scholarly journals Efficiently Finding the Best Parameter for the Emerging Pattern-Based Classifier PCL

2010 ◽  
pp. 121-133 ◽  
Author(s):  
Thanh-Son Ngo ◽  
Mengling Feng ◽  
Guimei Liu ◽  
Limsoon Wong
Keyword(s):  
Best Parameter ◽  
Emerging Pattern

Inactivation of Factor XIa in Vivo: Studies in Chimpanzees and in Humans

1996 ◽  
Vol 76 (04) ◽  
pp. 549-555 ◽  
Author(s):  
Walter A Wuillemin ◽  
C Erik Hack ◽  
Wim K Bleeker ◽  
Bart J Biemond ◽  
Marcel Levi ◽  
...  
Keyword(s):  
Antithrombin Iii ◽  
Life Time ◽  
In Vivo Studies ◽  
Clinical Samples ◽  
Plasma Samples ◽  
C1 Inhibitor ◽  
Elimination Kinetics ◽  
Factor Xia ◽  
Best Parameter

SummaryC1-inhibitor (C1Inh), antithrombin III (ATIII), α1-antitrypsin (a1AT), and α2-antiplasmin (a2AP) are known inhibitors of factor XIa (FXIa). However, their precise contribution to FXIa inactivation in vivo is not known. We investigated FXIa inactivation in chimpanzees and assessed the contribution of these inhibitors to FXIa inactivation in patients with presumed FXI activation.Chimpanzees were infused with FXIa and the various FXIa-FXIa inhibitor complexes formed were measured. Most of FXIa was complexed to C1Inh (68%), followed by a2AP (13%), a1AT (10%), and ATIII (9%). Analysis of the plasma elimination kinetics revealed a half-life time of clearance (t1/2) for the FXIa-FXIa inhibitor complexes of 95 to 104 min, except for FXIa-a1AT, which had a t1/2 of 349 min. Due to this long t1/2, FXIa-a1AT complexes were predicted to show the highest levels in plasma samples from patients with activation of FXI. This was indeed shown in patients with disseminated intravascular coagulation, recent myocardial infarction or unstable angina pectoris. We conclude from this study that in vivo C1Inh is the predominant inhibitor of FXIa, but that FXIa-a1 AT complexes due to their relatively long t1/2 may be the best parameter to assess FXI activation in clinical samples.

Feasibility of utilizing sweet potato solids in extrusion cooking / Extrusión de pulpa de batata

1997 ◽  
Vol 3 (3) ◽  
pp. 171-174 ◽  
Author(s):  
H.M. Khalil ◽  
B.R. Henry
Keyword(s):  
Moisture Content ◽  
Sweet Potato ◽  
Sugar Content ◽  
Expansion Ratio ◽  
Fractional Factorial ◽  
Snack Food ◽  
Screw Speed ◽  
High Sugar Content ◽  
Feed Moisture ◽  
Best Parameter

A fractional factorial design of four variables at two levels each was employed to assess the feasi bility and best parameter for extruding sweet potato solids (SPS) using a single screw extruder. It was determined that a high expansion ratio is a desired quality factor for this type of snack food, due to its contribution to textural perception. Preliminary trials on extrusion of sweet potato solids as the sole component in the feed resulted in brittle, dense, and burnt extrudate. The high sugar content (65% total sugar) of the sweet potato solids was cited as the cause of these attrib utes, consequently it was necessary to incorporate wheat flour into the feed to provide a starch matrix for expansion and to reduce sugar concentration. The controlled parameters were screw speed, barrel temperature, feed moisture content, and SPS level in the feed. Among all possible combinations of controlled parameters, the highest expansion ratio was obtained at a screw speed of 220 rpm, temperature profile of 110, 105, 115 and 105 °C, 13% feed moisture content, 50% sweet potato solids, and 0.5% leavening agent.

scholarly journals Prolonged Cerebral Circulation Time Is the Best Parameter for Predicting Vasospasm during Initial CT Perfusion in Subarachnoid Hemorrhagic Patients

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0151772 ◽  
Author(s):  
Chun Fu Lin ◽  
Sanford P. C. Hsu ◽  
Chung Jung Lin ◽  
Wan Yuo Guo ◽  
Chih Hsiang Liao ◽  
...  
Keyword(s):  
Cerebral Circulation ◽  
Ct Perfusion ◽  
Circulation Time ◽  
Best Parameter ◽  
Cerebral Circulation Time

scholarly journals Measures of Bioavailable Serum Testosterone and Estradiol and Their Relationships with Muscle Strength, Bone Density, and Body Composition in Elderly Men*

2000 ◽  
Vol 85 (9) ◽  
pp. 3276-3282 ◽  
Author(s):  
Annewieke W. van den Beld ◽  
Frank H. de Jong ◽  
Diederick E. Grobbee ◽  
Huibert A. P. Pols ◽  
Steven W. J. Lamberts
Keyword(s):  
Body Composition ◽  
Muscle Strength ◽  
Fat Mass ◽  
Cross Sectional Study ◽  
Positive Relation ◽  
Elderly Men ◽  
Cross Sectional ◽  
Healthy Elderly ◽  
Hip Bmd ◽  
Best Parameter

Abstract In the present cross-sectional study of 403 independently living elderly men, we tested the hypothesis that the decreases in bone mass, body composition, and muscle strength with age are related to the fall in circulating endogenous testosterone (T) and estrogen concentrations. We compared various measures of the level of bioactive androgen and estrogen to which tissues are exposed. After exclusion of subjects with severe mobility problems and signs of dementia, 403 healthy men (age, 73–94 yr) were randomly selected from a population-based sample. Total T (TT), free T (FT), estrone (E1), estradiol (E2), and sex hormone-binding globulin (SHBG) were determined by RIA. Levels of non-SHBG-bound T (non-SHBG-T), FT (calc-FT), the TT/SHBG ratio, non-SHBG-bound E2, and free E2 were calculated. Physical characteristics of aging included muscle strength measured using dynamometry, total body bone mineral density (BMD), hip BMD, and body composition, including lean mass and fat mass, measured by dual-energy x-ray absorptiometry. In this population of healthy elderly men, calc-FT, non-SHBG-T, E1, and E2 (total, free, and non-SHBG bound) decreased significantly with age. T (total and non-SHBG-T) was positively related with muscle strength and total body BMD (for non-SHBG-T, respectively, β = 1.93 ± 0.52, P < 0.001 and β = 0.011 ± 0.002, P < 0.001). An inverse association existed between T and fat mass (β = −0.53 ± 0.15, P < 0.001). Non-SHBG-T and calc-FT were more strongly related to muscle strength, BMD, and fat mass than TT and were also significantly related to hip BMD. E1 and E2 were both positively, independently associated with BMD (for E2, β = 0.21 ± 0.08, P < 0.01). Non-SHBG-bound E2 was slightly strongly related to BMD than total E2. The positive relation between T and BMD was independent of E2. E1 and E2 were not related with muscle strength or body composition. In summary, bioavailable T, E1, total E2, and bioavailable E2 all decrease with age in healthy old men. In this cross-sectional study in healthy elderly men, non-SHBG-bound T seems to be the best parameter for serum levels of bioactive T, which seems to play a direct role in the various physiological changes that occur during aging. A positive relation with muscle strength and BMD and a negative relation with fat mass was found. In addition, both serum E1 and E2 seem to play a role in the age-related bone loss in elderly men, although the cross-sectional nature of the study precludes a definitive conclusion. Non-SHBG-bound E2 seems to be the best parameter of serum bioactive E2 in describing its positive relation with BMD.

scholarly journals Vulnerability of Latin American Migrant Families Headed by Women in Spain During the Great Recession: A Couple-Level Analysis

2018 ◽  
Vol 40 (1) ◽  
pp. 111-138
Author(s):  
Xiana Bueno ◽  
Elena Vidal-Coso
Keyword(s):  
Labor Market ◽  
Latin American ◽  
Great Recession ◽  
Family Characteristics ◽  
The Great Recession ◽  
Job Segregation ◽  
Dual Earner ◽  
Migrant Families ◽  
Level Analysis ◽  
Emerging Pattern

One of the outcomes of the Great Recession has been the emerging pattern of households maintained exclusively by women. The analysis of intracouple characteristics is crucial in the context of job segregation by gender and by immigrant origin, such as in Spain. Using the panel version of the Spanish Labor Force Survey from 2008 to 2015, we analyze the transition of dual-earner couples to female-earner couples among Latin American and Spanish-born households. Our results suggest that migrant vulnerability is not only a consequence of a segregated labor market by gender and origin but is also the result of the partners’ relative occupational and family characteristics. We show that, unlike Spanish-born couples, the risk of Latin American families becoming female-headed is higher for those couples in which the female partner has the weakest position in the occupational scale and for those with children in the household.

scholarly journals Fatigue Performance of ABS Specimens Obtained by Fused Filament Fabrication

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2521 ◽  
Author(s):  
Miquel Domingo-Espin ◽  
J. Antonio Travieso-Rodriguez ◽  
Ramon Jerez-Mesa ◽  
Jordi Lluma-Fuentes
Keyword(s):  
Acrylonitrile Butadiene Styrene ◽  
Experimental Phase ◽  
Fused Filament Fabrication ◽  
Layer Height ◽  
Bending Stresses ◽  
Best Parameter ◽  
End Use ◽  
Design And Manufacture ◽  
Printing Speed ◽  
Butadiene Styrene

In this paper, the fatigue response of fused filament fabrication (FFF) Acrylonitrile butadiene styrene (ABS) parts is studied. Different building parameters (layer height, nozzle diameter, infill density, and printing speed) were chosen to study their influence on the lifespan of cylindrical specimens according to a design of experiments (DOE) using the Taguchi methodology. The same DOE was applied on two different specimen sets using two different infill patterns—rectilinear and honeycomb. The results show that the infill density is the most important parameter for both of the studied patterns. The specimens manufactured with the honeycomb pattern show longer lifespans. The best parameter set associated to that infill was chosen for a second experimental phase, in which the specimens were tested under different maximum bending stresses so as to construct the Wöhler curve associated with this 3D printing configuration. The results of this study are useful to design and manufacture ABS end-use parts that are expected to work under oscillating periodic loads.

Sign in / Sign up

Export Citation Format

Share Document