Simultaneous Patch-Group Sparse Coding with Dual-Weighted ℓp Minimization for Image Restoration

Sparse coding (SC) models have been proven as powerful tools applied in image restoration tasks, such as patch sparse coding (PSC) and group sparse coding (GSC). However, these two kinds of SC models have their respective drawbacks. PSC tends to generate visually annoying blocking artifacts, while GSC models usually produce over-smooth effects. Moreover, conventional ℓ1 minimization-based convex regularization was usually employed as a standard scheme for estimating sparse signals, but it cannot achieve an accurate sparse solution under many realistic situations. In this paper, we propose a novel approach for image restoration via simultaneous patch-group sparse coding (SPG-SC) with dual-weighted ℓp minimization. Specifically, in contrast to existing SC-based methods, the proposed SPG-SC conducts the local sparsity and nonlocal sparse representation simultaneously. A dual-weighted ℓp minimization-based non-convex regularization is proposed to improve the sparse representation capability of the proposed SPG-SC. To make the optimization tractable, a non-convex generalized iteration shrinkage algorithm based on the alternating direction method of multipliers (ADMM) framework is developed to solve the proposed SPG-SC model. Extensive experimental results on two image restoration tasks, including image inpainting and image deblurring, demonstrate that the proposed SPG-SC outperforms many state-of-the-art algorithms in terms of both objective and perceptual quality.

Evaluation of a novel dichoptic training method using polarising film for treatment of amblyopia

We have developed a new, low-cost, easily administered method that uses a polarising film to enable dichoptic training for amblyopia. In this study, we compared its effects with occlusion therapy using an eye patch. Fifty-eight patients (4.7 ± 0.1 years old) diagnosed with anisometric amblyopia were included and instructed to wear complete refractive correction glasses with either occlusion therapy using an eye patch (eye patch group) or dichoptic training using polarising film (polarising film group) for two hours per day. We examined the improvement in the visual acuity and adherence rate of the patients two months after treatment initiation. After training, the polarising film group showed significant improvement in visual acuity compared with the eye patch group. The adherence rate was also significantly better in the polarising film group than in the eye patch group. In both groups, there was a significant correlation between the improvement in visual acuity and adherence rate. This new dichoptic training using a polarising film was shown to be effective for anisometropic amblyopia.

Clinical Efficacy of Cortex Daphnes (Zushima) Patch in Patients With Symptomatic Knee Osteoarthritis: A Multicenter Non-Inferiority Randomized Controlled Clinical Trial

Background: Osteoarthritis (OA) is imposing substantial burdens on individuals and society with the aging population. Cortex Daphnes patch is widely used for symptomatic knee OA in China with a satisfying clinical efficacy; however, there is scant clinical evidence supporting its use. To evaluate its efficacy, we conducted a multicenter, non-inferiority, randomized, parallel-group study comparing Cortex Daphnes patch with topical nonsteroidal anti-inflammatory drugs in patients with knee OA (NCT02770950).Methods: A total of 264 symptomatic knee OA patients were treated with Cortex Daphnes or indomethacin cataplasms applied to affected sites once daily for 2 weeks. The primary outcome was improvement in knee pain on walking as assessed using a visual analog scale (VAS). The non-inferiority margin based on the full analysis population was set as –5 mm on the pain VAS. The secondary outcomes were changes of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, WOMAC scores for pain, function and stiffness, the 36-item Short Form Health Survey (SF-36), and global assessment of knees by the patients. Responder rates for pain VAS, WOMAC total score, and WOMAC pain were also included in the secondary outcomes.Results: The Cortex Daphnes patch was non-inferior to indomethacin cataplasms for the primary outcome with a group difference (Cortex Daphnes patch–indomethacin cataplasm) of 2.1 mm (95% confidence interval: 2.1–6.4); similar results were found in the per-protocol population. For all other outcomes, no significant differences were found in the full analysis set or in the per-protocol analysis set, except the responder rates for WOMAC pain was higher in the Cortex Daphnes patch group than in the indomethacin cataplasm group (78.4 vs. 64.7%, p = 0.022) in the per-protocol analysis set. Overall, 28.8% patients in the Cortex Daphnes patch group and 9.8% in the indomethacin cataplasm group reported treatment-related adverse events, the vast majority of which were mild-to-moderate skin irritation, resulting in only 3.8 and 0.8% of patients dropping out, respectively.Conclusion: The Cortex Daphnes patch, which provides satisfactory analgesic efficacy and enhances the physical function of the knee, as well as improving quality of life, may be a promising alternative to knee OA.

A randomized clinical trial on the effect of a lidocaine patch on shoulder pain relief in laparoscopic cholecystectomy

The incidence of laparoscopy-related shoulder pain reaches 90% in women. We evaluated the effect of lidocaine patch 5% on the shoulder pain after laparoscopic cholecystectomy (LC) in female patients. Total 63 female patients were randomly allocated to patch group (n = 31) and control group (n = 32). Patch group received lidocaine patch 5% and dressing retention tape on both shoulder, and control group received only dressing retention tape. Abdominal and shoulder pains were evaluated with rating on numeric rating scale (0 = no pain and 10 = the worst pain) at baseline and at 30 min, 6 h, 24 h, and 48 h after surgery. There were no significant differences in patient characteristics and operation details. The overall incidence of shoulder pain was significantly lower in patch group than in control group (42% vs. 78%, P = 0.005). The severity of shoulder pain also was significantly reduced in patch group compared to control group at 24 h and 48 h after surgery (P = 0.01 and P = 0.015, respectively). Complications related to lidocaine patch were not found except nausea. Lidocaine patch 5% reduced the incidence and severity of postoperative shoulder pain in female patients undergoing LC without complications.

Superior Capsular Reconstruction With the Long Head of the Biceps Autograft Prevents Infraspinatus Retear in Massive Posterosuperior Retracted Rotator Cuff Tears

Background: Materials and patches with increased biomechanical and biological properties and superior capsular reconstruction may change the natural history of massive rotator cuff tears (RCTs). Purpose: To compare structural and clinical outcomes among 3 surgical techniques for the treatment of massive posterosuperior RCTs: double-row (DR) technique, transosseous-equivalent (TOE) technique with absorbable patch reinforcement, and superior capsular reconstruction (SCR) with the long head of the biceps tendon (LHBT) autograft. Study Design: Cohort study; Level of evidence 3. Methods: We retrospectively analyzed the 3 techniques in patients who underwent repair of massive posterosuperior RCTs between January 2007 and March 2017. All patients completed preoperative and 24-month postoperative evaluations: range of motion, subjective shoulder value, Simple Shoulder Test, American Shoulder and Elbow Surgeons (ASES) score, visual analog scale for pain, and Constant score. Tendon integrity was assessed with ultrasound 1 year postoperatively. Results: A total of 82 patients completed the final evaluation (28 patients, DR; 30 patients, TOE + patch; 24 patients, SCR with LHBT). Groups were statistically comparable preoperatively, except for active forward elevation and tendon retraction, which were significantly worse in the SCR group ( P = .008 and P = .001, respectively). After 24 months, the mean ± SD scores for the respective groups were as follows: 76 ± 10, 72 ± 15, and 77 ± 10 for the Constant score ( P = .35); 84 ± 10, 84 ± 15, and 80 ± 15 for the ASES ( P = .61); 9 ± 2, 9 ± 3, and 8 ± 3 for the Simple Shoulder Test ( P = .23); 82 ± 15, 80 ± 18, and 75 ± 18 for the subjective shoulder value ( P = .29); and 1.4 ± 1.7, 1.8 ± 2, and 1.4 ± 1.4 for the visual analog scale ( P = .65). The strength of the operated shoulder was 4 ± 3 kg, 4.7 ± 3 kg, and 6.4 ± 1.6 kg for the DR, TOE + patch, and SCR groups, respectively ( P = .006). At 12 months postoperatively, 60.7% (17 of 28) of the DR group, 56.7% (17 of 30) of the TOE + patch group, and 91.7% (22 of 24) of the SCR group remained healed on ultrasound. The infraspinatus tendon remained healed in 75% of the DR group, 76.5% of the TOE + patch group, and 100% of the SCR with the LHBT group ( P = .006). Conclusion: In cases of massive posterosuperior RCTs, SCR with the LHBT should be considered a reliable, cost-effective treatment option that protects infraspinatus integrity.

Improved ORB Algorithm Using Three-Patch Method and Local Gray Difference

This paper presents an improved Oriented Features from Accelerated Segment Test (FAST) and Rotated BRIEF (ORB) algorithm named ORB using three-patch and local gray difference (ORB-TPLGD). ORB takes a breakthrough in real-time aspect. However, subtle changes of the image may greatly affect its final binary description. In this paper, the feature description generation is focused. On one hand, instead of pixel patch pairs comparison method used in present ORB algorithm, a three-pixel patch group comparison method is adopted to generate the binary string. In each group, the gray value of the main patch is compared with that of the other two companion patches to determine the corresponding bit of the binary description. On the other hand, the present ORB algorithm simply uses the gray size comparison between pixel patch pairs, while ignoring the information of the gray difference value. In this paper, another binary string based on the gray difference information mentioned above is generated. Finally, the feature fusion method is adopted to combine the binary strings generated in the above two steps to generate a new feature description. Experiment results indicate that our improved ORB algorithm can achieve greater performance than ORB and some other related algorithms.