Functional Outcomes in Rectal Cancer Patients After Surgical Treatment

2018 ◽  
pp. 221-228
Author(s):  
Sung-Bum Kang ◽  
Sung Il Kang
Keyword(s):  
Rectal Cancer ◽  
Surgical Treatment ◽  
Cancer Patients ◽  
Functional Outcomes

Functional Outcomes and Quality of Life after Redo Anastomosis in Rectal Cancer Patients

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Emma Westerduin ◽  
Hossam Elfeki ◽  
Alice Frontali ◽  
Zaher Lakkis ◽  
Søren Laurberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Cancer Patients ◽  
Functional Outcomes

scholarly journals Prognosis comparison between wait and watch and surgical strategy on rectal cancer patients after treatment with neoadjuvant chemoradiotherapy: a meta-analysis

2019 ◽  
Vol 12 ◽  
pp. 175628481989247 ◽  
Author(s):  
Kai Pang ◽  
Quan Rao ◽  
Shengqi Qin ◽  
Lan Jin ◽  
Hongwei Yao ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Surgical Treatment ◽  
Cancer Patients ◽  
Distant Metastasis ◽  
Meta Analysis ◽  
Neoadjuvant Chemoradiotherapy ◽  
Complete Response ◽  
Prognostic Indicators ◽  
Cochrane Library ◽  
Surgery Group

Background: After achieving a clinical complete response through neoadjuvant chemoradiotherapy, a nonoperative management approach for rectal cancer patients known as Wait and Watch (W&W) has gained increasing attention. However, the W&W strategy has been related to higher local recurrence and ambiguous long-term survival. This meta-analysis compared key prognosis indicators between W&W and surgical treatment in an effort to clarify some long-standing points of confusion. Methods: Pubmed, Web of Science, EMbase, Cochrane Library were searched for relevant researches comparing W&W with surgery treatment, with a time criteria set from 1 January 2002 to 4 July 2019. Endpoints were 2-year local regrowth/recurrence, 2-year distant metastasis (plus local regrowth/recurrence), 3- and 5-year disease-free survival (DFS), and overall survival (OS). Results: In total, nine studies with 801 patients were enrolled, of which 348 were managed by W&W and 453 by surgery. Surgery patients were further divided into a pathological complete response (pCR) group (all included patients achieved pCR) and a surgery group (consisting of both pCR and non-pCR patients without deliberate screening). Compared with the surgery group, W&W patients have higher 3- and 5-year OS, and are not inferior on 2-year local regrowth (LR), 2-year distant metastasis (DM)/DM+LR, and 3- and 5-year DFS. On the other hand, compared with the pCR group, the W&W group is inferior on 2-year LR, 3- and 5-year DFS, and 5-year OS, and not inferior on 2-year DM/DM+LR and 3-year OS. Conclusions: In contrast with patients undergoing surgical treatment, the W&W group has higher 3- and 5-year OS, and is not inferior on other major prognostic indicators, which, however, is based on the fact that the tumor stage in the W&W group is generally earlier. Versus surgically treated patients who acquired pCR, W&W group is inferior on all major prognostic indicators except 2-year DM/DM+LR and 3-year OS. Additionally, by comparison of cCR definitions across different studies, we conclude that implementation of the strictest cCR criteria is critical for W&W patients to acquire maximum prognostic benefit.

scholarly journals CHALLENGES IN THE DIAGNOSIS AND TREATMENT OF PATIENTS WITH COLORECTAL CANCER AND COVID-19 COINFECTION - CASE REPORT

2021 ◽  
Vol 3 (2) ◽  
pp. 160-167
Author(s):  
Vladislav Stoyanov ◽  
◽  
Svetlana Bezhanova
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Case Report ◽  
Surgical Treatment ◽  
Cancer Patients ◽  
Healthy Individuals ◽  
Biological Features ◽  
History Of ◽  
Colorectal Cancer Patients ◽  
Rule Out

Patients with colorectal cancer (CRC) are more likely to become infected with COVID-19 than healthy individuals. The risk of comlications and death in COVID-19 positive colorectal cancer patients is higher due to treatments that suppress the immune system. We discuss a 71-year-old woman with a history of metastatic rectal cancer and underwent surgery and chemotherapy. With no clinical feathers of an acute abdomen or COVID-19 infection. Further researches are needed to rule out if COVID-19 can mask clinical and biological features presentation in cancer patients. Keywords: metastatic colorectal cancer, COVID-19 infection, surgical treatment

M1516 Results of Surgical Treatment of Local Recurrence in Rectal Cancer Patients

2008 ◽  
Vol 134 (4) ◽  
pp. A-864
Author(s):  
Jörn Gröne ◽  
Martin Kruschewski ◽  
Joerg P. Ritz ◽  
Uwe Pohlen ◽  
Hubert G. Hotz ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Surgical Treatment ◽  
Local Recurrence ◽  
Cancer Patients

Utility of EUS to identify the effective responders from rectal cancer patients who receive neo-adjuvant chemotherapy

Endoscopy ◽  
2011 ◽  
Vol 43 (S 03) ◽  
Author(s):  
Zhang Xiaoyin ◽  
Guo Xuegang ◽  
Wang Xin ◽  
Du Jianjun ◽  
Zhao Qingchuan ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Neo Adjuvant Chemotherapy

OUTCOME OF SPHINCTER PRESERVING RECTAL RESECTION FOR LOW RECTAL CANCER

2017 ◽  
pp. 36-40
Author(s):  
Vinh Quy Truong ◽  
Anh Vu Pham ◽  
Quang Thuu Le
Keyword(s):  
Rectal Cancer ◽  
Functional Outcomes ◽  
Low Anterior Resection ◽  
Rectal Resection ◽  
Anal Verge ◽  
Low Rectal Cancer ◽  
Central Hospital ◽  
Mesorectal Excision ◽  
Pull Through ◽  
Stage T1

Purpose: To evaluate the functional outcome of sphincter-preserving rectal resection for low rectal cancer. Materials and Methods: From April 2009 to January 2016, there are 52 patients who underwent sphincter-preserving rectal resection with total mesorectal excision with low rectal cancer (<6cm from the anal verge) at Hue Central Hospital, Hue, Vietnam. Results: the average age 62.7 ± 12.8, the distance of tumor from anal verge include four group (≤ 3cm 1.9%; 3 to ≤ 4cm 17.3%; 4 to ≤ 5cm 34.6%; > 5 cm). T stage T1/ T2/T3: 1.9%/28.8%/69.2%. The following time is 33.8 ± 18.9 month. Overall recurrence was 13/18(27.1%), local recurrence was 5 (10.4%). Total survival was 40.5 ± 2.9 month. Technique: intersphincteric preservation 14 (26.9%), low anterior resection 17 (32.7%) and pull-through procedure 21 (40.4%). The distance of anatomosis from anal verge: from 1 to ≤ 2 cm:14 (26.9%); from 2 to ≤ 3cm: 21 (40.4%); from 3 to ≤ 4 cm: 17 (32.7%). Bowels movement of 3 month: 4.7 ± 3.2 and 12th month: 2.7 ± 1.6 (p< 0.01). Conclusions: Sphincterpreserving rectal resection using may provide a good continence and oncologic safety. The patients are acceptable with the results of functional outcomes. Key words: Low rectal cancer, sphincter-preserving

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