Treatment Strategies and Outcomes for Rectal Villous Adenoma From a Single-Center Experience

AbstractOs odontoideum is an independent ossicle of variable size and shape separated from the body of C2. There are various theories on the etiology. Different hypothesis on etiology include traumatic and congenital. Because of the laxity of the ligaments associated with the anomalous odontoid, there can be associated instability at the craniovertebral junction. The authors presented their experience of treating these anomalies, their clinical presentations, evolution of the treatment strategies over years, and a brief review of literature on etiopathogenesis.

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Aggressive Treatment of Patients with Metastatic Colorectal Cancer Increases Survival: A Scandinavian Single-Center Experience

HPB Surgery ◽

10.1155/2013/727095 ◽

2013 ◽

Vol 2013 ◽

pp. 1-8 ◽

Cited By ~ 8

Author(s):

Kristoffer Watten Brudvik ◽

Simer Jit Bains ◽

Lars Thomas Seeberg ◽

Knut Jørgen Labori ◽

Anne Waage ◽

...

Keyword(s):

Colorectal Cancer ◽

Overall Survival ◽

Neoadjuvant Chemotherapy ◽

Cancer Biology ◽

Treatment Strategies ◽

Disease Free Survival ◽

Single Center ◽

Single Center Experience ◽

New Treatment ◽

Disease Free

Background. We examined overall and disease-free survivals in a cohort of patients subjected to resection of liver metastasis from colorectal cancer (CRLM) in a 10-year period when new treatment strategies were implemented. Methods. Data from 239 consecutive patients selected for liver resection of CRLM during the period from 2002 to 2011 at a single center were used to estimate overall and disease-free survival. The results were assessed against new treatment strategies and established risk factors. Results. The 5-year cumulative overall and disease-free survivals were 46 and 24%. The overall survival was the same after reresection, independently of the number of prior resections and irrespectively of the location of the recurrent disease. The time intervals between each recurrence were similar (11 ± 1 months). Patients with high tumor load given neoadjuvant chemotherapy had comparable survival to those with less extensive disease without neoadjuvant chemotherapy. Positive resection margin or resectable extrahepatic disease did not affect overall survival. Conclusion. Our data support that one still, and perhaps to an even greater extent, should seek an aggressive therapeutic strategy to achieve resectable status for recurrent hepatic and extrahepatic metastases. The data should be viewed in the context of recent advances in the understanding of cancer biology and the metastatic process.

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Toxoplasmosis, a Severe Complication in Allogeneic Hematopoietic Stem Cell Transplantation: Successful Treatment Strategies during a 5-Year Single-Center Experience

Clinical Infectious Diseases ◽

10.1086/317548 ◽

2001 ◽

Vol 32 (1) ◽

pp. e1-e8 ◽

Cited By ~ 58

Author(s):

E. Roemer ◽

I. W. Blau ◽

N. Basara ◽

M. G. Kiehl ◽

M. Bischoff ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Successful Treatment ◽

Treatment Strategies ◽

Single Center ◽

Hematopoietic Stem ◽

Single Center Experience

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Should We Perform Laboratory and Radiographic Evaluations for All Children with COVID-19?: A Single-Center Experience

Journal of Child Science ◽

10.1055/s-0041-1729630 ◽

2021 ◽

Vol 11 (01) ◽

pp. e93-e99

Author(s):

Mehmet Karaci ◽

Şirin Güven ◽

Aysun Boğa ◽

Fatih Varol ◽

Sümeyra Çalışkan ◽

...

Keyword(s):

Clinical Symptoms ◽

Treatment Strategies ◽

Information Management System ◽

Single Center ◽

Neutrophil Lymphocyte Ratio ◽

Number Of Children ◽

Single Center Experience ◽

Radiologic Findings ◽

Single Center Study ◽

Hospital Information Management System

Abstract Background The diagnostic and treatment strategies for children are limited because of the small number of children with COVID-19. A large proportion of infected children are asymptomatic or have mild symptoms. We report our experience regarding clinical characteristics, laboratory, radiologic findings, and outcomes of children with COVID-19. Materials and Methods This retrospective single-center study was conducted on children with COVID-19. The data on epidemiologic characteristics, clinical features, laboratory, and radiologic findings of patients were extracted from the hospital information management system records, and patients' forms filled upon admission. Results The median age of children was 121 months, 46.8% of the patients were females and 53.2% were males. Of the 581 children assessed, a total of 222 (38.2%) had positive test results; 69 of them (31.1%) were asymptomatic. The median absolute lymphocyte and eosinophil counts were statistically significantly lower in symptomatic children (p = 0.001; p = 0.02). Neutrophil lymphocyte ratio was statistically significantly higher in the symptomatic children (p = 0.001). Of 72 computed tomography scans, 35 (48.6%) were normal, and only 29 (40%) were consistent with classic/probable/indeterminate COVID-19 predominant pattern. Conclusion Our results showed a few laboratory abnormalities in asymptomatic polymerase chain reaction positive children; therefore, unnecessary investigation might be avoided and clinicians should consider clinical symptoms.

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