scholarly journals Risk factors for prolonged mechanical ventilation in patients with severe multiple injuries and blunt chest trauma: a single center retrospective case-control study

2018 ◽  
Vol 5 (2) ◽  
pp. 166-172 ◽  
Author(s):  
Yasuyuki Okabe
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Blunt Chest Trauma ◽  
Chest Trauma ◽  
Case Control Study ◽  
Prolonged Mechanical Ventilation ◽  
Case Control ◽  
Single Center ◽  
Retrospective Case ◽  
Control Study

scholarly journals Clinical characteristics and survival analysis in critical and non-critical patients with COVID-19 in Wuhan, China: a single-center retrospective case control study

2020 ◽  
Author(s):  
Ran Tian ◽  
Wei Wu ◽  
Chunyao Wang ◽  
Haiyu Pang ◽  
Zhiyu Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Large Scale ◽  
Case Control Study ◽  
Case Control ◽  
Hospital Death ◽  
Single Center ◽  
Retrospective Case ◽  
Critical Patients ◽  
Qsofa Score ◽  
Control Study

Abstract Since the outbreak of COVID-19 in China at the end of 2019, the world has experienced a large-scale epidemic caused by the SARS-CoV-2. Epidemiological and clinical course of COVID-19 patients have been reported, but there have been few analyses about the characteristics, predictive risk factors and outcomes of critical patients. In this single-center retrospective case-control study, 90 adult inpatients hospitalized at Tongji Hospital (Wuhan, China) were included. Demographic, clinical, laboratory test and treatment data were obtained and compared between critical and non-critical patients. We found that compared with non-critical patients, the critical patients had higher SOFA score and qSOFA scores. Critical patients had lower lymphocyte and platelet count, elevated D-dimer, decreased fibrinogen, and elevated high-sensitivity C-reactive protein (hsCRP) and interleukin-6(IL-6). More critical patients received treatment including antibiotics, anticoagulation, corticosteroid and oxygen therapy than non-critical ones. Multivariable regression showed higher qSOFA score and elevation of IL-6 were related to critical patients. Antibiotic usage and anticoagulation were associated with decreased in-hospital mortality. And critical grouping contributed greatly to in-hospital death. Critical COVID-19 patients have a more severe clinical cours. qSOFA score and elevation of IL-6 are risk factors for critical condition. Non-critical grouping, positive antibiotic application and anticoagulation may be beneficial for patient survival.

Bundle of care for blunt chest trauma patients improves analgesia but increases rates of intensive care unit admission: A retrospective case-control study

2018 ◽  
Vol 37 (3) ◽  
pp. 211-215 ◽  
Author(s):  
Cédric Carrie ◽  
Laurent Stecken ◽  
Elsa Cayrol ◽  
Vincent Cottenceau ◽  
Laurent Petit ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Intensive Care Unit Admission ◽  
Blunt Chest Trauma ◽  
Chest Trauma ◽  
Case Control Study ◽  
Case Control ◽  
Trauma Patients ◽  
Retrospective Case ◽  
Control Study

scholarly journals Clinical characteristics and survival analysis in critical and non-critical patients with COVID-19 in Wuhan, China: a single-center retrospective case control study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ran Tian ◽  
Wei Wu ◽  
Chunyao Wang ◽  
Haiyu Pang ◽  
Zhiyu Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Clinical Course ◽  
Case Control ◽  
Hospital Death ◽  
Single Center ◽  
Retrospective Case ◽  
Critical Patients ◽  
Qsofa Score ◽  
Control Study

Abstract Since the outbreak of COVID-19 in China at the end of 2019, the world has experienced a large-scale epidemic caused by the SARS-CoV-2. The epidemiological and clinical course of COVID-19 patients has been reported, but there have been few analyses about the characteristics, predictive risk factors, and outcomes of critical patients. In this single-center retrospective case–control study, 90 adult inpatients hospitalized at Tongji Hospital (Wuhan, China) were included. Demographic, clinical, laboratory tests, and treatment data were obtained and compared between critical and non-critical patients. We found that compared with non-critical patients, the critical patients had higher SOFA score and qSOFA scores. Critical patients had lower lymphocyte and platelet count, elevated D-dimer, decreased fibrinogen, and elevated high-sensitivity C-reactive protein (hsCRP), and interleukin-6(IL-6). More critical patients received treatment including antibiotics, anticoagulation, corticosteroid, and oxygen therapy than non-critical ones. Multivariable regression showed higher qSOFA score and elevation of IL-6 were related to critical patients. Antibiotic usage and anticoagulation were associated with decreased in-hospital mortality. And critical grouping contributed greatly to in-hospital death. Critical COVID-19 patients have a more severe clinical course. qSOFA score and elevation of IL-6 are risk factors for critical condition. Non-critical grouping, positive antibiotic application, and anticoagulation may be beneficial for patient survival.

scholarly journals Risk Factors for Mortality of COVID-19 Patient Based on Clinical Course: A Single Center Retrospective Case-Control Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Jing Zhang ◽  
Zhihua Wang ◽  
Xiong Wang ◽  
Zhiquan Hu ◽  
Chunguang Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
T Cells ◽  
Cd8 T Cells ◽  
Cd4 T Cells ◽  
Case Control Study ◽  
Lymphocyte Subsets ◽  
Case Control ◽  
Single Center ◽  
Retrospective Case ◽  
Control Study

Background: Epidemiological factors, clinical characteristics, and risk factors for the mortality of COVID-19 patients have been studied, but the role of complementary systems, possible inflammatory and immune response mechanisms, and detailed clinical courses are uncertain and require further study.Methods: In this single center, retrospective case-control study, we included all COVID-19 inpatients transferred or admitted to Wuhan Tongji Hospital from January 3 to March 30 2020 who had definite clinical outcomes (cured or deceased) with complete laboratory and radiological results. Clinical data were extracted from the electronic medical records, and compared between the cured and deceased patients. ROC curves were used to evaluate the prognostic value of the clinical parameters, and multivariable logistic regression analysis was performed to explore the risk factors for mortality. The correlation between the variables was evaluated by Spearman correlation analysis.Results: 208 patients were included in this study, 182 patients were cured and discharged, 26 patients died from COVID-2019. Most patients had comorbidities, with hypertension as the most common chronic disease (80; 38%). The most common symptoms at onset were fever (149; 72%), cough (137; 66%), and dyspnea (113; 54%). Elevated leucocytes, neutrophils, inflammatory biomarkers (CRP, ferritin, IL6, IL8, procalcitonin), PT, D-dimer, myocardial enzymes, BUN, decreased lymphocyte and subsets (T cells, CD4 T cells, CD8 T cells, NK cells, T cells + B cells + NK cells), and immunological factors (C3, C4) indicated poor outcome. PT, C3, and T cells were confirmed as independent prognostic factors for mortality by logistic regression models. IL6 and CPR were positively correlated with neutrophils, but negatively with lymphocytes and lymphocyte subsets except B cells. IL8 and ferritin were negatively related to T cells and CD4 T cells. Positive associations existed between C3 and T cells, CD4 T cells, and CD8 T cells, whereas there was no significant correlation between C4 and lymphocyte subsets. PT was found positively correlated with IL6, IL8, and CRP. Reverse correlations were explored between C3, C4, and PT, CK-MB, total bilirubin.Conclusions: T cells, C3, and PT were identified as independent prognostic factors for mortality. Decreased C3 and C4, dysregulation of lymphocyte subsets and cytokines may lead to death after SARS-CoV-2 infection.

Comorbidities of Bullous Pemphigoid: A Single‐Center Retrospective Case–Control Study from Turkey

2021 ◽  
Author(s):  
Sıla Kiliç Sayar ◽  
Gizem Pınar Sun ◽  
Rıfkiye Küçükoğlu
Keyword(s):  
Bullous Pemphigoid ◽  
Case Control Study ◽  
Case Control ◽  
Single Center ◽  
Retrospective Case ◽  
Control Study

scholarly journals Differences in risk factors of malignancy between men and women with type 2 diabetes: A retrospective case-control study

Oncotarget ◽  
2017 ◽  
Vol 8 (40) ◽  
pp. 66940-66950 ◽  
Author(s):  
Mariusz Dąbrowski ◽  
Elektra Szymańska-Garbacz ◽  
Zofia Miszczyszyn ◽  
Tadeusz Dereziński ◽  
Leszek Czupryniak
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Men And Women ◽  
Control Study

Risk Factors for the Development of Cytomegalovirus Resistance in Solid Organ Transplantation: A Retrospective Case-Control Study

2018 ◽  
Vol 50 (10) ◽  
pp. 3763-3768 ◽  
Author(s):  
U. Sandkovsky ◽  
F. Qiu ◽  
A.C. Kalil ◽  
A. Florescu ◽  
N. Wilson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Organ Transplantation ◽  
Case Control Study ◽  
Solid Organ Transplantation ◽  
Case Control ◽  
Solid Organ ◽  
Retrospective Case ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document