E-tutoring is a hot topic in the context of virtual learning. As such learning environments become more prevalent in schools, universities or vocational training, providing adequate support for learners is becoming increasingly important – not only for individual, but also for collaborative learning. Therefore, there has been a lot of interest in using e-tutoring to foster learning processes and improve the performance of learners. Furthermore, an e-tutor can help prevent phenomena which are common in e-learning environments, such as feeling anonymous and isolated. In this chapter, we would like to first provide a theoretical introduction to e-tutoring that includes the definition, tasks and competencies of an e-tutor. Secondly, we will discuss the e-tutor in action, illustrated by a training for e-tutors and a virtual seminar which was supported by an e-tutor.