scholarly journals Management of Scars in Skin of Color

2020 ◽  
pp. 371-377
Author(s):  
Huidi Tchero
Keyword(s):  
Randomized Clinical Trials ◽  
Surgical Excision ◽  
Treatment Method ◽  
Treatment Modalities ◽  
Hypertrophic Scars ◽  
Strategic Assessment ◽  
Wound Healing Response ◽  
Intralesional Steroid ◽  
Silicone Gel Sheet

AbstractKeloids and hypertrophic scars are abnormal scars, produced by an odd wound-healing response to trauma with a higher incidence in pigmented skin patients. They could be painful or itchy, producing functional and/or cosmetic disability. This chapter focuses on defining scars especially in pigmented skin and the different methods for treating keloids that have been investigated in the literature. Up to the present time, the ideal treatment method has not been defined, although numerous modalities have been designated. We will represent the variances among different scar types and their management methods, concentrating on their indications, modes of action, uses, safety, and efficiency of the following therapies: intralesional steroid, injections of silicone gel/sheet, radiotherapy, photodynamic therapy, electrical stimulation, surgical excision and adjuvant therapy, and cryosurgery. Combination therapies have also shown some value. Still, there is a shortage of randomized clinical trials (RCTs) evaluating such treatment modalities. Management of scar in pigmented (colored) skin is clinically challenging. Therefore, strategic assessment and targeted therapy with focus on deterring recurrence are most needed. The quality of evidence is crucial to select efficient treatments for patients with colored skin, presenting with keloid.

scholarly journals Laser management of hypertrophic burn scars: a comprehensive review

2020 ◽  
Vol 8 ◽  
Author(s):  
Kevin M Klifto ◽  
Mohammed Asif ◽  
C Scott Hultman
Keyword(s):  
Recovery Period ◽  
Surgical Excision ◽  
Postoperative Recovery ◽  
Restricted Range ◽  
Hypertrophic Scars ◽  
Laser Technology ◽  
Associated Symptoms ◽  
Different Types ◽  
Risk Approach

Abstract Hypertrophic scars often develop following burn-related injuries. These scars can be cosmetically unappealing, but associated symptoms of pruritus, pain and restricted range of motion can impair a person’s quality of life. Laser and light therapies offer a minimally invasive, low-risk approach to treatment, with a short postoperative recovery period. As laser technology developed, studies have shown decreased scar thickness, neuropathic pain and need for surgical excision, as well as improved scar pigmentation, erythema, pliability, texture, height and pruritus. In this review, we present the evolution of laser therapy for hypertrophic burn scars, how different types of lasers work, indications, perioperative considerations and guidelines for practice management.

scholarly journals Intralesional steroid induced hypopigmentation- a case report

2017 ◽  
Vol 3 (4) ◽  
pp. 108
Author(s):  
Shailendra Vikram Jitendra Singh ◽  
Romita Bachaspatimayum ◽  
Subhalakshmi Devi Akham ◽  
Rita Devi Sanjenbam
Keyword(s):  
Case Report ◽  
Adverse Effects ◽  
Male Patient ◽  
Steroid Therapy ◽  
Surgical Excision ◽  
Treatment Modalities ◽  
Benign Condition ◽  
Left Wrist ◽  
Intralesional Steroid

<p class="abstract">Ganglions are tense, smooth, fluctuant, cystic transilluminant swellings commonly <span lang="EN-IN">found on the dorsum of the wrist, at the scapholunate articulation. Treatment modalities include aspiration, intralesional corticosteroids, surgical excision, etc. Hypopigmentation is one of the adverse effects associated with intralesional steroid therapy</span>.  <span lang="EN-IN">Here, we report </span><span lang="EN-IN">a 21 years old male patient who came with an asymptomatic whitish patch on the left wrist after receiving triaminolone 40 mg injection at the same site for a ganglion.</span><span lang="EN-IN">Case is being reported so as to create awareness of this benign condition amongst the treating physicians or surgeons.</span></p>

scholarly journals Hemorrhoids and quality of life: “… two things incompatible”?

2021 ◽  
pp. 74-79
Author(s):  
M. V. Abritsova ◽  
A. M. Bogomazov ◽  
E. B. Golovko ◽  
E. A. Zagriadskii
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Social Life ◽  
Well Being ◽  
Treatment Method ◽  
Social Adaptation ◽  
Treatment Modalities ◽  
Surgical Approaches ◽  
Surgical Methods

Hemorrhoids is one of the most common diseases in human. According to the latest data for 2017, the prevalence rates of hemorrhoids per 100 000 population in Russia are 410,3 in adults, 26.7 in children aged 15 to 17 years and 4,0 in children under 14 years old. Quality of life (QoL) is an important non-specific subjective parameter of well-being, representing an integrative characteristic of the physical, psychological, social and emotional status of the patient. Despite the high prevalence of hemorrhoids and the variety of modern methods of surgical treatment, there are very few studies addressing the QoL in this category of patients. There are significant differences between the patient and the Coloproctologist in the perception of HD, which, possibly, can lead to the hypertrophy of indications for surgical treatment. Understanding the effect of HD on social life and the concept of the well-being of a particular patient can help the doctor choose between conservative and surgical approaches in the treatment of hemorrhoids. On the other hand, due to the excessive shyness and mentality in our country, patients with HD tend to adapt to their disease, which leads to later seeking medical help and suboptimal efficacy of conservative therapy and minimally invasive surgical methods.This review presents the first Russian multicenter observational program EQUALISER (impact of different trEatment modalities on QUAlity of life of the patientS with acute and chronic hEmorRhoid disease) aimed at assessing the QoL of patients with HD, as well as the effect of the treatment method and types of surgical treatment on the social adaptation of the population.

Refractory Ascites: Treatment and Complications Utilizing Peritoneovenous (Denver) Shunt

2017 ◽  
Vol 01 (04) ◽  
pp. 259-264
Author(s):  
Parvaneh Shadkam-Farrokhi ◽  
Edward Lee
Keyword(s):  
Symptomatic Relief ◽  
Treatment Method ◽  
Treatment Modalities ◽  
Refractory Ascites ◽  
Medical Providers ◽  
Standard Medical Therapy ◽  
Portosystemic Shunts ◽  
Surgical Methods ◽  
Peritoneovenous Shunts

AbstractIntractable ascites has long been an antagonizing problem for patients and medical providers. It is debilitating and frequently cannot be prevented by standard medical therapy. Ascites is primarily managed with salt restrictions, diuretics, and repeated paracentesis for symptomatic relief. However, 10% of patients become refractory to this first line of treatment. Several surgical methods such as the insertion of peritoneovenous shunts and transjugular intrahepatic portosystemic shunts have become popularized treatment modalities for the control of refractory ascites. Nevertheless, controversy resides over what is the best treatment method for the improvement in patients' quality of life and survival rate. We herein explore the different medical and surgical methods available for the control of refractory ascites with a focus on the advantages and complications associated with the usage of Denver peritoneovenous shunts.

scholarly journals Simple device to determine the pressure applied by pressure clips for the treatment of earlobe keloids

2015 ◽  
Vol 48 (03) ◽  
pp. 293-296 ◽  
Author(s):  
Aashish Sasidharan ◽  
Ann David ◽  
Amish Gohil ◽  
Ashish Kumar Gupta
Keyword(s):  
Steroid Injection ◽  
Surgical Excision ◽  
Compression Therapy ◽  
Treatment Modalities ◽  
Slight Variation ◽  
Simple Method ◽  
Pressure Therapy ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection ◽  
Common Problems

ABSTRACT Background: Keloids of the ear are common problems. Various treatment modalities are available for the treatment of ear keloids. Surgical excision with intralesional steroid injection along with compression therapy has the least recurrence rate. Various types of devices are available for pressure therapy. Pressure applied by these devices is uncontrolled and is associated with the risk of pressure necrosis. We describe here a simple and easy to use device to measure pressure applied by these clips for better outcome. Objectives: To devise a simple method to measure the pressure applied by various pressure clips used in ear keloid pressure therapy. Materials and Methods: By using a force sensitive resistor (FSR), the pressure applied gets converted into voltage using electrical wires, resistors, capacitors, converter, amplifier, diode, nine-volt (9V) cadmium battery and the voltage is measured using a multimeter. The measured voltage is then converted into pressure using pressure voltage graph that depicts the actual pressure applied by the pressure clip. Results: The pressure applied by different clips was variable. The spring clips were adjustable by slight variation in the design whereas the pressure applied by binder clips and magnet discs was not adjustable. Conclusion: The uncontrolled/suboptimal pressure applied by certain pressure clips can be monitored to provide optimal pressure therapy in ear keloid for better outcome.

scholarly journals Treatment of Hailey–Hailey disease with narrowband phototherapy and acitretin: A case report

2019 ◽  
Vol 7 ◽  
pp. 2050313X1984522 ◽  
Author(s):  
Tatiana Lapa ◽  
Maksym Breslavets
Keyword(s):  
Autosomal Dominant ◽  
Botulinum Toxin A ◽  
Surgical Excision ◽  
Ultraviolet B ◽  
Treatment Modalities ◽  
Topical Steroids ◽  
Oral Antibiotics ◽  
Multiple Treatment ◽  
Chronic Course

The Hailey–Hailey disease, or familial benign chronic pemphigus, is an autosomal dominant genodermatosis affecting mainly intertriginous areas. It manifests itself in painful blisters, erosions, and cracks and has a chronic course with frequent flares, significantly impacting patients’ quality of life. Presently, there is no cure, but multiple treatment modalities are available. Most evidence supports treatment with topical steroids and antimicrobials. Treatment of recalcitrant disease has been shown to benefit from the addition of oral antibiotics, Naltrexone, systemic retinoids, botulinum toxin A injections, laser treatment, and surgical excision. We describe a case of refractory Hailey–Hailey disease for which most of the abovementioned options failed, but which demonstrated significant improvement following a combination of oral acitretin and narrowband ultraviolet-B phototherapy. To achieve remission, the patient received 30 sessions three times per week with the increment of 20 mJ/cm2 per session and oral acitretin 25 mg PO daily.

Non-Vitamin K Antagonist Oral Anticoagulants in Pulmonary Embolism: An Overview of Systematic Reviews

2020 ◽  
Vol 26 (23) ◽  
pp. 2686-2691 ◽  
Author(s):  
Ioannis Doundoulakis ◽  
Christina Antza ◽  
Haralambos Karvounis ◽  
George Giannakoulas
Keyword(s):  
Pulmonary Embolism ◽  
Vitamin K ◽  
Systematic Reviews ◽  
Methodological Quality ◽  
Randomized Clinical Trials ◽  
Oral Anticoagulants ◽  
Vitamin K Antagonist ◽  
Language Restriction ◽  
Overview Of Systematic Reviews

Background: Anticoagulation in patients with pulmonary embolism. Objective: To identify how non-vitamin K antagonist oral anticoagulants are associated with multiple outcomes in patients with pulmonary embolism. Methods: We performed a systematic search of systematic reviews via multiple electronic databases from inception to August 19th, 2019, without language restriction. Two authors independently extracted data and assessed the methodological quality of the included systematic reviews using the ROBIS tool. Results: We found twelve systematic reviews. Eleven SRs collected their data from randomized clinical trials and one from observational studies. All the included studies were published between 2014 and 2019 in English. The methodological quality of the 12 systematic reviews was low to high. None of the systematic reviews, which are included in our overview of systematic reviews, has evaluated the overall quality of evidence outcome using the Grading of Recommendations Assessments, Development and Evaluation (GRADE) approach. Conclusion: This is the first effort to summarize evidence about non-vitamin K antagonist oral anticoagulants in an overview of systematic reviews focusing exclusively on patients with pulmonary embolism. The evidence suggests that the non-vitamin K antagonist oral anticoagulants seem to be more effective and safer than a dualdrug approach with LMWH- VKA.

Role of Erlotinib in Influencing the Quality of Life of Cancer Patients

2020 ◽  
Vol 07 ◽  
Author(s):  
Deepika Purohit ◽  
Parijat Pandey
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Kinase Inhibitors ◽  
Treatment Modalities ◽  
Pancreatic Cancers ◽  
Review Reports ◽  
Causes Of Deaths

Background:: Cancer is one of the significant causes of morbidity and mortality in patients globally. Lung cancer, among other cancers, remains to be one of the principal causes of deaths in both men and women. The most common type of lung cancer is the non-small-cell lung cancer (NSCLC). Apart from lung cancer, pancreatic cancer is also one of the common cancers currently. Objective:: The assessment of QoL in erlotinib-treated patients can also prove to be very useful in the establishment of this drug as the main treatment option for the patients with pancreatic and lung cancer. Methods:: Therapies that target EGFR-mediated signalling are the latest keystones for treating these two types of cancers. They comprise of two main treatment modalities: firstly, against the extracellular fields, that include monoclonal antibodies and secondly, mechanisms that create interferences in the signalling pathways, primarily the small molecule tyrosine kinase inhibitors. Results:: Quality of life (QoL) is one of the key advantages in erlotinib therapy over chemotherapy. Conclusion:: The present review reports the role of erlotinib in improving the quality of life of cancer patients especially in NSCLC and pancreatic cancers. The studies or trials establishing the relations between erlotinib and QoL are discussed in detail in this review.

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