Position adjustment method and distance estimation method of magnetic field supply and detection unit for magnetic hyperthermia

2017 ◽  
Vol 12 ◽  
pp. S3-S9 ◽  
Author(s):  
Loi Tonthat ◽  
Fumitaka Aki ◽  
Eiki Matsuda ◽  
Hajime Saito ◽  
Noboru Yoshimura ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Estimation Method ◽  
Distance Estimation ◽  
Magnetic Hyperthermia ◽  
Adjustment Method ◽  
Detection Unit

scholarly journals Heat induction in two-dimensional graphene–Fe3O4 nanohybrids for magnetic hyperthermia applications with artificial neural network modeling

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21702-21715
Author(s):  
M. S. Dar ◽  
Khush Bakhat Akram ◽  
Ayesha Sohail ◽  
Fatima Arif ◽  
Fatemeh Zabihi ◽  
...  
Keyword(s):  
Neural Network ◽  
Magnetic Field ◽  
Artificial Neural Network ◽  
Network Modeling ◽  
Magnetic Hyperthermia ◽  
Alternating Magnetic Field ◽  
Neural Network Modeling ◽  
Two Dimensional ◽  
Artificial Neural Network Modeling ◽  
Heat Induction

Synthesis of Fe3O4–graphene (FG) nanohybrids and magnetothermal measurements of FxG100–x (x = 0, 25, 45, 65, 75, 85, 100) nanohybrids (25 mg each) at a 633 kHz alternating magnetic field of strength 9.1 mT.

scholarly journals JOM-4S Overhauser Magnetometer and Sensitivity Estimation

Sensors ◽  
2021 ◽  
Vol 21 (22) ◽  
pp. 7698
Author(s):  
Xiaorong Gong ◽  
Shudong Chen ◽  
Shuang Zhang
Keyword(s):  
Magnetic Field ◽  
Direct Measurement ◽  
Measurement Method ◽  
Technical Specification ◽  
Estimation Method ◽  
Earth’S Magnetic Field ◽  
Sensitivity Estimation ◽  
Earth's Magnetic Field ◽  
Direct Measurement Method ◽  
Synchronous Measurement

The Overhauser magnetometer is a scalar quantum magnetometer based on the dynamic nuclear polarization (DNP) effect in the Earth’s magnetic field. Sensitivity is a key technical specification reflecting the ability of instruments to sense small variations of the Earth’s magnetic field and is closely related to the signal-to-noise ratio (SNR) of the free induction decay (FID) signal. In this study, deuterated 15N TEMPONE radical is used in our sensor to obtain high DNP enhancement. The measured SNR of the FID signal is approximately 63/1, and the transverse relaxation time T2 is 2.68 s. The direct measurement method with a single instrument and the synchronous measurement method with two instruments are discussed for sensitivity estimation in time and frequency domains under different electromagnetic interference (EMI) environments and different time periods. For the first time, the correlation coefficient of the magnetic field measured by the two instruments is used to judge the degree of the influence of the environmental noise on the sensitivity estimation. The sensitivity evaluation in the field environment is successfully realized without electrical and magnetic shields. The direct measurement method is susceptible to EMI and cannot work in general electromagnetic environments, except it is sufficiently quiet. The synchronous measurement method has an excellent ability to remove most natural and artificial EMIs and can be used under noisy environments. Direct and synchronous experimental results show that the estimated sensitivity of the JOM-4S magnetometer is approximately 0.01 nT in time domain and approximately 0.01 nT/ in frequency domain at a 3 s cycling time. This study provides a low-cost, simple, and effective sensitivity estimation method, which is especially suitable for developers and users to estimate the performance of the instrument.

Magnetic Nano-Systems in Drug Delivery and Biomedical Applications

2021 ◽  
pp. 663-695
Author(s):  
Saritha R. Shetty ◽  
Archana Upadhya
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Targeted Delivery ◽  
Biomedical Applications ◽  
Magnetic Hyperthermia ◽  
Effective Utilization ◽  
Engineering Sciences ◽  
Nanoscale Science ◽  
The Magnetic Field ◽  
Unique Ability

Nanotechnology is that sphere of technology that involves the participation of biology, chemistry, physics, and engineering sciences. Nanoscale science defines the chemistry and physics of structures lying in the range of 1-100 nm. Among the nanosystems researched, magnetic nanosystems are highlighted due their unique ability, which enables their targeting to specific locations on application of an external magnetic field. The exhibited property of these magnetic nanosystems being super-paramagnetism, there is no retention of magnetic property on removal of the magnetic field, thus enabling a reversion of the targeting process. For effective utilization of these nanosystems, they should be reduced to nanosizes, layered with biocompatible entities, stabilized, and functionalized. In the chapter, synthesis and functionalization and stabilization are elucidated. The biomedical applications such as targeted delivery, MRI, magnetic hyperthermia, tissue engineering, gene delivery, magnetic immunotherapy, magnetic detoxification, and nanomagnetic actuation are discussed.

Distance Estimation Method Based on Photon Counting LIDAR

2015 ◽  
Vol 44 (5) ◽  
pp. 501002
Author(s):  
尹文也 YIN Wen-ye ◽  
石峰 SHI Feng ◽  
何伟基 HE Wei-ji ◽  
顾国华 GU Guo-hua ◽  
陈钱 CHEN Qian
Keyword(s):  
Photon Counting ◽  
Estimation Method ◽  
Distance Estimation

scholarly journals Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment

Nanomaterials ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1713 ◽  
Author(s):  
Niklas Lucht ◽  
Ralf P. Friedrich ◽  
Sebastian Draack ◽  
Christoph Alexiou ◽  
Thilo Viereck ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Particle System ◽  
Medical Condition ◽  
Low Cost ◽  
Heat Stroke ◽  
Magnetic Hyperthermia ◽  
Modern Medicine ◽  
The Body ◽  
Jurkat Cells ◽  
Hyperthermia Treatment

Magnetic hyperthermia is a technique that describes the heating of material through an external magnetic field. Classic hyperthermia is a medical condition where the human body overheats, being usually triggered by a heat stroke, which can lead to severe damage to organs and tissue due to the denaturation of cells. In modern medicine, hyperthermia can be deliberately induced to specified parts of the body to destroy malignant cells. Magnetic hyperthermia describes the way that this overheating is induced and it has the inherent advantage of being a minimal invasive method when compared to traditional surgery methods. This work presents a particle system that offers huge potential for hyperthermia treatments, given its good loss value, i.e., the particles dissipate a lot of heat to their surroundings when treated with an ac magnetic field. The measurements were performed in a low-cost custom hyperthermia setup. Additional toxicity assessments on Jurkat cells show a very low short-term toxicity on the particles and a moderate low toxicity after two days due to the prevalent health concerns towards nanoparticles in organisms.

Inter-Vehicle Distance Estimation Method Based on Monocular Vision Using 3D Detection

2020 ◽  
Vol 69 (5) ◽  
pp. 4907-4919 ◽  
Author(s):  
Ting Zhe ◽  
Liqin Huang ◽  
Qiang Wu ◽  
Jianjia Zhang ◽  
Chenhao Pei ◽  
...  
Keyword(s):  
Estimation Method ◽  
Distance Estimation ◽  
Monocular Vision

Multi-hop distance estimation method based on regulated neighbourhood measure

2012 ◽  
Vol 6 (13) ◽  
pp. 2084-2090 ◽  
Author(s):  
G. Wu ◽  
S. Wang ◽  
Y. Dong ◽  
B. Wang
Keyword(s):  
Estimation Method ◽  
Distance Estimation

scholarly journals Nanoformulation Design Including MamC-Mediated Biomimetic Nanoparticles Allows the Simultaneous Application of Targeted Drug Delivery and Magnetic Hyperthermia

Polymers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1832 ◽  
Author(s):  
Ylenia Jabalera ◽  
Francesca Oltolina ◽  
Ana Peigneux ◽  
Alberto Sola-Leyva ◽  
Maria P. Carrasco-Jiménez ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Targeted Drug Delivery ◽  
Magnetic Hyperthermia ◽  
Simultaneous Application ◽  
Biomimetic Nanoparticles ◽  
Targeted Drug ◽  
Model Drug ◽  
Drug Nanocarriers

The design of novel nanomaterials that can be used as multifunctional platforms allowing the combination of therapies is gaining increased interest. Moreover, if this nanomaterial is intended for a targeted drug delivery, the use of several guidance methods to increase guidance efficiency is also crucial. Magnetic nanoparticles (MNPs) allow this combination of therapies and guidance strategies. In fact, MNPs can be used simultaneously as drug nanocarriers and magnetic hyperthermia agents and, moreover, they can be guided toward the target by an external magnetic field and by their functionalization with a specific probe. However, it is difficult to find a system based on MNPs that exhibits optimal conditions as a drug nanocarrier and as a magnetic hyperthermia agent. In this work, a novel nanoformulation is proposed to be used as a multifunctional platform that also allows dual complementary guidance. This nanoformulation is based on mixtures of inorganic magnetic nanoparticles (M) that have been shown to be optimal hyperthermia agents, and biomimetic magnetic nanoparticles (BM), that have been shown to be highly efficient drug nanocarriers. The presence of the magnetosome protein MamC at the surface of BM confers novel surface properties that allow for the efficient and stable functionalization of these nanoparticles without the need of further coating, with the release of the relevant molecule being pH-dependent, improved by magnetic hyperthermia. The BM are functionalized with Doxorubicin (DOXO) as a model drug and with an antibody that allows for dual guidance based on a magnetic field and on an antibody. The present study represents a proof of concept to optimize the nanoformulation composition in order to provide the best performance in terms of the magnetic hyperthermia agent and drug nanocarrier.

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