Determination of organic substances by oxidation with potassium permanganate

1974 ◽  
Vol 62 (3) ◽  
pp. 493-501
Author(s):  
A. Berka ◽  
Z. Z�vesk�
Keyword(s):  
Potassium Permanganate ◽  
Organic Substances

Colorimetric Determination of Amoxicillin in Pure and some Pharmaceutical Formulations Via Reaction with Potassium Permanganate as Oxidant Reagent

2019 ◽  
Vol 10 (02) ◽  
Author(s):  
Abbas Shebeeb Al-kadumi ◽  
Sahar Rihan Fadhel ◽  
Mohammed Abdullah Ahmed ◽  
Luma Amer Musa
Keyword(s):  
Potassium Permanganate ◽  
Pharmaceutical Preparations ◽  
Pharmaceutical Formulations ◽  
Atomic Emission ◽  
Basic Medium ◽  
Photometric Method ◽  
Colorimetric Determination ◽  
Spectrophotometric Methods ◽  
Label Claim

We proposed two simple, rapid, and convenient spectrophotometric methods are described for the determination of Amoxicillin in bulk and its pharmaceutical preparations. They are based on the measurement of the flame atomic emission of potassium ion (in first method) and colorimetric determination of the green colored solution for manganite ion at 610 nm formed after reaction of Amoxicillin with potassium permanganate as oxidant agent (in the second method) in basic medium. The working conditions of the methods were investigated and optimized. Beer's law plot showed a good correlation in the concentration range of 5-45 μg/ml. The detection limits and relative standared deviations were (2.573, 2.814 μg/ml) (2.137, 2.498) for the flame emission photometric method and (1.844, 2.016 μg/ml) (1.645,1.932) for colorimetric methods for capsules and suspensions respectively. The methods were successfully applied to the determination of Amoxicillin in capsules and suspensions, and the obtained results were in good agreement with the label claim. No interference was observed from the commonly encountered additives and expectancies.

scholarly journals Determination of lethal concentration and antibacterial activity of commonly used disinfectants

1970 ◽  
Vol 1 (4) ◽  
pp. 102-105 ◽  
Author(s):  
M Alam ◽  
MM Rahman ◽  
MJ Foysal ◽  
MN Hossain
Keyword(s):  
Methylene Blue ◽  
Pseudomonas Fluorescens ◽  
Potassium Permanganate ◽  
Malachite Green ◽  
Copper Sulfate ◽  
Pathogenic Bacteria ◽  
Labeo Rohita ◽  
Inhibitory Effect ◽  
Lethal Concentration

The toxic effects of four disinfectants viz., copper sulfate (CuSO4), potassium permanganate (KMnO4), methylene blue and malachite green on fish and fish pathogenic bacteria Aeromonas sp., Pseudomonas fluorescens, Edwardsiella sp. and Flavobacterium sp. were investigated. Lethal concentration of the disinfectants to fingerlings of Labeo rohita was determined in aquarium by standard method. Lethal concentration of copper sulfate (CuSO4), potassium permanganate (KMnO4), methylene blue and malachite green against fish were found in 0.75ppm, 7ppm, 6ppm and 0.5ppm at 21.4hrs, 18hrs, 9.5hrs and 1.40hrs, respectively. Methylene blue at 4ppm and 5ppm concentration inhibited the growth of Pseudomonas fluorescens and 6ppm concentration suppressed the growth of Aeromonas sp. Copper sulfate (CuSO4) was effective only against Edwardsiella sp at concentration of 10ppm and 8ppm. Malachite green repressed the growth of all four tasted bacteria at a concentration of 1ppm. Potassium permanganate (KMnO4) was failed to exhibit any inhibitory effect on the bacteria even at 30ppm concentration. DOI: http://dx.doi.org/10.3329/ijns.v1i4.9738 IJNS 2011 1(4): 102-105

The Perchloric Method for the Determination of Sulfur in Rubber

1934 ◽  
Vol 7 (4) ◽  
pp. 730-735
Author(s):  
Ernest Kahane
Keyword(s):  
Nitric Acid ◽  
Perchloric Acid ◽  
Organic Substance ◽  
Present Author ◽  
General Idea ◽  
Organic Substances ◽  
Gutta Percha ◽  
Higher Temperature ◽  
As If

Abstract The problem of the determination of sulfur in rubber has been dealt with extensively in the literature, and it seems as if discussions and descriptions of new technic are nowhere nearly ended yet. The determination is so essential, and its rapid and precise execution is of such importance in industrial technic, that efforts in this direction should not be regarded as wasted. In 1926 and in 1927 Le Caoutchouc et La Gutta-Percha contained two articles in which the present author discussed the conditions of the determination of sulfur in rubber and then proposed the use of a new oxidizing mixture, not mentioned previous to that time, which involved the destruction of organic substances by perchloric acid. This method consisted simply in the attack on a 1-gram sample of rubber by 10 cc. of nitric acid (d. 1.39) and 5 cc. of perchloric acid (d. 1.61). Upon heating, attack by the nitric acid takes place, and this is followed by evaporation of the excess nitric acid, then at a little higher temperature there is an attack by the perchloric acid, which oxidizes the rest of the organic substance completely. This publication was concerned much more, in the determination of sulfur by the perchloric method, with the general idea of the destruction of organic substances than it was with the precise details of carrying it out. The technic had been studied somewhat superficially, as is shown by the text of the article itself.

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