Microencapsulation of roselle ( Hibiscus sabdariffa L.) anthocyanins: Effects of drying conditions on some physicochemical properties and antioxidant activities of spray‐dried powder

A quality by design approach was used to investigate the influence of formulation composition and spray drying conditions on physicochemical properties of redispersable lipid based nanosystems loaded with Syzygium aromaticum essential oil. Four critical independent variables were studied: presence or absence of the liquid lipid oleic acid (0% - 1%), of the cationic surfactant CTAB (0% and 1%), inlet drying temperature (60 ºC -80 ºC), and ratio of the drying aids (ADJ) regarded to total formulation constituents weight (1:1 and 2:1). Resuls showed the production of spray dried redispersable lipid systems loaded with essential is feasible under very restrict conditions. Keywords: Encapsulation; lipid systems; essential oil; spray drying; redispersable.

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Use of a Taguchi Design in Hibiscus sabdariffa Extracts Encapsulated by Spray-Drying

Foods ◽

10.3390/foods9020128 ◽

2020 ◽

Vol 9 (2) ◽

pp. 128 ◽

Cited By ~ 3

Author(s):

Migdalia Sarahy Navidad-Murrieta ◽

Alejandro Pérez-Larios ◽

Jorge Alberto Sanchéz-Burgos ◽

Juan Arturo Ragazzo-Sánchez ◽

Gabriel Luna-Bárcenas ◽

...

Keyword(s):

Gum Arabic ◽

Dry Weight ◽

Good Alternative ◽

Hibiscus Sabdariffa ◽

X Ray Diffraction ◽

X Ray ◽

Multiple Variables ◽

Drying Conditions ◽

Best Parameters ◽

Spray Dried

Aqueous and ethanolic extracts of Hibiscus sabdariffa were spray-dried using maltodextrin (MD) and gum arabic (GA) as carrier agents. A Taguchi L8 experimental design with seven variables was implemented. Physicochemical properties in the encapsulates were evaluated by Ultraviolet-Visible (UV-Vis,) X-ray Diffraction (XRD), spectroscopy and gravimetric techniques. Treatments with aqueous extracts showed the highest concentration of total soluble polyphenols (TSP) 32.12–21.23 mg equivalent gallic acid (EAG)/g dry weight (DW), and antioxidant capacity (AOX) in the 2,2-azinobis-3-ethylbenzotiazoline-6-sulfonic acid (ABTS) assay. The best treatment for TSP and AOX was T4: 2.5% Hibiscus w/w, aqueous extract, decoction, extract-to-carrier ratio 1:1 (w/w), proportion to carriers (MD:GA) 80:20 (w/w), 10,000 rpm, 150 °C. The Taguchi L8 design is a tool that allows the use of multiple variables with a low number of treatments that indicate the drying conditions that give the best parameters, focusing mainly on TSP and AOX, also, it is a good alternative for the preservation and stability of the phenolic compoudns in Hibiscus.

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Spray-Dried Pectic Polysaccharide Powders: Evaluation of Physicochemical Properties for Pharmaceutical Preparations

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.93-94.417 ◽

2010 ◽

Vol 93-94 ◽

pp. 417-420 ◽

Cited By ~ 1

Author(s):

Thanyamas Nutithawat ◽

Chulalongkorn Kusonwiriyawong ◽

Garnpimol C. Ritthidej

Keyword(s):

Physicochemical Properties ◽

Feed Rate ◽

Pharmaceutical Preparations ◽

Fine Powder ◽

Inlet Temperature ◽

Pharmaceutical Dosage Forms ◽

Pectic Polysaccharide ◽

Durio Zibethinus ◽

Drying Conditions ◽

Spray Dried

Pectic polysaccharide from durian rinds (Durio Zibethinus) has been reported to mainly compose of pectin which is generally used in various pharmaceutical dosage forms. The purpose of this research was to investigate the physicochemical properties of spray-dried pectic polysaccharide powders as a function of spray drying conditions (inlet temperature, feed rate, and aspirator rate) and formulation parameters (pectic polysaccharide concentration). A mini spray dryer was used to spray dry pectic polysaccharide in formulation with maltodextrin, colloidal silica and propylene glycol. Production yields were obtained between 31.08 – 52.87%. Higher yield percentage was obtained when the inlet temperature was increased. Particle size of < 7m was from low pectic polysaccharide concentration. The pectic polysaccharide powders were bulky and the shape was almost spherical with smooth surface but collapsed at high inlet temperature and low feed rate. At 75% RH and room temperature, the powders could adsorb moisture of about 12% of the powder weight. The swelling index and mucoadhesion time that the powders attached to the porcine intestine was ranged 14 – 70 and 7 - >30 minutes, respectively. This research provides useful information for development of pectic polysaccharide as fine powder for drug delivery.

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