scholarly journals Retrospective analysis of anterior correction and fusion for adolescent idiopathic thoracolumbar/lumbar scoliosis: the relationship between preserving mobile segments and trunk balance

2008 ◽  
Vol 33 (1) ◽  
pp. 191-196 ◽  
Author(s):  
Yang Liu ◽  
Ming Li ◽  
Xiao-Dong Zhu ◽  
Xu-Hui Zhou ◽  
Hua-Jiang Chen ◽  
...  
2021 ◽  
Vol 186 (Supplement_1) ◽  
pp. 502-505
Author(s):  
Justin J Stewart ◽  
Diane Flynn ◽  
Alana D Steffen ◽  
Dale Langford ◽  
Honor McQuinn ◽  
...  

ABSTRACT Introduction Soldiers are expected to deploy worldwide and must be medically ready in order to accomplish their mission. Soldiers unable to deploy for an extended period of time because of chronic pain or other conditions undergo an evaluation for medical retirement. A retrospective analysis of existing longitudinal data from an Interdisciplinary Pain Management Center (IPMC) was used to evaluate the temporal relationship between the time of initial duty restriction and referral for comprehensive pain care to being evaluated for medical retirement. Methods Patients were adults (>18 years old) and were cared for in an IPMC at least once between May 1, 2014 and February 28, 2018. A total of 1,764 patients were included in the final analysis. Logistic regression was used to evaluate the impact of duration between date of first duty restriction documentation and IPMC referral to the outcome variable of establishment of a permanent 3 (P3) profile. Results The duration between date of first duty restriction and IPMC referral showed a curvilinear relationship to probability of a P3 profile. According to our model, a longer duration before referral is associated with an increased probability of a subsequent P3 profile with the highest probability peaking at 19 months. The probability of P3 declines gradually for those who were referred later. Discussion This is the first time the relationship between time of initial duty restriction, referral to an IPMC, and subsequent P3 or higher profile has been tested. Future research is needed to examine medical conditions listed on the profile to see how they might contribute to the cause of referral to the IPMC. Conclusion A longer duration between initial duty restriction and referral to IPMC was associated with higher odds of subsequent P3 status for up to 19 months. Referral to an IPMC for comprehensive pain care early in the course of chronic pain conditions may reduce the likelihood of P3 profile and eventual medical retirement of soldiers.


2019 ◽  
Vol 9 (2) ◽  
pp. 13-34
Author(s):  
María Julia González-Conde ◽  
◽  
Miguel Ángel Ortiz-Sobrino ◽  
Hugo Prieto-González ◽  
◽  
...  

The main objective of this article is to give a contextualization of radio drama in Spain, over a period of three decades in the last century, between the 1940s and the 1970s. Through retrospective analysis on its history some of the keys related to narrative and drama genres implementation are assessed. The research methodology used can be classified as theoretical-conceptual, since it has been based on the search, compilation and analysis of documentation that have allowed radio theater to be contextualized in those three decades. As a result of the research, the relationship between radio plays and social context is revealed and the contributions of the main Spanish authors and directors of radio drama in those decades are referenced. The final conclusion points to the fact that radio drama throughout radio history has been appearing and disappearing conditioned by programmers and public demand. Despite this, even by the end of the seventies, when radio programmers stood up for informative content, some radio dramatic serials would continue in the radio programming: La Saga de los Porretas (Cadena SER) or Sobrenatural and Historias (RNE). Keywords: Radio; Radio Drama; Radio Serials; Radio Soap Opera; Radio Fiction.


2015 ◽  
Vol 36 (3) ◽  
pp. 347-351 ◽  
Author(s):  
Jonas J.-H. Park ◽  
Anmin Shen ◽  
Christina Loberg ◽  
Martin Westhofen

2010 ◽  
Vol 110 (6) ◽  
pp. 595-597 ◽  
Author(s):  
C.-Y. Fu1· ◽  
C.-H. Chu ◽  
T.-P. Liu3· ◽  
Z.-J. Hong ◽  
K.-F. Hsu ◽  
...  

2013 ◽  
Vol 10 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Masamichi Sato ◽  
Yoko Shibata ◽  
Shuichi Abe ◽  
Sumito Inoue ◽  
Akira Igarashi ◽  
...  

2017 ◽  
Vol 33 (5) ◽  
pp. 400-405 ◽  
Author(s):  
Nurliza Abdul Razak ◽  
Rifqah Nordin ◽  
Normastura Abd Rahman ◽  
Roszalina Ramli

Author(s):  
В. Лановая ◽  
V. Lanovaya

The problems arising from the transformation of the pension system are the most relevant in recent years. This article presents a retrospective analysis of pension systems in Russia and Italy. The statistical portrait of the number of pensioners, the dynamics of life expectancy and the number of years in retirement, the coefficient of pension load, the average pension in these countries were studied. Particular attention is paid to the advantages and disadvantages of the functioning of pension systems, the main directions of reform in recent years. The analyzed data allows to substantiate the relationship between statistical indicators explaining the prerequisites of the latest changes in the functioning of pension systems and the directions of their current improvement. The reasoned position regarding the design experience of the organization of the Italian pension system in relation to Russia will avoid a number of problems that can adversely affect not only each individual, but also the development of the whole country.


2013 ◽  
Vol 31 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Alex Alexopoulos ◽  
Talia Kakourou ◽  
Irene Orfanou ◽  
Athina Xaidara ◽  
George Chrousos

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Christine K Kha ◽  
Ellyn Phan ◽  
Nicole Simon

Abstract Diabetic ketoacidosis (DKA) is an acute life-threatening complication of diabetes mellitus. It is responsible for greater than 100,000 hospital admissions per year in the US (1). There are few studies regarding the relationship between drug usage and acute diabetic complications (2). Since 2001, cannabis usage among US adults have more than doubled, as state legal restrictions have eased and attitudes towards cannabis have become more permissive. Cannabis is the most commonly used illicit drug in the US (3). Some studies suggested cannabis usage was associated with improvement in insulin sensitivity and pancreatic beta cell function. Other research demonstrated cannabis usage may contribute to diabetes-related hospitalizations. A retrospective analysis was performed at an urban teaching hospital to examine the relationship between cannabis usage and risk for DKA upon presentation. From March 2017 to February 2019, all non-pregnant patients aged 18 years and older, and who met criteria for DKA admission upon medical records review, were included in the study. Demographics, vitals, biochemistry, and toxicology were evaluated. Overall, 188 admissions for DKA were identified in a total of 130 patients, and 43% (81/188) were readmissions by 23 patients. Illicit substance usage was addressed by history in 72% (135/188) of all admissions, among which 24% (33/135) reported cannabis usage. 36% (67/188) of all admissions, 73% (24/33) of the self-reported cannabis usage group, and 46% (37/81) of the readmissions, underwent general toxicology screening that did not include detection for cannabis. 11% (20/188) of all admissions, 24% (8/33) of the self-reported cannabis usage group, and 16% (13/81) of the readmissions, completed toxicology screening specifically for cannabis. All of the self-reported cannabis usage admissions (33/33) and readmissions (81/81) presented with additional aggravating factors for DKA such as medication noncompliance, polysubstance abuse, and infection. Finally, 20 of the overall 130 patients admitted during this timeframe presented with new onset DKA, where none reported cannabis usage, 20% (4/20) completed general toxicology screening, and none underwent cannabis specific toxicology screening. From the observational retrospective analysis at this hospital, there is a need for awareness about substance abuse screening, especially in adults with a history of recurrent hospital admissions for DKA. Knowledge among health care providers and patient education regarding the effect of cannabis usage on metabolic factors and its diabetes complications, including diabetes self-management at time of drug usage, can be further explored in prospective studies. References: (1) Umpierrez (2006) Diabetes Care, 29(12), 2755-2757. (2) Brown et al., (2017) JAMA, 317(2), 207. (3) Haffajee et al., (2018) NEJM, 379(6), 501-504.


Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 34-35
Author(s):  
Kelly Hughes ◽  
Abdullateef O Abdulkareem ◽  
Niketa Raj ◽  
Adam Barsouk ◽  
Tingting Zhan ◽  
...  

Background Multiple Myeloma (MM) is a plasma cell neoplasm causing a proliferation of monoclonal immunoglobulins that causes end organ damage in the form of hypercalcemia, renal insufficiency, anemia, and lytic bone lesions. Specifically, patients with MM are at risk for developing significant bone disease eventually leading to development of skeletal related events (SRE) (pathological fractures, spinal cord compression, and/or need for radiotherapy or surgery to bone). It is well established that the use of anti-resorptive agents (i.e. Bisphosphonates, Denosumab) lead to fewer bony lesions, less severe bone disease, and fewer SREs. However, while anti-resorptive therapy is recommended for all MM patients undergoing treatment, it is common for initiation of anti-resorptive therapy to be delayed due to the need for dental clearance, clinician preference, or relative contraindications to the medications. Current studies show that this therapy is overall underutilized, likely for similar reasons. However, the effect on SRE with regards to time to initiation of anti-resorptive agent has not been well studied. Herein, we conducted a retrospective analysis to determine if time to anti-resorptive agent has an effect on incidence of SREs. Methods: We performed a retrospective cohort study using our Electronic Health Record system to identify and analyze data of patients with newly diagnosed Multiple Myeloma from July 1st, 2016 until June 30th, 2019 to determine whether time to anti-resorptive therapy affects the incidence of SRE. Patients previously treated with bisphosphonates, and patients not treated with anti-resorptive therapy were excluded. The study's primary endpoint was probability of developing SRE based on time to anti-resorptive therapy. The relationship between incidence of SREs and time to anti-resorptive therapy, sex, age, ISS stage at diagnosis, Area Deprivation Index (ADI), and prior SRE present at diagnosis was analyzed by multivariable Cox proportional hazards model. The cutoff point of anti-resorptive therapy delay was based on the recursive partitioning of univariable Cox model. Results: Three hundred and seventy-five patients with newly diagnosed multiple myeloma patients were identified. In total, 237 patients were included in the final analysis. Demographic information is detailed in the table provided. Of these, 208 patients (88%) used bisphosphonates and 29 (12%) used a RANK ligand inhibitor as their anti-resorptive agent. The median time to therapy was 55 days (IQR 135 days). One hundred twenty four (55%) patients had an SRE present at diagnosis. Forty-one (15.2%) patients developed a new SRE after initiation of anti-resorptive therapy. The model showed that patients who had a delay to anti-resorptive therapy of 31 days or greater had a higher risk of developing SRE after diagnosis (HR 2.49, 95% CI 0.95-6.55, p=0.064). In addition, when comparing ISS II to ISS I, patients with ISS II disease had a higher risk of developing SRE (HR 2.78, 95% CI 1.02-7.57, p=0.045). Conclusions: Patients with longer delays to anti-resorptive therapy had higher risk of developing SRE after diagnosis, however the difference was not statistically significant. One explanation for this may be that starting anti-resorptive therapy at any time point may be more important than time it takes to start therapy in the setting of effective anti-myeloma treatment. However, the rate of SRE in this study was lower than initially predicted based on previous studies, and therefore, our sample size may have been too small to detect a significant outcome related to time to initiation of anti-resorptive agents. Ongoing efforts to increase the sample size through multi-institutional initiatives are underway. Disclosures Binder: Janssen: Membership on an entity's Board of Directors or advisory committees; Sanofi: Consultancy.


Sign in / Sign up

Export Citation Format

Share Document