Bariatric Embolization in the Treatment of Patients with a Body Mass Index Between 30 and 39.9 kg/m2 (Obesity Class I and II) and Metabolic Syndrome, a Pilot Study

Author(s):  
Raphael Braz Levigard ◽  
Henrique Serrão ◽  
Camille Castro ◽  
Priscila Matos ◽  
Fernanda Mattos ◽  
...  
2018 ◽  
Vol 128 (4) ◽  
pp. 774-783 ◽  
Author(s):  
Alexander J. Butwick ◽  
Anisha Abreo ◽  
Brian T. Bateman ◽  
Henry C. Lee ◽  
Yasser Y. El-Sayed ◽  
...  

Abstract Background It is unclear whether obesity is a risk factor for postpartum hemorrhage. The authors hypothesized that obese women are at greater risk of hemorrhage than women with a normal body mass index. Methods The authors conducted a cohort study of women who underwent delivery hospitalization in California between 2008 and 2012. Using multilevel regression, the authors examined the relationships between body mass index with hemorrhage (primary outcome), atonic hemorrhage, and severe hemorrhage (secondary outcomes). Stratified analyses were performed according to delivery mode. Results The absolute event rate for hemorrhage was 60,604/2,176,673 (2.8%). In this cohort, 4% of women were underweight, 49.1% of women were normal body mass index, 25.9% of women were overweight, and 12.7%, 5.2%, and 3.1% of women were in obesity class I, II, and III, respectively. Compared to normal body mass index women, the odds of hemorrhage and atonic hemorrhage were modestly increased for overweight women (hemorrhage: adjusted odds ratio [aOR], 1.06; 99% CI, 1.04 to 1.08; atonic hemorrhage: aOR, 1.07; 99% CI, 1.05 to 1.09) and obesity class I (hemorrhage: aOR, 1.08; 99% CI, 1.05 to 1.11; atonic hemorrhage; aOR, 1.11; 99% CI, 1.08 to 1.15). After vaginal delivery, overweight and obese women had up to 19% increased odds of hemorrhage or atonic hemorrhage; whereas, after cesarean delivery, women in any obesity class had up to 14% decreased odds of severe hemorrhage. Conclusions The authors’ findings suggest that, at most, maternal obesity has a modest effect on hemorrhage risk. The direction of the association between hemorrhage and body mass index may differ by delivery mode.


Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1976 ◽  
Author(s):  
Francesco Landi ◽  
Riccardo Calvani ◽  
Anna Picca ◽  
Matteo Tosato ◽  
Anna Maria Martone ◽  
...  

The present study was undertaken to provide a better insight into the relationship between different levels of body mass index (BMI) and changing risk for hypertension, using an unselected sample of participants assessed during the Longevity Check-up 7+ (Lookup7+) project. Lookup7+ is an ongoing cross-sectional survey started in June 2015 and conducted in unconventional settings (i.e., exhibitions, malls, and health promotion campaigns) across Italy. Candidate participants are eligible for enrolment if they are at least 18 years of age and provide written informed consent. Specific health metrics are assessed through a brief questionnaire and direct measurement of standing height, body weight, blood glucose, total blood cholesterol, and blood pressure. The present analyses were conducted in 7907 community-living adults. According to the BMI cutoffs recommended by the World Health Organization, overweight status was observed among 2896 (38%) participants; the obesity status was identified in 1135 participants (15%), with 893 (11.8%) participants in class I, 186 (2.5%) in class II, and 56 (0.7%) in class III. Among enrollees with a normal BMI, the prevalence of hypertension was 45% compared with 67% among overweight participants, 79% in obesity class I and II, and up to 87% among participants with obesity class III (p for trend < 0.001). After adjusting for age, significantly different distributions of systolic and diastolic blood pressure across BMI levels were consistent. Overall, the average systolic blood pressure and diastolic blood pressure increased significantly and linearly across BMI levels. In conclusion, we found a gradient of increasing blood pressure with higher levels of BMI. The fact that this gradient is present even in the fully adjusted analyses suggests that BMI may cause a direct effect on blood pressure, independent of other clinical risk factors.


Author(s):  
L.M. Kolinko

Along with the excess food consumption and the sedentary lifestyle, dysregulation of eating behaviour contributes much to the development of overweight and obesity and often becomes a component of pathogenesis in the number of diseases and conditions. The purpose of this study was to determine the characteristics of eating behaviour in young people with normal body weight, overweight and with obesity class I. The study included 96 individuals aged 18–25. There were evaluated anthropometric parameters and the body fat percentage by the circumference measuring. Based on the body mass index, all subjects were divided into 3 sex-balanced groups of 32 individuals in each: a group with body mass index ranging from 18,5 to 24,9 kg/m2, a group with increased body weight (body mass index from 25,00 to 29,99 kg/m2), and a group with obese class I individuals (body mass index from 30,00 to 34,99 kg/m2). A Dutch Eating behaviour Questionnaire and a 3-factor Stunkard, Three-factor Eating questionnaire - 18 were used to assess eating behaviour. The results were processed statistically. Results. According to the findings obtained by using the Dutch Eating behaviour Questionnaire, the restrictive type of eating disorders was more prevalent in male individuals with obesity class I and in female individuals of all groups. The external type was more pronounced in the men of all groups studied. According to the findings of Three-factor Eating questionnaire - 18, the cognitive restriction type was found as a dominant type of eating behavioural disorders. Between the indicators of eating disorder types according to the Dutch Eating behaviour Questionnaire and Three-factor Eating questionnaire - 18 and anthropometric indicators there has been found mainly positive correlation of high and medium strength in the individuals with normal weight, while the negative correlation of high and medium strength has been detected in the overweight and obese individuals of both sexes. The results obtained point out the need in individualized approach in modifications of the dietary pattern in young people, the importance of mandatory psychological correction, and their combining with other components of weight loss strategies.


Pancreas ◽  
2017 ◽  
Vol 46 (3) ◽  
pp. 358-365 ◽  
Author(s):  
Johan Staaf ◽  
Viktor Labmayr ◽  
Katharina Paulmichl ◽  
Hannes Manell ◽  
Jing Cen ◽  
...  

2010 ◽  
Vol 63 (9-10) ◽  
pp. 611-615 ◽  
Author(s):  
Branka Koprivica ◽  
Teodora Beljic-Zivkovic ◽  
Tatjana Ille

Introduction. Insulin resistance is a well-known leading factor in the development of metabolic syndrome. The aim of this study was to evaluate metabolic effects of metformin added to sulfonylurea in unsuccessfully treated type 2 diabetic patients with metabolic syndrome. Material and methods. A group of thirty subjects, with type 2 diabetes, secondary sulfonylurea failure and metabolic syndrome were administered the combined therapy of sulfonylurea plus metformin for six months. Metformin 2000 mg/d was added to previously used sulfonylurea agent in maximum daily dose. Antihypertensive and hypolipemic therapy was not changed. The following parameters were assessed at the beginning and after six months of therapy: glycemic control, body mass index, waist circumference, blood pressure, triglycerides, total cholesterol and its fractions, homeostatic models for evaluation of insulin resistance and secretion (HOMA R, HOMA B) and C- peptide. Results. Glycemic control was significantly improved after six months of the combined therapy: (fasting 7.89 vs. 10.61 mmol/l. p<0.01; postprandial 11.12 vs. 12.61 mmol/l. p<0.01, p<0.01; glycosylated hemoglobin 6.81 vs. 8.83%. p<0.01). the body mass index and waist circumference were significantly lower (26.7 vs. 27.8 kg/m2, p<0.01 and 99.7 vs. 101.4 cm for men, p<0.01; 87.2 vs. 88.5 for women, p<0.01). Fasting plasma triglycerides decreased from 3.37 to 2.45 mmol/l (p<0.001) and HOMA R from 7.04 to 5.23 (p<0.001). No treatment effects were observed on blood pressure, cholesterol, and residual insulin secretion. Conclusion. Administration of metformin in type 2 diabetes with metabolic syndrome decreased cardiovascular risk factors by reducing glycemia, triglycerides, BMI, central obesity and insulin resistance.


2014 ◽  
Vol 6 (1) ◽  
pp. 1 ◽  
Author(s):  
Mário Nora ◽  
Marta Guimarães ◽  
Rui Almeida ◽  
Paulo Martins ◽  
Gil Gonçalves ◽  
...  

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