Dynamic Components

Pro Vue.js 2 ◽  
2018 ◽  
pp. 541-564
Author(s):  
Adam Freeman
Keyword(s):  
Author(s):  
Chloe Alexandre ◽  
Alban Latremoliere ◽  
Patrick H. Finan

With the advent of modern lifestyles, there has been a significant extension of daily activities, mostly at the cost of sleep. Lack of sleep affects many biological systems, including various cognitive functions, the immune system, metabolism, and pain. Both sleep and pain are complex neurological processes that encompass many dynamic components. As a result, defining the precise interactions between these two systems represents a challenge, especially for chronic paradigms. This chapter describes how sleep is measured and how it can be experimentally altered in humans and animal models, and, in turn, how sleep disturbances, either acute or chronic, can affect different aspects of pain. Possible mechanisms involved are discussed, including an increase in inflammatory processes, a loss of nociceptive inhibitory pathways, and a defect in the cognitive processing of noxious inputs.


2021 ◽  
Vol 7 (7) ◽  
pp. 567
Author(s):  
Eyal Ben-Dor Cohen ◽  
Micha Ilan ◽  
Oded Yarden

Marine sponges harbor a diverse array of microorganisms and the composition of the microbial community has been suggested to be linked to holo-biont health. Most of the attention concerning sponge mycobiomes has been given to sponges present in shallow depths. Here, we describe the presence of 146 culturable mycobiome taxa isolated from mesophotic niche (100 m depth)-inhabiting samples of Agelas oroides, in the Mediterranean Sea. We identify some potential in vitro interactions between several A. oroides-associated fungi and show that sponge meso-hyl extract, but not its predominantly collagen-rich part, is sufficient to support hyphal growth. We demonstrate that changes in the diversity of culturable mycobiome constituents occur following sponge transplantation from its original mesophotic habitat to shallow (10 m) waters, where historically (60 years ago) this species was found. We conclude that among the 30 fungal genera identified as associated with A. oroides, Aspergillus, Penicillium and Trichoderma constitute the core mycobiome of A. oroides, and that they persist even when the sponge is transplanted to a suboptimal environment, indicative of the presence of constant, as well as dynamic, components of the sponge mycobiome. Other genera seemed more depth-related and appeared or disappeared upon host’s transfer from 100 to 10 m.


2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Ishrat Rashid ◽  
Ubaid Yaqoob

Abstract Background Genus Fritillaria is one among the biggest genera of family Liliaceae comprising of around 130–165 species. Fritillaria is viewed as a significant genus and a source of significant pharmaceutically active compounds utilized in conventional drugs by folklore. Fritillaria is utilized worldwide as medication and food. Different chemically dynamic components separated from genus Fritillaria, their phytochemistry with structure and pharmacology of these compounds have been extensively reviewed. Main body Fritillaria is utilized for treatment of dyspepsia, chest injury, tuberculosis, cough, asthma, gout, bronchitis, dysuria, sinus, boils, stomatitis, malaria, insanity, anaemia, immunity promoter, remedy for child emaciation, fever, burning sensation, phthisis and broncho-asthma, heart diseases, dysfunction of breathing and nervous system, etc. Different chemical components isolated from genus Fritillaria include around 120 alkaloids, 15 terpenoids as well as saponins, glycosides, volatile components, nucleosides, amino acids, nucleobases, flavonoids, fatty acids and so forth. Conclusions Many Fritillaria species have been utilized in traditional Chinese medication on account of their effects of clearing heat, moistening the lung, alleviating cough, asthma, tumours, scrofula and so on. Fritillaria is utilized for treatment of dyspepsia, chest injury, tuberculosis, cough, asthma, gout, bronchitis, dysuria, sinus, boils, stomatitis, malaria, insanity, anaemia, immunity promoter, remedy for child emaciation, also for fever, burning sensation, phthisis and broncho-asthma, heart diseases, dysfunction of breathing and nervous system, etc.


Author(s):  
D J Cole ◽  
D Cebon

The objective of the work described in this paper is to establish guidelines for the design of passive suspensions that cause minimum road damage. An efficient procedure for calculating a realistic measure of road damage (the 95th percentile aggregate fourth power force) in the frequency domain is derived. Simple models of truck vibration are then used to examine the influence of suspension parameters on this road damage criterion and to select optimal values. It is found that to minimize road damage a suspension should have stiffness about one fifth of current air suspensions and damping up to twice that typically provided. The use of an anti-roll bar allows a high roll-over threshold without increasing road damage. It is thought that optimization in the pitch-plane should exclude correlation between the axles, to ensure that the optimized suspension parameters are robust to payload and speed changes. A three-dimensional ‘whole-vehicle’ model of an air suspended articulated vehicle is validated against measured tyre force histories. Optimizing the suspension stiffness and damping results in a 5.8 per cent reduction in road damage by the whole vehicle (averaged over three speeds). This compares with a 40 per cent reduction if the dynamic components of the tyre forces are eliminated completely.


2004 ◽  
Vol 99-100 ◽  
pp. 223-226
Author(s):  
H. Puszkarski ◽  
J.-C.S. Lévy ◽  
M. Krawczyk

The equations of motion are derived for a magnetic planar system with dipolar interactions taken into account. Magnetostatic waves propagating perpendicularly to the sample surface and dipolar field static and dynamic components are calculated for the case when saturating field is applied perpendicularly to the sample surface. The corresponding frequency spectra and mode profiles are computed numerically with emphasis laid on size effects. It is established that two lowest-frequency modes are surface-localized modes. These modes preserve their surface-localized character with growing sample dimensions.


Solid Earth ◽  
2019 ◽  
Vol 10 (6) ◽  
pp. 2167-2178 ◽  
Author(s):  
Ömer F. Bodur ◽  
Patrice F. Rey

Abstract. Much effort is being made to extract the dynamic components of the Earth's topography driven by density heterogeneities in the mantle. Seismically mapped density anomalies have been used as an input into mantle convection models to predict the present-day mantle flow and stresses applied on the Earth's surface, resulting in dynamic topography. However, mantle convection models give dynamic topography amplitudes generally larger by a factor of ∼2, depending on the flow wavelength, compared to dynamic topography amplitudes obtained by removing the isostatically compensated topography from the Earth's topography. In this paper, we use 3-D numerical experiments to evaluate the extent to which the dynamic topography depends on mantle rheology. We calculate the amplitude of instantaneous dynamic topography induced by the motion of a small spherical density anomaly (∼100 km radius) embedded into the mantle. Our experiments show that, at relatively short wavelengths (<1000 km), the amplitude of dynamic topography, in the case of non-Newtonian mantle rheology, is reduced by a factor of ∼2 compared to isoviscous rheology. This is explained by the formation of a low-viscosity channel beneath the lithosphere and a decrease in thickness of the mechanical lithosphere due to induced local reduction in viscosity. The latter is often neglected in global mantle convection models. Although our results are strictly valid for flow wavelengths less than 1000 km, we note that in non-Newtonian rheology all wavelengths are coupled, and the dynamic topography at long wavelengths will be influenced.


2020 ◽  
Vol 20 (1) ◽  
pp. 12-23
Author(s):  
N. А. Gaidamakin ◽  
◽  
N. I. Sinadsky ◽  
P. V. Sushkov ◽  
◽  
...  

The article presents a solution to the problem of synthesizing training tasks and data arrays when organizing a computer training platform for conducting practical exercises to investigate information security incidents. Two main stages of the synthesis of the background and situa-tional components of the conditionally real data arrays based on the structural-parametric model of interaction between users of information and telecommunication services are pro-posed: the formation of static and dynamic components. 14КОМПЛЕС НЫЙИ. ТОАИЦ-МЛИМПЧ К ЕЛЙИДЗ-ВЕИЛЛИУ МЙОДО Р 1Ь35Х / 2020Вступление в силу Федерального закона «О безопасности критической информацион-ной инфраструктуры Российской Федера-ции» свидетельствует об актуальности и зна-чимости решения задачи по обнаружению, предупреждению и ликвидации последствий компьютерных атак и реагирования на ком-пьютерные инциденты. Условием качествен-ного решения данных задач является практи-ко-ориентированная профессиональная под-готовка соответствующих специалистов. Для организации и проведения практи-ческих занятий по расследованию инциден-тов информационной безопасности в сетях документальной электросвязи и сети Интер-нет как на потоках магистратуры по направ-лению «Информационная безопасность», так и на потоках специалитета «Информацион-ная безопасность телекоммуникационных систем» и «Информационно-аналитические системы безопасности» необходимо созда-ние учебного компьютерного полигона, осна-щенного современными образцами инфор-мационно-аналитических систем безопасно-сти (далее – ИАСБ), такими как IBM I21, МФИ СОФТ «Январь»2, Lampyre3, Gephi4 и др. ИАСБ – это аппаратно-программные ком-плексы для проведения поисково-аналитиче-ской работы, имеющие возможность нака-пливать и анализировать данные о взаимо-действии пользователей информационно-те-1 http://www.ibm.com/software/ products/ru/analysts-notebook2 http://www.mfisoft.ru/direction/sorm/sorm-3/3 http://www.lampyre.io4 http://www.gephi.orgлекоммуникационных сервисов (далее – ИТ-сервисов). Однако подключение учебных ИАСБ к действующему оборудованию опера-торов связи, являющемуся источником ин-формации о взаимодействии пользователей ИТ-сервисов, невозможно в соответствии со ст. 64 Федерального закона «О связи». Также отсутствует возможность применения насто-ящих массивов биллинговой информации в силу того, что такие массивы содержат персо-нальные данные пользователей, а доступ к ним ограничен законодательно. Обзор литературы позволяет сделать вы-вод об отсутствии готовых методов и алгорит-мов генерации массивов данных, отражающих взаимодействие пользователей ИТ-сервисов.Для решения данной проблемы при соз-дании учебного компьютерного полигона по расследованию инцидентов информацион-ной безопасности в учебно-научном центре «Информационная безопасность» ИРИТ-РтФ УрФУ им. первого Президента России Б.Н. Ельцина разработано программное обеспе-чение (далее – ПО). Данное ПО работает в со-ответствии с созданной структурно-параме-трической моделью взаимодействия пользо-вателей в ИТ-сервисах и позволяет синтези-ровать массивы условно-реальных данных. Файлы, содержащие сгенерированные мас-сивы, в дальнейшем загружаются в базу дан-ных ИАСБ для проведения практических за-нятий по решению поисково-аналитических задач. На текущем этапе разработки ПО спо-собно генерировать массивы условно-реаль-ных данных о взаимодействии пользователей социальных сетей и сетей мобильной связи.Static components are synthesized based on the method of forming the structure of social graphs using a composition of models for constructing complex networks with various struc-tural parameters: the Watts-Strogatz model is used for a mobile communication service, and the Barabashi-Albert model is used for a social network service. To preserve the relationship between users in various services, a method is proposed for determining the largest common part of social graphs, based on the mutual differentiation of vertices and the allocation of a partial isomorphism of the compared graphs. When generating vertex attributes, the method of searching for social groups (families) is used, based on the Bron-Kerbosch algorithm for find-ing a click of a given size in a graph.For the synthesis of dynamic components of data arrays that describe the performance of communication events, the mathematical apparatus of color Petri nets is used. An interaction event in information and telecommunication services is represented in the form of a Petri net label, which contains the necessary set of parameters, depending on the type of service. It is proposed to use the structural, event, social and temporal statistical characterist


2019 ◽  
Author(s):  
Jonathan Carney ◽  
David Roundy ◽  
Cory M. Simon

Metal-organic frameworks (MOFs) are modular and adjustable nano-porous materials with applications in gas storage, separations, and sensing. Flexible/dynamic components that respond to adsorbed gas can give MOFs unique or enhanced adsorption properties. Here, we explore the adsorption properties that could be imparted to a MOF by a rotaxane molecular shuttle (RMS) in its pores. In an RMS-MOF, a macrocyclic wheel is mechanically interlocked with a strut. The wheel shuttles between stations on the strut that are also gas adsorption sites. We pose and analyze a simple statistical thermodynamic model of gas adsorption in an RMS-MOF that accounts for (i) wheel/gas competition for sites on the strut and (ii) the entropy endowed by the shuttling wheel. We determine how the amount of gas adsorbed, position of the wheel, and energy change upon adsorption depend on temperature, pressure, and the interactions of the gas/wheel with the stations. Our model reveals that, compared to an ordinary Langmuir material, the chemistry of the RMS-MOF can be tuned to render adsorption more or less temperature-sensitive and release more or less heat upon adsorption. The model also uncovers a non-monotonic relationship between temperature and the position of the wheel if gas out-competes the wheel for its preferable station.


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