scholarly journals Run for Your Life – An Integrated Virtual Tissue Platform for Incorporating Exercise Oncology into Immunotherapy

Author(s):  
Josua Aponte-Serrano ◽  
Amit Hagar
Keyword(s):  
2021 ◽  
Author(s):  
Melanie Potiaumpai ◽  
Shawna E. Doerksen ◽  
Vernon M. Chinchilli ◽  
Hongke Wu ◽  
Li Wang ◽  
...  

2020 ◽  
pp. 87-110
Author(s):  
Ciaran M. Fairman ◽  
Daniel A. Galvão
Keyword(s):  

2020 ◽  
pp. 429-433
Author(s):  
Kathryn H. Schmitz
Keyword(s):  

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0120996 ◽  
Author(s):  
Charlotte N. Steins Bisschop ◽  
Kerry S. Courneya ◽  
Miranda J. Velthuis ◽  
Evelyn M. Monninkhof ◽  
Lee W. Jones ◽  
...  

2020 ◽  
Vol 52 (2) ◽  
pp. 315-322 ◽  
Author(s):  
CIARAN M. FAIRMAN ◽  
TORMOD S. NILSEN ◽  
ROBERT U. NEWTON ◽  
DENNIS R. TAAFFE ◽  
NIGEL SPRY ◽  
...  

Cancer ◽  
2019 ◽  
Vol 125 (19) ◽  
pp. 3437-3447 ◽  
Author(s):  
Daniel Santa Mina ◽  
Darren Au ◽  
Leslie E. Auger ◽  
Shabbir M. H. Alibhai ◽  
Andrew G. Matthew ◽  
...  
Keyword(s):  

2019 ◽  
Vol 18 ◽  
pp. 153473541983946 ◽  
Author(s):  
Karen Y. Wonders ◽  
Rob Wise ◽  
Danielle Ondreka ◽  
Josh Gratsch

Background: The physical and economic toll of cancer make it a high health priority. The rising cost of cancer care is now a primary focus for patients, payers, and providers. Escalating costs of clinical trials and national drug regulations have led the median monthly costs of cancer drugs to rise from less than $100 in 1965 to 1969, to more than $5000 in 2005 to 2009, stressing the importance of finding innovative ways to reduce cost burden. In the present study, we report the economic evaluation of an individualized exercise oncology program beginning early after diagnosis. Methods: An independent research group, ASCEND Innovations, retrospectively analyzed patient records to statistically demonstrate the impact of exercise oncology during cancer treatment. All patients completed 12 weeks of prescribed, individualized exercise that included cardiovascular, strength training, and flexibility components. The 3 primary hospital measures leveraged for statistical comparison before and after supportive care enrollment were number of encounters, number of readmissions, and average total charges, as well as emergency room visits and length of hospital stay ( P < .05). Results: The resulting dataset consisted of 1493 total hospital encounters for 147 unique patients. The results statistically demonstrate a positive effect of exercise oncology during cancer care, in terms of reductions in overall cost per patient pre- to post-intervention. Conclusions: Individualized exercise oncology programs should be employed as part of the national standard of care for individuals battling cancer, in order to improve patient outcome and reduce cost burden.


2017 ◽  
Vol 24 (3) ◽  
pp. 191 ◽  
Author(s):  
M.A. Dalzell ◽  
N. Smirnow ◽  
W. Sateren ◽  
A. Sintharaphone ◽  
M. Ibrahim ◽  
...  

Introduction The Rehabilitation and Exercise Oncology model of care (ActivOnco) was established to optimize cancer survivorship through exercise prescription and active lifestyle promotion, providing a transition of care from hospital to community. Patients having any cancer diagnosis, stage of disease, and treatment were eligible for evaluation and exercise prescription upon deterioration of performance status. The team of professionals included hospital-based physiotherapists proactively screening for rehabilitation needs, loss of functional independence, and exercise eligibility, plus exercise specialists in a community-based Wellness Centre to provide follow-up or direct access for post-treatment or non-complex patients.Methods From January 2011 to December 2015, the hospital team assessed 1635 patients representing all major cancer sites, and the Wellness Centre team evaluated and prescribed exercise for 1066 participants. Primary interventions provided were education about fatigue management, physical activity promotion, exercise prescription, fracture risk reduction, referral to specialized follow-up services (for example, occupational therapy, lymphedema clinic), and coordination for mobility aids and paratransit services.Results and Conclusions Implementation of the ActivOnco model of care showed that exercise alone is not a panacea for all functional deterioration associated with the cancer trajectory and its treatment. However, screening to identify rehabilitation needs combined with exercise prescription can effectively improve the quality of survivorship in cancer patients. Program developments are limited by the cost of human resources, lack of hospital-based physical resources, and lack of public funding, all of which significantly limit the scope and development of appropriate services.


2017 ◽  
Vol 27 (7) ◽  
pp. 1560-1567 ◽  
Author(s):  
Christelle Schofield ◽  
Robert U. Newton ◽  
Daniel A. Galvão ◽  
Paul A. Cohen ◽  
Carolyn J. Peddle-McIntyre

ObjectivePhysical activity has become increasingly important in supportive cancer care. However, physical activity and exercise guidelines for ovarian cancer survivors remain generic. The aim of this narrative review is to summarize existing data regarding the physiological characteristics (treatment-related adverse effects, concurrent comorbidities, body weight and composition, physical fitness and function, and physical activity behavior) of ovarian cancer survivors to further understanding of their cancer-specific physical activity and exercise needs. We also highlight gaps in the current knowledge base.MethodsWe undertook a narrative review of current literature on the physiological status of ovarian cancer survivors. We defined physiological status as treatment-related adverse effects, concurrent comorbidities, body weight and composition, physical fitness and function, and physical activity behavior.ResultsIn addition to disease- and treatment-related symptoms and adverse effects, the majority of ovarian cancer survivors have comorbidities, which may adversely affect treatment effectiveness and safety, as well as survival. Despite high overweight and obesity rates, a large percentage of women are malnourished at diagnosis, with potentially compromised muscle mass and muscle density. Low muscle density at diagnosis and loss of muscle mass during treatment may be associated with worse survival outcomes. A small number of studies have observed impaired physical function and cardiorespiratory fitness in ovarian cancer survivors. The majority of ovarian cancer survivors are insufficiently active or sedentary.ConclusionsOur review suggests that ovarian cancer survivors could benefit from physical activity and exercise oncology interventions aimed at addressing detrimental changes to physiological status due to disease and treatment. However, current knowledge gaps regarding the physiological characteristics of ovarian cancer survivors throughout the entire survivorship spectrum challenge the development of tailored exercise intervention studies and exercise oncology guidelines.


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