Prolonged Refractory High Fever

Author(s):  
Ross Petty ◽  
Farhad Salehzadeh
Keyword(s):  
BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e049069
Author(s):  
Atsushi Miyawaki ◽  
Takahiro Tabuchi ◽  
Yasutake Tomata ◽  
Yusuke Tsugawa

ObjectiveTo investigate the association between participation in government subsidies for domestic travel (subsidise up to 50% of all travel expenses) introduced nationally in Japan on 22 July 2020 and the incidence of symptoms indicative of COVID-19 infections.DesignCross-sectional analysis of nationally representative survey data.SettingInternet survey conducted between 25 August and 30 September 2020 in Japan. Sampling weights were used to calculate national estimates.Participants25 482 survey respondents (50.3% (12 809) women; mean (SD) age, 48.8 (17.4) years).Main outcome measuresIncidence rate of five symptoms indicative of the COVID-19 infection (high fever, sore throat, cough, headache, and smell and taste disorder) within the past month of the survey, after adjustment for characteristics of individuals and prefecture fixed effects (effectively comparing individuals living in the same prefecture).ResultsAt the time of the survey, 3289 (12.9%) participated in the subsidy programme. After adjusting for potential confounders, we found that participants in the subsidy programme exhibited higher incidence of high fever (adjusted rate, 4.7% for participants vs 3.7% for non-participants; adjusted OR (aOR) 1.83; 95% CI 1.34 to 2.48; p<0.001), sore throat (19.8% vs 11.3%; aOR 2.09; 95% CI 1.37 to 3.19; p=0.002), cough (19.0% vs 11.3%; aOR 1.96; 95% CI 1.26 to 3.01; p=0.008), headache (29.2% vs 25.5%; aOR 1.24; 95% CI 1.08 to 1.44; p=0.006) and smell and taste disorder (2.6% vs 1.8%; aOR 1.98; 95% CI 1.15 to 3.40; p=0.01) compared with non-participants. These findings remained qualitatively unaffected by additional adjustment for the use of 17 preventative measures (eg, social distancing, wearing masks and handwashing) and fear against the COVID-19 infection.ConclusionsThe participation of the government subsidy programme for domestic travel was associated with a higher probability of exhibiting symptoms indicative of the COVID-19 infection.


2005 ◽  
Vol 164 (7) ◽  
pp. 453-454 ◽  
Author(s):  
Banu Acar ◽  
Z. Birsin Özcakar ◽  
Selcuk Yüksel ◽  
Tugba Pekacar ◽  
Mesiha Ekim ◽  
...  
Keyword(s):  

PEDIATRICS ◽  
1968 ◽  
Vol 41 (5) ◽  
pp. 954-954
Author(s):  
Jonathan Binns ◽  
T. E. C.

Few letters written by either English or American eighteenth century physicians about the treatment of sick infants have come down to us. Most of our information about the care of such infants comes from the handful of pediatric texts published in that century. The letter below, written by Dr. Jonathan Binns in 1772 to the parents of his ailing 11-month-old nephew, starkly points out the therapeutic limitations of pediatric practice two centuries ago. The infant about whom this letter was written had a high fever and was lethargic. So far as I can judge from little Tommy's case, I think it proper that he continues sucking. If he would take any other sustenance I would advise you to give him a little red or white wine every day. He may, at different times, take about one Glass; but be very cautious of it if his eyes be somewhat sore and inflamed. Red port is preferable to white, provided he is sufficiently open in his belly. You might also try him to take once a day a few spoonfuls of weak broth made of the lean part of beef or mutton.1


2015 ◽  
Vol 14 (3) ◽  
pp. 299-301
Author(s):  
Suman Das ◽  
Dilip Kumar Paul ◽  
Anish Chatterjee ◽  
Sumantra Raut

A 28 days old neonate presented with high fever, abdominal distension, poor feeding and lethargy. Sepsis screen was positive; ultrasound and computed tomography of the abdomen demonstrated a multiloculated hepatic abcess in the right lobe of the liver. The baby was treated with intravenous antibiotics for 6 weeks and percutaneous aspiration of the abcess, resulting in excellent recovery.Bangladesh Journal of Medical Science Vol.14(3) 2015 p.299-301


2002 ◽  
Vol 29 (2) ◽  
pp. 115-116 ◽  
Author(s):  
Yasuhiro Horiuchi ◽  
Masahiro Toyama ◽  
Kazuto Ikezawa
Keyword(s):  

2014 ◽  
Vol 142 (1-2) ◽  
pp. 79-82 ◽  
Author(s):  
Bogdan Arsic ◽  
Ana Gligic ◽  
Elizabeta Ristanovic ◽  
Branislav Lako ◽  
Aleksandar Potkonjak ◽  
...  

Introduction. Ehrlichiosis is a bacterial zoonosis transmitted by hematophagous arthropods - ticks. In humans, it occurs as monocytic, granulocytic, and ewingii ehrlichiosis. Pathological process is based on parasitic presence of Ehrlichia organisms within peripheral blood cells - monocytes and granulocytes. Case Outline. Fifty-two year old patient was admitted to hospital due to high fever of over 40?C that lasted two days, accompanied with chills, muscle aches, malaise, loss of appetite, headache, confusion, breathing difficulties, and mild dry cough. The history suggested tick bite that occurred seven days before the onset of disease. Doxycycline was introduced and administered for 14 days, causing the disease to subside. Indirect immunofluorescence assay was used to analyze three serum samples obtained from this patient for Ehrlichia chaffeensis antibodies, and peripheral blood smear was evaluated for the presence of Ehrlichia and Ehrlichia aggregation into morulae. Conclusion. Ehrlichiosis should be considered in each case where there is a history of tick bite together with the clinical picture (high fever, chills, muscle aches, headache, generalized weakness and malaise, and possible maculopapular rash). The presence of Ehrlichia chaffeensis antibodies was confirmed in a patient with the history of tick bite, appropriate clinical picture and indirect immunofluorescence assay. This confirmed the presence of human monocytotropic ehrlichiosis, a disease that is uncommonly identified in our country.


2006 ◽  
Vol 1 (1) ◽  
pp. 42
Author(s):  
Ajeng Tias Endarti ◽  
Ratna Djuwita

Jumlah kasus flu burung pada manusia meningkat sangat pesat. Studi ini bertujuan untuk mengetahui gambaran epidemiologi penyakit flu burung (Avian Influenza / AI) pada kejadian luar biasa di 5 provinsi Indonesia in 2005-2006. Studi ini mengunakan sumber data sekunder data surveilens, sub direktorat Surveilens, Depkes RI, pada periode Juli 2005-2006. Dari 28 kasus konfirmasi ditemukan banyak pada pria (57.1%). Sekitar 89.3% kasus memperlihatkan gejala demam tinggi (≥ 38°C), batuk dan masalah pernapasan dan sekitar 80% diantaranya meninggal dunia. Gejala tersebut mengindikasikan kerusakan jaringan paru-paru pada tubuh penderi- ta. Berdasarkan laporan hasil pemeriksaan laboratorium, terlihat bahwa 60.7% penderita mengalami penurunan kadar leukosit (leucopenia) dan 46.4% penurunan kadar trombosit (thrombocytopenia). Laju fatalitas kasus yang telah mendapat pengobatan Tamiflu mencapai 66.7%. Sekitar 53.6% mempunyai riwayat kontak den- gan ayam dan bebek. Banyak kasus terjadi pada kelompok dewasa (> 18 years) dengan frekuensi 57.1%. Sebaliknya, laju respon untuk kasus, terlihat sekitar 64, 3 % mengalami pengobatan yg terlambat. Rata-rata semua kasus konfirmasi di Indonesia pada July 2005 - February 2006 adalah 3.5 kasus /bulan. Kasus-kasus tersebut terjadi dalam wilayah yang mengalami KLB pada binatang ternak. Sampai 28 Februari, 2006, KLB telah ditemukan di lima provinsi yang meliputi: Lampung (10.72%), DKI Jakarta (32.14), Jawa Barat (39.29%), Banten (14.28%) and Jawa Tengah (3.57%). Dapat disimpulkan bahwa kasus lebih sering ditemukan pada pria dewasa dan pada orang yang lebih terpapar dengan faktor risiko. Kasus-kasus tersebut menampilkan gejala demam tinggi, batuk, masalah-masalah pernapasan leukopenia and trombositopenia. Selain itu, angka dan keefektifan ditemukan rendah. Kasus-kasus tersebut terjadi terutama pada musim hujan dan pada wilayah yang sebelumnya mengalami KLB pada binatang seperti ayam dan bebek.Kata kunci: Avian flu, epidemiologi diskriptif , kejadian luar biasa, IndonesiaAbstractThe number of Human Avian Influenza in Indonesia increasing tremendously. The research is intended to identify the epidemiological description of Avian Influenza’s (AI) outbreaks within five provinces in Indonesia in 2005-2006. The research conducted descriptively using AI surveillance data from July 2005 up until February 2006. The data gained from the Surveillance sub-directorate Ministry of Health of Indonesia. From 28 confirmed AI cases, many occurred to male (57.14%) since Approximately 89.29% of the cases showed symptom of high fever (≥ 38° C), cough and respiratory problems and 80 % of such cases resulted to deceased for the victim. The symptoms indicated that severe destruction of tissue (pneumonia) occurred in the victim body. Based on laboratory’s report, it shows 60.71% of leucope- nia and 46.43% of thrombocytopenia cases. The death rate for the cases that have Tamiflu treatment reached 66.67%. 53.57% of the case reveals the victims’ high interactions with chicken and duck as the risk factor (avian). Many cases occurred to adult (> 18 years) with a hit rate of 57.14%. On the other hand, the response rate for the cases shows that 64.29 show late treatment of the cases. The average of confirmed AI cases in Indonesia from July 2005 to February 2006 is 3.5 cases/months. The cases occurred within the area that has AI outbreak to the animal. Up until February 28, 2006, the AI outbreaks have been found within five provinces, they are: Lampung (10.72%), DKI Jakarta (32.14), West Java (39.29%), Banten (14.28%) and Central Java (3.57%). It can be concluded that the cases inflicted more to adult male and to those people who interact more with the risk factor. The cases reveal symptoms such as high fever, cough, respiratory problems, leucopenia and thrombocytopenia. Furthermore the cases response rates and Tamiflu effectively were low. The cases occurred mainly in rainy seasons and to the areas those priories have AI outbreaks to the animals such as chickens or ducks.Key words: Avian flu, descriptive epidemiology , outbreak, Indonesia


1996 ◽  
Vol 6 (2) ◽  
pp. 182-187
Author(s):  
Yaman Tokat ◽  
Adam Uslu ◽  
Abdülkadir Ünsal ◽  
Ercan Ok ◽  
Murat Kılıç ◽  
...  

2020 ◽  
Author(s):  
Pardis Tabaee Damavandi

The UK government has recently announced how the Covid19 virus has mutated, causing a surge in the cases in Essex, and other parts of England, however, this mutation had already been observed later in the Summer 2020 in a population of Minks and in Denmark. A “prescient” analysis of the mutation is explored in this short paper. Potential symptoms may involve not just high fever but more infections due to major cough expulsion from increased hydrosolubility of the viral proteins.


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