C-Reactive Protein and Diet Quality in Children

Diet Quality ◽  
2013 ◽  
pp. 75-86 ◽  
Author(s):  
Chrystalleni Lazarou ◽  
Elena Philippou
Keyword(s):  
Diet Quality ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Adiposity, depression and anxiety: interrelationship and possible mediators

2019 ◽  
Vol 53 ◽  
pp. 103 ◽  
Author(s):  
Ana Paula Gomes ◽  
Ana Luiza G. Soares ◽  
Ana M.B. Menezes ◽  
Maria Cecília Assunção ◽  
Fernando C. Wehrmeister ◽  
...  
Keyword(s):  
Physical Activity ◽  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Depressive Disorder ◽  
Generalized Anxiety Disorder ◽  
Diet Quality ◽  
Generalized Anxiety ◽  
C Reactive Protein ◽  
Major Depressive ◽  
Reactive Protein

OBJECTIVES: To explore the association between adiposity, major depressive disorder and generalized anxiety disorder, and to assess the role of inflammation, diet quality and physical activity in this association. METHODS: We used data from 2,977 individuals from the 1993 Pelotas Cohort (Brazil) who attended the 18- and 22-year follow-ups. We assessed general obesity using body mass index, fat mass index, and abdominal obesity using waist circumference. Major Depressive Disorder and generalized anxiety disorder were assessed using the mini-international neuropsychiatric interview. C-reactive protein and interleukin-6 (IL-6) levels were used as a measure of inflammation; diet quality was estimated using the revised diet quality index, and physical activity was assessed by the International physical activity questionnaire (IPAQ, min/day). The association between adiposity and major depressive disorder and generalized anxiety disorder was assessed using logistic regression, and the natural indirect effect via the mediators was estimated using G-computation. RESULTS: General obesity assessed by body mass index (OR: 2.3; 95% CI:1.13; 4.85), fat mass index (OR: 2.6; 95%CI: 1.37; 4.83), and abdominal obesity (OR: 2.5; 95%CI: 1.18; 5.39) were associated with higher odds of major depressive disorder, whereas major depressive disorder was only associated with obesity assessed by body mass index (OR=1.9; 95% CI: 1.09; 3.46). Obesity and generalized anxiety disorder were not associated. C-reactive protein, diet quality and physical activity did not mediate the effect of obesity on major depressive disorder, and C-reactive protein mediated about 25% of the effect of major depressive disorder on adiposity. CONCLUSIONS: Depression, but not generalized anxiety disorder, is associated with adiposity in both directions, with a stronger evidence for the direction obesity-depression. Inflammation explains part of the effect of major depressive disorder on obesity but not the other way around. Further research should explore other mechanisms that could be involved in the association between obesity and depression.

Antioxidant biomarkers and cardiometabolic risk markers in an Aboriginal community in remote Australia: a cross-sectional study

2020 ◽  
pp. 1-12
Author(s):  
Lenette Knudsen ◽  
Jasmine G Lyons ◽  
Kerin O’Dea ◽  
Dirk L Christensen ◽  
Julie K Brimblecombe
Keyword(s):  
Diet Quality ◽  
Cardiometabolic Risk ◽  
Aboriginal People ◽  
Cross Sectional Study ◽  
Risk Markers ◽  
Sectional Study ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Cardiometabolic Risk Markers

Abstract Objective: High-quality diets, characterised by nutrient-rich foods, are one of the foundations for health and well-being. Indicators of diet quality, antioxidants, are associated with protection against cardiometabolic diseases. The current study explores relationships between plasma antioxidants and cardiometabolic risk among Aboriginal people in Australia. Design: As part of a community-driven health promotion programme, we conducted a cross-sectional study including a health-behaviour questionnaire, plasma antioxidants and cardiometabolic risk markers (anthropometric, blood pressure measurements, fasting glucose, glycated Hb (HbA1c), lipids, C-reactive protein and albumin-creatinine-ratio) continuous and categorised into population-specific cut-offs. Antioxidants (β-carotene, β-cryptoxanthin, lycopene, lutein-zeaxanthin, retinol and α-tocopherol measured using HPLC) were applied to a principal component analysis, which aggregated these into a single component. Linear regression models were applied to investigate associations between the antioxidant component and cardiometabolic risk markers. Setting: Community in a remote area in Northern Territory, Australia. Participants: A total of 324 Aboriginal people, mean age 35·5 (range 15–75) years. Results: Antioxidant component levels were higher among individuals with higher self-reported vegetable intake (P < 0·01), higher among individuals with higher self-reported fruit intake (P = 0·05) and lower among current smokers (P = 0·06). Linear regression revealed an inverse association between the antioxidant component and C-reactive protein (β = –0·01, P < 0·01) after adjusting for confounders. Conclusion: Higher plasma antioxidant levels, indicators of diet quality, were associated with lower levels of high-sensitivity C-reactive protein in this Aboriginal population in remote Australia. This association suggests plasma antioxidants may be protective against inflammation; however, longitudinal studies are needed to examine this potentially protective relationship.

scholarly journals Diet quality is associated with circulating C-reactive protein but not irisin levels in humans

Metabolism ◽  
2014 ◽  
Vol 63 (2) ◽  
pp. 233-241 ◽  
Author(s):  
Kyung Hee Park ◽  
Lesya Zaichenko ◽  
Patricia Peter ◽  
Cynthia R. Davis ◽  
Judith A. Crowell ◽  
...  
Keyword(s):  
Diet Quality ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Diet Quality Is Inversely Associated with C-Reactive Protein Levels in Urban, Low-Income African-American and White Adults

2013 ◽  
Vol 113 (12) ◽  
pp. 1620-1631 ◽  
Author(s):  
Marie Fanelli Kuczmarski ◽  
Marc A. Mason ◽  
Deanne Allegro ◽  
Alan B. Zonderman ◽  
Michele K. Evans
Keyword(s):  
African American ◽  
Diet Quality ◽  
Low Income ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
White Adults

Diet Quality and High-Sensitivity C-Reactive Protein in Patients With Systemic Lupus Erythematosus

2018 ◽  
Vol 21 (1) ◽  
pp. 107-113 ◽  
Author(s):  
G. Pocovi-Gerardino ◽  
M. Correa-Rodríguez ◽  
J.-L. Callejas Rubio ◽  
R. Ríos Fernández ◽  
N. Ortego-Centeno ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Dietary Intake ◽  
Diet Quality ◽  
Lupus Erythematosus ◽  
Nutrient Intake ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Systemic Lupus ◽  
Reactive Protein ◽  
Serum Crp

Background and Aims: C-reactive protein (CRP) is commonly used as a biomarker for inflammation. Mild elevations of CRP have been seen in chronic autoimmune diseases like systemic lupus erythematosus (SLE), and CRP has been linked to an increased risk of cardiovascular events. Diet quality and certain dietary factors seem to influence CRP levels in healthy subjects. To date, the effect of diet on serum CRP in SLE has not been studied. Our aim was to investigate the relationship between dietary nutrients, antioxidant intake, and serum CRP in SLE. Design and Method: A cross-sectional study was conducted among 91 patients with SLE. High-sensitivity hsCRP values were determined using an immuno-turbidimetry assay in a Beckman Coulter analyzer (AU5800). Dietary intake of macro- and micronutrients was assessed through a 24-hr diet recall. Antioxidant nutrient intake was evaluated using the dietary antioxidant quality score (DAQs). Linear regression models were used to investigate the relationships between serum hsCRP levels, dietary nutrient intake, and DAQs. Results: The mean serum hsCRP level observed (3.76 ± 6.68 mg/L) was above the established normal range. However, participating SLE patients had low-quality diets, and we found no significant correlations between dietary intake of macro- or micronutrients or antioxidant nutrient intake (DAQs) and serum CRP levels. Conclusion: Our study reveals that participating SLE patients had a low-quality diet that did not influence inflammatory status measured using serum CRP levels. Further interventional studies with high-quality diets in this population are necessary to dissect the role of diet on CRP levels in SLE.

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