Regulation of Cutaneous Stress Response Pathways by the Circadian Clock: From Molecular Pathways to Therapeutic Opportunities

2016 ◽  
pp. 281-300 ◽  
Author(s):  
Elyse van Spyk ◽  
Milton Greenberg ◽  
Faraj Mourad ◽  
Bogi Andersen
Keyword(s):  
Stress Response ◽  
Circadian Clock ◽  
Molecular Pathways

Insights into molecular pathways and fatty acid membrane composition during the temperature stress response in the murine C2C12 cell model

2021 ◽  
pp. 151019
Author(s):  
Marua Abu Risha ◽  
Asghar Ali ◽  
Puntita Siengdee ◽  
Nares Trakooljul ◽  
Dirk Dannenberger ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Stress Response ◽  
Temperature Stress ◽  
Cell Model ◽  
C2c12 Cell ◽  
Molecular Pathways ◽  
Membrane Composition

scholarly journals Denervation does not induce muscle atrophy through oxidative stress

2017 ◽  
Vol 27 (1) ◽  
Author(s):  
Eva Pigna ◽  
Emanuela Greco ◽  
Giulio Morozzi ◽  
Silvia Grottelli ◽  
Alessio Rotini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Stress Response ◽  
Muscle Atrophy ◽  
Oxidative Stress Response ◽  
Skeletal Muscle Atrophy ◽  
Molecular Pathways ◽  
Ubiquitin Proteasome ◽  
Anti Oxidant ◽  
Kinetics Of

Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness. Furthermore, denervation induces oxidative stress in skeletal muscle, which is thought to contribute to the induction of skeletal muscle atrophy. Several muscle diseases are characterized by denervation, but the molecular pathways contributing to muscle atrophy have been only partially described. Our study delineates the kinetics of activation of oxidative stress response in skeletal muscle following denervation. Despite the denervation-dependent induction of oxidative stress in skeletal muscle, treatments with anti-oxidant drugs do not prevent the reduction of muscle mass. Our results indicate that, although oxidative stress may contribute to the activation of the response to denervation, it is not responsible by itself of oxidative damage or neurogenic muscle atrophy.

Plant circadian networks and responses to the environment

2018 ◽  
Vol 45 (4) ◽  
pp. 393 ◽  
Author(s):  
Chenjerai I. Muchapirei ◽  
Shannon-Leigh Valentine ◽  
Laura C. Roden
Keyword(s):  
Stress Response ◽  
Circadian Clock ◽  
Environmental Changes ◽  
Hierarchical Control ◽  
Metabolic Efficiency ◽  
The Sun ◽  
Biological Processes ◽  
Post Translational Modifications ◽  
Biological Time ◽  
Reciprocal Interactions

There are regular, and therefore predictable, environmental changes on Earth due to the rotation of the planet on its axis and its orbit around the sun. Thus organisms have adapted their metabolism, physiology and behaviour to minimise stresses caused by unfavourable conditions and maximise efficiency of growth. Additionally, most organisms are able to anticipate these changes and accordingly maximise metabolic efficiency and growth, because they have a complex biological time-keeping system commonly referred to as the circadian clock. Multiple pathways in plants are organised in a temporal manner through circadian clock-regulation of gene transcription and post-translational modifications. What is becoming more apparent is the bidirectional nature of interactions between the clock and stress response pathways. Until recently, the focus of many studies had been on the unidirectional, hierarchical control of biological processes by the circadian clock, and impacts on the clock in response to environmental stress had been largely ignored. Studies of interactions of the circadian clock with the environment have primarily been to understand mechanisms of entrainment. We review the evidence and implications of the reciprocal interactions between the clock and the environment.

scholarly journals Transcript Profiling of an Arabidopsis PSEUDO RESPONSE REGULATOR Arrhythmic Triple Mutant Reveals a Role for the Circadian Clock in Cold Stress Response

2009 ◽  
Vol 50 (3) ◽  
pp. 447-462 ◽  
Author(s):  
Norihito Nakamichi ◽  
Miyako Kusano ◽  
Atsushi Fukushima ◽  
Masanori Kita ◽  
Shogo Ito ◽  
...  
Keyword(s):  
Stress Response ◽  
Cold Stress ◽  
Circadian Clock ◽  
Response Regulator ◽  
Transcript Profiling ◽  
Triple Mutant ◽  
Pseudo Response Regulator

Differential gene expression reveals candidate genes for osmotic stress response in faba bean (Vicia faba L.) involved in different molecular pathways

2021 ◽  
Vol 43 (3) ◽  
Author(s):  
Ghassen Abid ◽  
Mohammed Najib Saidi ◽  
Rim Nefissi Ouertani ◽  
Yordan Muhovski ◽  
Salwa Harzalli Jebara ◽  
...  
Keyword(s):  
Gene Expression ◽  
Stress Response ◽  
Osmotic Stress ◽  
Candidate Genes ◽  
Vicia Faba ◽  
Faba Bean ◽  
Molecular Pathways ◽  
Osmotic Stress Response ◽  
Vicia Faba L ◽  
Differential Gene

Circadian Clock Boosts Stress-Response Genes During Aging

JAMA ◽  
2017 ◽  
Vol 317 (13) ◽  
pp. 1307
Author(s):  
Tracy Hampton
Keyword(s):  
Stress Response ◽  
Circadian Clock ◽  
Stress Response Genes
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