C-GCN: A Flexible CSI Phase Feature Extraction Network for Error Suppression in Indoor Positioning

Channel state information (CSI) provides a fine-grained description of the signal propagation process, which has attracted extensive attention in the field of indoor positioning. However, considering the influence of environment and hardware, the phase of CSI is distorted in most cases. It is difficult to extract effective location features in multiple scenes only through the determined artificial experience model. Graph neural network has performed well in many fields in recent years, but there is still a lot of room to explore in the field of indoor positioning. In this paper, a phase feature extraction network based on multi-dimensional correlation is proposed, named Cooperation-Graph Convolution Network (C-GCN). The purpose of C-GCN is to extract new features of multiple correlation and to mine the relationship between antenna and subcarrier as much as possible. C-GCN is composed of convolution layer and graph convolution layer. In the graph convolution layer, C-GCN regards each subcarrier of each antenna as a node in the graph network, constructs the connection by the correlation between the antenna and the subcarrier, and aggregates the node vectors by graph convolution. In the convolution layer, there is a natural corresponding structure between data packets, C-GCN extracts the fluctuation with convolution in Euclidean space. C-GCN combines these two layers, and applies end-to-end supervised training to obtain effective features. Extensive experiments are conducted in typical indoor environments to verify the superior performance of C-GCN in restraining error tailing. The average positioning error of C-GCN is 1.29 m in comprehensive office and 1.71 m in garage. Combined with the amplitude feature, the average positioning error is 0.99 m in comprehensive office and 1.14 m in garage.

Universal and operational benchmarking of quantum memories

Quantum memory—the capacity to faithfully preserve quantum coherence and correlations—is essential for quantum-enhanced technology. There is thus a pressing need for operationally meaningful means to benchmark candidate memories across diverse physical platforms. Here we introduce a universal benchmark distinguished by its relevance across multiple key operational settings, exactly quantifying (1) the memory’s robustness to noise, (2) the number of noiseless qubits needed for its synthesis, (3) its potential to speed up statistical sampling tasks, and (4) performance advantage in non-local games beyond classical limits. The measure is analytically computable for low-dimensional systems and can be efficiently bounded in the experiment without tomography. We thus illustrate quantum memory as a meaningful resource, with our benchmark reflecting both its cost of creation and what it can accomplish. We demonstrate the benchmark on the five-qubit IBM Q hardware, and apply it to witness the efficacy of error-suppression techniques and quantify non-Markovian noise. We thus present an experimentally accessible, practically meaningful, and universally relevant quantifier of a memory’s capability to preserve quantum advantage.

Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis

Cell-free DNA (cfDNA) is attractive for many applications, including detecting cancer, identifying the tissue of origin, and monitoring. A fundamental task underlying these applications is SNV calling from cfDNA, which is hindered by the very low tumor content. Thus sensitive and accurate detection of low-frequency mutations (<5%) remains challenging for existing SNV callers. Here we present cfSNV, a method incorporating multi-layer error suppression and hierarchical mutation calling, to address this challenge. Furthermore, by leveraging cfDNA’s comprehensive coverage of tumor clonal landscape, cfSNV can profile mutations in subclones. In both simulated and real patient data, cfSNV outperforms existing tools in sensitivity while maintaining high precision. cfSNV enhances the clinical utilities of cfDNA by improving mutation detection performance in medium-depth sequencing data, therefore making Whole-Exome Sequencing a viable option. As an example, we demonstrate that the tumor mutation profile from cfDNA WES data can provide an effective biomarker to predict immunotherapy outcomes.

Error suppression in adiabatic quantum computing with qubit ensembles

Incorporating protection against quantum errors into adiabatic quantum computing (AQC) is an important task due to the inevitable presence of decoherence. Here, we investigate an error-protected encoding of the AQC Hamiltonian, where qubit ensembles are used in place of qubits. Our Hamiltonian only involves total spin operators of the ensembles, offering a simpler route towards error-corrected quantum computing. Our scheme is particularly suited to neutral atomic gases where it is possible to realize large ensemble sizes and produce ensemble-ensemble entanglement. We identify a critical ensemble size Nc where the nature of the first excited state becomes a single particle perturbation of the ground state, and the gap energy is predictable by mean-field theory. For ensemble sizes larger than Nc, the ground state becomes protected due to the presence of logically equivalent states and the AQC performance improves with N, as long as the decoherence rate is sufficiently low.