Cerebrospinal fluid magnesium level as a prognostic factor in ischaemic stroke

1998 ◽  
Vol 245 (9) ◽  
pp. 584-588 ◽  
Author(s):  
Y. Lampl ◽  
Diklah Geva ◽  
Ronit Gilad ◽  
Yehiel Eshel ◽  
L. Ronen ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Prognostic Factor ◽  
Ischaemic Stroke ◽  
Magnesium Level

Immunophenotyping of cerebrospinal fluid cells in ischaemic stroke

2019 ◽  
Vol 26 (6) ◽  
pp. 919-926 ◽  
Author(s):  
A. Schulte‐Mecklenbeck ◽  
I. Kleffner ◽  
C. Beuker ◽  
T. Wirth ◽  
M. Hartwig ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Ischaemic Stroke ◽  
Cerebrospinal Fluid Cells

Detection of elastin derived peptides in cerebrospinal fluid of patients with first ever ischaemic stroke

Neuropeptides ◽  
2008 ◽  
Vol 42 (3) ◽  
pp. 277-282 ◽  
Author(s):  
G. Nicoloff ◽  
P. Tzvetanov ◽  
P. Christova ◽  
S. Baydanoff
Keyword(s):  
Cerebrospinal Fluid ◽  
Ischaemic Stroke

scholarly journals CTNI-06. SINGLE-CENTER REAL-WORLD ANALYSIS ON CEREBROSPINAL FLUID IN PATIENTS WITH LEPTOMENINGEAL METASTASES OF NON-SMALL CELL LUNG CANCER

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii42-ii42
Author(s):  
Junjie Zhen ◽  
Lei Wen ◽  
Shaoqun Li ◽  
Mingyao Lai ◽  
Zhaoming Zhou ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cerebrospinal Fluid ◽  
Survival Analysis ◽  
Prognostic Factor ◽  
Tumor Cells ◽  
Small Cell ◽  
Leptomeningeal Metastases ◽  
Small Cell Lung ◽  
Cytologic Examination ◽  
Csf Examination

Abstract OBJECTIVE To investigate the clinical values of real-world cerebrospinal fluid (CSF) examination in the diagnosis and prognosis of leptomeningeal metastases (LM) in the patients with non-small cell lung cancer (NSCLC). METHODS The clinical manifestations of patients diagnosed with NSCLC-LM in Guangdong Sanjiu Brain Hospital from 2010 until 2019 and the results from the routine, biochemical and cytologic examinations of their CSF were analyzed retrospectively. Moreover, the effects of different indicators on the prognosis of patients were determined by survival analysis. RESULTS Fifty-eight of the 80 patients underwent CSF examination, and the median values of the initial CSF pressure measured by lumbar puncture was 255mmH2O (60-350mmH2O). Tumor cells were found by the cytologic examination of CSF in 56 of the 58 cases (96.6%). The median levels of protein, glucose, chloride, lactate dehydrogenase (LDH) and carcinoembryonic antigen (CEA) in CSF were 0.4g/L (0–8.3g/L), 2.7mmol/L (0–11.9mmol/L), 120.7mmol/L (0–140.5mmol/L), 21.3U/L (0–221.5U/L) and 31.4ng/ml (0–784.2ng/ml), respectively. Sixteen patients underwent gene detection, and the results showed that there were 4 cases of wild type and 12 cases of mutation type. The survival analysis revealed that the median overall survival (mOS) after being diagnosed with LM, patients in LDH≤37U/L group and those in LDH >37U/L group were 8.0 months, 23.7 months and 4.6 months (P=0.039), respectively, which indicated that the LDH level in CSF was the independent prognostic factor for the survival. CONCLUSION Using the cytologic examination of CSF in patients with LM to detect tumor cells is conducive to the early diagnosis of LM. The high CSF pressure in patients with LM is one of the reasons for the neurologic signs and symptoms. The gene mutations found in the CSF in some patients can be used to guide the further systematic treatment. The LDH level in CSF is the independent prognostic factor affecting the survival.

Multiple sclerosis-associated retrovirus and optic neuritis

2006 ◽  
Vol 12 (3) ◽  
pp. 357-359 ◽  
Author(s):  
S Sotgiu ◽  
G Arru ◽  
M Söderström ◽  
G Mameli ◽  
C Serra ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Prognostic Factor ◽  
Optic Neuritis ◽  
Resonance Imaging ◽  
Specific Study ◽  
Magnetic Resonance Imaging Mri

One prognostic factor for early multiple sclerosis (MS) patients to develop a definite MS may be the presence of the MS-associated retrovirus (MSRV) in the cerebrospinal fluid (CSF). We designed a specific study on a cohort of optic neuritis (ON) patients to evaluate the MSRV-dependent conversion to MS relative to the prediction conferred by magnetic resonance imaging (MRI) and CSF abnormalities. At follow-up, 33.3% MSRV+ and 0% MSRV− ON patients developed MS ( P=0.03). The prediction value is lower than that given by CSF and MRI abnormalities (42.3%). This intriguing finding is discussed in the light of the abundant discrepancies observed in the MSRV literature.

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