RAFT-Polymerization-Induced Self-Assembly and Reorganizations: Ultrahigh-Molecular-Weight Polymer and Morphology-Tunable Micro-/Nanoparticles in One Pot

2016 ◽  
Vol 37 (21) ◽  
pp. 1735-1741 ◽  
Author(s):  
Xiao-Yun Zhang ◽  
Dong-Ming Liu ◽  
Xin-Hu Lv ◽  
Miao Sun ◽  
Xiao-Li Sun ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Self Assembly ◽  
Raft Polymerization ◽  
One Pot ◽  
Molecular Weight Polymer ◽  
Ultrahigh Molecular Weight

Oxidation-responsive micelles by a one-pot polymerization-induced self-assembly approach

2018 ◽  
Vol 9 (13) ◽  
pp. 1593-1602 ◽  
Author(s):  
Fabian H. Sobotta ◽  
Franziska Hausig ◽  
Dominic O. Harz ◽  
Stephanie Hoeppener ◽  
Ulrich S. Schubert ◽  
...  
Keyword(s):  
Self Assembly ◽  
Raft Polymerization ◽  
Assembly Process ◽  
Carrier System ◽  
One Pot ◽  
System P

Combining a sequential, one-pot RAFT polymerization with the polymerization-induced self-assembly process results in a versatile oxidation-responsive carrier system.

scholarly journals Selenol-Based Nucleophilic Reaction for the Preparation of Reactive Oxygen Species-Responsive Amphiphilic Diblock Copolymers

Polymers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 827
Author(s):  
Xiaowei An ◽  
Weihong Lu ◽  
Jian Zhu ◽  
Xiangqiang Pan ◽  
Xiulin Zhu
Keyword(s):  
Reactive Oxygen Species ◽  
Molecular Weight ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Raft Polymerization ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Amphiphilic Copolymers ◽  
Nucleophilic Reaction ◽  
Amphiphilic Diblock Copolymers

Selenide-containing amphiphilic copolymers have shown significant potential for application in drug release systems. Herein, we present a methodology for the design of a reactive oxygen species-responsive amphiphilic diblock selenide-labeled copolymer. This copolymer with controlled molecular weight and narrow molecular weight distribution was prepared by sequential organoselenium-mediated reversible addition fragmentation chain transfer (Se-RAFT) polymerization and selenol-based nucleophilic reaction. Nuclear magnetic resonance (NMR) and matrix-assisted laser desorption/ionization time-to-flight (MALDI-TOF) techniques were used to characterize its structure. Its corresponding nanomicelles successfully formed through self-assembly from the copolymer itself. Such nanomicelles could rapidly disassemble under oxidative conditions due to the fragmentation of the Se–C bond. Therefore, this type of nanomicelle based on selenide-labeled amphiphilic copolymers potentially provides a new platform for drug delivery.

Producing bimodal molecular weight distribution polymers through facile one-pot/one-step RAFT polymerization

2012 ◽  
Vol 50 (19) ◽  
pp. 4103-4109 ◽  
Author(s):  
Hongjuan Jiang ◽  
Lifen Zhang ◽  
Jian Qin ◽  
Wei Zhang ◽  
Zhenping Cheng ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Molecular Weight Distribution ◽  
Weight Distribution ◽  
Raft Polymerization ◽  
One Pot ◽  
One Step

scholarly journals Well-Defined Thermo-Responsive Copolymers Based on Oligo(Ethylene Glycol) Methacrylate and Pentafluorostyrene for the Removal of Organic Dyes from Water

Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1779
Author(s):  
Federica Zuppardi ◽  
Mario Malinconico ◽  
Franck D’Agosto ◽  
Giovanna Gomez D’Ayala ◽  
Pierfrancesco Cerruti
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Organic Contaminants ◽  
Organic Dyes ◽  
Raft Polymerization ◽  
Nile Red ◽  
Solution Temperature ◽  
Thermally Induced ◽  
Glycol Methacrylate

Thermo-responsive copolymers based on oligo(ethylene glycol) methacrylate (OEGMA, Mn = 300 g/mol) and pentafluorostyrene (PFS), coded PFG, were synthesized by RAFT polymerization, using a trithiocarbonate (CTTPC) as controlling agent. Different molar masses were targeted and dispersities lower than 1.51 were obtained. The thermally triggered self-assembly of the resulting PFG copolymers in water was investigated by dynamic light scattering (DLS). The lower critical solution temperature (LCST) slightly increased with the molecular weight in the 26–30 °C temperature range, whereas the sizes of the intermicellar aggregates formed upon self-assembly tended to decrease with increasing molecular weights (ranging from 1415 to 572 nm). The resulting thermally-induced polymer aggregates were then used to encapsulate and remove organic contaminants from water. Nile Red (NR) and Thiazole yellow G (TYG) were employed as hydrophobic and hydrophilic model contaminants, respectively. Experimental results evidenced that higher molecular weight copolymers removed up to 90% of NR from aqueous solution, corresponding to about 10 mg of dye per g of copolymer, regardless of NR concentration. The removal of TYG was lower with respect to NR, decreasing from about 40% to around 20% with TYG concentration. Finally, the copolymers were shown to be potentially recycled and reused in the treatment of contaminated water.

scholarly journals Synthesis of Nixantphos Core-Functionalized Amphiphilic Nanoreactors and Application to Rhodium-Catalyzed Aqueous Biphasic 1-Octene Hydroformylation

Polymers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1107 ◽  
Author(s):  
Ahmad Joumaa ◽  
Florence Gayet ◽  
Eduardo J. Garcia-Suarez ◽  
Jonas Himmelstrup ◽  
Anders Riisager ◽  
...  
Keyword(s):  
Self Assembly ◽  
Raft Polymerization ◽  
Star Polymer ◽  
Hydrophobic Core ◽  
Polymer Particles ◽  
One Pot ◽  
Styrene Monomer ◽  
Linear Chains ◽  
Reversible Addition ◽  
Aqueous Biphasic

A latex of amphiphilic star polymer particles, functionalized in the hydrophobic core with nixantphos and containing P(MAA-co-PEOMA) linear chains in the hydrophilic shell (nixantphos-functionalized core-crosslinked micelles, or nixantphos@CCM), has been prepared in a one-pot three-step convergent synthesis using reversible addition-fragmentation chain transfer (RAFT) polymerization in water. The synthesis involves polymerization-induced self-assembly (PISA) in the second step and chain crosslinking with di(ethylene glycol) dimethacrylate (DEGDMA) in the final step. The core consists of a functionalized polystyrene, obtained by incorporation of a new nixantphos-functionalized styrene monomer (nixantphos-styrene), which is limited to 1 mol%. The nixantphos-styrene monomer was synthesized in one step by nucleophilic substitution of the chloride of 4-chloromethylstyrene by deprotonated nixantphos in DMF at 60 °C, without interference of either phosphine attack or self-induced styrene polymerization. The polymer particles, after loading with the [Rh(acac)(CO)2] precatalyst to yield Rh-nixantphos@CCM, function as catalytic nanoreactors under aqueous biphasic conditions for the hydroformylation of 1-octene to yield n-nonanal selectively, with no significant amounts of the branched product 2-methyl-octanal.

scholarly journals Self-Assembly in ultrahigh molecular weight sphere-forming diblock copolymer thin films under strong confinement

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Wei Cao ◽  
Senlin Xia ◽  
Michael Appold ◽  
Nitin Saxena ◽  
Lorenz Bießmann ◽  
...  
Keyword(s):  
Thin Films ◽  
Molecular Weight ◽  
Film Thickness ◽  
Self Assembly ◽  
Diblock Copolymers ◽  
Grazing Incidence ◽  
Structure Evolution ◽  
Solvent Vapor ◽  
Chain Mobility ◽  
Ultrahigh Molecular Weight

AbstractUltrahigh molecular weight (UHMW) diblock copolymers (DBCs) have emerged as a promising template for fabricating large-sized nanostructures. Therefore, it is of high significance to systematically study the influence of film thickness and solvent vapor annealing (SVA) on the structure evolution of UHMW DBC thin films. In this work, spin coating of an asymmetric linear UHMW polystyrene-block-poly(methyl methacrylate) (PS-b-PMMA) DBC is used to fabricate thin films, which are spherically structured with an inter-domain distance larger than 150 nm. To enhance the polymer chain mobility and facilitate approaching equilibrium nanostructures, SVA is utilized as a post-treatment of the spin coated films. With increasing film thickness, a local hexagonal packing of PMMA half-spheres on the surface can be obtained, and the order is improved at larger thickness, as determined by grazing incidence small angle X-ray scattering (GISAXS). Additionally, the films with locally hexagonal packed half-spherical morphology show a poor order-order-poor order transition upon SVA, indicating the realization of ordered structure using suitable SVA parameters.

One-pot synthesis of well-defined amphiphilic alternating copolymer brushes based on POSS and their self-assembly in aqueous solution

RSC Advances ◽  
2015 ◽  
Vol 5 (28) ◽  
pp. 21580-21587 ◽  
Author(s):  
Zhenghe Zhang ◽  
Lizhi Hong ◽  
Jinxia Li ◽  
Feng Liu ◽  
Haibo Cai ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Polyethylene Glycol ◽  
Self Assembly ◽  
Raft Polymerization ◽  
Side Chains ◽  
One Pot ◽  
One Pot Synthesis ◽  
Alternating Copolymer ◽  
Copolymer Brushes

The amphiphilic alternating copolymer brushes P(MIPOSS-alt-VBPEG) with a sequence of alternating MIPOSS and polyethylene glycol (PEG) side chains were synthesized via RAFT polymerization, and they could form spherical aggregates.

Double thermoresponsive pentablock copolymers: synthesis by one-pot RAFT polymerization and self-assembly in aqueous solutions

2017 ◽  
Vol 8 (46) ◽  
pp. 7217-7228 ◽  
Author(s):  
Povilas Radzevicius ◽  
Medeina Steponaviciute ◽  
Tatjana Krivorotova ◽  
Ricardas Makuska
Keyword(s):  
Aqueous Solutions ◽  
Self Assembly ◽  
Raft Polymerization ◽  
Block Sequence ◽  
One Pot ◽  
Sequence Dependent ◽  
Pentablock Copolymers

Pentablock copolymers synthesized by one-pot successive RAFT polymerization are double thermoresponsive and exhibit block sequence dependent aggregation in aqueous solutions.

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