scholarly journals Treatment of Café‐Au‐Lait Spots Using Q‐Switched Alexandrite Laser: Analysis of Clinical Characteristics of 471 Children in Mainland China

2019 ◽  
Vol 51 (8) ◽  
pp. 694-700 ◽  
Author(s):  
Bin Zhang ◽  
Yan Chu ◽  
Zigang Xu ◽  
Yujuan Sun ◽  
Li Li ◽  
...  
2020 ◽  
Vol 65 (9) ◽  
pp. 759-769
Author(s):  
Yongxin Wen ◽  
Jiaping Wang ◽  
Qingping Zhang ◽  
Yan Chen ◽  
Xinhua Bao

2012 ◽  
Vol 175 (5-6) ◽  
pp. 489-495 ◽  
Author(s):  
Sha Lu ◽  
Changming Lu ◽  
Junmin Zhang ◽  
Yongxuan Hu ◽  
Xiqing Li ◽  
...  

2021 ◽  
Author(s):  
Xinyu Liu ◽  
Rongtao Lai ◽  
jieting tang ◽  
Yulin Hu ◽  
Yang Ding ◽  
...  

Abstract Background Herbal and Dietary Supplements (HDS) are capable of causing liver injury, however, the extent of HDS-induced liver injury compared to western medication (WM)-induced liver injury has not been well studied. Methods This was a three-year, retrospective study from 308 centers across Mainland China. 3,877 patients with liver injury due to HDS and 3,796 patients with liver injury due to WM were analyzed. Demographic and clinical characteristics, implicated agents, and severity of liver injury were analyzed using descriptive statistics. Results The HDS group was older (average age 47.65 ± 14.8 years) and had more females (57.92%). The latency to onset of liver injury was greater in the HDS group than in the WM group (41 vs. 35 days, P < 0.0001). The median levels of serum aspertate aminotransferase (AST), alanine aminotransferase (ALT), and total bilirubin (TBIL) at injury detection and at peak were significantly higher in the HDS group (P < 0 .0001). The mortality and incidence of acute liver failure (ALF) did not differ significantly between groups (0.59% vs. 0.76%, P = 0.3643; 2.31% vs. 2.13%, P = 0.6253). In patients without pre-existing liver diseases, the frequency of chronic DILI was higher in the HDS group (15.26% vs. 11.13%, P < 0 .0001). Conclusion Compared to WM-DILI, HDS-DILI is more common in older individuals and women, and has a longer latency period. HDS seems to cause more severe clinical manifestations, yet it does not increase the risk of fatal clinical outcomes. Further regulations on the use of HDS are needed.


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S588-S588
Author(s):  
fan zhangling ◽  
Xie Jing ◽  
Wang Huanling

Abstract Background The aim of present study is to conduct a systematic review to better understand the epidemiological and clinical characteristics of listeriosis cases in mainland China. Methods The six most widely used Chinese and English databases were searched. Records on cases of listeriosis in mainland China reported from 2011 to 2017 were extracted. Clinical data of patients and information on clinical isolates of Listeria were collected and analyzed. Results A total of 136 records and 562 listeriosis cases were reported. The number of cases was much higher than that reported in the past decade. The 227 included non-perinatal listeriosis cases had a mortality rate of 23.78%. Of the 231 perinatal listeriosis cases, 32.68% resulted in abortion and/or newborn death. All listeriosis cases were reported as sporadic cases. Only 3 cases were traced to a meat product, while 33.12% were healthcare-associated cases. Conclusion The number of listeriosis cases in China may have previously been underestimated. Perinatal cases in mainland China took a much higher proportion compared with what is usually described. Considering the high number of listeriosis patients in China, a comprehensive monitoring system for listeria is urgently needed in China. Disclosures All authors: No reported disclosures.


Author(s):  
Chong Tang ◽  
Keshi Zhang ◽  
Wenlong Wang ◽  
Zheng Pei ◽  
Zheng Liu ◽  
...  

AbstractCoronavirus disease 2019 (COVID-19) is a global pandemic and has been widely reported; however, a comprehensive systemic review and meta-analysis has not been conducted. We systematically investigated the clinical characteristics of COVID-19 in mainland China to guide diagnosis and treatment. We searched the PubMed, Embase, Scopus, Web of Science, Cochrane Library, bioRxiv, medRxiv, and SSRN databases for studies related to COVID-19 published or preprinted in English or Chinese from January 1 to March 15, 2020. Clinical studies on COVID-19 performed in mainland China were included. We collected primary outcomes including signs and symptoms, chest CT imaging, laboratory tests, and treatments. Study selection, data extraction, and risk of bias assessment were performed by two independent reviewers. Qualitative and quantitative synthesis was conducted, and random-effects models were applied to pooled estimates. This study is registered with PROSPERO (number CRD42020171606). Of the 3624 records identified, 147 studies (20,662 patients) were analyzed. The mean age of patients with COVID-19 was 49.40 years, 53.45% were male, and 38.52% had at least one comorbidity. Fever and cough were the most common symptoms, followed by fatigue, expectoration, and shortness of breath. Most patients with COVID-19 had abnormal chest CT findings with ground glass opacity (70.70%) or consolidation (29.91%). Laboratory findings shown lymphopenia, increased lactate dehydrogenase, increased infection-related indicators, and fibrinolytic hyperactivity. Antiviral therapy, antibiotic therapy, and corticosteroids were administered to 89.75%, 79.13%, and 35.64% of patients, respectively. Most clinical characteristics of COVID-19 are non-specific. Patients with suspected should be evaluated by virological assays and clinically treated.


2001 ◽  
Vol 120 (5) ◽  
pp. A234-A234
Author(s):  
R HILSDEN ◽  
M VERHOEF ◽  
A BEST ◽  
R ENNS

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