scholarly journals Model curriculum of the German society for Rheumatology for advanced training in the discipline internal medicine and rheumatology. English version

Author(s):  
Alexander Pfeil ◽  
Martin Krusche ◽  
Diana Vossen ◽  
Michael N. Berliner ◽  
Gernot Keyßer ◽  
...  
Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 42-42
Author(s):  
Carolin Jakob ◽  
Aurélie Bauquet ◽  
Renaud Buffet ◽  
Maria Vehreschild ◽  
Janne Vehreschild

Background:Because bacterial infections are a common complication during neutropenia and a major cause for morbidity and mortality, patients with Acute Myeloid Leukaemia (AML) often receive prolonged courses of broad-spectrum antibiotics during induction chemotherapy. This extended exposure to antibiotics deeply disrupts the gut microbiota and may result in its colonization by resistant, opportunistic and potentially pathogenic microbes.Clostridioides difficile (C.difficile)is one such bacteria often found in patients whose microbiota has been strongly disrupted. Aim:The purpose of this study was to measure the incidence ofC. difficileinfection (CDI) in newly diagnosed AML patients who received induction chemotherapy and to evaluate the association between CDI and the use of antibiotics. Methods:We retrospectively studied the medical history of patients treated from 01/2016 to 12/2018 at the Department of Internal Medicine I of the University Hospital Cologne. The observational period was defined as 100 successive days after onset of induction chemotherapy or from onset of induction chemotherapy until microbiological confirmed CDI, or until death, whichever event occurred first. The diagnosis of CDI was confirmed by microbiological findings indicating the presence of toxin-producingC. difficilein stool isolates of symptomatic patients. The associations between therapeutic and prophylactic antibiotics and CDI were determined by use of a multivariable backward-stepwise binary logistic regression model. Findings:133 patients were included in the study. 30 patients developed CDI during the study period. 5 patients had two episodes or more. The incidence rate for CDI per 10,000 patient days in the observational period was 29.9. The incidence rates of CDI for the period after onset of induction chemotherapy reached 10.5% (n=14) at 8 weeks and 18.8% (n=25) at 120 days. In the analysis, we could not identify a specific antibiotic as risk factor for CDI but the result may be biased by the different mean observational periods for the group with and without CDI (the observational period for the group with CDI ends at the day of CDI). Conclusions:CDI is a frequent comorbidity affecting patients with newly diagnosed AML and receiving induction chemotherapy and deserves the attention of the medical teams in charge of the patients for adequate prevention and treatment approaches. Disclosures Bauquet: Da Volterra:Current Employment.Buffet:Da Volterra:Current Employment;Alfa Collaborative Group:Current Employment.Vehreschild:Berlin Chemie:Consultancy, Honoraria;Organobalance:Research Funding, Speakers Bureau;Pfizer:Research Funding, Speakers Bureau;Da Volterra:Research Funding;Seres Therapeutics:Research Funding;Astellas Pharma:Consultancy, Honoraria, Research Funding, Speakers Bureau;3M:Research Funding;Gilead:Research Funding, Speakers Bureau;MSD/Merck:Consultancy, Honoraria, Research Funding, Speakers Bureau;Basilea:Speakers Bureau.Vehreschild:Rigshospitalet Copenhagen:Research Funding;Academy for Infectious Medicine:Honoraria;University Manchester:Honoraria;German Society for Infectious Diseases (DGI):Honoraria;Ärztekammer Nordrhein:Honoraria;University Hospital Aachen:Honoraria;Back Bay Strategies:Honoraria;German Society for Internal Medicine (DGIM):Honoraria;Merck / MSD:Research Funding;Gilead:Research Funding;Pfizer:Research Funding;Astellas Pharma:Research Funding;Basilea:Research Funding;German Centre for Infection Research (DZIF):Research Funding;), German Federal Ministry of Education and Research (BMBF):Research Funding;(PJ-T: DLR):Research Funding;University of Bristol:Research Funding;Merck/MSD:Honoraria;Gilead:Honoraria;Pfizer:Honoraria;Astellas Pharma:Honoraria;Basilea:Honoraria;German Centre for Infection Research (DZIF):Honoraria;University Hospital Freiburg/ Congress and Communication:Honoraria.


2015 ◽  
Vol 128 (9) ◽  
pp. 1039-1043 ◽  
Author(s):  
J. Christian Barrett ◽  
Richard Alweis ◽  
Michael Frank ◽  
Alec O'Connor ◽  
John F. McConville ◽  
...  

2017 ◽  
Vol 142 (24) ◽  
pp. 1862-1867 ◽  
Author(s):  
Ralf Forsbach ◽  
Hans-Georg Hofer

Abstract51 years after its founding in 1882, the "Congress for Internal Medicine", 1920 renamed "German Society for Internal Medicine (DGIM)", fell into heavy water. While during the Kaiserreich and the Weimar Republic the medical care for the individual patient had never been seriously questioned, the proclaimed “Third Reich” brought fundamental changes. The 1164 male and 13 female physicians, who had been organized in the DGIM 1933, had to position themselves in the Nazi dictatorship. The same applied for the society as a whole.The behavior of the German Society of Internal Medicine during the Nazi period is disenchanting. The society completely subordinated to the Nazi regime. The scientific program of the meetings was oriented to the ideological interests of the regime. Solidarity with nazi-persecuted people is only apparent in rare cases. On the contrary, even DGIM chairmen were involved in expulsions and NS-medical crimes. Cautious criticism was limited to a few areas, such as the “Neue Deutsche Heilkunde” (“New German Healing”) and the study conditions at the universities. Only individual DGIM members developed oppositional behavior on the basis of personal conviction.In accordance with the more recent research on the Nazi era, these results both clarify and broaden the picture of scientific organizations in general and medical societies in particular.


2018 ◽  
Vol 143 (03) ◽  
pp. 201-206
Author(s):  
Ralf Forsbach ◽  
Hans-Georg Hofer

AbstractAlthough times were difficult in 1947/48 – with war damage, travel restrictions and the East-West conflict – the German Society for Internal Medicine not only managed to re-organise itself but also hosted its first scientific congress in that year. The DGIM members Franz Volhard and Paul Martini, who rather disapproved of the Nazi regime, played a decisive role in this process. However, a critical discussion of the NS medical crimes, which occurred just a few years ago, remained the exception. It is interesting to note that members who were persecuted by the NS regime were nevertheless willing to attend a congress that obviously provided a forum for the protagonists of the Nazi era.This work presents – for the first time – an overview of the specific conditions of the reconstitution of the German Society for Internal Medicine and enriches our knowledge about the actions of the medical societies in the years between the fall of the Nazi regime and the founding of the two German states.


VASA ◽  
2017 ◽  
Vol 46 (3) ◽  
pp. 169-176
Author(s):  
Karl-Ludwig Schulte ◽  
Pia M. Jungmann ◽  
Vladimir Makaloski ◽  
Lino Goncalves ◽  
Markus Steinbauer ◽  
...  

Abstract. The prevalence of peripheral artery disease (PAD) is continuously increasing. In addition, the treatment of PAD has changed substantially over the last decades. Novel treatment modalities and diagnostic tools were developed and endovascular therapy was established as a first-line therapy. In consequence, vascular medicine has become an interdisciplinary field, involving different specialties such as internal medicine/cardiology, internal medicine/angiology, vascular surgery, and (interventional) radiology. Attributed to the expanding field and to ensure high quality and standardized training, various curricula were developed. Not only within the different medical disciplines but across countries. We compared the training programmes in Germany, Switzerland, and Europe and found a great variety in these curricula and programmes. Nevertheless, we identified first attempts to harmonize training requirements within the various societies: the interdisciplinary guidelines of the German Society for Cardiology (DGK) and the German Society of Angiology, the adoption of European standards on a national level, and the Swiss initiative of the Union of Vascular Societies of Switzerland (UVSS). The standard and level of training is high in all curricula and societies. However, further harmonization is needed to optimize patient care and ensure a uniform quality level across different vascular societies.


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