Radial club hand managed with ulnar osteotomy and centralization of hand: a case report and review

<p>Radial club hand also called radial longitudinal deficiency or radial dyspasia is a preaxial longitudinal failure of formation. As the defect is preaxial it is often associated with thumb hypoplasia or anomaly of the radial aspect of the carpus. It is diagnosed clinically and on X-rays. It is frequently syndromic so it is a must to look for associated congenital anomalies by doing a through clinical examination. The frequency of this anomaly is between 1:50000 to 1:100000 live births. The incidence of all radial ray-deficient limbs, including hypoplastic thumbs alone, is approximately 1:30000. The radial deficiency is bilateral in 50% of the cases and the male:female is 3:2. It includes a wide spectrum of disorders that encompass an absent thumb or thumb hypoplasia, a thin first metacarpal and an absent radius. We report here a 1.5 years old child with isolated type IV radial club hand without any restricted range of motion in elbow managed with osteotomy of ulna and centralization of hand.</p>

Sundering of earthworms by the Fairy Pitta (Pitta nympha): an unexplored strategy of prey preparation for brood provisioning by avian vermivores

Ecological specialists utilize a restricted range of resources and have evolved adaptations to exploit their specialized resources. For example, avian insectivores that feed nestlings with grasshoppers, beetles, or moths perform insect prey preparation before feeding nestlings so that the nestlings are able to swallow the prey. This behavior is generally not expected for soft prey such as earthworms. However, an overview of photographic evidence available online suggested that earthworms are sundered by parents before bringing the prey to the nestlings in a range of species from several families of vermivores worldwide. Reports on the provisioning of nestlings by the vermivores are relatively scant and no report on earthworm sundering has been published. We studied earthworm sundering performed by parents provisioning their broods at four nests of the Fairy Pitta in Korea. The birds sundered earthworms more often when nestlings were smaller and when the earthworm was longer. This is the first quantitative description of earthworm sundering in avian vermivores. We present and evaluate four hypotheses for the function of sundering: provisioning of small nestlings, decreased detectability, hunting multiple prey, and transport of prey. Among these, provisioning of small nestlings seems the most feasible explanation of sundering by the Fairy Pitta as sundering the earthworm allows parents to efficiently provision the younger/smaller nestlings who would have difficulties swallowing unsundered earthworms. This specialized prey preparation technique of vermivores suggests a tight adaptive match between their parental behaviors and their diet (vermivory).

Review of Extraosseous Applications of Thermal Ablation in the Treatment of Moderate to Severe Large Joint Osteoarthritis

Osteoarthritis (OA) is the most common joint disease worldwide, leading to significant pain, restricted range of motion, and disability. A gap exists between short- and long-term symptom-relieving therapies. Although arthroplasty is an effective treatment for symptomatic end-stage disease, most patients ultimately do not receive a joint replacement due to suboptimal surgical qualifications, comorbidities, or an aversion to surgery. The lack of additional treatment options in this setting makes opioid agonists a commonly used pharmacologic agent, contributing to the addiction epidemic that greatly afflicts our communities. Cooled radiofrequency ablation (CRFA) has arisen as a treatment modality in the setting of moderate to severe OA among patients refractory to conservative management, generally showing greater efficacy compared with other existing strategies. This review focuses on the benefits of CRFA and its technical feasibility as a management option among patients experiencing debilitating large joint OA with limited clinical options.

Forecasting criteria for sulphide PGE-copper-nickel deposits of the Noril’sk province (In English)

Research subject. World-class sulphide platinum-group-element (PGE)-Cu-Ni deposits occur within the Noril’sk-Talnakh region of northern Siberia, Russia. The signifcance of these deposits presents opportunities to determine the most effective approaches for the search of similar deposits using commercial PGE-Cu-Ni deposit examples. Materials and methods. Petrological and geochemical analysis of the ultramafc-mafc intrusions of the Noril’sk province ranks them into three types in terms of sulphide mineralization style and economic signifcance: 1) economic intrusions containing unique and large sulphide PGE-Cu-Ni deposits (Oktyabr’sk, Talnakh and Noril’sk-1); 2) subeconomic intrusions that contain small- to medium-sized Cu-Ni sulphide deposits, and medium-sized to large PGE deposits (Chernogorsk, Zub-Marksheider, Vologochan, etc.); 3) uneconomic intrusions that contain low-grade disseminated Cu-Ni ores with ≈0.2 wt % of Cu and Ni, and low Cr and PGE (Nizhny Talnakh, Zelyonaya Griva, etc.). Results and conclusions. Principal sources used in exploration for rich sulphide PGE-Cu-Ni ores include structural, magmatic, stratigraphic-lithological, geochemical, mineralogical, metamorphic and some others. Based on an analysis of isotope-geochemical data, new indicators for locating sulphide PGE-Cu-Ni mineralization are suggested. A restricted range of S-isotope values, and a negative trend for coupled S-Cu isotope compositions can be employed as useful guides to assess the economic potential of a PGE-Cu-Ni sulphide deposit. It is proposed that the Chernogorsk ultramafc-mafc intrusion of the Noril’sk province is the most promising target in a search for rich PGE-Cu-Ni ores. It is suggested that the previously known mineralogical-geochemical and novel isotope-geochemical characteristics of sulphide and silicate minerals are important indicators in assessing the potential ore content of ultramafc-mafc intrusions of the Noril’sk province.

Slow-burning instabilities of Dufort-Frankel finite differencing

DuFort–Frankel averaging is a tactic to stabilize Richardson’s unstable three-level leapfrog timestepping scheme. By including the next time level in the right-hand-side evaluation, it is implicit, but it can be rearranged to give an explicit updating formula, thus apparently giving the best of both worlds. Textbooks prove unconditional stability for the heat equation, and extensive use on a variety of advection–diffusion equations has produced many useful results. Nonetheless, for some problems the scheme can fail in an interesting and surprising way, leading to instability at very long times. An analysis for a simple problem involving a pair of evolution equations that describe the spread of a rabies epidemic gives insight into how this occurs. An even simpler modified diffusion equation suffers from the same instability. Finally, the rabies problem is revisited and a stable method is found for a restricted range of parameter values, although no prescriptive recipe is known which selects this particular choice. doi:10.1017/S1446181121000043

Sunflower Theorems in Monotone Circuit Complexity

Alexander Razborov (1985) developed the approximation method to obtain lower bounds on the size of monotone circuits deciding if a graph contains a clique. Given a "small" circuit, this technique consists in finding a monotone Boolean function which approximates the circuit in a distribution of interest, but makes computation errors in that same distribution. To prove that such a function is indeed a good approximation, Razborov used the sunflower lemma of Erd\H{o}s and Rado (1960). This technique was improved by Alon and Boppana (1987) to show lower bounds for a larger class of monotone computational problems. In that same work, the authors also improved the result of Razborov for the clique problem, using a relaxed variant of sunflowers. More recently, Rossman (2010) developed another variant of sunflowers, now called "robust sunflowers", to obtain lower bounds for the clique problem in random graphs. In the following years, the concept of robust sunflowers found applications in many areas of computational complexity, such as DNF sparsification, randomness extractors and lifting theorems. Even more recent was the breakthrough result of Alweiss, Lovett, Wu and Zhang (2020), which improved Rossman's bound on the size of hypergraphs without robust sunflowers. This result was employed to obtain a significant progress on the sunflower conjecture. In this work, we will show how the recent progress in sunflower theorems can be applied to improve monotone circuit lower bounds. In particular, we will show the best monotone circuit lower bound obtained up to now, breaking a 20-year old record of Harnik and Raz (2000). We will also improve the lower bound of Alon and Boppana for the clique function in a slightly more restricted range of clique sizes. Our exposition is self-contained. These results were obtained in a collaboration with Benjamin Rossman and Mrinal Kumar.

Home range and movements of San Joaquin antelope squirrels in the San Joaquin Desert of California

The San Joaquin antelope squirrel (Ammospermophilus nelsoni) is one of five species in the genus and has the most restricted range of the four mainland antelope squirrels, occurring only in the San Joaquin Desert of California. Despite being state-listed as Threatened since 1980, few studies have been conducted on A. nelsoni, especially ecological studies, which hampers recovery efforts. We conducted a radio-telemetry study in 2002 of 19 males on the Lokern Natural Area in the southwestern portion of the San Joaquin Desert. Based on 100% Minimum Convex Polygons (MCP), home ranges varied from 1.25–14.5 ha with a mean of 5.93 ha (± 0.90 standard error). The average daily distance traveled by these 19 males was 128.5 m (range, 71.4–224.5) and the average greatest distance travelled in a day was 313.0 m, with some traveling > 0.5 km. Our data are useful to further refine the estimates of home range and movements of this neglected protected species, but in the future, better home range studies are needed that span multiple years, include both sexes, and occur at sites across its range.