Acute Rat and Mouse Oral Toxicity Determination of Anticholinesterase Inhibitor Carbamate Pesticides: A QSTR Approach

2019 ◽  
Vol 38 (8-9) ◽  
pp. 1800151 ◽  
Author(s):  
Partha Pratim Roy ◽  
Purusottam Banjare ◽  
Sandhya Verma ◽  
Jagadish Singh
Keyword(s):  
Oral Toxicity ◽  
Carbamate Pesticides

Investigation of antiulcer activity of Pergularia extensa Linn

2020 ◽  
Vol 9 (2) ◽  
pp. 23-26
Author(s):  
Pavani C H
Keyword(s):  
Cardiac Glycosides ◽  
Methanol Extract ◽  
Methanolic Extract ◽  
Antiulcer Activity ◽  
Acute Oral Toxicity ◽  
Gastric Lesions ◽  
Oral Toxicity ◽  
Control Groups ◽  
Dose Dependent

This study was based on determination of the antiulcer activity from methanol extract was prepared by using barks of pergularia extensa linn.. Priliminary investigations showed presence of saponins, terpenes, cardiac glycosides, alkaloids and sterols. Based on OECD-423 Guidelines, the pharmacology and acute oral toxicity studies were conducted by using methanolic extract. Ulcer development was prevented by Tannins because of their vasoconstriction effects and due to protein precipitation. Similarly, the Methanolic extract of Pergularia extensa Linn shows triterpenoids and saponins. The phytoconstituents are present in the extract and these could be possible agents which are involved in order to prevent gastric lesions induced by aspirin. When compared to ulcerative control groups, this Pergularia extensa Linn., shows a dose dependent curative ratio. The extracts exhibited an inhibition percentage of 27.18, 45.47 and 61.28 at doses of 100, 200 and 400mg/kg doses respectively. 

Examination of Conditions for the Determination of Carbamate Pesticides in Soils

1992 ◽  
Vol 57 (8) ◽  
pp. 1632-1638 ◽  
Author(s):  
Věra Tatarkovičová ◽  
Zdeněk Stránský
Keyword(s):  
Activated Carbon ◽  
Solvent Extraction ◽  
Soil Type ◽  
Extraction Procedure ◽  
Purification Procedure ◽  
Factors Affecting ◽  
Carbamate Pesticides ◽  
Rp Hplc ◽  
Extracting Solvent

The procedure for the determination of carbamate pesticides in soil was optimized. The following factors affecting the final results were investigated: extracting solvent, extraction procedure, extract purification procedure, and soil type. Triple extraction with acetone and purification of the extract on a two-stage purification column containing an activated carbon-silica gel 1+1 mixture were found optimal. The extracts after treatment were analyzed by RP-HPLC with UV detection. The method developed allows carbamate pesticides in soil to be determined at concentrations in excess of 30 μg kg-1.

Ionic liquid magnetic bar microextraction and HPLC determination of carbamate pesticides in real water samples

2012 ◽  
Vol 179 (3-4) ◽  
pp. 193-199 ◽  
Author(s):  
Sha Peng ◽  
Jing Xiao ◽  
Jing Cheng ◽  
Miao Zhang ◽  
Xiaoyan Li ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Water Samples ◽  
Hplc Determination ◽  
Carbamate Pesticides ◽  
Real Water Samples

Acute Oral Toxicity Determination of Methyl Pyridyl Ketone in the Rat

1992 ◽  
Vol 11 (6) ◽  
pp. 681-681 ◽  
Author(s):  
A. C. Costello ◽  
R. C. Myers ◽  
C. E. Manderfield ◽  
T. G. Osimitz
Keyword(s):  
Acute Oral Toxicity ◽  
Oral Toxicity
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