Radiation Units, Radiation Exposure, and Absorbed Dose

Author(s):  
Gopal B. Saha
2021 ◽  
Vol 161 (6-7) ◽  
pp. 352-361
Author(s):  
Qi Wang ◽  
Younghyun Lee ◽  
Monica Pujol-Canadell ◽  
Jay R. Perrier ◽  
Lubomir Smilenov ◽  
...  

Detonation of an improvised nuclear device highlights the need to understand the risk of mixed radiation exposure as prompt radiation exposure could produce significant neutron and gamma exposures. Although the neutron component may be a relatively small percentage of the total absorbed dose, the large relative biological effectiveness (RBE) can induce larger biological DNA damage and cell killing. The objective of this study was to use a hematopoietically humanized mouse model to measure chromosomal DNA damage in human lymphocytes 24 h after in vivo exposure to neutrons (0.3 Gy) and X rays (1 Gy). The human dicentric and cytokinesis-block micronucleus assays were performed to measure chromosomal aberrations in human lymphocytes in vivo from the blood and spleen, respectively. The mBAND assay based on fluorescent in situ hybridization labeling was used to detect neutron-induced chromosome 1 inversions in the blood lymphocytes of the neutron-irradiated mice. Cytogenetics endpoints, dicentrics and micronuclei showed that there was no significant difference in yields between the 2 irradiation types at the doses tested, indicating that neutron-induced chromosomal DNA damage in vivo was more biologically effective (RBE ∼3.3) compared to X rays. The mBAND assay, which is considered a specific biomarker of high-LET neutron exposure, confirmed the presence of clustered DNA damage in the neutron-irradiated mice but not in the X-irradiated mice, 24 h after exposure.


Author(s):  
Mary L. Anderson ◽  
Joshua D. Daniel ◽  
Andrei N. Zagrai ◽  
David J. Westpfahl

Piezoelectric sensors are used in many structural health monitoring (SHM) methods to interrogate the condition of the structure to which the sensors are affixed or imbedded. Among SHM methods utilizing thin wafer piezoelectric sensors (PWAS), electro-mechanical impedance monitoring is seen as a promising approach to assess structural condition in the vicinity of a sensor. Using the converse and direct piezoelectric effects, this health monitoring method utilizes mechanical actuation and electric voltage to determine the impedance signature of the structure. If there is damage to the structure, there will be a change in the impedance signature. It is important to discern between actual damage and environmental effects on the piezoelectric ceramic sensors and the structure. If structural health monitoring is to be implemented in space structures on orbit, it is imperative to determine the effects of the extreme space environment on piezoelectric sensors and the structures to which they are affixed. The space environment comprises extreme temperatures, vacuum, atomic oxygen, microgravity, micro-meteoroids and debris, and significant amounts of radiation. Radiation in space comes from three sources: solar events, background cosmic radiation, and trapped particles in the Van Allen Belts. Radiation exposure to structures on orbit will vary significantly depending on the duration of the flight and the altitude and inclination of the orbit. In this contribution, the effect of gamma radiation on piezoelectric ceramic sensors and space grade aluminum is investigated for equivalent gamma radiation exposure to 3-months, six-months, and 1-year on Low Earth Orbit (LEO). An experiment was conducted at White Sands Missile Range, Gamma Radiation Facility using Cobalt-60 as the source of radiation. A free PWAS and a PWAS bonded to a small aluminum beam were exposed to increasing levels of gamma radiation. Impedance data were collected for both sensors after each radiation exposure. The total radiation absorbed dose was 200 kRad (Si) by the end of the experiment. The results show that piezoelectric ceramic material is affected by gamma radiation. Over the course of increasing exposure levels to Cobalt-60, the impedance frequency of the free sensor increased with each absorbed dose. The impedance measurements of the sensor bonded to the aluminum beam reflects structural and sensor’s impedance. The data for this sensor show an increase in impedance amplitude with each level of absorbed dose. The mechanism at work in these impedance changes is suggested and future experimental work is identified. A survey of previous results of radiation exposure of piezoelectric ceramic sensors and aluminum alloys is presented and are compared to previous studies.


2019 ◽  
Vol 213 ◽  
pp. 53-66
Author(s):  
Yago Gonzalez-Velo ◽  
Arshey Patadia ◽  
Hugh J. Barnaby ◽  
Michael N. Kozicki

Chalcogenide-based, programmable metallization cells (PMC) cells have been characterized after exposure to increasing levels of absorbed dose (i.e., ionizing radiation exposure).


Author(s):  
Matthias Port ◽  
Matthäus Majewski ◽  
Michael Abend

Abstract The relation of radiation exposure (dose) with acute radiation syndrome (ARS) depends on many factors. In this overview, we reconsider (1) radiation exposure characteristics (e.g. radiation quality, fractionation, dose rate, partial/total body irradiation) and (2) biological processes (e.g. radiosensitivity, cell cycle dependency, oxygenation) affecting acute health effects after exposure. Furthermore we include evidence from recently published work that examined the relationship of absorbed dose and risk of clinically relevant ARS in persons exposed after a radiation accident. We introduce the concept of radiation-related bioindicators for effect prediction. Bioindicators are considered here to be factors that integrate multiple radiation exposure characteristics and cell- and molecular-based processes to improve clinical prediction in persons with ARS.


Radiology ◽  
1972 ◽  
Vol 104 (1) ◽  
pp. 197-200 ◽  
Author(s):  
A. G. Haus ◽  
K. Strubler ◽  
J. E. Marks

2019 ◽  
Vol 822 ◽  
pp. 355-361
Author(s):  
M.S. Lisanevich ◽  
Rezeda Yu. Galimzyanova ◽  
Elvina P. Rakhmatullina ◽  
Yu.N. Khakimullin ◽  
Ildar N. Musin ◽  
...  

While producing polymers as well as during their processing, a certain amount of stabilizers is introduced into the product, which should ensure polymer properties saving during processing and those of polymer products during storage and operation. However, in cases where medical products based on polypropylene are subjected to radiation sterilization, there are not enough stabilizers in it to save their characteristics during operation. In this regard, we made an assessment of the influence of processing conditions on the properties of polypropylene with a different set of stabilizers in the manufacture of products based on it, in order to assess the degree of influence of each technological operation, including the effects of ionizing radiation during sterilization. Processing and radiation exposure are shown to affect the properties of polypropylene. Nevertheless, the effect of ionizing radiation with an absorbed dose of 40-60 kGy exceeds the negative effect of thermo-oxidative breakdown greatly during the extrusion of PP. Polypropylene containing organophosphorus stabilizers (brand PP 1562R) is more susceptible to breakdown. This is indicated by low values of oxidation induction time, breakdown initial temperature, as well as high values of MFI after exposure to electron radiation. PP brand PP H350FF/1 whose stabilizing complex contains phenol-phosphite antioxidants is more resistant to breakdown during processing and sterilization. For both brands under study, it is apparently necessary to increase the content of stabilizing additives in order to save the properties at the level of the original unexposed material.


2003 ◽  
Vol 59 (5) ◽  
pp. 640-649 ◽  
Author(s):  
TAKAYUKI HASEGAWA ◽  
MASAYUKI KOIZUMI ◽  
TOMO FURUKAWA

2017 ◽  
Vol 17 (2) ◽  
pp. 244-252
Author(s):  
K. W. Cheung ◽  
K. K. Sang ◽  
H. I. Lam ◽  
W. M. Chan ◽  
P. M. Wu ◽  
...  

AbstractAimThe purpose of this study was to investigate whether significant difference exists on radiation dose delivered to organs at risks in megavoltage computed tomography (MVCT) verification using three predefined scanning modes, namely fine (2 mm), normal (4 mm) and coarse (6 mm). This will provide information for the imaging protocol of tomotherapy for the left breast.Materials and methodsOrgan doses were measured using thermoluminescent dosimeters (TLD-100) placed within a female Rando phantom for MVCT imaging. Kruskal–Wallis test was conducted with p<0·05 to evaluate the significant difference between the three MVCT scanning modes.ResultsStatistically significant difference existed in organ absorbed dose between different scan mode selections (p<0·001). Relative to the normal scan selection (4 mm), the absorbed dose to the organs of interests can be scaled down by 0·7 and scaled up by 2·1 for coarse (6 mm) and fine scans (2 mm) respectively.ConclusionsOptimisation of imaging protocols is of paramount importance to keep the radiation exposure ‘as low as reasonably achievable’. The recommendation of undergoing daily coarse mode for MVCT verification in breast tomotherapy not only mitigates the radiation exposure to normal tissues, but also trims the scan-acquisition time.


2018 ◽  
Vol 3 (3) ◽  
pp. 8
Author(s):  
Makarenko E.S ◽  
Oudalova A.A. ◽  
Geras'kin S.A.

The morphometric indices of needles were investigated in chronically irradiated Scots pine (Pinus sylvestris L.) populations from territories that were heavily contaminated by radionuclides as a result of the Chernobyl Nuclear Power Plant accident. The variability in needle weight and length, as well as the fluctuating asymmetry indices were studied in seven contaminated and two reference populations of Scots pine in 2011, 2013, 2014 and 2016. The weight of needles in the contaminated populations was significantly higher than in the reference population; however, the dependence of this index on the level of radiation exposure was not revealed in the studied range of doses. The length of needles differed significantly from the references populations. The effect changed from decreasing to increasing in various years of observation; however, in 2016 this index decreased with the dose rate of β-radiation. The index of fluctuating asymmetry in needle length was significantly higher than at the reference sites during three years and correlated to the estimated annual absorbed dose in 2011 and 2013. No relationship was revealed between the asymmetry in weight of paired needles and radiation exposure.


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