Analysis of Changes in Agronomic Parameters and Disease Index of Rapeseed Leaf Leukoplakia Based on Spectra

2016 ◽  
pp. 637-653
Author(s):  
Kunya Fu ◽  
Hongxin Cao ◽  
Wenyu Zhang ◽  
Weixin Zhang ◽  
Daokuo Ge ◽  
...  
Keyword(s):  
Disease Index

scholarly journals Use of Plasma Rich in Growth Factors and ReGeneraTing Agent Matrix for the Treatment of Corneal Diseases

Vision ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 34
Author(s):  
Ronald M. Sánchez-Ávila ◽  
Edmar Uribe-Badillo ◽  
Carlos Fernández-Vega González ◽  
Francisco Muruzabal ◽  
Borja de la Sen-Corcuera ◽  
...  
Keyword(s):  
Growth Factors ◽  
Corneal Ulcer ◽  
Disease Index ◽  
Eye Drops ◽  
Analog Scale ◽  
Ocular Surface Disease Index ◽  
Corneal Ulcers ◽  
Corrected Visual Acuity ◽  
The Mean

This study aimed to investigate the use of Plasma Rich in Growth Factors (PRGF) associated with tissue ReGeneraTing Agent (RGTA) drops for the treatment of noninfectious corneal ulcers. RGTA treatment was applied (one drop every two days); however, if ulcer closure was not achieved, PRGF eye drops treatment was added (four times/day). The time taken to reach the ulcer closure, the Best Corrected Visual Acuity (BCVA), intraocular pressure (IOP), Visual Analog Scale (VAS, in terms of frequency and severity of symptoms), and Ocular Surface Disease Index (OSDI) were evaluated. Seventy-four patients (79 eyes) were included, and the mean age was 56.8 ± 17.3 years. The neurotrophic corneal ulcer was the most frequent disorder (n = 27, 34.2%), mainly for herpes virus (n = 15, 19.0%). The time of PRGF eye drops treatment associated with the RGTA matrix was 4.2 ± 2.2 (1.5–9.0) months, and the follow-up period was 44.9 ± 31.5 months. The ulcer closure was achieved in 76 eyes (96.2%). BCVA, VAS and OSDI improved from the baseline (p < 0.001), and IOP remained unchanged (p = 0.665). RGTA and PRGF in noninfectious ulcers were effective and could be a therapeutic alternative for this type of corneal disease.

scholarly journals Reliability and validity of the Japanese version of the Ocular Surface Disease Index for dry eye disease

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e033940 ◽  
Author(s):  
Akie Midorikawa-Inomata ◽  
Takenori Inomata ◽  
Shuko Nojiri ◽  
Masahiro Nakamura ◽  
Masao Iwagami ◽  
...  
Keyword(s):  
Internal Consistency ◽  
Dry Eye ◽  
Ocular Surface ◽  
Discriminant Validity ◽  
Reliability And Validity ◽  
Japanese Version ◽  
Disease Index ◽  
Eye Disease ◽  
Ocular Surface Disease Index ◽  
Test Retest Reliability

ObjectivesThe Ocular Surface Disease Index (OSDI) questionnaire is widely used to evaluate subjective symptoms of dry eye disease (DED) as a primary diagnostic criterion. This study aimed to develop a Japanese version of the OSDI (J-OSDI) and assess its reliability and validity.Design and settingHospital-based cross-sectional observational study.ParticipantsA total of 209 patients recruited from the Department of Ophthalmology at Juntendo University Hospital.MethodsWe translated and culturally adapted the OSDI into Japanese. The J-OSDI was then assessed for internal consistency, reliability and validity. We also evaluated the optimal cut-off value to suspect DED using an area under the receiver operating characteristic curve (AUC) analysis.Primary outcome measuresInternal consistency, test–retest reliability and discriminant validity of the J-OSDI as well as the optimal cut-off value to suspect DED.ResultsOf the participants, 152 had DED and 57 did not. The J-OSDI total score showed good internal consistency (Cronbach's alpha=0.884), test–retest reliability (interclass correlation coefficient=0.910) and discriminant validity by known-group comparisons (non-DED, 19.4±16.0; DED, 37.7±22.2; p<0.001). Factor validity was used to confirm three subscales within the J-OSDI according to the original version of the questionnaire. Concurrent validity was assessed by Pearson correlation analysis, and the J-OSDI total score showed a strong positive correlation with the Dry Eye-Related Quality-of-Life Score (γ=0.829). The optimal cut-off value of the J-OSDI total score was 36.3 (AUC=0.744).ConclusionsThe J-OSDI was developed and validated in terms of reliability and validity as an effective tool for DED assessment and monitoring in the Japanese population.

Fetal ascites and oligohydramnios: Prenatal diagnosis of a sialic acid storage disease (index case)

1995 ◽  
Vol 15 (9) ◽  
pp. 864-867 ◽  
Author(s):  
P. Poulain ◽  
S. Odent ◽  
I. Maire ◽  
J. Milon ◽  
J. F. Proudhon ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Sialic Acid ◽  
Storage Disease ◽  
Index Case ◽  
Disease Index ◽  
Sialic Acid Storage Disease

scholarly journals AB0830 LIPID PROFILE IN PSORIATIC ARTHRITIS. FREQUENCY AND ASSOCIATION WITH DISEASE ACTIVITY.

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1719.1-1720
Author(s):  
V. Savio ◽  
Y. Tissera ◽  
M. I. Quaglia ◽  
J. A. Albiero ◽  
C. G. Alonso ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Psoriatic Arthritis ◽  
Disease Activity ◽  
Lipid Profile ◽  
Activity Index ◽  
Laboratory Data ◽  
Disease Index ◽  
Interleukin 12 ◽  
Joint Involvement ◽  
Apo B

Background:Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with higher risk of cardiovascular events and metabolic syndrome. The inflammation not only accelerates atherosclerosis, but also may influence cardiovascular (CV) risk factors such as lipid profile, blood pressure and insulin resistance. Lipid profile has previously been studied in PsA, however this association is still controversial.Objectives:To study the frequency of altered lipid profile in patients with PsA and its association with disease activity.Methods:We studied all the patients with diagnosis of PsA who consecutively attended to Rheumatology Unit at Cordoba Hospital from July 2018 to December 2019. PsA was diagnosed according CASPAR criteria. Clinical and laboratory data were collected. The activity of the disease was evaluated by PASI, MDA and DAPSA. Quantitative variables will be expressed in median and 1st and 3rd interquartile; qualitative variables expressed in frequency and percentage. Correlation analysis was calculated using Spearman’s rank correlation coefficient. P<0.05 was considered statistically significant.Results:42 PsA patients were included. Mean age was 56 years old (47.25-62.75) and 54.76% were female (n=23). 92.86% (n=39) of the patients had plaque Psoriasis and 87.8% (n=36) had peripheral joint involvement.Frequency of comorbidities in PsA are shown in Graphic 1. 31 (73.8%) of the patients were treated with topical therapy, 3 (7.14%) with phototherapy, 31 (73.8%) with Methotrexate and 17 (41.46%) with biologics and JAK inhibitor. Activity Disease Index and Lipid profile are shown in Table 1 and 2.There was not association between Apo B/Apo A coefficient with DAPSA (rho=0.013; p=0.940) and MDA (rho=-0.029; p=0.867).Conclusion:In spite of the presence of cardiovascular factors in the majority of PsA patients, lipid profile is not correlated with disease activity in this population.References:[1]Ahlehoff O, Gislason GH, Charlot M, et al. Psoriasis is associated with clinically significant cardiovascular risk: A Danish nationwide cohort study. J Intern Med 2011;270:147-57.[2]Mallbris, L., Ritchlin, C.T., Ståhle, M. “Metabolic disorders in patients with psoriasis and psoriatic arthritis.” Curr RheumatolRep.8(5): 355–363. 2006[3]Ng CY, Tzeng I-S, Liu S-H, Chang Y-C, Huang Y-H. Metabolic parameters in psoriatic patients treated with interleukin-12/23 blockade (Ustekinumab). J Dermatol 2018; 45:309–313[4]Kaur S, Kingo K, Zilmer M. Psoriasis and cardiovascular risk – do promising new biomarkers have clinical impact? Mediators Inflamm 2017; 2017: 7279818[5]Gentile M, Peluso R, Di Minno MN, et al. Association between small dense LDL and sub-clinical atherosclerosis in patients with psoriatic arthritis. ClinRheumatol 2016; 35: 2023-9.Graphic 1.Comorbidities in PsATable. 1.Activity Disease Index in PsAACTIVITY INDEXn=42DAPSA14.45 (9.72-23.92)DAPSA≤4 REMISSION3>4 y ≤14 low disease activity16>14 y ≤28 moderate disease activity17>28 high disease activity3cDAPSA14.00 (8.00-23.00)/41*MDA9 (25)/36PASI2.20 (0.20-6.80)/41**Expressed in median and interquartiles.Qualitative variables expressed in frequency and percentage.Table. 2.Lipid Profile in PsA patients.Cholesterol (mg/dl)194.5 (164.8-218.2)HDL (mg/dl)48.00 (37.00-57.00)LDL (mg/dl)114.5 (78.5-140.8)TG (mg/dl)139.50 (89.25-191.20)Expressed in median and interquartiles.Disclosure of Interests:None declared

Allelopathic effects of ginsenoside on soil sickness, soil enzymes, soil disease index and plant growth of Ginseng

2021 ◽  
Vol 52 (2) ◽  
pp. 251-260
Author(s):  
Yu Zhan ◽  
Enpeng Wang ◽  
Huan Wang ◽  
Xue Chen ◽  
Xiangru Meng ◽  
...  
Keyword(s):  
Acid Phosphatase ◽  
Soil Enzymes ◽  
Disease Index ◽  
Ginseng Root ◽  
Limiting Factor ◽  
High Concentration ◽  
Soil Sickness ◽  
Soil Urease ◽  
Allelopathic Effects ◽  
Ginseng Cultivation

Soil sickness of ginseng (Panax ginseng C. A. Mey.) has become a major limiting factor in ginseng cultivation. We found that Total Ginsenoside in Ginseng Root (TSPG) significantly decreased the activities of soil urease, acid phosphatase and laccase. Its high concentration of TSPG (10.00 mg L-1) significantly reduced the activity of soil sucrose. Besides, the TSPG can inhibited the growth of ginseng and increased the incidence of disease. Therefore, allelopathic effects of TSPG may be one of the main causes of Soil Sickness in ginseng.

scholarly journals Susceptibility of winter Triticale Cultivars to Rhizoctonia Cerealis (sharp eyespot) and R. Solani

2012 ◽  
Vol 52 (4) ◽  
pp. 421-434 ◽  
Author(s):  
Grzegorz Lemańczyk
Keyword(s):  
Field Study ◽  
Growth Stage ◽  
Disease Index ◽  
High Susceptibility ◽  
North Central ◽  
Winter Triticale ◽  
Sharp Eyespot ◽  
The Mean ◽  
Rhizoctonia Cerealis ◽  
Seedling Infection

AbstractIn the field study period from 2006 to 2010, the incidence and severity of sharp eyespot caused byRhizoctoniawere recorded on 36 cultivars of triticale at the milk ripe growth stage. Four localities in north-central Poland were included: Chrząstowo, Dębina, Kończewice and Minikowo. The susceptibility of the seedlings of 30 cultivars of triticale toR. cerealis(AG-D subgroup I) andR. solani(AG-5) was studied in the laboratory. There was much variation in incidence and severity of sharp eyespot between years and locations. The disease was most intense at Chrząstowo. At this location, the mean percentage of diseased stems on 28 cultivars was 2.6-35.7 (-55.0), and the mean disease index was 0.7-15.6 (-24.5), with the lowest and highest values in 2008 and 2009, respectively. At Minikowo, the disease was least intense. At this location, the mean percentage of diseased stems on 23 cultivars was 1.0-4.6 (-18.0), and the mean disease index was 0.3-1.4 (-6.3), with the lowest and highest values in 2006 and 2007, respectively. The cultivars with least intense disease were Tulus and Atletico (Chrząstowo), Grenado and Zorro (Dębina), Krakowiak and Tornado (Kończewice), and Woltario and Constans (Minikowo). The cultivars with most intense disease were Alekto (Chrząstowo), Baltiko (Dębina), Pawo (Kończewice) and Borwo (Minikowo). MostlyR. cerealiswas isolated from the diseased stems;R. solaniwas isolated only sporadically. There was a wide variation in the susceptibility of triticale cultivars toRhizoctonia. Most triticale seedlings inoculated withR. cerealisproduced symptoms typical of sharp eyespot. Seedlings inoculated withR. solaniformed extended lesions with no defined borders. Most symptoms developed on coleoptiles, with less symptoms on the leaves and the least on the roots. There was much variation in susceptibility of triticale cultivars to bothRhizoctoniaspecies. Cultivars were grouped into six categories according to the intensity of seedling infection. Categories 1, 2 and 3, representing low, moderate and high susceptibility toR. cerealis, included 17, 10 and 3 cultivars, respectively.Categories 4, 5 and 6, representing low, moderate and high susceptibility toR. solani, included 3, 12 and 15 cultivars, respectively.Cultivars Baltiko and Zorro had low, and cv. Cultivo had high susceptibility to bothRhizoctoniaspecies. No cultivar was resistant toRhizoctonia. There was a positive correlation between infection byR. cerealisandR. solani.Infection of coleoptiles byR. cerealisorR. solaniwas significantly correlated with infection of leaves. No correlation between intensity of sharp eyespot on triticale plants in the field and on seedlings in controlled conditions was found.

scholarly journals Pathotypes of Xanthomonas axonopodis pv. dieffenbachiae Isolated from Anthurium andraeanum in China

Pathogens ◽  
2018 ◽  
Vol 7 (4) ◽  
pp. 85
Author(s):  
Shuang-Chun Li ◽  
Wei-Da Zeng ◽  
Xing-Wei Li ◽  
Xiao-Yun Zhou ◽  
Qiong-Guang Liu
Keyword(s):  
Population Structure ◽  
Disease Susceptibility ◽  
Foliar Spray ◽  
Disease Index ◽  
Xanthomonas Axonopodis ◽  
Resistant Varieties ◽  
Medium Level ◽  
Anthurium Andraeanum ◽  
Highly Virulent ◽  
Susceptibility Patterns

Anthurium blight, caused by Xanthomonas axonopodis pv. dieffenbachiae (Xad), is one of the most serious diseases of Anthurium andraeanum. However, little is known about variations in virulence between Xad pathotypes. Here, we examined the virulence of 68 Xad strains isolated from 30 anthurium plants from five regions of China against five different anthurium cultivars. Seven bacterial pathotypes were identified based on disease index and incidence analyses following foliar spray or leaf-clip inoculation. The resulting disease susceptibility patterns for pathotypes I–VII were RRRSS, RRSRS, RSRSR, RRSSS, RSSRS, RSSSS, and SSSSS, respectively. Overall, 72% of tested strains belonged to pathotypes VI or VII and were highly virulent. A further 22.1% of strains showed medium-level virulence and were classed as pathotype III, IV, or V, while the remaining 5.9% of strains were pathotype I or II, showing low virulence. Further analysis revealed differences in the virulence of Xad strains from the same anthurium cultivar, with variation also observed in pathovars associated with the same cultivar from different areas. Our results reveal the diversity and complexity of the Xad population structure in China and suggest that investigation of Xad pathotypes provides useful information to guide the identification and use of resistant varieties of A. andraeanum.

scholarly journals Cotton resistance to ramulose and variability of Colletotrichum gossypii f. sp. cephalosporioides

2006 ◽  
Vol 32 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Jefferson Fernandes do Nascimento ◽  
Laércio Zambolim ◽  
Francisco Xavier Ribeiro do Vale ◽  
Paulo Geraldo Berger ◽  
Paulo Roberto Cecon
Keyword(s):  
Disease Severity ◽  
Disease Incidence ◽  
Disease Index ◽  
Mato Grosso ◽  
Progress Curve ◽  
Commercial Cultivars ◽  
Resistant Group ◽  
The Relationship ◽  
Highly Virulent ◽  
Susceptible Group

Four cultivars and 21 lines of cotton were evaluated for resistance to ramulose (Colletotrichum gossypii f. sp. cephalosporioides) in a field where the disease is endemic. The seeds of each genotype were planted in 5 x 5 m plots with three replications. The lines CNPA 94-101 and 'CNPA Precoce 2'were used as standard susceptible and resistant references, respectively. The disease incidence (DI) was calculated from the proportion of diseased plants in the plot. The disease index (DIn) was calculated from the disease severity using a 1 to 9 scale, and was evaluated at weekly intervals starting 107 days after emergence. The data collected was used to calculate the area under disease progress curve (AUDPC). In general, the DIn increased linearly with time and varied from 20.0 to 57.1 and AUDPC from 567 to 1627 among the genotypes which could be clustered in to two distinct groups. The susceptible group contained two cultivars and nine lines and the resistant group contained one cultivar and 12 lines. The relationship between disease index and evaluation times was linear for the 25 genotypes tested. The line CNPA 94-101, used as susceptible standard, was the most susceptible with an average DI = 83.4, DIn = 57.1 and AUDPC = 1627.7. The line CNPA 96-08 with DI = 37.8, DIn = 20.0 and AUDPC = 567.7 was the most resistant one. Among the commercial cultivars 'IAC 22' was the most susceptible and 'CNPA Precoce 2', used as resistant standard was the most resistant. The variability in virulence of the pathogen was studied by spray inoculating nine genotypes with conidial suspensions (10(5)/mL) of either of the 10 isolates. The disease severity was evaluated 30 days later using a scale of 1 to 5. The virulence of the isolate was expressed by DIn. All the isolates were highly virulent but their virulence avaried for several genotypes and could be clustered in two distinct groups of less and more virulent isolates. The isolate MTRM 14 from Mato Grosso was the least virulent while Minas Gerais was the most virulent, with DIn of 6.36 and 46.47, respectively. In this experiment the line HR 102 and the cultivar 'Antares' were the most resistant ones with DIns of 18.32 and 19.14, respectively.

scholarly journals Identification of new resistant sources against downy mildew disease from a selected set of cucumber germplasm and its wild relatives

2020 ◽  
Vol 80 (04) ◽  
Author(s):  
Jameel Akhtar ◽  
Dikshant Gautam ◽  
Ranjan Nath ◽  
A. B. Gaikwad ◽  
K. V. Bhat ◽  
...  
Keyword(s):  
Downy Mildew ◽  
Plant Disease ◽  
Mapping Population ◽  
Disease Index ◽  
Sources Of Resistance ◽  
Resistant Accession ◽  
Genomic Regions ◽  
Moderately Resistant ◽  
Agroclimatic Zones ◽  
Downy Mildew Disease

This study was undertaken to identify new sources of resistance against downy mildew of cucumber caused by Pseudoperonospora cubensis [(Berk. and Cart.) Rostow]. Pot experiments were conducted with 16 accessions each of Cucumis sativus and C. hardwickii during the years 2017 and 2018 using 12 isolates of P. cubensis representing different agroclimatic zones of India. The accession, IC331627 from Dehradun, Uttarakhand showed plant disease index (PDI) ranging from 5.55-20.35 per cent with an average PDI of 11.56 and 11.87 per cent during the years, 2017 and 2018, respectively. Hence, IC331627 was identified to be resistant against the five isolates of P. cubesis (Pc12, Pc17, Pc19, Pc21 and Pc24) and moderately resistant against one isolate (Pc22). This resistant accession C. hardwickii (IC331627) could be utilized to develop mapping population to map genomic regions conferring the resistance to downy mildew in cucumber.

scholarly journals Changes in Tear-Film Status and Ocular Surface Disease Index Score Following Prolonged Use of Face Mask

2021 ◽  
Vol 11 (04) ◽  
pp. 253-265
Author(s):  
Nawreen Binte Anwar ◽  
Basil Anwar ◽  
Arup Krishna Choudhury ◽  
Mahfuza Rahman Khan ◽  
Md. Anisur Rahman
Keyword(s):  
Ocular Surface ◽  
Tear Film ◽  
Face Mask ◽  
Disease Index ◽  
Index Score ◽  
Ocular Surface Disease ◽  
Ocular Surface Disease Index ◽  
Score Following
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