The Structure and Function of Living Organisms

2013 ◽  
pp. 1-32 ◽  
Author(s):  
Leszek Konieczny ◽  
Irena Roterman-Konieczna ◽  
Paweł Spólnik
2006 ◽  
Vol 2 (3) ◽  
pp. 439-442 ◽  
Author(s):  
Gregory P Dietl ◽  
Jonathan R Hendricks

Biological asymmetries are important elements of the structure and function of many living organisms. Using the Plio–Pleistocene fossil record of crab predation on morphologically similar pairs of right- and left-handed snail species, we show here for the first time, contrary to traditional wisdom, that rare left-handed coiling promotes survival from attacks by right-handed crabs. This frequency-dependent result influences the balance of selection processes that maintain left-handedness at the species level and parallels some social interactions in human cultures, such as sports that involve dual contests between opponents of opposite handedness.


2015 ◽  
Vol 59 ◽  
pp. 43-69 ◽  
Author(s):  
Helen Watson

Biological membranes allow life as we know it to exist. They form cells and enable separation between the inside and outside of an organism, controlling by means of their selective permeability which substances enter and leave. By allowing gradients of ions to be created across them, membranes also enable living organisms to generate energy. In addition, they control the flow of messages between cells by sending, receiving and processing information in the form of chemical and electrical signals. This essay summarizes the structure and function of membranes and the proteins within them, and describes their role in trafficking and transport, and their involvement in health and disease. Techniques for studying membranes are also discussed.


Author(s):  
James R. Gosz ◽  
Avi Perevolotsky

Biodiversity is regarded as a scientific concept, a measurable entity, as well as a social–political construct (Gaston 1996, Wilson 1993). The aim of this volume is to develop the scientific basis for biodiversity studies, and for the integration of the concept into management practice. We emphasize biodiversity as a powerful, integrative concept—one that requires careful articulation and further conceptualization before application. Diversity is a concept that refers to the range of variation or differences among a set of entities; biological diversity then refers to variety within the living world. An example of biological diversity is “species diversity,” which is commonly used to describe the number, variety, and variability of the assemblage of living organisms in a defined area or space. However, biodiversity as a concept has evolved. Current definitions expand the biological diversity concept to emphasize the multiple dimensions and ecological realms in which biodiversity can be observed. These definitions stress that biodiversity encompasses at least four kinds of diversities: genetic diversity, species or taxonomic diversity, ecosystem diversity, and landscape diversity (McAllister 1991; Solbrig 1993, Stuart and Adams 1991; Groombridge 1992; Heywood 1994, Wilson 1993). Two main problems emerge as a consequence of the broad scope that the biodiversity concept has taken at present. Cast as questions, the problems are: (1) How do we incorporate processes (e.g., foraging, energy and nutrient flows, patch dynamics) into a concept that is based on seemingly static entities (i.e., individual organisms, species, habitat types, patch types)? (2) How do we integrate across ecological subdisciplines (e.g., ecosystem, population, landscape ecology) and across scales that are involved in biodiversity studies? The two problems are not mutually exclusive. Indeed, they are inseparable and complementary. For example, to determine how species diversity and ecosystem processes interact requires incorporation of entities and processes, as well as integration of community and ecosystem ecology. The focus on both entities and processes reflects the long-recognized dichotomy of structure and function in biology and ecology. Clearly, both structure and function must be integrated in order to successfully solve ecological questions. Dealing with biodiversity brings this needed integration into focus.


Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3351 ◽  
Author(s):  
Jinkui Li ◽  
Lingya Zhang ◽  
Junwen Xiong ◽  
Xiyao Cheng ◽  
Yongqi Huang ◽  
...  

Polyamines are positively charged small molecules ubiquitously existing in all living organisms, and they are considered as one kind of the most ancient cellular components. The most common polyamines are spermidine, spermine, and their precursor putrescine generated from ornithine. Polyamines play critical roles in cells by stabilizing chromatin structure, regulating DNA replication, modulating gene expression, etc., and they also affect the structure and function of proteins. A few studies have investigated the impact of polyamines on protein structure and function previously, but no reports have focused on a protein-based biological module with a dedicated function. In this report, we investigated the impact of polyamines (putrescine, spermidine, and spermine) on the cyanobacterial KaiABC circadian oscillator. Using an established in vitro reconstitution system, we noticed that polyamines could disrupt the robustness of the KaiABC oscillator by inducing the denaturation of the Kai proteins (KaiA, KaiB, and KaiC). Further experiments showed that the denaturation was likely due to the induced change of the thermal stability of the clock proteins. Our study revealed an intriguing role of polyamines as a component in complex cellular environments and would be of great importance for elucidating the biological function of polyamines in future.


2015 ◽  
Vol 210 (1) ◽  
pp. 7-8 ◽  
Author(s):  
Wendy S. Garrett

Cell biology is the study of the structure and function of the unit or units of living organisms. Enabled by current and evolving technologies, cell biologists today are embracing new scientific challenges that span many disciplines. The eclectic nature of cell biology is core to its future and remains its enduring legacy.


2017 ◽  
Vol 8 (2) ◽  
pp. 105-118 ◽  
Author(s):  
Giovanna De Simone ◽  
Paolo Ascenzi ◽  
Alessandra di Masi ◽  
Fabio Polticelli

AbstractClassical all α-helical globins are present in all living organisms and are ordered in three lineages: (i) flavohemoglobins and single domain globins, (ii) protoglobins and globin coupled sensors and (iii) truncated hemoglobins, displaying the 3/3 or the 2/2 all α-helical fold. However, over the last two decades, all β-barrel and mixed α-helical-β-barrel heme-proteins displaying heme-based functional properties (e.g. ligand binding, transport and sensing) closely similar to those of all α-helical globins have been reported. Monomeric nitrophorins (NPs) and α1-microglobulin (α1-m), belonging to the lipocalin superfamily and nitrobindins (Nbs) represent prototypical heme-proteins displaying the all β-barrel and mixed α-helical-β-barrel folds. NPs are confined to the Reduviidae and Cimicidae families of Heteroptera, whereas α1-m and Nbs constitute heme-protein families spanning bacteria to Homo sapiens. The structural organization and the reactivity of the stable ferric solvent-exposed heme-Fe atom suggest that NPs and Nbs are devoted to NO transport, storage and sensing, whereas Hs-α1-m participates in heme metabolism. Here, the structural and functional properties of NPs and Nbs are reviewed in parallel with those of sperm whale myoglobin, which is generally taken as the prototype of monomeric globins.


2007 ◽  
Vol 29 (5) ◽  
pp. 12-15
Author(s):  
James L. Hartley

According to the online reference source Wikipedia (www.wikipedia.org), biochemistry is “the study of the chemical processes and transformations in living organisms. It deals with the structure and function of cellular components, such as proteins, carbohydrates, lipids, nucleic acids and other biomolecules.” It seems appropriate to start with a definition from the World Wide Web, which has changed information retrieval as much as DNA cloning has changed biochemistry. Here I attempt to provide some perspectives on that transformation.


Author(s):  
Peter Sterling

The synaptic connections in cat retina that link photoreceptors to ganglion cells have been analyzed quantitatively. Our approach has been to prepare serial, ultrathin sections and photograph en montage at low magnification (˜2000X) in the electron microscope. Six series, 100-300 sections long, have been prepared over the last decade. They derive from different cats but always from the same region of retina, about one degree from the center of the visual axis. The material has been analyzed by reconstructing adjacent neurons in each array and then identifying systematically the synaptic connections between arrays. Most reconstructions were done manually by tracing the outlines of processes in successive sections onto acetate sheets aligned on a cartoonist's jig. The tracings were then digitized, stacked by computer, and printed with the hidden lines removed. The results have provided rather than the usual one-dimensional account of pathways, a three-dimensional account of circuits. From this has emerged insight into the functional architecture.


Author(s):  
K.E. Krizan ◽  
J.E. Laffoon ◽  
M.J. Buckley

With increase use of tissue-integrated prostheses in recent years it is a goal to understand what is happening at the interface between haversion bone and bulk metal. This study uses electron microscopy (EM) techniques to establish parameters for osseointegration (structure and function between bone and nonload-carrying implants) in an animal model. In the past the interface has been evaluated extensively with light microscopy methods. Today researchers are using the EM for ultrastructural studies of the bone tissue and implant responses to an in vivo environment. Under general anesthesia nine adult mongrel dogs received three Brånemark (Nobelpharma) 3.75 × 7 mm titanium implants surgical placed in their left zygomatic arch. After a one year healing period the animals were injected with a routine bone marker (oxytetracycline), euthanized and perfused via aortic cannulation with 3% glutaraldehyde in 0.1M cacodylate buffer pH 7.2. Implants were retrieved en bloc, harvest radiographs made (Fig. 1), and routinely embedded in plastic. Tissue and implants were cut into 300 micron thick wafers, longitudinally to the implant with an Isomet saw and diamond wafering blade [Beuhler] until the center of the implant was reached.


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