“L’enfer, c’est les autres”: En-gendering Sin in Middle English Religious Drama. The Case of Chester

This article investigates the relationship between sin and its retribution as depicted in three Middle English biblical plays concerned with retribution, Noah’s Flood, the Harrowing of Hell and the Last Judgement, in the Chester biblical drama collection. The plays’ general tenor is, to modern sensibilities, conservative and disciplinarian with respect to social mores. Yet, studying the portrayal of sin against the plays’ social background may uncover secular mutations of the Christian conceptualisation of sin as a function of gender as well as estate. Chester’s Last Judgement dramatises sin in accordance with fifteenth-century ecclesiastical and secular developments which criminalise people along gender-specific, not just trade-specific, lines. In showing Mulier as the only human being whom Christ leaves behind in hell after his redemptive descensus, the Harrowing dooms not just the brewers’ and alehouse-keepers’ dishonesty, as imputed to brewsters in late medieval England, but women themselves, if under the guise of their trade-related dishonesty. The underside of the Chester Noahs’ cleansing voyage is women’s ideological and social suppression. Whether or not we regard the Good Gossips’ wine-drinking – for fear of the surging waters – or Mrs Noah’s defiant resistance to her husband as a performance of the sin of humankind calling for the punitive deluge, the script gives female characters a voice not only to show their sinfulness. Rather, like the Harrowing of Hell and less so the Last Judgement, Noah’s Flood, I argue, participates in a hegemonic game which appropriates one sin of the tongue, gossip, to make it backfire against those incriminated for using it in the first place: women.

COVID-19 and geriatric population: from pathophysiology to clinical perspectives

The COVID-19 pandemic has not only led to a worldwide socio-economic depression, but has also had the highest health impact on the geriatric population. Elderly population, due to various reasons such as low immunity, pre-existing co-morbidities such as hypertension, cardiovascular diseases or diabetes, are obviously predisposed to develop severe infections and exhibit a high mortality rate. This is because of many reasons which include the atypical presentation in the geriatric population which might have led to diagnostic delay. As per the WHO guidelines to perform RT-PCR only on the symptomatic individuals, a very small portion of individuals were tested, leaving a fraction of population undiagnosed. Therefore, there remained a chance that many asymptomatic individuals such caregivers, healthcare professionals, family members were undiagnosed and might have carried this virus to the geriatric patients. Also, many countries were not prepared to handle the burden on their healthcare system which included sudden increased demand of ICU beds, mechanical ventilation etc. As a result, they had to make decision on who to be admitted. Atypical presentation in geriatric population may include afebrile or low-grade fever, absence of cough, malaise, muscle pains, dyspnoea etc. Geriatric population shows a more severe type of pneumonia, significantly higher number of neutrophils and C-reactive protein, less lymphocytes and a higher proportion of multiple lobe involvement. Extreme social suppression during COVID-19 pandemic has increased the risk of mental and physical adverse effects that has made older adults more vulnerable to depression and anxiety.

Influence of negative aff ectivity, social suppression and anxiety on motivation for health and a healthy lifestyle in coal industry workers

Introduction. A healthy lifestyle is one of the most eff ective methods of preserving health and preventing non-infectious diseases. The mechanisms and factors that infl uence the formation of motivation for health and a healthy lifestyle in employees engaged in harmful working conditions have not been suffi ciently studied. The study of these mechanisms will allow us to more eff ectively shape health-saving behavior.The aim of the study is to study negative aff ectivity, social suppression and anxiety in the formation of motivation to maintain health and a healthy lifestyle in coal industry workers.Materials and methods. A survey was conducted of 75 employees of mines and sections in the South of Kuzbass with an established diagnosis of occupational diseases, as well as 54 people who do not work in harmful working conditions (engineering and technical workers). Surveys were conducted using the method “Index of motivation to health and a healthy lifestyle”, the presence of personality type D was conducted using the DS14 questionnaire, the level of personal and situational anxiety was assessed using the Spielberger — Hanin questionnaire.Results. Th e level of motivation for health and a healthy lifestyle among patients with occupational diseases is signifi cantly lower than the level of motivation for the health of engineering and technical workers. Th e infl uence of negative reaction and social suppression on the level of motivation for health and a healthy lifestyle was not found. Th e level of situational anxiety also has no eff ect on health motivation. A higher level of personal anxiety among people with a high level of motivation for a healthy lifestyle was determined.Conclusions. Personal anxiety aff ects the level of motivation for health and a healthy lifestyle in people with occupational diseases.

Gnrh mRNA expression in the brain of cooperatively breeding female Damaraland mole-rats

The Damaraland mole-rat (Fukomys damarensis) is a eusocial, subterranean rodent, in which breeding is limited to a single reproductive pair within each colony. Non-reproductive females, while in the confines of the colony, exhibit socially induced infertility. Anovulation is thought to be caused by a disruption in the normal gonadotropin-releasing hormone (GNRH) secretion from the hypothalamus. To assess whether social suppression is associated with alteredGnrhmRNA expression in the brain, we investigated the distribution and gene expression levels by means ofin situhybridization in female breeders and non-breeders from field captured colonies of the Damaraland mole-rat. We found expression ofGnrhmRNA as a loose network in several forebrain areas of female Damaraland mole-rats with the majority of labelling in the preoptic and anterior hypothalamus. The distribution matched previous findings using immunocytochemistry in this and other social mole-rat species. Quantification of the hybridisation signal revealed no difference between breeding and non-breeding females in the average optical density of the hybridization signal and the size of the total area covered byGnrhmRNA. However, analysis along the rostro-caudal axis revealed significantly elevatedGnrhmRNA expression in the rostral preoptic region of breeders compared to non-breeders, whereas the latter had increasedGnrhmRNA expression at the caudal level of the anterior hypothalamus. This study indicates that social suppression affects the expression ofGnrhmRNA in female Damaraland mole-rats. Furthermore, differential regulation occurs within different neuron subpopulations.

The ‘secret’ source of ‘female hysteria’: the role that syphilis played in the construction of female sexuality and psychoanalysis in the late nineteenth and early twentieth centuries

In the late nineteenth and early twentieth centuries, the unspoken fear of syphilis played a significant role in the development of beliefs about female sexuality. Many women were afraid of sexual relationships with men because they feared contracting syphilis, which was, at that time, untreatable. Women also feared passing this disease on to their children. Women’s sexual aversion, or repression, became a focus for Freud and his colleagues, whose theory of psychosexual development was based on their treatment of women. This article examines the case of Dora, the memoirs of Mabel Dodge Luhan and other sources to argue that the fear of syphilis was a significant factor in upper- and middle-class women’s avoidance of heterosexual relationships. The fear of syphilis, in turn, became a significant factor in the psychoanalytic construction of female sexuality. The social suppression of the fear of syphilis has had a profound impact on theories of women’s development. The implication for psychiatry is that our models of psychological development occur within a sociocultural milieu and cannot escape suppressed aspects of our culture.

Subordinate male cichlids retain reproductive competence during social suppression

Subordinate males, which are excluded from reproduction often save energy by reducing their investment in sperm production. However, if their position in a dominance hierarchy changes suddenly they should also rapidly attain fertilization capability. Here, we asked how social suppression and ascension to dominance influences sperm quality, spermatogenesis and reproductive competence in the cichlid Astatotilapia burtoni , where reproduction is tightly coupled to social status. Dominant territorial (T) males are reproductively active while subordinate non-territorial (NT) males are suppressed, but given the opportunity, NT males will perform dominance behaviours within minutes and attain T male testes size within days. Using the thymidine analogue 5-bromo-2-deoxyuridine (BrdU) to label germ cell proliferation, we found that the spermatogenic cycle takes approximately 11–12 days, and social status had no effect on proliferation, suggesting that spermatogenesis continues during reproductive suppression. Although sperm velocity did not differ among social states, NT males had reduced sperm motility. Remarkably, males ascending in status showed sperm motility equivalent to T males within 24 h. Males also successfully reproduced within hours of social opportunity, despite four to five weeks of suppression and reduced testis size. Our data suggest that NT males maintain reproductive potential during suppression possibly as a strategy to rapidly improve reproductive fitness upon social opportunity.