Vertical handover is one of the key technologies that will enable the connected and autonomous vehicles deployment. The emergence of vehicular networks—V2V, V2I, V2X—communications has enabled new applications, such as cooperative intelligent transport systems (C-ITS), real-time applications. However, these networks are characterized by a high level of mobility and dynamic change in the topology, which generates scattered networks. To address this problem and ensure a high level of performance, a new concept denoted heterogeneous vehicular networks (HVN) emerged, which is a key concept of the internet of vehicles (IoV). It consists in a hybridization the vehicular network (IEEE 802.11p) and cellular networks (3G/LTE/4G). In this chapter, authors introduced this new concept of IOV and its architectures and communication layers. Then they explored the different existing data relaying mechanisms in order to propose a new classification of handover approaches. After that, they presented the support of handover mechanisms in LTE and finally highlighted some handover challenges and issues.