pH‐Responsive Nanoparticles Loaded with Graphene Quantum Dots and Doxorubicin for Intracellular Imaging, Drug Delivery and Efficient Cancer Therapy

2019 ◽  
Vol 4 (20) ◽  
pp. 6004-6012 ◽  
Author(s):  
Junlong Liang ◽  
Qianwei Huang ◽  
Chenxiang Hua ◽  
Jinhua Hu ◽  
Biling Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Cancer Therapy ◽  
Graphene Quantum Dots ◽  
Ph Responsive ◽  
Intracellular Imaging

Versatile Nanoplatform Loaded with Doxorubicin and Graphene Quantum Dots/Methylene Blue for Drug Delivery and Chemophotothermal/Photodynamic Synergetic Cancer Therapy

2020 ◽  
Vol 3 (10) ◽  
pp. 7122-7132
Author(s):  
Junlong Liang ◽  
Jianjun Liu ◽  
Xiaokang Jin ◽  
Shuting Yao ◽  
Biling Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Methylene Blue ◽  
Quantum Dots ◽  
Cancer Therapy ◽  
Graphene Quantum Dots

Graphene quantum dots supported by graphene oxide as a sensitive fluorescence nanosensor for cytochrome c detection and intracellular imaging

2017 ◽  
Vol 5 (31) ◽  
pp. 6300-6306 ◽  
Author(s):  
Lin Cao ◽  
Xiangqing Li ◽  
Lixia Qin ◽  
Shi-Zhao Kang ◽  
Guodong Li
Keyword(s):  
Quantum Dots ◽  
Graphene Oxide ◽  
Cytochrome C ◽  
Graphene Quantum Dots ◽  
A549 Cells ◽  
High Sensitivity ◽  
Fluorescence Sensor ◽  
Intracellular Imaging ◽  
New Class ◽  
Sensitivity And Selectivity

A new class of Cyt c detection fluorescence sensor based on graphene quantum dots supported by graphene oxide has been facilely developed. The sensor shows a high sensitivity and selectivity for Cyt c detection, and further exhibits favorable intracellular imaging in A549 cells.

A smart drug-delivery nanosystem based on carboxylated graphene quantum dots for tumor-targeted chemotherapy

Nanomedicine ◽  
2019 ◽  
Vol 14 (15) ◽  
pp. 2011-2025 ◽  
Author(s):  
Zhen Li ◽  
Jialong Fan ◽  
Chunyi Tong ◽  
Hongyan Zhou ◽  
Wenmiao Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Folic Acid ◽  
Ethylene Glycol ◽  
Drug Delivery System ◽  
Delivery System ◽  
Graphene Quantum Dots ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Aim: Constructing a new drug-delivery system using carboxylated graphene quantum dots (cGQDs) for tumor chemotherapy in vivo. Materials & methods: A drug-delivery system was synthesized through a crosslink reaction of cGQDs, NH2-poly(ethylene glycol)-NH2 and folic acid. Results: A drug delivery system of folic acid-poly(ethylene glycol)-cGQDs was successfully constructed with ideal entrapment efficiency (97.5%) and drug-loading capacity (40.1%). Cell image indicated that the nanosystem entered into human cervical cancer cells mainly through macropinocytosis-dependent pathway. In vivo experiments showed the outstanding antitumor ability and low systemic toxicity of this nanodrug-delivery system. Conclusion: The newly developed drug-delivery system provides an important alternative for tumor therapy without causing systemic adverse effects.

scholarly journals Incorporation of Graphene Quantum Dots, Iron, and Doxorubicin in/on Ferritin Nanocages for Bimodal Imaging and Drug Delivery

2020 ◽  
Vol 3 (3) ◽  
pp. 1900183 ◽  
Author(s):  
Fatemeh Nasrollahi ◽  
Barindra Sana ◽  
David Paramelle ◽  
Samad Ahadian ◽  
Ali Khademhosseini ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Bimodal Imaging

scholarly journals Synthesis of surface capped mesoporous silica nanoparticles for pH-stimuli responsive drug delivery applications

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Drug Delivery Applications

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.

Sign in / Sign up

Export Citation Format

Share Document