scholarly journals 9.14 Relation Between Resting Metabolic Rate and Blood Pressure in Overweight-Obese People: Effect of Gender

2008 ◽  
Vol 15 (3) ◽  
pp. 274-274
Author(s):  
G. Seghieri ◽  
F. Cipollini ◽  
E. Arcangeli ◽  
G. Fabbri ◽  
I. Chiti ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Obese People

scholarly journals The Relationship Between Modified Nordic Diet and Resting Metabolic Rate Among Overweight and Obese Participants: A Cross Sectional Study

2020 ◽  
Author(s):  
Ghazaleh Khalili ◽  
Atieh Mirzababaei ◽  
Farideh Shiraseb ◽  
Khadijeh Mirzaei
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Metabolic Rate ◽  
Body Mass ◽  
Resting Metabolic Rate ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lower Odds ◽  
Nordic Diet

Abstract Objective: Obesity as a worldwide phenomenon is a multifactorial condition. Healthy diets have effect on obesity related factors like resting metabolic rate (RMR). In present study, we investigate association between adherence to modified Nordic diet and RMR among overweight and obese participants.Methods: We enrolled 404 overweight and obese (BMI ≥25 kg/m2) women aged 18-48 years in this cross-sectional study. For each participant anthropometrics measurements, biochemical tests and blood pressure were evaluated. RMR was measured by indirect calorimetry. RMR/kg was also measured. Modified Nordic diet score was measured using a validated 147-item food frequency questionnaire (FFQ).Results: Among all participants, the mean and standard deviation (SD) for age and body mass index (BMI) were 36.67 years (SD=9.10) and 31.26 kg/m2 (SD=4.29). There was a significant association between RMR/kg status and age, body mass index (BMI), RMR (P<0.001), respiratory quotient (RQ), fat percentage (P= 0.01), systolic blood pressure (SBP) (P= 0.03), and diastolic blood pressure (DBP) (P= 0.04), after adjustment for age, BMI, energy intake and physical activity. Participants with the highest adherence to modified Nordic diet had lower odds of hypometabolic status after adjusting for confounders and it was significant (odds ratio (OR) = 3.15, 95% CI= 0.97-10.15, P=0.05).Conclusions: The present results indicate that adherence to modified Nordic diet is associated with lower odds of hypometabolic status in overweight and obese women. However more studies are needed to confirm our findings.

scholarly journals Reduced Cardiovascular Capacity and Resting Metabolic Rate in Men with Prostate Cancer Undergoing Androgen Deprivation: A Comprehensive Cross-Sectional Investigation

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Bradley A. Wall ◽  
Daniel A. Galvão ◽  
Naeem Fatehee ◽  
Dennis R. Taaffe ◽  
Nigel Spry ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Blood Pressure ◽  
Arterial Stiffness ◽  
Oxygen Uptake ◽  
Metabolic Rate ◽  
Androgen Deprivation Therapy ◽  
Maximal Oxygen Uptake ◽  
Resting Metabolic Rate ◽  
Androgen Deprivation ◽  
Cross Sectional

Objectives. To investigate if androgen deprivation therapy exposure is associated with additional risk factors for cardiovascular disease and metabolic treatment-related toxicities.Methods. One hundred and seven men (42–89 years) with prostate cancer undergoing androgen deprivation therapy completed a maximal graded objective exercise test to determine maximal oxygen uptake, assessments for resting metabolic rate, body composition, blood pressure and arterial stiffness, and blood biomarker analysis. A cross-sectional analysis was undertaken to investigate the potential impact of therapy exposure with participants stratified into two groups according to duration of androgen deprivation therapy (<3 months and ≥3 months).Results. Maximal oxygen uptake (26.1 ± 6.0 mL/kg/min versus 23.2 ± 5.8 mL/kg/min,p=0.020) and resting metabolic rate (1795 ± 256 kcal/d versus 1647 ± 236 kcal/d,p=0.005) were significantly higher in those with shorter exposure to androgen deprivation. There were no differences between groups for peripheral and central blood pressure, arterial stiffness, or metabolic profile.Conclusion. Three months or longer exposure to androgen deprivation therapy was associated with reduced cardiorespiratory capacity and resting metabolic rate, but not in a range of blood biomarkers. These findings suggest that prolonged exposure to androgen deprivation therapy is associated with negative alterations in cardiovascular outcomes. Trial registry is:ACTRN12609000200280.

scholarly journals Effects of a Single Dose of BURN-XT™ on Resting Metabolic Rate, Substrate Oxidation, and Various Indices of Affect

2022 ◽  
Vol 5 (1) ◽  
Author(s):  
Michael La Monica ◽  
Tim Ziegenfuss ◽  
Hector Lopez
Keyword(s):  
Blood Pressure ◽  
Single Dose ◽  
Metabolic Rate ◽  
Weight Management ◽  
Resting Metabolic Rate ◽  
Vital Signs ◽  
Resting Energy Expenditure ◽  
Substrate Oxidation ◽  
Double Blind ◽  
Over The Counter

Introduction: Many consumers use dietary supplements in the hopes of increasing energy and burning more calories, which if sustained over time may help accelerate weight loss. The purpose of this clinical trial was to investigate the effects of an over-the-counter thermogenic supplement called Burn-XT™ (BXT) on metabolic rate, substrate oxidation, and various psychometric indices of affect that impact weight management.  Methods: Using a double-blind, placebo-controlled, cross-over design, 16 women and 10 men (29.3 ± 7.3 yr, 169.4 ± 8.6 cm, 75.5 ± 14.3 kg) underwent two testing sessions: placebo (PL) and BXT.  Seated metabolic rate and substrate oxidation, vital signs, and anchored visual analogue scale (VAS) assessments of energy, mood, motivation, focus, fatigue, concentration, and appetite were made before supplementation and hourly for three hours post-ingestion. Two-factor (2x4) factorial ANOVAs and paired sample t-tests (corrected for multiple comparisons) were used for analyses. Results: Significant increases in metabolic rate (oxygen consumption) were noted at 60 minutes in BXT (+11.9 mL O2/min) vs. PL (-2.5 mL O2/min), p = 0.004, d = -0.74.  Only BXT increased metabolic rate compared to baseline at 60 minutes (+11.9 mL O2/min, p = 0.021, d = -0.53) and 120 minutes (+12.1 mL O2/min, p = 0.019, d = -0.54).  The AUC for resting energy expenditure increased more in BXT vs. PL (p = 0.007, d = -0.57).  VAS detected significant improvements in energy, mood, focus, and concentration for BXT vs. PL at 120 and 180 minutes (all p < 0.05, d = -0.58 to -0.68).  In all cases, within-group changes from baseline for these VAS parameters were significant (all p < 0.05, d = -0.76 to -1.38) in BXT but not in PL.  No within or between group differences in appetite, substrate oxidation, or heart rate were noted.  Small (~3-4 mm Hg), but statistically significant (p < 0.05, d = -0.51 to -0.69) increases in diastolic blood pressure were noted in BXT at 60, 120, and 180 min vs. PL; and in systolic blood pressure at 60 min vs. PL. In all cases, values remained within normal clinical hemodynamic ranges. Conclusions: A single dose of BXT safely increased metabolic rate, energy, mood, focus, and concentration. Given that these factors are known to favorably impact weight management, future studies should determine whether daily supplementation with BXT reduces body weight and improves body composition.

Abstract P061: Selective Deletion of Intracellular Renin in the Brain Causes Hypertension and Elevated Sympathetic Nervous System Activity

Hypertension ◽  
2015 ◽  
Vol 66 (suppl_1) ◽  
Author(s):  
Keisuke Shinohara ◽  
Benjamin J Weidemann ◽  
Matthew D Folchert ◽  
Xuebo Liu ◽  
Donald A Morgan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Rate ◽  
Systolic Blood Pressure ◽  
Neural Circuit ◽  
Resting Metabolic Rate ◽  
Renin Angiotensin System ◽  
Power Spectral Analysis ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
The Brain

Renin expression is regulated by two distinct promoter-1st exon combinations that target renin either for secretion (exon 1a for secreted renin) or cytoplasmic retention (exon 1b for intracellular renin, icREN). We developed icREN knockout (KO) mice by selectively deleting exon 1b. icREN KO mice are essentially brain-specific knockouts of icREN because icREN is predominantly expressed in the brain. Notably, systolic blood pressure measured by telemetry was increased in icREN KO mice (130±2 mmHg, n=8 vs 122±2 mmHg in controls, n=7, P<0.01). The low- to high-frequency ratio (LF/HF) derived from power spectral analysis of heart rate variability, a parameter of sympathetic nerve activity (SNA), was increased in icREN KO mice (KO: 1.24±0.21, n=7 vs control: 0.70±0.11, n=7, P<0.05). Body weight (BW) was normal in icREN KO mice compared to controls, but the BW gain and fat accumulation induced by high fat diet (HFD) were attenuated in male icREN KO mice (BW at 16 wks of HFD- KO: 36.8±1.2 g, n=8 vs control: 41.9±1.4 g, n=9; relative fat mass at 14 wks of HFD- KO: 27.7±1.7%, n=8 vs control: 34.4±2.3%, n=9, both P<0.05). The resting metabolic rate measured by respirometry was increased in icREN KO mice (0.156±0.005 kcal/h, n=46, P<0.05) vs controls (0.145±0.003 kcal/h, n=53), whereas food consumption and absorbed calories were not different. We previously reported that the brain renin-angiotensin system facilitates renal SNA (RSNA) response to acute intracerebroventricular (ICV) injection of leptin. Interestingly, the RSNA response to ICV leptin was greater in icREN KO mice (KO: 214±40 % baseline, n=5 vs control: 114±18 % baseline, n=10, P<0.01). AT1a receptor mRNA was upregulated in the paraventricular nucleus of icREN KO mice (P<0.05). Chronic ICV injection of losartan not only abolished the elevated blood pressure in icREN KO mice, but reduced it to below baseline in controls (systolic blood pressure, 111±3 mmHg in KO, n=5; 124±4 mmHg in controls, n=6). These data suggest that icREN deletion increases the activity of brain renin-angiotensin system and elevates blood pressure and metabolic rate through sympathetic activation. We conclude that this novel icREN isoform contributes to cardiovascular and metabolic control possibly as part of an inhibitory neural circuit.

Evaluation of dietary habits and nutritional content of food intake in overweight and obese patients

2014 ◽  
Vol 21 (1) ◽  
pp. 29-35
Author(s):  
Mihaela Posea ◽  
Andreea Dragomir ◽  
Emilia Rusu ◽  
Raluca Nan ◽  
Ramona Draguţ ◽  
...  
Keyword(s):  
Food Intake ◽  
Metabolic Rate ◽  
Body Fat ◽  
Dietary Habits ◽  
Resting Metabolic Rate ◽  
Normal Weight ◽  
Abdominal Circumference ◽  
Obese Patients ◽  
Nutritional Content ◽  
Obese People

Abstract Background and Aims To document the nutritional content of food intake in overweight and obese people, in order to change dietary habits for acquiring the normal weight. Material and methods We assessed the nutritional content of food intake (kilocalories, vitamins and minerals) in a sample of 124 overweight and obese people and 33 subjects with normal weight. We also measured abdominal circumference, percent of body fat and resting metabolic rate. Results Overweight and obese patients, compared to normal weight, have a significant increased intake of vitamin A (p=0.002), vitamin B1 (p=0.037), vitamin B5 (p=0.047), vitamin C (p=0.029) and vitamin D (p=0.015), sodium (p=0.036), iron (p=0.032) and selenium (p=0.007). The percent of body fat in obese persons is increased (p=0.00001) and very close to abnormal in patients with no weight problems. An increased food intake, above the calculated resting metabolic rate, is associated with a slower metabolism and a rapid resting metabolic rate is often associated with food intake below resting metabolic rate (p=0.002). Conclusions All subjects had imbalanced intake of vitamins and minerals. The normal weight group didn’t achieve the dietary recommendations for vitamins and minerals and we found that these subjects had risk factors for cardiac diseases like increased abdominal circumference, body fat and sodium intake.

EFFECT OF AMPHENONE B ON DEVELOPMENT OF RENAL HYPERTENSION IN RATS

1963 ◽  
Vol 41 (8) ◽  
pp. 1703-1712 ◽  
Author(s):  
Melvin J. Fregly ◽  
Robert E. Taylor Jr.
Keyword(s):  
Blood Pressure ◽  
Food Intake ◽  
Thyroid Gland ◽  
Metabolic Rate ◽  
Systolic Blood Pressure ◽  
Release Rate ◽  
Resting Metabolic Rate ◽  
Renal Hypertension ◽  
Thyroid Activity ◽  
Dose Levels

The effect of Amphenone B on development of renal hypertension was studied in rats whose kidneys were encapsulated with latex envelopes. The compound was administered in the diet for 13 weeks at dose levels of 0.1 and 0.3% by weight. Both dose levels of Amphenone B were equally effective in preventing rise of systolic blood pressure to the level of untreated, renal-encapsulated controls although both doses of the drug allowed modest rises of pressure to occur. Growth was inhibited by the drug. Amphenone B depressed thyroid activity as assessed by increased release rate of radioactive iodide from the thyroid gland; decreased resting metabolic rate; decreased growth; decreased food intake; and increased thyroid size. The protection against development of hypertension afforded by this compound may be related, at least in part, to its antithyroid activity.

EFFECT OF AMPHENONE B ON DEVELOPMENT OF RENAL HYPERTENSION IN RATS

1963 ◽  
Vol 41 (1) ◽  
pp. 1703-1712
Author(s):  
Melvin J. Fregly ◽  
Robert E. Taylor Jr.
Keyword(s):  
Blood Pressure ◽  
Food Intake ◽  
Thyroid Gland ◽  
Metabolic Rate ◽  
Systolic Blood Pressure ◽  
Release Rate ◽  
Resting Metabolic Rate ◽  
Renal Hypertension ◽  
Thyroid Activity ◽  
Dose Levels

The effect of Amphenone B on development of renal hypertension was studied in rats whose kidneys were encapsulated with latex envelopes. The compound was administered in the diet for 13 weeks at dose levels of 0.1 and 0.3% by weight. Both dose levels of Amphenone B were equally effective in preventing rise of systolic blood pressure to the level of untreated, renal-encapsulated controls although both doses of the drug allowed modest rises of pressure to occur. Growth was inhibited by the drug. Amphenone B depressed thyroid activity as assessed by increased release rate of radioactive iodide from the thyroid gland; decreased resting metabolic rate; decreased growth; decreased food intake; and increased thyroid size. The protection against development of hypertension afforded by this compound may be related, at least in part, to its antithyroid activity.

Increased resting metabolic rate and lipid oxidation in exercise-trained individuals: evidence for a role of β-adrenergic stimulation

1992 ◽  
Vol 70 (10) ◽  
pp. 1342-1347 ◽  
Author(s):  
Angelo Tremblay ◽  
Serge Coveney ◽  
Jean-Pierre Després ◽  
André Nadeau ◽  
Denis Prud'homme
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Metabolic Rate ◽  
Systolic Blood Pressure ◽  
Lipid Oxidation ◽  
Resting Metabolic Rate ◽  
Cardiovascular Effects ◽  
Adrenergic Stimulation ◽  
Placebo Condition ◽  
Trained Subjects

This study investigated the contribution of β-adrenergic stimulation to the increase in resting metabolic rate (RMR) and lipid oxidation observed in exercise-trained individuals. Nine trained and eight sedentary men were subjected to two testing sessions, during which these variables were measured before and for 3 h after the oral administration of propranolol or placebo. As expected, RMR and lipid oxidation were significantly higher in the trained subjects before the administration of propranolol and throughout the placebo test in comparison with sedentary controls. A significant decrease in RMR and lipid oxidation was induced by propranolol in the trained subjects, whereas no change was observed in the untrained group, and this effect of propranolol was sufficient to abolish the difference between the two groups at baseline and under the placebo condition. Propranolol also induced a significant reduction in heart rate and systolic blood pressure, but the response was comparable in the two groups. In conclusion, the results of this study show that β-adrenergic stimulation is involved in the increase in RMR and lipid oxidation observed in highly trained individuals. Moreover, the absence of a training–propranolol interaction effect on heart rate and systolic blood pressure suggests the existence of some dissociation between the metabolic and cardiovascular effects of prolonged exercise training.Key words: energy expenditure, propranolol, physical activity, catecholamines, heart rate, blood pressure.

scholarly journals The Relationship Between Modified Nordic Diet and Resting Metabolic Rate Among Overweight and Obese Participants: A Cross Sectional Study

2020 ◽  
Author(s):  
Ghazaleh Khalili ◽  
Atieh Mirzababaei ◽  
Farideh Shiraseb ◽  
Khadijeh - Mirzaei
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Metabolic Rate ◽  
Body Mass ◽  
Resting Metabolic Rate ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lower Odds ◽  
Nordic Diet

Abstract Objective: Obesity as a worldwide phenomenon is a multifactorial condition. Healthy diets have effect on obesity related factors like resting metabolic rate (RMR). In present study, we investigate association between adherence to modified Nordic diet and RMR among overweight and obese participants.Methods: We enrolled 404 overweight and obese (BMI ≥25 kg/m2) women aged 18-48 years in this cross-sectional study. For each participant anthropometrics measurements, biochemical tests and blood pressure were evaluated. RMR was measured by indirect calorimetry. RMR/kg was also measured. Modified Nordic diet score was measured using a validated 147-item food frequency questionnaire (FFQ).Results: Among all participants, the mean and standard deviation (SD) for age and body mass index (BMI) were 36.67 years (SD=9.10) and 31.26 kg/m2 (SD=4.29). There was a significant association between RMR/kg status and age, body mass index (BMI), RMR (P<0.001), respiratory quotient (RQ), fat percentage (P= 0.01), systolic blood pressure (SBP) (P= 0.03), and diastolic blood pressure (DBP) (P= 0.04), after adjustment for age, BMI, energy intake and physical activity. Participants with the highest adherence to modified Nordic diet had lower odds of hypometabolic status after adjusting for confounders and it was significant (odds ratio (OR) = 3.15, 95% CI= 0.97-10.15, P=0.05).Conclusions: The present results indicate that adherence to modified Nordic diet is associated with lower odds of hypometabolic status in overweight and obese women. However more studies are needed to confirm our findings.Trial registration: This article was not a trial research.

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