scholarly journals Honeycomb sterna: an unusual case of a developmental abnormality in the sternum

2019 ◽  
Vol 42 (1) ◽  
pp. 91-94
Author(s):  
Cara Stella Hirst ◽  
S. White ◽  
T. Siek ◽  
A. Gasparik
Keyword(s):  
Large Scale ◽  
Unusual Case ◽  
Developmental Abnormality ◽  
Developmental Abnormalities ◽  
Anatomical Variants ◽  
Anatomical Specimen ◽  
Clinical Literature ◽  
University College London ◽  
The Individual ◽  
Ct Studies

Abstract This report details an unusual case of a human sternal developmental abnormality of an anatomical specimen part of the skeletal collection curated by University College London, Anthropology Department skeletal collection. This rarely reported developmental abnormality is caused by the non-fusion of lateral ossification centres in the sternebrae, resulting in the mesosternum having a honeycomb-like appearance. Sternal defects are typically underreported in the clinical literature as many cases being asymptomatic that they are typically diagnosed incidentally, as such there is a dearth in our current understanding of the development and anatomical variants of the sternum. Although in recent years, large-scale CT studies have investigated the prevalence of sternal developmental abnormalities, these studies have not reported sternal defects similar to the individual presented in this report. While most sternal defects are clinically uneventful, the lack of awareness of these variants can result in misinterpretation of radiological and pathological findings as such an understanding of anatomical variants even when asymptomatic is vital.

A UNIQUE DISORDER OF THE STERNUM : HONEYCOMB STERNA

2021 ◽  
pp. 20-22
Author(s):  
Santosh Kumar ◽  
Makardhaj Prasad
Keyword(s):  
Large Scale ◽  
Anatomical Variations ◽  
Developmental Anomaly ◽  
Developmental Anomalies ◽  
Anatomical Variants ◽  
Medical College ◽  
The Past ◽  
Anatomical Specimen ◽  
Clinical Literature

This article describes an uncommon example of a human sternal developmental anomaly in an anatomical specimen from the Department of Anatomy at Shahid Nirmal Mahto Medical College Dhanbad. The non-fusion of lateral ossication centres in the sternebrae caused the uncommonly recognized developmental anomaly, which results in a honeycomb-like appearance of the mesosternum. Sternal deciencies are normally under diagnosed in the clinical literature due to the fact that many instances are asymptomatic. As a result, there is a gap in our modern understanding of the development and anatomical variations of the sternum. Although in the past, large-scale CT investigations have been conducted to explore the incidence of sternal developmental anomalies. A very rare work has been reported on sternal malformations. Most of the sternal abnormalities are clinically insignicant; a lack of awareness of these variants can lead to interpretation of radiological and pathological evidence. Hence, anatomical variants are asymptomatic which is vital in nature.

Models, Practices and Methods of Reading: Evolution in Time and Space

2009 ◽  
pp. 59-64
Author(s):  
Yulia P. Melentyeva
Keyword(s):  
Large Scale ◽  
Social Groups ◽  
National Program ◽  
Time And Space ◽  
Lack Of Information ◽  
The Individual

In recent years as public in general and specialist have been showing big interest to the matters of reading. According to discussion and launch of the “Support and Development of Reading National Program”, many Russian libraries are organizing the large-scale events like marathons, lecture cycles, bibliographic trainings etc. which should draw attention of different social groups to reading. The individual forms of attraction to reading are used much rare. To author’s mind the main reason of such an issue has to be the lack of information about forms and methods of attraction to reading.

Flexibility Effects in a Single Link Robotic Manipulator

1993 ◽  
Author(s):  
C. Nataraj
Keyword(s):  
Large Scale ◽  
Robotic Manipulator ◽  
Flexible Beam ◽  
Rotating Speed ◽  
Weighted Residuals ◽  
Individual Interaction ◽  
Single Link ◽  
Rigid Mass ◽  
The Individual ◽  
Future Work

Abstract A single link robotic manipulator is modeled as a rotating flexible beam with a rigid mass at the tip and accurate energy expressions are derived. The resulting partial differential equations are solved using an approximate method of weighted residuals. From the solutions, coupling between axial and flexural deformations and the interactions with rigid body motions are rigorously analyzed. The emphasis in the current paper is not on an exhaustive analysis of existing systems but it is rather intended to compare and highlight the various flexibility effects in a relatively simple system. Hence, a nondimensional parametric analysis is performed to determine the effect of several parameters (including the rotating speed) on the errors and the individual interaction effects are discussed. Comparison with previous work in the field shows important phenomena often ignored or buried in large scale numerical analyses. Future work including application to multi-link robots is outlined.

Structuring the Wider Environment and the DBT Team

2018 ◽  
pp. 216-234
Author(s):  
Michaela A. Swales ◽  
Christine Dunkley
Keyword(s):  
Clinical Experience ◽  
Implementation Research ◽  
Dialectical Tensions ◽  
Behaviour Therapy ◽  
Dialectical Behaviour Therapy ◽  
The Core ◽  
Clinical Literature ◽  
Consultation Team ◽  
The Individual

The role of the dialectical behaviour therapy (DBT) team lead is rarely discussed in the DBT academic or clinical literature. However, much implementation research and clinical experience in training and supporting teams new to DBT indicates the importance of the team lead to the correct and efficient functioning of the team itself. This chapter outlines the role of the team lead in relation to two of the functions of DBT; structuring the environment, and enhancing therapists’ capabilities and motivation. It outlines and discusses the core tasks of each of these functions for the team lead. Additionally, it describes the skills and strategies team leads need to learn and deploy to their team in the individual therapeutic and consultation team settings. Lastly, it outlines common dialectical tensions that can arise for team leads, and offers strategies for their management.

scholarly journals HUMAN ENERGY UTILIZATION AND EFFECTIVENESS IN SMALL AND MARGINAL FARM HOLDINGS

2018 ◽  
Vol 6 (11) ◽  
pp. 163-171
Author(s):  
Tandra Mondal ◽  
Pranab Kumar Nag
Keyword(s):  
Large Scale ◽  
Energy Utilization ◽  
Hand Tools ◽  
Present Contribution ◽  
Land Preparation ◽  
Farm Work ◽  
Farm Mechanization ◽  
Power Tiller ◽  
Paddy Cultivation ◽  
The Individual

In India, small and marginal farmers have emerged as a distinct and dominant category. While farm mechanization represents a rapid transformation from traditional to modern methods of farming, it is not uniform across the crops and regions. The level of mechanization, however, remains scattered due to the compulsiveness to the situation dominated by the economic layout of farm holdings, land size, and large-scale deprivation of access to the technology suitable to small holdings. This present contribution elucidates the extent of use tools and machinery among the rice farmers of the state of Wes Bengal, India. Analysis revealed that the total number of man-days involved in paddy cultivation was 120-140 per ha, i.e., 900-1000 man-hours depending upon the availability of labour, tools, and machinery used for the individual operation. Analysis of farm work in small and marginal holdings evolved that over 90% of the total number of farmers use either tractor or power tiller for land preparation. Use of the animal-drawn country plough is gradually phased out in the study regions. For sowing and transplanting operations are primarily manual methods using hand tools. The study provided an insight of the issues of work methods and practices of the farmworkers in small and marginal farm holdings.

scholarly journals Making Soup: Preparing and Validating Molecular Simulations of the Bacterial Cytoplasm

2019 ◽  
Author(s):  
Leandro Oliveira Bortot ◽  
Zahedeh Bashardanesh ◽  
David van der Spoel
Keyword(s):  
Large Scale ◽  
Biological Properties ◽  
Computational Power ◽  
E Coli ◽  
Solvent Models ◽  
Explicit Solvent ◽  
Computational Modeling And Simulation ◽  
Dynamics Simulations ◽  
The Individual ◽  
Bacterial Cytoplasm

Biomolecular crowding affects the biophysical and biochemical behavior of macro- molecules when compared to the dilute environment present in experiments made with isolated proteins. Computational modeling and simulation are useful tools to study how crowding affects the structural dynamics and biological properties of macromolecules. As computational power increased, modeling and simulating large scale all-atom explicit solvent models of the prokaryote cytoplasm become possible. In this work, we build an atomistic model of the cytoplasm of Escherichia coli composed of 1.5 million atoms and submit it to a total of 3 μs of molecular dynamics simulations. The properties of biomolecules under crowding conditions are compared to those from simulations of the individual compounds under dilute conditions. The simulation model is found to be consistent with experimental data about the diffusion coefficient and stability of macromolecules under crowded conditions. In order to stimulate further work we provide a Python script and a set of files that enables other researchers to build their own E. coli cytoplasm models to address questions related to crowding.<br>

scholarly journals Nonlinear visuoauditory integration in the mouse superior colliculus

2021 ◽  
Author(s):  
Shinya Ito ◽  
Yufei Si ◽  
Alan M. Litke ◽  
David A. Feldheim
Keyword(s):  
Superior Colliculus ◽  
Sensory Integration ◽  
Large Scale ◽  
Temporal Dynamics ◽  
Critical Role ◽  
Sensory Information ◽  
Population Level ◽  
Object Identification ◽  
Response Properties ◽  
The Individual

AbstractSensory information from different modalities is processed in parallel, and then integrated in associative brain areas to improve object identification and the interpretation of sensory experiences. The Superior Colliculus (SC) is a midbrain structure that plays a critical role in integrating visual, auditory, and somatosensory input to assess saliency and promote action. Although the response properties of the individual SC neurons to visuoauditory stimuli have been characterized, little is known about the spatial and temporal dynamics of the integration at the population level. Here we recorded the response properties of SC neurons to spatially restricted visual and auditory stimuli using large-scale electrophysiology. We then created a general, population-level model that explains the spatial, temporal, and intensity requirements of stimuli needed for sensory integration. We found that the mouse SC contains topographically organized visual and auditory neurons that exhibit nonlinear multisensory integration. We show that nonlinear integration depends on properties of auditory but not visual stimuli. We also find that a heuristically derived nonlinear modulation function reveals conditions required for sensory integration that are consistent with previously proposed models of sensory integration such as spatial matching and the principle of inverse effectiveness.

scholarly journals Parallel Distributed Networks Resolved at High Resolution Reveal Close Juxtaposition of Distinct Regions

2018 ◽  
Author(s):  
Rodrigo M. Braga ◽  
Koene R. A. Van Dijk ◽  
Jonathan R. Polimeni ◽  
Mark C. Eldaief ◽  
Randy L. Buckner
Keyword(s):  
High Resolution ◽  
Large Scale ◽  
Spatial Separation ◽  
Distributed Networks ◽  
Association Cortex ◽  
Default Network ◽  
Network Organization ◽  
Parahippocampal Cortex ◽  
The Individual ◽  
Insight Into

Examination of large-scale distributed networks within the individual reveals details of cortical network organization that are absent in group-averaged studies. One recent discovery is that a distributed transmodal network, often referred to as the ‘default network’, is comprised of two separate but closely interdigitated networks, only one of which is coupled to posterior parahippocampal cortex. Not all studies of individuals have identified the same networks and questions remain about the degree to which the two networks are separate, particularly within regions hypothesized to be interconnected hubs. Here we replicate the observation of network separation across analytical (seed-based connectivity and parcellation) and data projection (volume and surface) methods in 2 individuals each scanned 31 times. Additionally, 3 individuals were examined with high-resolution fMRI to gain further insight into the anatomical details. The two networks were identified with separate regions localized to adjacent portions of the cortical ribbon, sometimes inside the same sulcus. Midline regions previously implicated as hubs revealed near complete spatial separation of the two networks, displaying a complex spatial topography in the posterior cingulate and precuneus. The network coupled to parahippocampal cortex also revealed a separate region directly within the hippocampus at or near the subiculum. These collective results support that the default network is composed of at least two spatially juxtaposed networks. Fine spatial details and juxta-positions of the two networks can be identified within individuals at high resolution, providing insight into the network organization of association cortex and placing further constraints on interpretation of group-averaged neuroimaging data.

World War I Conscription and Social Change in Guinea

1978 ◽  
Vol 19 (1) ◽  
pp. 25-38 ◽  
Author(s):  
Anne Summers ◽  
R. W. Johnson
Keyword(s):  
Social Change ◽  
World War I ◽  
Large Scale ◽  
World War ◽  
Political Movement ◽  
Railway Line ◽  
Military Conscription ◽  
Social Grouping ◽  
The Moment ◽  
The Individual

When the French government introduced military conscription into the A.O.F. in 1912, the Guinean colonial authorities saw the measure as a means of training a local administrative corps to replace the traditional chieftaincy, through whose military defeat the conquest of Guinea had very largely been effected. However, the chiefs had by no means disappeared by 1914, and wartime demands for recruits were too massive to be supplied without their assistance. Their help was bought with promises to consolidate their authority in peacetime. Although able to marshal recruits, the chiefs seem to have been unable to prevent large-scale desertions before the moment of embarkation for France; village populations could also avoid conscription by overland migration out of the A.O.F. The colonial authorities therefore felt constrained to offer substantial inducements, mainly concerning improved social status vis-à-vis the chiefs, to the individual recruits. These contradictory policies were compounded by the recruitment drive of Blaise Diagne in 1918, which involved a further promise to recruits of improved status vis-à-vis the French authorities. The return of ancien combattants to Guinea was marked by outbreaks of strike action among workers in Conakry and along the railway line; by riots in demobilization camps; and by rejection of or agitation against chiefly power in the home cantons to which they dispersed. The anciens combattants did not form a coherent or organized political movement, but remained a conspicuous social grouping between the wars. Although they appear to have been strongly influenced by their experience of war and by contact with French socialists, their conflict with the chiefs seems to have counted for more with them than any confrontation with the French.

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