ChemInform Abstract: Heteroadamantanes and Their Derivatives. Part 18. Synthesis of 1- Phenyl-3,6-diazahomoadamantane Derivatives with Nitro and Amino Groups at the Benzene Ring and Functional Groups at C(9) of the Framework.

ChemInform ◽  
2010 ◽  
Vol 24 (44) ◽  
pp. no-no
Author(s):  
A. I. KUZNETSOV ◽  
U. BARRI ◽  
G. MAZHED ◽  
I. A. VLADIMIROVA
Keyword(s):  
Benzene Ring ◽  
Functional Groups ◽  
Amino Groups

Frameworks of Transition Metals and Linkers with Two or More Functional Groups

2000 ◽  
Vol 658 ◽  
Author(s):  
Slavi C. Sevov
Keyword(s):  
Amino Acids ◽  
Transition Metals ◽  
Functional Groups ◽  
Organic Molecules ◽  
Layered Structures ◽  
Amino Groups ◽  
Effect Of Ph ◽  
Open Framework ◽  
Acidic Conditions ◽  
New Compounds

ABSTRACTHybrid inorganic/organic materials with open-framework or layered structures are known for many transition metals linked by functionalized organic molecules such as organic diphosphonates, polycarboxylates, polynitriles, etc., species with more than one equivalent functional groups. We have studied the effect of pH on such a system of cobaltmethylenediphosphonate and report three new compounds, Na3Co[(O3PCH2PO3)(OH)],Na2Co(O3PCH2PO3)•H2O, and Co2[(O3PCH2PO3)(H2O)], that form at very basic, moderately basic, and acidic conditions, respectively. More interestingstructural chemistry should be expected from linkers with two or more different functionalities. Both the carboxylic and phosphonic groups in carboxyethylphosphonic acid are used to coordinate to cobalt or calcium atoms in the new compounds Co3(O3PCH2CH2COO)2•6H2O and Ca(O3PCH2CH2COOH)•H2O. Taking one more step further in complexity we have also studied linkers with three different functional groups, phosphonated amino acids. The structures of two new compounds, Zn(O3PCH2CH(NH3)COO) and Zn(O3PCH2CH2CH(NH3)COO), are threedimensional frameworks made of zinccoordinated by both the carboxylic and phosphonic ends of the organic molecules. The amino groups are protonated and terminal in the voids of the frameworks.

A general and practical Ni-catalyzed C–H perfluoroalkylation of (hetero)arenes

2019 ◽  
Vol 55 (47) ◽  
pp. 6723-6726 ◽  
Author(s):  
Shaoke Zhang ◽  
Nicolas Rotta-Loria ◽  
Florian Weniger ◽  
Jabor Rabeah ◽  
Helfried Neumann ◽  
...  
Keyword(s):  
Functional Groups ◽  
Free Amino ◽  
Stable Complex ◽  
Amino Groups

A direct perfluoroalkylation of (hetero)arenes using the air- and moisture-stable complex (dppf)Ni(o-tol)Cl was developed (23 examples) which allows for the synthesis of various fluorinated products and tolerates sensitive functional groups including aldehydes, free amino groups and several heterocycles.

scholarly journals Rhodium-catalyzed C–H functionalization-based approach to eight-membered lactams

2015 ◽  
Vol 6 (4) ◽  
pp. 2275-2285 ◽  
Author(s):  
Shangze Wu ◽  
Rong Zeng ◽  
Chunling Fu ◽  
Yihua Yu ◽  
Xue Zhang ◽  
...  
Keyword(s):  
Benzene Ring ◽  
Functional Groups ◽  
Room Temperature ◽  
Ambient Air

Fused tricyclic skeleton in one shot: a RhIII catalyzed formal [4 + 2 + 2] cyclization of N-pivaloyloxybenzamides 1 with 1,6-allene-enes 2 adding two cycles to the benzene ring compatible with ambient air and moisture with a tolerance of many synthetic useful functional groups at room temperature have been developed.

scholarly journals Chemical reactivity of the functional groups of insulin. Concentration-dependence studies

1984 ◽  
Vol 217 (1) ◽  
pp. 135-143 ◽  
Author(s):  
H Kaplan ◽  
M A Hefford ◽  
A M L Chan ◽  
G Oda
Keyword(s):  
Functional Groups ◽  
Chemical Reactivity ◽  
Pyrex Glass ◽  
Amino Groups ◽  
High Dilution ◽  
No Adsorption ◽  
Adsorption Effects ◽  
Labelling Procedure ◽  
High Concentrations ◽  
Reaction Vessels

A modification to the competitive labelling procedure of Duggleby and Kaplan [(1975) Biochemistry 14, 5168-5175] was used to study the reactivity of the N-termini, lysine, histidine and tyrosine groups of insulin over the concentration range 1 × 10(-3)-1 × 10(-7)M. Reactions were carried out with acetic anhydride and 1-fluoro-2,4-dinitrobenzene in 0.1 M-KCl at 37 degrees C using Pyrex glass, Tefzel and polystyrene reaction vessels. At high concentrations all groups had either normal or enhanced reactivity but at high dilution the reactivities of all functional groups became negligible. This behaviour is attributed to the adsorption of insulin to the reaction vessels. The histidine residues show a large decrease in reactivity in all reaction vessels in the concentration range 1 × 10(-3)-1 × 10(-5)M where there are no adsorption effects and where the reactivities of all other functional groups are independent of concentration. With polystyrene, where adsorption effects become significant only below 1 × 10(-6)M, the reactivity of the phenylalanine N-terminus also shows a decrease in reactivity between 1 × 10(-5) and 1 × 10(-6)M. In 1 M-KCl insulin does not absorb to Pyrex glass and under these conditions the histidine reactivity is concentration-dependent from 1 × 10(-3) to 5 × 10(-6)M and the B1 phenylalanine alpha-amino and the B29 lysine epsilon-amino reactivities from 5 × 10(-6) to 1 × 10(-7)M, whereas the reactivities of all other groups are constant. These alterations in reactivity on dilution are attributed to disruption of dimer-dimer interactions for histidine and to monomer-monomer interactions for the phenylalanine and lysine amino groups. It is concluded that the monomeric unit of insulin has essentially the same conformation in its free and associated states.

Analyses on Hydrophily and Lipophilicity of Dust in Shanghai Different Traffic Concentration Areas

2011 ◽  
Vol 356-360 ◽  
pp. 990-993
Author(s):  
Jin Xia Yan ◽  
Hai Rong Wang ◽  
Dong Fang Li
Keyword(s):  
Infrared Spectroscopy ◽  
Benzene Ring ◽  
Functional Groups ◽  
Organic Pollutants ◽  
Motor Vehicle ◽  
Vehicle Exhaust ◽  
Spectroscopy Analysis ◽  
Main Component ◽  
Living Area ◽  
Lipophilic Substances

Based on process optimizing, in this article the dust was made a extraction analysis to investigate the ratio of lipophilic substances, which was collected in shanghai different traffic concentration areas. Also, the samples was made a infrared spectroscopy analysis to investigate the organic groups contained. It illustrates that the ratio of lipophilicity in traffic-intensive areas is higher up to 90.1 percent than in living area which is 33.5 percent, those of Shanghai suburb is the littlest, only 12.3 percent. the main functional groups of dust in Shanghai traffic-intensive areas are amino, associating hydroxyl, benzene ring, alkyl and-SH, which is similar to the main component of organic pollutants in motor vehicle exhaust.

REACTION OF FORMALDEHYDE AND THIOFORMALDEHYDE WITH MERCURIPAPAIN

1965 ◽  
Vol 43 (7) ◽  
pp. 1171-1177 ◽  
Author(s):  
W. A. Darlington ◽  
L. Keay
Keyword(s):  
Enzyme Activity ◽  
Amino Acid ◽  
Functional Groups ◽  
Tertiary Structure ◽  
Colorimetric Assay ◽  
Amino Groups ◽  
Full Activity ◽  
Amino Acid Side Chains ◽  
Lysine Residues ◽  
Secondary And Tertiary Structure

In a colorimetric assay with benzoyl-DL-arginine p-nitroanilide, acetylated and benzoylated papains retain full activity. Thus the ε-amino groups of the lysine residues are not required for enzyme activity. Intramolecular crosslinking of an enzyme could in theory stabilize secondary and tertiary structure and oppose denaturation. Thioformaldehyde is much more reactive with mercuripapain than formaldehyde, incorporating much more readily into the enzyme at equivalent concentrations. Incorporation is extensive, however, on reactive functional groups on the amino acid side chains, since acetylation decreased the incorporation markedly. In no case was there evidence of heat stabilization.

Synthesis of 3,4-diaminobenzenethiol and its application in gold nanoparticle-based colorimetric determination of copper ions

RSC Advances ◽  
2016 ◽  
Vol 6 (107) ◽  
pp. 105119-105124 ◽  
Author(s):  
Chi Zhang ◽  
Li-Qiang Lu ◽  
Pan Deng ◽  
Xi-Ke Tian ◽  
Ming-Yang Liu ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Benzene Ring ◽  
Functional Groups ◽  
Copper Ions ◽  
Colorimetric Determination ◽  
Determination Of Copper

3,4-Diaminobenzenethiol can react with AuNPs via a strong covalent Au–S bond. The exposed amino functional groups on the benzene ring from neighboring AuNPs could bind to copper ions, resulting in AuNP aggregation.

FTIR Analysis of Extractable Fractions from FourIndonesian Natural Asphalts

2011 ◽  
Vol 236-238 ◽  
pp. 571-577 ◽  
Author(s):  
Ting Yao ◽  
Zhi Min Zong ◽  
Yu Gao Wang ◽  
Zhe Wen ◽  
Robert Mukasa ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Benzene Ring ◽  
Functional Groups ◽  
Acid Ester ◽  
Structural Changes ◽  
Carboxyl Groups ◽  
Ftir Analysis ◽  
Ftir Spectrometry ◽  
More Care ◽  
Transmission And Reflection

Four natural asphalts (NAs) from Buton Rock, Indonesia, which were abbreviated as BRA-A, BRA-B, BRA-C and BAR-D, were continuously extracted by solvents, subdivided into four fractions and analyzed with Fourier transform infrared (FTIR) spectrometry. The transmission and reflection FTIR techniques were used to distinguish among different samples and fractions and to examine information concerning their structure, composition and structural changes upon fractional extract. Upon FTIR analysis, the methyl, methylene, oxhydryl and carboxyl groups are the major composition of these NAs. Some strong bonds at the zones of 2922-2856 cm-1, 1707-1606 cm-1 , 1453-1373 cm-1 , 1030 cm-1 and 872-748 cm-1 are assigned to >CH2 & -CH3 & –OH in carboxlic acid, ester & benzene ring, >C=O & -C-CH3, –CH2OH, -(CH2)n- & substituted benzene, etc. Much more care should be taken to investigate both N-containing functional groups and mineral multiphase compositions probably present in BRA-B, C and D.

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