The Modified Osseodensification Visco‐Elastic (MOVE) Sinus Protocol: A Case Series to Illustrate the Combination of Osseodensification With Viscoelastic Bone Replacement Material

2021 ◽  
Author(s):  
Israel Puterman ◽  
Bradley Weinstein ◽  
Philip Walton ◽  
Matthew Fien
Keyword(s):  
Case Series ◽  
Bone Replacement Material ◽  
Bone Replacement

The Obliteration of Noncritical Size Bone Defects With Bone Dust or Bone Replacement Material (Bioactive Glass S53P4)

2019 ◽  
Vol 40 (4) ◽  
pp. e415-e423 ◽  
Author(s):  
Anne Kluge ◽  
Marcus Neudert ◽  
Christiane Kunert-Keil ◽  
Susen Lailach ◽  
Thomas Zahnert ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Bone Defects ◽  
Bone Replacement Material ◽  
Bone Replacement

Effect of CaSO4 Dissolution-Precipitation Time on Formation of Porous Carbonate Apatite as Bone Replacement Material

2020 ◽  
Vol 44 ◽  
pp. 83-90 ◽  
Author(s):  
Kusuma Eriwati Yosi ◽  
Arsista Dede ◽  
Triaminingsih Siti ◽  
Sunarso
Keyword(s):  
Functional Groups ◽  
Calcium Sulfate ◽  
Precipitation Method ◽  
Regeneration Ability ◽  
Carbonate Apatite ◽  
Type B ◽  
X Ray Diffraction ◽  
Bone Replacement Material ◽  
Bone Replacement ◽  
Thermo Fisher Scientific

Introduction: Carbonate apatite type B (C-Ap) has been used as a bone replacement material because of its osteoconductive properties. Clinically, the pores formed in bone replacement material aid in cell mobility and nutrient supply, thereby increasing the bone regeneration ability. CO32- ions found in this material are useful for maintaining a stable physiological environment in the bone in order for it to be easily absorbed by osteoclasts. Porous C-Ap type B is formed using the dissolution–precipitation method by immersing porous anhydrous CaSO4 in a mixture of carbonate and phosphate solutions. Purpose: The present study aimed to evaluate the effect of immersion ofCaSO4using the dissolution–precipitation method on the formation of porous C-Ap type B with calcium sulfate precursor hemihydrate. Method: Porous C-Ap type B was produced usinga mixture of calcium sulfate hemihydrate precursors with 50 wt% polymethylmethacrylate (PMMA) porogen and distilled water. After hardening, the calcium sulfate dihydrate containing PMMA was burned in an oven at 700°C for 4 h to remove the PMMA. The specimen was immersed in a mixture of sodium phosphate (Na3PO4) and sodium carbonate (Na2CO3) for 6, 12, and 24 h. Phase testing through X-ray diffraction (XRD) using CuKα radiation at 40 kV and 40 mA was performed. Attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR, Thermo Fisher Scientific, Waltham, Massachusetts, USA) was used for detecting the functional groups of CO32- and PO42-. Results: XRD results showed the formation of C-Ap at 6 and 12 h, but the anhydrous CaSO4 phase remained; alternatively, this phase was absent after 24 h of immersion phase andFTIR showed the presence of the functional groups of CO32- compounds. Conclusion: Porous C-Ap type B can be formed from CaSO4 precursors after 24 h of immersion using the dissolution–precipitation method.

The effects of ethylene oxide sterilization on the in vitro cytotoxicity of a bone replacement material

1990 ◽  
Vol 4 (6) ◽  
pp. 757-762 ◽  
Author(s):  
C.E. Hastings ◽  
S.A. Martin ◽  
J.R. Heath ◽  
D.E. Mark ◽  
J.L. Mansfield ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
In Vitro Cytotoxicity ◽  
Bone Replacement Material ◽  
Bone Replacement ◽  
Ethylene Oxide Sterilization

Near-net-shape fabrication of open-porous bone replacement materials of calcium phosphate and protein

2017 ◽  
Author(s):  
Berit Müller
Keyword(s):  
Calcium Phosphate ◽  
Mechanical Stability ◽  
Bone Defects ◽  
Porous Scaffolds ◽  
Synthetic Bone ◽  
Bone Replacement Material ◽  
Bone Replacement ◽  
Near Net Shape ◽  
Composition Structure ◽  
Direct Incorporation

As today’s synthetic bone implants fulfil the requirements for the repair of bone defects only in part continuous research for their improvement is ongoing. This work aims at the fabrication of bone replacement materials with bone-like properties regarding composition, structure, mechanical stability, and resorbability. As appropriate fabrication method, the slurry-based freeze gelation process was chosen. It allows the direct incorporation of active bio-relevant compounds, such as proteins, during scaffold processing. Moreover, the process enables the fabrication of complex-shaped and open-porous scaffolds. As principal components for the scaffolds calcium phosphate and protein were selected as they are biocompatible and resorbable. This work analyses the interaction between calcium phosphate and protein in suspension and investigates the suitability of the fabricated calcium phosphate/protein scaffolds as bone replacement material and drug release depot. Table of Contents SUMMARY ...

scholarly journals Clinical and Radiographic Evaluation of Nanohydroxyapatite Powder in Combination with Polylactic Acid/Polyglycolic Acid Copolymer as Bone Replacement Graft in the Surgical Treatment of Intrabony Periodontal Defects: A Retrospective Case Series Study

Materials ◽  
2020 ◽  
Vol 13 (2) ◽  
pp. 269
Author(s):  
Simone Verardi ◽  
Teresa Lombardi ◽  
Claudio Stacchi
Keyword(s):  
Surgical Treatment ◽  
Polylactic Acid ◽  
Case Series ◽  
Polyglycolic Acid ◽  
Retrospective Case ◽  
Acid Copolymer ◽  
Bone Replacement ◽  
Retrospective Case Series ◽  
Bone Replacement Graft

The aim of this retrospective case series was to evaluate the clinical efficacy of nanohydroxyapatite powder (NHA) in combination with polylactic acid/polyglycolic acid copolymer (PLGA) as a bone replacement graft in the surgical treatment of intrabony periodontal defects. Medical charts were screened following inclusion and exclusion criteria. Periodontal parameters and periapical radiographs taken before surgery and at 12-month follow-up were collected. Intra-group comparisons were performed using a two-tailed Wilcoxon signed-rank test. Twenty-five patients (13 males, 12 females, mean age 55.1 ± 10.5 years) were included in the final analysis. Mean probing depth (PD) and clinical attachment level (CAL) at baseline were 8.32 ± 1.41 mm and 9.96 ± 1.69 mm, respectively. Twelve months after surgery, mean PD was 4.04 ± 0.84 mm and CAL was 6.24 ± 1.71 mm. Both PD and CAL variations gave statistically significant results (p < 0.00001). The mean radiographic defect depth was 5.54 ± 1.55 mm and 1.48 ± 1.38 mm at baseline and at 12-month follow-up, respectively (p < 0.0001). This case series, with the limitations inherent in the study design, showed that the combination of NHA and PLGA, used as bone replacement graft in intrabony periodontal defects, may give significant improvements of periodontal parameters at 12-month follow-up.

Bioglass at 50 – A look at Larry Hench’s legacy and bioactive materials

2019 ◽  
Vol 5 (1) ◽  
pp. 178-184 ◽  
Author(s):  
David Greenspan
Keyword(s):  
Bioactive Glass ◽  
The Body ◽  
Inorganic Materials ◽  
Bioactive Glasses ◽  
Bioactive Materials ◽  
Bone Replacement Material ◽  
Bone Replacement ◽  
Young Professor

Abstract In 1969, fifty years ago, a young professor of ceramic engineering created a 4-component glass to be used as a bone replacement material. That material became known as “Bioglass” and more generally as a class of materials known as bioactive glass. Those first experiments conducted by Dr. Larry Hench completely shifted the paradigm of how the biomaterials and medical communities look at the interactions between inorganic materials and tissues in the body. This article will touch on just a few highlights of the development of bioactive glasses and relate those to the concepts of bioactivity and tissue bonding.

The Porosity and Human Gingival Cells Attachment of Synthetic Coral Scaffold for Bone Regeneration

2020 ◽  
Vol 840 ◽  
pp. 305-310
Author(s):  
Erlina Sih Mahanani ◽  
Indra Bachtiar ◽  
Ika Dewi Ana
Keyword(s):  
Tissue Engineering ◽  
Cell Attachment ◽  
Optimum Ratio ◽  
Bone Replacement Material ◽  
Bone Replacement ◽  
Bone Properties ◽  
Gingival Cells ◽  
Natural Coral ◽  
Coral Scaffold ◽  
Porosity Percentage

Porosity and interconnectivity play an important role in the success of tissue engineering because it affects cells to live and grow. Coral has been used as a bone replacement material because the structures resemble bone and have mechanical bone properties. In this study, the synthetic coral scaffold was developed to mimic the natural coral. This study aims to investigate the porosity of the scaffold and its biocompatibility while it is attached to human gingival cells. Synthetic coral scaffold in various compositions were prepared, porosity percentage measurement and human gingival cell attachment test were done. An optimum ratio of the scaffold with gelatin: CaCO3, having the highest porosity and cell attachment is obtained in 5:5. The result of this study presented that synthetic coral scaffold could provide the microenvironment to cells for life because it is supported by the highest percentage of porosity.

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