in related fields.