Ball-Milling Synthesis of Sulfonyl Quinolines via Coupling of Haloquinolines with Sulfonic Acids

An efficient and practical approach for the synthesis of sulfonyl quinolines via ball milling promoted coupling of haloquinolines with sulfonic acid under metal-, solvent- and additive-free conditions has been developed....

Synthesis of 1-Indolyl-3,5,8-Substituted γ-Carbolines: One Pot Metal-Solvent Free Protocol and Biological Evaluation

1,5-Disubstituted indole-2-carboxaldehyde derivatives (1a–h) and glycine alkyl esters (2a–c) are shown to undergo a novel cascade imination-heterocylisation in the presence of organic base DIPEA to provide 1-indolyl 3,5,8-substituted g-carbolines (3aa–ea) in good yields. The g-carbolines are fluorescent and exhibit anticancer activities against cervical, lung, breast, skin and kidney cancers.

Synthesis, characterization, aggregation and electrochemical properties of peripheral octa-2-{[4-(2-benzylphenoxy]benzyl]thio} ethoxy group substituted cobalt(II) phthalocyanine

We were reported here, the synthesis, characterization, aggregation and electrochemical properties of 4,5-bis(2-{[4-(2- benzyl)phenoxy)benzyl]thio}ethoxy)phthalonitrile and 2,3,9,16, 17,23,24-octa[(2-{[4-(2-benzyl)phenoxy)benzyl]thio}ethoxy)] phthalociyaninatocobalt(II). CoPc were prepared by the reaction of 4,5-bis(2-{[4-(2-benzyl)phenoxy)benzyl]thio}ethoxy) phthalonitrile with the corresponding anhydrous metal salt in n-pentanol and DBU. The structures of the original compounds were identified by using elemental analysis, 1 H-NMR, 13C-NMR, IR, mass and UVvis spectroscopic data. Electrochemical redox characteristics of the compounds were determined by electroanalytical techniques such as cyclic voltammetry, square wave voltammetry. The aggregation tendencies and electrochemical redox properties of all phthalocyanines were investigated on the basis of central metal, solvent medium and substituent effects, using UV-Vis spectral.

Thermodynamic evaluation using the law of mass action under consideration of the activity coefficients in the system NdCl3-HCl (or NaOH)-H2O-DEHPA-kerosene

For the recovery of neodymium, an important rare earth metal, solvent extraction using DEHPA as extractant is a possible process for winning and recycling. A preceding study by the authors has provided extensive experimental data of the system neodymium-chloride-hydrochloric acid (or sodium hydroxide)-water-di-(2-ethylhexyl)phosphoric acid (DEHPA)-kerosene. It was found that the description of the reaction Nd3++3(DEHPA)2 ⇄ Nd(DEHP‧DEHPA)3+3H+ by an ideal mass action law is only partly satisfactory. This article investigates the contribution of several parameters to non-ideality. On this basis, expressions for activity coefficients of neodymium in the aqueous phase as well as DEHPA and neodymium in the organic phase are derived. The resulting equations are shown to represent the system with considerably better accuracy than previously possible.

Low temperature synthesis study of metal–organic framework CPO-27: investigating metal, solvent and base effects down to −78 °C

CPO-27-M (M = Co, Mg, Ni, Zn) metal–organic frameworks have been successfully synthesized at temperatures down to −78 °C in a range of solvent systems and their crystallinity and morphology analyzed by powder X-ray diffraction and scanning electron microscopy.