The exceptional advantages of channeling implantation into 4H-SiC to make abrupt deep profiles

We investigated the channeling implantation of dopant ions into 4H-SiC in detail. The advantages of channeling implantation were clarified by both experimental and Monte Carlo simulation. Extremely abrupt deep profile with box-like can be formed by channeling implantation of Al and P ions. In the case of B and N ions, retrograde-like profile can be obtained by channeling implantation. The unique dopant profile can be realized by channeling implantation. Both vertical and lateral straggling becomes small by using channeling implantation for Al ions. This technique should contribute to improve the device performance such as gate pitch scaling and low specific on-resistance.

Increase in productivity and quality based on the control of thermodynamic processes during deep profile grinding of the gas-turbine engine blade

The article provides the system of interaction of dynamic processes during deep profile grinding of complex profiles on a multiaxis machine, the influence of dynamic processes on the quality of the surface layer, the endurance limit of the gas-turbine engine blade. The method presented allows to assign corresponding grinding modes based on the forecast of the dynamics of elastic, thermal and working processes in a thermomechanical system. This technique allows to control the process of deep profile grinding to achieve the specified parameters of surface quality, the endurance limit of the blade and increase process efficiency.

Research on Performance Evaluation of PPG/Polymer Flooding System

Aiming at the PPG/polymer flooding system developed by Daqing Exploration and Development Research Institute, this paper conducts research on its viscosity increasing, viscosity stability, rheological properties, viscoelasticity and seepage ability. The experimental results show that:PPG has a thickening effect on the system, and the thickening range is between 37% and 66%;the viscosity retention rate of the PPG/polymer system is higher (88%) than the ordinary 25 million polymer solution (75%) ); Under the same shear rate conditions, the apparent viscosity of the PPG/polymer system is higher than 25 million pure polymer; the PPG/polymer system has a resilience effect, and its G’ and G” values are greater than that of a pure polymer solution;PPG/The polymer system can migrate to the deep part of the oil layer and still maintain high seepage resistance, which can realize deep profile control.

An Effective Workflow for Differentiating the Same Genus Herbs of Chrysanthemum morifolium Flower and Chrysanthemum Indicum Flower

C. morifolium flower and C. indicum flower are two closely related herbal species with similar morphological and microscopic characteristics but are discriminated in edible and medicinal purpose. However, there is no effective approach to distinguish the two herbs. A novel workflow for quickly differentiating C. morifolium flower and C. indicum flower was developed. Firstly, the difference in anti-inflammatory effects for C. morifolium flower and C. indicum flower was characterized using lipopolysaccharide-treated rats. Then HPLC fingerprint analysis for 53 batches of C. morifolium flowers and 33 batches of C. indicum flower was carried out to deep profile the chemical components. The preliminary markers were screened out by OPLS-DA, identified by HPLC-ESI-QTOF-MS, and quantified by the improved SSDMC (single reference standard to determine multiple compounds) approach. Finally, multiple statistical data mining was performed to confirm the markers and a binary logistic regression equation was built to differentiate C. morifolium flower and C. indicum flower successfully. In general, the established workflow was rapid, effective and highly feasible, which would provide a powerful tool for herb identification.

Standardized workflow for precise mid- and high-throughput proteomics of blood biofluids

Background: Accurate discovery assay workflows are critical for identifying authentic circulating protein biomarkers in diverse blood matrices. Maximizing the commonalities in the proteomic workflows between different biofluids simplifies the approach and increases the likelihood for reproducibility. We developed a workflow that allows flexibility for high and mid–throughput analysis for three blood–based proteomes: naive plasma, plasma depleted of the 14 most abundant proteins, and dried blood. Methods: Optimal conditions for sample preparation and DIA–MS analysis were established in plasma then automated and adapted for depleted plasma and whole blood. The MS workflow was modified to facilitate sensitive high–throughput or deep profile analysis with mid–throughput analysis. Analytical performance was evaluated from 5 complete workflows repeated over 3 days as well as a linearity analysis of a 5—6–point dilution curve. Result: Using our high-throughput workflow, 74%, 93%, 87% of peptides displayed an inter-day CV<30% in plasma, depleted plasma and whole blood. While the mid-throughput workflow had 67%, 90%, 78% of peptides in plasma, depleted plasma and whole blood meeting the CV<30% standard. Lower limits of detection and quantitation were determined for proteins and peptides observed in each biofluid and workflow. Combining the analysis of both high–throughput plasma fractions exceeded the number of reliably identified proteins for individual biofluids in the mid–throughput workflows. Conclusion: The workflow established here allowed for reliable detection of proteins covering a broad dynamic range. We envisage that implementation of this standard workflow on a large scale will facilitate the translation of candidate markers into clinical use.

The experimental investigation of the HPAM/phenolic resin deep profile system in fractured low-permeability reservoirs

The problem of injected water channeling along fractures exists in the process of water injection in fractured low permeability reservoir, aimed at this problem, deep profile control technology applies to plug fractures to improve the recovery of low permeability reservoir. In this paper, partially hydrolyzed polyacrylamide (HPAM) is used as water-plugging/profile-modifying agent and phenolic resin as crosslinker agent. Several profile control systems are tested to find the one which is suitable for fractured low permeability reservoirs. The performances of profile control systems are evaluated, and effects of formation water salinity, that of shearing rate and that of temperature on the performance are studied. Finally, in order to study effects of this profile control system on displacing oil, flowability experiment and core displacement experiment are applied. It shows that with the increase of salinty of prepared water and the increase of the shearing rate, the viscosity of this system decreases. With the increase of temperature, the gelling time shortens, the viscosity increases, but the stability weekens. This kind of profile control system has a good effect on plugging fractures of low permeability cores. After water flooding, this kind of profile control system is injected into cores, the recovery ratio can increase 3.5%. So the profile control system composed of HPAM/ phenolic resin can apply to deep profile control in fractured low permeability reservoir to enhance oil recovery.