Abstract
Background: To investigate the attitudes and preferences toward fecal microbiota transplantation (FMT) among patients with cancer, during anti-tumor treatment in the hospital.Methods: A self-report questionnaire was administered to survey 101 patients with cancer at the Cancer Center of West China Hospital during their hospitalization and treatment. The patients were asked about their willingness to undergo FMT, and their preferences and attitudes regarding the donor, route, expenditure, and possible adverse effects. Results: Most of the patients were willing to accept FMT. Patients with younger adults (OR = 0.92, 95% CI = 0.853-0.985, P = 0.018), a higher educational level (OR, 0.24; 95% CI, 0.101-0.576; P = 0.001) and later tumor stage (OR, 0.18; 95% CI, 0.058-0.568; P = 0.003) were more likely to select FMT as a treatment option. PS score was one of the most important factors that affecting the patients’ choice of donor for FMT (χ2 = 8.69, P = 0.013), willingness to pay for FMT (χ2 = 13.02, P = 0.005), and concerns about adverse effects for FMT (χ2 = 12.18, P = 0.002). Conclusions: Clinical characteristics of patients with cancer may influence whether they choose FMT as therapy, and if willing, attitudes regarding donor, route, expenditure, and adverse effects. Nurses and other healthcare providers should assess the demographic and clinical characteristics of patients with cancer to help them make appropriate medical decisions.