Case–Control Study of Papillary Thyroid Carcinoma on Urinary and Dietary Iodine Status in South Korea

2017 ◽  
Vol 42 (5) ◽  
pp. 1424-1431 ◽  
Author(s):  
Joon-Hyop Lee ◽  
Ra-Yeong Song ◽  
Jin Wook Yi ◽  
Hyeong Won Yu ◽  
Hyungju Kwon ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
South Korea ◽  
Case Control Study ◽  
Case Control ◽  
Papillary Thyroid ◽  
Iodine Status ◽  
Control Study

scholarly journals Association of RET Genetic Polymorphisms and Haplotypes with Papillary Thyroid Carcinoma in the Portuguese Population: A Case-Control Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e109822 ◽  
Author(s):  
Marina Santos ◽  
Teresa Azevedo ◽  
Teresa Martins ◽  
Fernando J. Rodrigues ◽  
Manuel C. Lemos
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Genetic Polymorphisms ◽  
Case Control Study ◽  
Case Control ◽  
Papillary Thyroid ◽  
Portuguese Population ◽  
Control Study

scholarly journals Association of Parental Consanguinity With Papillary Thyroid Carcinoma: A Case-Control Study

2021 ◽  
Author(s):  
Ayman A Zayed ◽  
Justin Z Amarin ◽  
Abdallah T Al-Ani ◽  
Tareq L Altell ◽  
Sultan S Abdelhamid ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Parental Education ◽  
Case Control Study ◽  
Genetic Alterations ◽  
Case Control ◽  
Healthy Controls ◽  
Papillary Thyroid ◽  
Parental Consanguinity ◽  
Control Study

Abstract Context Papillary thyroid carcinoma (PTC) is the most common type of nonmedullary thyroid carcinoma. Uncommonly, PTC is associated with multiple genetic alterations and chromosomal abnormalities and displays familial patterns of inheritance. Parental consanguinity increases susceptibility to many genetic disorders. Objective This work aimed to investigate the association of parental consanguinity with PTC. Methods This case-control study of PTC patients compared with healthy controls took place in a tertiary referral hospital. We recruited 200 PTC patients who were managed at the endocrinology outpatient clinics of the Jordan University Hospital, and we recruited 515 healthy controls from a nonclinical setting. We interviewed all participants and collected sociodemographic data. We reviewed the family pedigrees of each participant four generations back and excluded any participant who was related. We established whether the parents of each participant were first cousins, first cousins once removed, second cousins, or unrelated. We then used binary logistic regression to assess the association of parental consanguinity with PTC adjusted for age, sex, smoking status, body mass index, and parental education. Results We recruited 715 participants. The numbers of PTC patients and healthy controls were 200 (28.0%) and 515 (72.0%), respectively. The rate of parental consanguinity was 25.5% in PTC patients and 12.2% in healthy controls. Parental consanguinity was significantly associated with PTC (adjusted odds ratio, 2.60; 95% CI, 1.63-4.17; P < .001). Conclusion Parental consanguinity is a risk factor for PTC. Our findings should be considered during familial risk assessment and genetic counseling, especially in populations with high rates of consanguinity.

Mortality from papillary thyroid carcinoma: A case-control study of 56 lethal cases

Cancer ◽  
1988 ◽  
Vol 62 (7) ◽  
pp. 1381-1388 ◽  
Author(s):  
Steven A. Smith ◽  
Ian D. Hay ◽  
John R. Goellner ◽  
John J. Ryan ◽  
William M. McConahey
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Papillary Thyroid ◽  
Control Study

Multiple HABP2 variants in familial papillary thyroid carcinoma: A case-control study

2016 ◽  
Vol 77 (4) ◽  
pp. 262
Author(s):  
P. Pigny ◽  
M. Crépin ◽  
C. Do Cao ◽  
J.L. Wemeau ◽  
C. Cardot Bauters ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Papillary Thyroid ◽  
Control Study

scholarly journals Varicella and Varicella Vaccination in South Korea

2014 ◽  
Vol 21 (5) ◽  
pp. 762-768 ◽  
Author(s):  
Sung Hee Oh ◽  
Eun Hwa Choi ◽  
Seon Hee Shin ◽  
Yun-Kyung Kim ◽  
Jin Keun Chang ◽  
...  
Keyword(s):  
South Korea ◽  
Case Control Study ◽  
Varicella Vaccine ◽  
Case Control ◽  
Vaccine Uptake ◽  
Varicella Vaccination ◽  
Healthy Children ◽  
Safety Study ◽  
Control Study ◽  
Case Based

ABSTRACTWith continuing occurrence of varicella despite increasing vaccine coverage for the past 20 years, a case-based study, a case-control study, and an immunogenicity and safety study were conducted to address the impact of varicella vaccination in South Korea. Varicella patients under the age of 16 years were enrolled for the case-based study. For the case-control study, varicella patients between 12 months and 15 years of age were enrolled with one control matched for each patient. For the immunogenicity and safety study, otherwise healthy children from 12 to 24 months old were immunized with Suduvax (Green Cross, South Korea). Fluorescent antibody to membrane antigen (FAMA) varicella-zoster virus (VZV) antibody was measured before and 6 weeks after immunization. In the case-based study, the median age of the patients was 4 years. Among 152 patients between 1 and 15 years of age, 139 children received varicella vaccine and all had breakthrough infections. Clinical courses were not ameliorated in vaccinated patients, but more vaccinated patients received outpatient rather than inpatient care. In the case-control study, the adjusted overall effectiveness of varicella vaccination was 54%. In the immunogenicity and safety study, the seroconversion rate and geometric mean titer for FAMA antibody were 76.67% and 5.31. Even with increasing varicella vaccine uptake, we illustrate no upward age shift in the peak incidence, a high proportion of breakthrough disease, almost no amelioration in disease presentation by vaccination, and insufficient immunogenicity of domestic varicella vaccine. There is need to improve the varicella vaccine used in South Korea.

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